-
1
-
-
76149112233
-
The battlefield of perforin/granzyme cell death pathways
-
Hoves, S., J. A. Trapani, and I. Voskoboinik. 2010. The battlefield of perforin/granzyme cell death pathways. J. Leukoc. Biol. 87: 237-243.
-
(2010)
J. Leukoc. Biol.
, vol.87
, pp. 237-243
-
-
Hoves, S.1
Trapani, J.A.2
Voskoboinik, I.3
-
2
-
-
77951681958
-
Cytotoxic and non-cytotoxic roles of the CTL/NK protease granzyme B
-
Afonina, I. S., S. P. Cullen, and S. J. Martin. 2010. Cytotoxic and non-cytotoxic roles of the CTL/NK protease granzyme B. Immunol. Rev. 235: 105-116.
-
(2010)
Immunol. Rev.
, vol.235
, pp. 105-116
-
-
Afonina, I.S.1
Cullen, S.P.2
Martin, S.J.3
-
3
-
-
33846147328
-
Granzymes at a glance
-
DOI 10.1242/jcs.03239
-
Bots, M., and J. P. Medema. 2006. Granzymes at a glance. J. Cell Sci. 119: 5011-5014. (Pubitemid 46085180)
-
(2006)
Journal of Cell Science
, vol.119
, Issue.24
, pp. 5011-5014
-
-
Bots, M.1
Medema, J.P.2
-
4
-
-
0141853015
-
The orphan granzymes of humans and mice
-
DOI 10.1016/S0952-7915(03)00099-2
-
Grossman, W. J., P. A. Revell, Z. H. Lu, H. Johnson, A. J. Bredemeyer, and T. J. Ley. 2003. The orphan granzymes of humans and mice. Curr. Opin. Immunol. 15: 544-552. (Pubitemid 37130195)
-
(2003)
Current Opinion in Immunology
, vol.15
, Issue.5
, pp. 544-552
-
-
Grossman, W.J.1
Revell, P.A.2
Lu, Z.H.3
Johnson, H.4
Bredemeyer, A.J.5
Ley, T.J.6
-
5
-
-
0036863736
-
The secretory synapse: The secrets of a serial killer
-
DOI 10.1034/j.1600-065X.2002.18913.x
-
Bossi, G., C. Trambas, S. Booth, R. Clark, J. Stinchcombe, and G. M. Griffiths. 2002. The secretory synapse: the secrets of a serial killer. Immunol. Rev. 189: 152-160. (Pubitemid 35448950)
-
(2002)
Immunological Reviews
, vol.189
, pp. 152-160
-
-
Bossi, G.1
Trambas, C.2
Booth, S.3
Clark, R.4
Stinchcombe, J.5
Griffiths, G.M.6
-
6
-
-
0037341354
-
Caspase activation by granzyme B is indirect, and caspase autoprocessing requires the release of proapoptotic mitochondrial factors
-
DOI 10.1016/S1074-7613(03)00050-5
-
Sutton, V. R., M. E. Wowk, M. Cancilla, and J. A. Trapani. 2003. Caspase activation by granzyme B is indirect, and caspase autoprocessing requires the release of proapoptotic mitochondrial factors. Immunity 18: 319-329. (Pubitemid 36351513)
-
(2003)
Immunity
, vol.18
, Issue.3
, pp. 319-329
-
-
Sutton, V.R.1
Wowk, M.E.2
Cancilla, M.3
Trapani, J.A.4
-
7
-
-
0025905925
-
Cytotoxic T lymphocyte granules are secretory lysosomes, containing both perforin and granzymes
-
Peters, P. J., J. Borst, V. Oorschot, M. Fukuda, O. Krähenbühl, J. Tschopp, J. W. Slot, and H. J. Geuze. 1991. Cytotoxic T lymphocyte granules are secretory lysosomes, containing both perforin and granzymes. J. Exp. Med. 173: 1099-1109.
-
(1991)
