Abnormal intracellular accumulation and extracellular Aβ deposition in idiopathic and Dup15q11.2-q13 autism spectrum disorders

PLoS ONE

Volumn 7, Issue 5, 2012, Pages

  Wegiel, Jerzy ^a   Frackowiak, Janusz ^a   Mazur Kolecka, Bozena ^a   Schanen, N Carolyn ^b   Cook, Edwin H ^c   Sigman, Marian ^d   Brown, W Ted ^a   Kuchna, Izabela ^a   Wegiel, Jarek ^a   Nowicki, Krzysztof ^a   Imaki, Humi ^a   Ma, Shuang Yong ^a   Chauhan, Abha ^a   Chauhan, Ved ^a   Miller, David L ^a   Mehta, Pankaj D ^a   Flory, Michael ^a   Cohen, Ira L ^a   London, Eric ^a   Reisberg, Barry ^e   de Leon, Mony J ^e   Wisniewski, Thomas ^a,e   more..

^a NEW YORK STATE INSTITUTE FOR BASIC RESEARCH IN DEVELOPMENTAL DISABILITIES   (United States)

^b NEMOURS ALFRED I DUPONT HOSPITAL FOR CHILDREN   (United States)

^c UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SECRETASE; AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; CELL PROTEIN; LIPOFUSCIN; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1;

ADOLESCENT; ADULT; AMINO TERMINAL SEQUENCE; ARTICLE; ASTROCYTE; AUTISM; AUTOPHAGY; CELL ORGANELLE; CHILD; CHROMOSOME 15Q; CLINICAL ARTICLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ENDOSOME; FEMALE; GENE DUPLICATION; HUMAN; HUMAN TISSUE; INTRACTABLE EPILEPSY; LYSOSOME; MALE; PRESCHOOL CHILD; PREVALENCE; PROTEIN DEGRADATION; SCHOOL CHILD; IMMUNOHISTOCHEMISTRY; METABOLISM; MIDDLE AGED; NERVE CELL; WESTERN BLOTTING;

ADOLESCENT; ADULT; AMYLOID BETA-PEPTIDES; ASTROCYTES; AUTISTIC DISORDER; BLOTTING, WESTERN; CHILD; CHILD DEVELOPMENT DISORDERS, PERVASIVE; CHILD, PRESCHOOL; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MICROSCOPY, CONFOCAL; MIDDLE AGED; NEURONS; YOUNG ADULT;

EID: 84860475483     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0035414     Document Type: Article

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