Glutamatergic neurons in rodent models respond to nanoscale particulate urban air pollutants in vivo and in vitro

Environmental Health Perspectives

Volumn 119, Issue 7, 2011, Pages 1003-1009

  Morgan, Todd E ^a   Davis, David A ^a   Iwata, Nahoko ^a   Tanner, Jeremy A ^b   Snyder, David ^b   Ning, Zhi ^c   Kam, Winnie ^c   Hsu, Yu Tien ^b,d   Winkler, Jeremy W ^b,d   Chen, Jiu Chiuan ^e   Petasis, Nicos A ^b,d   Baudry, Michel ^b,d   Sioutas, Constantinos ^c   Finch, Caleb E ^a,d  

^a Davis School of Gerontology   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c Viterbi School of Engineering ^*  (United States)

^d Department of Neurobiology ^*  (United States)

^e UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Air pollution; Cultured cells; Free radical; Glia; Glutamate receptor; Inhalation; Nanoscale particulate air pollutants; Neuroinflammation; Neuron; Neurotoxicity

Indexed keywords

2 AMINO 5 PHOSPHONOVALERIC ACID; FREE RADICAL; GLUTAMATE RECEPTOR; GLUTAMATE RECEPTOR A1; INTERLEUKIN 1ALPHA; N METHYL DEXTRO ASPARTIC ACID; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

AEROSOL; AIR POLLUTANT; AIR POLLUTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; AQUEOUS SOLUTION; ARTICLE; BRAIN CORTEX; BRAIN ISCHEMIA; CELL ACTIVATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; ELECTRON SPIN RESONANCE; EMBRYO; ENVIRONMENTAL EXPOSURE; EXCITOTOXICITY; GLIA CELL; GLUTAMATERGIC NERVE CELL; GROWTH INHIBITION; HIPPOCAMPAL SLICE; HIPPOCAMPUS; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NANOSCALE PARTICULATE AIR POLLUTANT; NERVE CELL; NERVE FIBER GROWTH; NERVE FUNCTION; NEUROTOXICITY; NEWBORN; NONHUMAN; PARTICULATE MATTER; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN INDUCTION; RAT; TISSUE SLICE; URBAN AREA;

2-AMINO-5-PHOSPHONOVALERATE; ANIMALS; BRAIN ISCHEMIA; CELLS, CULTURED; CEREBRAL CORTEX; GLUTAMIC ACID; HIPPOCAMPUS; INHALATION EXPOSURE; INTERLEUKIN-1ALPHA; MALE; MICE; MICE, INBRED C57BL; N-METHYLASPARTATE; NEUROGLIA; NEURONS; PARTICULATE MATTER; RATS; RECEPTORS, AMPA; RNA, MESSENGER; TUMOR NECROSIS FACTOR-ALPHA; VEHICLE EMISSIONS;

MUS; RATTUS; RODENTIA;

EID: 79960052594     PISSN: 00916765     EISSN: 15529924     Source Type: Journal    
DOI: 10.1289/ehp.1002973     Document Type: Article

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