J. Exp. Med.
, vol.173
, pp. 1099-1109
-
-
Peters, P.J.1
Borst, J.2
Oorschot, V.3
Fukuda, M.4
Krähenbühl, O.5
Tschopp, J.6
Slot, J.W.7
Geuze, H.J.8
-
8
-
-
0033499729
-
Cytosolic delivery of granzyme B by bacterial toxins: Evidence that endosomal disruption, in addition to transmembrane pore formation, is an important function of perforin
-
Browne, K. A., E. Blink, V. R. Sutton, C. J. Froelich, D. A. Jans, and J. A. Trapani. 1999. Cytosolic delivery of granzyme B by bacterial toxins: evidence that endosomal disruption, in addition to transmembrane pore formation, is an important function of perforin. Mol. Cell. Biol. 19: 8604-8615. (Pubitemid 30414053)
-
(1999)
Molecular and Cellular Biology
, vol.19
, Issue.12
, pp. 8604-8615
-
-
Browne, K.A.1
Blink, E.2
Sutton, V.R.3
Froelich, C.J.4
Jans, D.A.5
Trapani, J.A.6
-
9
-
-
34247592342
-
Apoptosis induced by the lymphocyte effector molecule perforin
-
DOI 10.1016/j.coi.2007.04.007, PII S0952791507000593, Lymphocyte activation/Lymphocyte effector functions
-
Bolitho, P., I. Voskoboinik, J. A. Trapani, and M. J. Smyth. 2007. Apoptosis induced by the lymphocyte effector molecule perforin. Curr. Opin. Immunol. 19: 339-347. (Pubitemid 46687012)
-
(2007)
Current Opinion in Immunology
, vol.19
, Issue.3
, pp. 339-347
-
-
Bolitho, P.1
Voskoboinik, I.2
Trapani, J.A.3
Smyth, M.J.4
-
10
-
-
0025169597
-
Cell specificity of granzyme gene expression
-
Garcia-Sanz, J. A., H. R. MacDonald, D. E. Jenne, J. Tschopp, and M. Nabholz. 1990. Cell specificity of granzyme gene expression. J. Immunol. 145: 3111-3118. (Pubitemid 20382588)
-
(1990)
Journal of Immunology
, vol.145
, Issue.9
, pp. 3111-3118
-
-
Garcia-Sanz, J.A.1
MacDonald, H.R.2
Jenne, D.E.3
Tschopp, J.4
Nabholz, M.5
-
11
-
-
0028875927
-
Granzyme B and perforin lytic proteins are expressed in CD34+ peripheral blood progenitor cells mobilized by chemotherapy and granulocyte colony-stimulating factor
-
Berthou, C., J. P. Marolleau, C. Lafaurie, A. Soulié, L. Dal Cortivo, J. F. Bourge, M. Benbunan, and M. Sasportes. 1995. Granzyme B and perforin lytic proteins are expressed in CD34+ peripheral blood progenitor cells mobilized by chemotherapy and granulocyte colony-stimulating factor. Blood 86: 3500-3506.
-
(1995)
Blood
, vol.86
, pp. 3500-3506
-
-
Berthou, C.1
Marolleau, J.P.2
Lafaurie, C.3
Soulié, A.4
Dal Cortivo, L.5
Bourge, J.F.6
Benbunan, M.7
Sasportes, M.8
-
12
-
-
0031307603
-
Acquisition of Granzyme B and Fas Ligand Proteins by Human Keratinocytes Contributes to Epidermal Cell Defense
-
Berthou, C., L. Michel, A. Soulié, F. Jean-Louis, B. Flageul, L. Dubertret, F. Sigaux, Y. Zhang, and M. Sasportes. 1997. Acquisition of granzyme B and Fas ligand proteins by human keratinocytes contributes to epidermal cell defense. J. Immunol. 159: 5293-5300. (Pubitemid 127470055)
-
(1997)
Journal of Immunology
, vol.159
, Issue.11
, pp. 5293-5300
-
-
Berthou, C.1
Michel, L.2
Soulie, A.3
Jean-Louis, F.4
Flageul, B.5
Dubertret, L.6
Sigaux, F.7
Zhang, Y.8
Sasportes, M.9
-
13
-
-
33749315904
-
Granzyme B, a novel mediator of allergic inflammation: Its induction and release in blood basophils and human asthma
-
DOI 10.1182/blood-2006-03-010348
-
Tschopp, C. M., N. Spiegl, S. Didichenko, W. Lutmann, P. Julius, J. C. Virchow, C. E. Hack, and C. A. Dahinden. 2006. Granzyme B, a novel mediator of allergic inflammation: its induction and release in blood basophils and human asthma. Blood 108: 2290-2299. (Pubitemid 44497512)
-
(2006)
Blood
, vol.108
, Issue.7
, pp. 2290-2299
-
-
Tschopp, C.M.1
Spiegl, N.2
Didichenko, S.3
Lutmann, W.4
Julius, P.5
