Inhibition of c-jun n-terminal kinase after hemorrhage but before resuscitation mitigates hepatic damage and inflammatory response in male rats

Shock

Volumn 32, Issue 5, 2009, Pages 509-516

  Relja, Borna ^a   Schwestka, Birgit ^a   Lee, Veronika Sun Young ^a   Henrich, Dirk ^a   Czerny, Christoph ^a   Borsello, Tiziana ^b   Marzi, Ingo ^a   Lehnert, Mark ^a  

^a GOETHE UNIVERSITY   (Germany)

^b MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

Author keywords

Hemorrhagic shock; Inflammation; JNK inhibition; Liver; Rat; Resuscitation

Indexed keywords

3 NITROTYROSINE; 4 HYDROXYNONENAL; ALANINE AMINOTRANSFERASE; INTERLEUKIN 6; LACTATE DEHYDROGENASE; STRESS ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE INHIBITOR; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BLEEDING; CELL DAMAGE; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME ACTIVITY; ENZYME INHIBITION; HEMORRHAGIC SHOCK; HISTOPATHOLOGY; IMMUNOMODULATION; INFLAMMATION; LIPID PEROXIDATION; LIVER INJURY; LIVER NECROSIS; MALE; NEUTROPHIL CHEMOTAXIS; NITROSATIVE STRESS; NONHUMAN; OXIDATIVE STRESS; RAT; RESUSCITATION;

ALANINE TRANSAMINASE; ANIMALS; APOPTOSIS; IN SITU NICK-END LABELING; INFLAMMATION; INTERLEUKIN-6; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LACTATE DEHYDROGENASES; LIVER; MALE; NECROSIS; PEPTIDES; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; RESUSCITATION; SHOCK, HEMORRHAGIC; TIME FACTORS;

EID: 70350217933     PISSN: 10732322     EISSN: None     Source Type: Journal    
DOI: 10.1097/SHK.0b013e3181a2530d     Document Type: Article

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