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Volumn 20, Issue 10, 2012, Pages 3317-3322

A comparative study of backbone versus side chain peptide cyclization: Application for HIV-1 integrase inhibitors

(7) Hayouka, Zvi a Levin, Aviad a,b Hurevich, Mattan a,c Shalev, Deborah E a Loyter, Abraham a Gilon, Chaim a Friedler, Assaf a

a HEBREW UNIVERSITY OF JERUSALEM (Israel)

b UNIVERSITY OF ALBERTA (Canada)

c MAX PLANCK INSTITUTE OF COLLOIDS AND INTERFACES (Germany)

Author keywords

Cyclic peptides; HIV 1; Integrase; LEDGF; Peptides

Indexed keywords

INTEGRASE INHIBITOR;

ALKYLATION; ARTICLE; BACKBONE PEPTIDE CYCLIZATION; BINDING AFFINITY; CATALYSIS; COMPARATIVE STUDY; CONTROLLED STUDY; CYCLIZATION; DRUG DESIGN; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; HUMAN IMMUNODEFICIENCY VIRUS 1; NUCLEAR MAGNETIC RESONANCE; SIDE CHAIN PEPTIDE CYCLIZATION; VIRUS REPLICATION;

AMINO ACID SEQUENCE; ENZYME ACTIVATION; HELA CELLS; HIV INTEGRASE INHIBITORS; HIV-1; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEPTIDE LIBRARY; PEPTIDES, CYCLIC;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 84860437198 PISSN: 09680896 EISSN: 14643391 Source Type: Journal
DOI: 10.1016/j.bmc.2012.03.039 Document Type: Article

Times cited : (14)

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