Virchow, J.C.6
Hack, C.E.7
Dahinden, C.A.8
-
14
-
-
34248589178
-
Human mast cells produce and release the cytotoxic lymphocyte associated protease granzyme B upon activation
-
DOI 10.1016/j.molimm.2007.03.024, PII S0161589007001344
-
Strik, M. C., P. J. de Koning, M. J. Kleijmeer, B. A. Bladergroen, A. M. Wolbink, J. M. Griffith, D. Wouters, Y. Fukuoka, L. B. Schwartz, C. E. Hack, et al. 2007. Human mast cells produce and release the cytotoxic lymphocyte associated protease granzyme B upon activation. Mol. Immunol. 44: 3462-3472. (Pubitemid 46754451)
-
(2007)
Molecular Immunology
, vol.44
, Issue.14
, pp. 3462-3472
-
-
Strik, M.C.M.1
De Koning, P.J.A.2
Kleijmeer, M.J.3
Bladergroen, B.A.4
Wolbink, A.M.5
Griffith, J.M.6
Wouters, D.7
Fukuoka, Y.8
Schwartz, L.B.9
Hack, C.E.10
Van Ham, S.M.11
Kummer, J.A.12
-
15
-
-
77949529017
-
Granzyme B produced by human plasmacytoid dendritic cells suppresses T-cell expansion
-
Jahrsdorfer, B., A. Vollmer, S. E. Blackwell, J. Maier, K. Sontheimer, T. Beyer, B. Mandel, O. Lunov, K. Tron, G. U. Nienhaus, et al. 2010. Granzyme B produced by human plasmacytoid dendritic cells suppresses T-cell expansion. Blood 115: 1156-1165.
-
(2010)
Blood
, vol.115
, pp. 1156-1165
-
-
Jahrsdorfer, B.1
Vollmer, A.2
Blackwell, S.E.3
Maier, J.4
Sontheimer, K.5
Beyer, T.6
Mandel, B.7
Lunov, O.8
Tron, K.9
Nienhaus, G.U.10
-
16
-
-
68149099548
-
Human B cells secrete granzyme B when recognizing viral antigens in the context of the acute phase cytokine IL-21
-
Hagn, M., E. Schwesinger, V. Ebel, K. Sontheimer, J. Maier, T. Beyer, T. Syrovets, Y. Laumonnier, D. Fabricius, T. Simmet, and B. Jahrsdörfer. 2009. Human B cells secrete granzyme B when recognizing viral antigens in the context of the acute phase cytokine IL-21. J. Immunol. 183: 1838-1845.
-
(2009)
J. Immunol.
, vol.183
, pp. 1838-1845
-
-
Hagn, M.1
Schwesinger, E.2
Ebel, V.3
Sontheimer, K.4
Maier, J.5
Beyer, T.6
Syrovets, T.7
Laumonnier, Y.8
Fabricius, D.9
Simmet, T.10
Jahrsdörfer, B.11
-
17
-
-
84859947465
-
Human B cells differentiate into granzyme B-secreting cytotoxic B lymphocytes upon incomplete T-cell help
-
In press
-
Hagn, M., K. Sontheimer, K. Dahlke, S. Brueggemann, C. Kaltenmeier, T. Beyer, S. Hofmann, O. Lunov, T. F. Barth, D. Fabricius, et al. 2011. Human B cells differentiate into granzyme B-secreting cytotoxic B lymphocytes upon incomplete T-cell help. Immunol. Cell Biol. In press.
-
(2011)
Immunol. Cell Biol.
-
-
Hagn, M.1
Sontheimer, K.2
Dahlke, K.3
Brueggemann, S.4
Kaltenmeier, C.5
Beyer, T.6
Hofmann, S.7
Lunov, O.8
Barth, T.F.9
Fabricius, D.10
-
18
-
-
33750626239
-
B-chronic lymphocytic leukemia cells and other B cells can produce granzyme B and gain cytotoxic potential after interleukin-21-based activation
-
Jahrsdörfer, B., S. E. Blackwell, J. E. Wooldridge, J. Huang, M. W. Andreski, L. S. Jacobus, C. M. Taylor, and G. J. Weiner. 2006. B-chronic lymphocytic leukemia cells and other B cells can produce granzyme B and gain cytotoxic potential after interleukin-21-based activation. Blood 108: 2712-2719.
-
(2006)
Blood
, vol.108
, pp. 2712-2719
-
-
Jahrsdörfer, B.1
Blackwell, S.E.2
Wooldridge, J.E.3
Huang, J.4
Andreski, M.W.5
Jacobus, L.S.6
Taylor, C.M.7
Weiner, G.J.8
-
19
-
-
77954122576
-
CD5+ B cells from individuals with systemic lupus erythematosus express granzyme B
-
Hagn, M., V. Ebel, K. Sontheimer, E. Schwesinger, O. Lunov, T. Beyer, D. Fabricius, T. F. Barth, A. Viardot, S. Stilgenbauer, et al. 2010. CD5+ B cells from individuals with systemic lupus erythematosus express granzyme B. Eur. J. Immunol. 40: 2060-2069.
