Nrf2-regulated phase II enzymes are induced by chronic ambient nanoparticle exposure in young mice with age-related impairments

Free Radical Biology and Medicine

Volumn 52, Issue 9, 2012, Pages 2038-2046

  Zhang, Hongqiao ^a   Liu, Honglei ^a   Davies, Kelvin J A ^a   Sioutas, Constantinos ^a   Finch, Caleb E ^a   Morgan, Todd E ^a   Forman, Henry Jay ^a,b  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Aging; Antioxidant; Detoxifying enzyme; Nrf2; Particle

Indexed keywords

BACH1 PROTEIN; GLUTAMATE CYSTEINE LIGASE; HEME OXYGENASE 1; MESSENGER RNA; MYC PROTEIN; NANOPARTICLE; PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE) 1; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

AEROSOL; AGING; ARTICLE; CEREBELLUM; CONTROLLED STUDY; LIVER; LUNG; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

AGING; AIR POLLUTANTS; ANIMALS; BASE SEQUENCE; DNA PRIMERS; ENZYMES; MALE; MICE; MICE, INBRED C57BL; NANOPARTICLES; NF-E2-RELATED FACTOR 2; PARTICLE SIZE;

MUS;

EID: 84860471609     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2012.02.042     Document Type: Article

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