The role of eosinophils and neutrophils in inflammation

Clinical and Experimental Allergy, Supplement

Volumn 30, Issue 1, 2000, Pages 22-27

  Sampson, A P ^a  

^a SOUTHAMPTON GENERAL HOSPITAL   (United Kingdom)

Author keywords

Airw ays inflammation; Apoptosis; Asthma; Chemokines; Cytokines; Eosinophil; Leukotrienes; Neutrophil

Indexed keywords

CORTICOSTEROID; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 5; RANTES; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR ALPHA;

AIRWAY OBSTRUCTION; APOPTOSIS; ASTHMA; BRONCHUS MUCOSA; CONFERENCE PAPER; CORTICOSTEROID THERAPY; CYTOKINE RELEASE; DRUG EFFECT; EFFECTOR CELL; EOSINOPHIL; HUMAN; INFLAMMATION; MACROPHAGE ACTIVATION; MEDIATOR RELEASE; NEUTROPHIL; PRIORITY JOURNAL; RECEPTOR DOWN REGULATION;

ASTHMA; EOSINOPHILS; HUMANS; INFLAMMATION; NEUTROPHILS; RESPIRATORY SYSTEM;

EID: 0034043867     PISSN: 09602178     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (27)

1. Coffey MJ, Wheeler CS, Gross KB, Eschenbacher WL, Sporn PH, Peters-Golden M. Increased 5-lipoxygenase metabolism in the lungs of human subjects exposed to ozone. Toxicology 1996; 114:187-97.
2. Fahy JV, Wong HH, Liu JT, Boushey HA. Analysis of induced sputum after air and ozone exposures in healthy subjects. Environ Res 1995; 70:77-83.
3. Smith HR, Larsen GL, Cherniack RM et al. Inflammatory cells and eicosanoid mediators in subjects with late asthmatic responses and increases in airway responsiveness. J Allergy Clin Immunol 1992; 89:1076-84.
4. Teran LM, Carroll M, Frew AJ et al. Neutrophil influx and interleukin-8 release after segmental allergen or saline challenge in asthmatics. Int Arch Allergy Immunol 1995; 107:374-5.
5. Casale TB, Costa JJ, Galli SJ. TN alpha is important in human lung allergic reactions. Am J Respir Cell Mol Biol 1997; 15:35-44.
6. Martin RJ, Cicutto LC, Smith HR, Ballard RD, Szefler SJ. Airways inflammation in nocturnal asthma. Am Rev Respir Dis 1991; 143:351-7.
7. Sur S, Crotty TB, Kephart GM et al. Sudden-onset fatal asthma. A distinct entity with few eosinophils and relatively more neutrophils in the airway submucosa? Am Rev Respir Dis 1993; 148:713-9.
8. Fahy JV, Kim KW, Liu J, Boushey HA. Prominent neutrophilic inflammation in sputum from subjects with asthma exacerbation. J Allergy Clin Immunol 1995; 95:843-52.
9. Lamblin C, Gosset P, Tillie-Leblond I et al. Bronchial neutrophilia in patients with noninfectious status asthmaticus. Am J Respir Crit Care Med 1998; 157:394-402.
10. Wenzel SE, Szefler SJ, Leung DY, Sloan ST, Rex MD, Martin RJ. Bronchoscopic evaluation of severe asthma. Persistent inflammation associated with high dose glucocorticoids. Am J Respir Crit Care Med 1997; 156:737-43.
11. European Network for Understanding the Mechanism of severe Asthma (ENFUMOSA). Cellular composition of induced sputum in severe persistent asthma. Am J Respir Crit Care Med 1999; 159:A700.
12. Alam R. Chemokines in allergic inflammation. J Allergy Clin Immunol 1997; 99:273-7.
13. Sala A et al. The polymorphonuclear leukocyte: a cell tuned for transcellular biosynthesis of cys-leukotrienes. J Physiol Pharmacol 1997; 48:665-73.
14. Yokomizo T, Izumi T, Chang K, Takuwa Y, Shimuzu T. A G-protein-coupled receptor for leukotriene B4 that mediates chemotaxis. Nature 1997; 387:620-4.
15. Stankova J, Rola-Pleszczynski M. Leukotriene B4 stimulates c-fos and c-jun gene transcription and AP-1 binding activity in human monocytes. Biochem J 1992; 282:625-9.
16. Yamaoka KA, Kolb JP. Leukotriene B4 induces interleukin 5 generation from human T lymphocytes. Eur J Immunol 1993; 23:2392-8.
17. Yamaoka KA, Dugas B, Paul-Eugene N, Mencia-Huerta JM, Braquet P, Kolb JP. Leukotriene B4 enhances IL-4-induced IgE production from normal human lymphocytes. Cell Immunol 1994; 156:124-34.
18. Sampson SE, Costello JF, Sampson AP. The effect of inhaled leukotriene B4 in normal and in asthmatic subjects. Am J Respir Crit Care Med 1997; 155:1789-92.
19. Koh YY, Dupuis R, Pollice M, Albertine KH, Fish JE, Peters SP. Neutrophils recruited to the lungs of humans by segmental antigen challenge display and reduced chemotactic response to leukotriene B4. Am J Respir Cell Mol Biol 1993; 8:493-9.
20. Kim CJ, Kanc GC, Zangrilli JG, Cho SK, Koh YY, Peters SP. Eosinophils recruited to the lung by segmental antigen challenge show a reduced chemotactic response to leukotriene B4. Prostaglandins 1994; 47:393-403.
21. Evans PJ, Barnes PJ, Spaethe SM, van Alstyne EL, Mitchell MI, O'Connor BJ. Effects of a leukotriene B4 receptor antagonist, LY293111, on allergen induced responses in asthma. Thorax 1996; 51:1178-84.
22. 2 and PAF. J Clin Invest 1998; 101:890-8.
23. Cox G. Glucocorticoid treatment inhibits apoptosis in human neutrophils: separation of survival and activation outcomes. J Immunol 1995; 154:4719-25.
24. 4 receptor blockade. Am J Respir Crit Care Med 1998; 157: A142.
25. Pouliot M, McDonald PP, Borgeat P, McColl SR. Granulocyte/macrophage colony stimulating factor stimulates the expression of the 5-lipoxygenase-activating protein (FLAP) in human neutrophils. J Exp Med 1994; 179:1225-32.
26. Martin TR, Pistorese BP, Chi EY, Goodman RB, Matthay MA. Effects of leukotriene B4 in the human lung: Recruitment of neutrophils into the alveolar spaces without a change in protein permeability. J Clin Invest 1989; 84:1609-19.
27. Cox G, Crossley J, Xing Z. Macrophage engulfment of apoptotic neutrophils contributes to the resolution of acute pulmonary inflammation in vivo. Am J Respir Cell Mol Biol 1995; 12:28.