-
(2010)
Eur. J. Immunol.
, vol.40
, pp. 2060-2069
-
-
Hagn, M.1
Ebel, V.2
Sontheimer, K.3
Schwesinger, E.4
Lunov, O.5
Beyer, T.6
Fabricius, D.7
Barth, T.F.8
Viardot, A.9
Stilgenbauer, S.10
-
20
-
-
0030925491
-
The extent of affinity maturation differs between the memory and antibody-forming cell compartments in the primary immune response
-
DOI 10.1093/emboj/16.11.2996
-
Smith, K. G., A. Light, G. J. Nossal, and D. M. Tarlinton. 1997. The extent of affinity maturation differs between the memory and antibody-forming cell compartments in the primary immune response. EMBO J. 16: 2996-3006. (Pubitemid 27234939)
-
(1997)
EMBO Journal
, vol.16
, Issue.11
, pp. 2996-3006
-
-
Smith, K.G.C.1
Light, A.2
Nossal, G.J.V.3
Tarlinton, D.M.4
-
21
-
-
0032100720
-
+ T cells in primary and secondary influenza pneumonia
-
DOI 10.1016/S1074-7613(00)80573-7
-
Flynn, K. J., G. T. Belz, J. D. Altman, R. Ahmed, D. L. Woodland, and P. C. Doherty. 1998. Virus-specific CD8+ T cells in primary and secondary influenza pneumonia. Immunity 8: 683-691. (Pubitemid 28294515)
-
(1998)
Immunity
, vol.8
, Issue.6
, pp. 683-691
-
-
Flynn, K.J.1
Belz, G.T.2
Altman, J.D.3
Ahmed, R.4
Woodland, D.L.5
Doherty, P.C.6
-
22
-
-
33845591750
-
+ T cells specific for a model latency-associated antigen fail to control a gammaherpesvirus in vivo
-
DOI 10.1002/eji.200636164
-
Smith, C. M., G. T. Rosa, J. S. May, N. J. Bennett, A. M. Mount, G. T. Belz, and P. G. Stevenson. 2006. CD4+ T cells specific for a model latency-associated antigen fail to control a gammaherpesvirus in vivo. Eur. J. Immunol. 36: 3186-3197. (Pubitemid 44932720)
-
(2006)
European Journal of Immunology
, vol.36
, Issue.12
, pp. 3186-3197
-
-
Smith, C.M.1
Rosa, G.T.L.2
May, J.S.3
Bennett, N.J.4
Mouni, A.M.5
Belz, G.T.6
Stevenson, P.G.7
-
23
-
-
23244440046
-
Properties of phytohaemagglutinin
-
Kolodny, R. L., and K. Hirschhorn. 1964. Properties of phytohaemagglutinin. Nature 201: 715-716.
-
(1964)
Nature
, vol.201
, pp. 715-716
-
-
Kolodny, R.L.1
Hirschhorn, K.2
-
24
-
-
84965821924
-
Phytohemagglutinin: An initiator of mitosis in cultures of normal human leukocytes
-
Nowell, P. C. 1960. Phytohemagglutinin: an initiator of mitosis in cultures of normal human leukocytes. Cancer Res. 20: 462-466.
-
(1960)
Cancer Res.
, vol.20
, pp. 462-466
-
-
Nowell, P.C.1
-
25
-
-
0037407425
-
Purification of natural killer cell cytotoxic granules for assaying target cell apoptosis
-
DOI 10.1016/S0022-1759(03)00077-2
-
Davis, J. E., V. R. Sutton, K. A. Browne, and J. A. Trapani. 2003. Purification of natural killer cell cytotoxic granules for assaying target cell apoptosis. J. Immunol. Methods 276: 59-68. (Pubitemid 36513837)
-
(2003)
Journal of Immunological Methods
, vol.276
, Issue.1-2
, pp. 59-68
-
-
Davis, J.E.1
Sutton, V.R.2
Browne, K.A.3
Trapani, J.A.4
-
26
-
-
0042377711
-
The human cytotoxic T cell granule serine protease granzyme H has chymotrypsin-like (chymase) activity and is taken up into cytoplasmic vesicles reminiscent of granzyme B-containing endosomes
-
Edwards, K. M., C. M. Kam, J. C. Powers, and J. A. Trapani. 1999. The human cytotoxic T cell granule serine protease granzyme H has chymotrypsin-like (chymase) activity and is taken up into cytoplasmic vesicles reminiscent of granzyme B-containing endosomes. J. Biol. Chem. 274: 30468-30473.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 30468-30473
-
-
Edwards, K.M.1
Kam, C.M.2
Powers, J.C.3
Trapani, J.A.4
-
27
-
-
77149142640
-
IL-21 regulates germinal center B cell differentiation and proliferation through a B cell-intrinsic mechanism
-
Zotos, D., J. M. Coquet, Y. Zhang, A. Light, K. D'Costa, A. Kallies, L. M. Corcoran, D. I. Godfrey, K. M. Toellner, M. J. Smyth, et al. 2010. IL-21 regulates germinal center B cell differentiation and proliferation through a B cell-intrinsic mechanism. J. Exp. Med. 207: 365-378.
-
(2010)
J. Exp. Med.
, vol.207
, pp. 365-378
-
-
Zotos, D.1
Coquet, J.M.2
Zhang, Y.3
Light, A.4
D'Costa, K.5
Kallies, A.6
Corcoran, L.M.7
Godfrey, D.I.8
Toellner, K.M.9
Smyth, M.J.10
-
28
-
-
33746255647
-
Extracellular granzymes: Current perspectives
-
DOI 10.1515/BC.2006.106, PII BCHM3877827
-
Buzza, M. S., and P. I. Bird. 2006. Extracellular granzymes: current perspectives. Biol. Chem. 387: 827-837. (Pubitemid 44100229)
-
(2006)
Biological Chemistry
, vol.387
, Issue.7
, pp. 827-837
-
-
Buzza, M.S.1
Bird, P.I.2
-
29
-
-
78649917559
-
Granzyme B-induced apoptosis in cancer cells and its regulation (review)
-
[review]
-
Rousalova, I., and E. Krepela. 2010. Granzyme B-induced apoptosis in cancer cells and its regulation (review). [review] Int. J. Oncol. 37: 1361-1378.
-
(2010)
Int. J. Oncol.
, vol.37
, pp. 1361-1378
-
-
Rousalova, I.1
Krepela, E.2
-
30
-
-
77949529810
-
Granzyme B cleavage of autoantigens in autoimmunity
-
Darrah, E., and A. Rosen. 2010. Granzyme B cleavage of autoantigens in autoimmunity. Cell Death Differ. 17: 624-632.
-
(2010)
Cell Death Differ.
, vol.17
, pp. 624-632
-
-
Darrah, E.1
Rosen, A.2
-
32
-
-
17044413339
-
Altered migration, recruitment, and somatic hypermutation in the early response of marginal zone B cells to T cell-dependent antigen
-
Phan, T. G., S. Gardam, A. Basten, and R. Brink. 2005. Altered migration, recruitment, and somatic hypermutation in the early response of marginal zone B cells to T cell-dependent antigen. J. Immunol. 174: 4567-4578.
-
(2005)
J. Immunol.
, vol.174
, pp. 4567-4578
-
-
Phan, T.G.1
Gardam, S.2
Basten, A.3
Brink, R.4
-
33
-
-
29144519767
-
IL-21 induces differentiation of human naive and memory B cells into antibody-secreting plasma cells
-
Ettinger, R., G. P. Sims, A. M. Fairhurst, R. Robbins, Y. S. da Silva, R. Spolski, W. J. Leonard, and P. E. Lipsky. 2005. IL-21 induces differentiation of human naive and memory B cells into antibody-secreting plasma cells. J. Immunol. 175: 7867-7879. (Pubitemid 41798347)
-
(2005)
Journal of Immunology
, vol.175
, Issue.12
, pp. 7867-7879
-
-
Ettinger, R.1
Sims, G.P.2
Fairhurst, A.-M.3
Robbins, R.4
Da Silva, Y.S.5
Spolski, R.6
Leonard, W.J.7
Lipsky, P.E.8
-
34
-
-
33749522228
-
ERK signaling is a molecular switch integrating opposing inputs from B cell receptor and T cell cytokines to control TLR4-driven plasma cell differentiation
-
Rui, L., J. I. Healy, J. Blasioli, and C. C. Goodnow. 2006. ERK signaling is a molecular switch integrating opposing inputs from B cell receptor and T cell cytokines to control TLR4-driven plasma cell differentiation. J. Immunol. 177: 5337-5346. (Pubitemid 44527606)
-
(2006)
Journal of Immunology
, vol.177
, Issue.8
, pp. 5337-5346
-
-
Rui, L.1
Healy, J.I.2
Blasioli, J.3
Goodnow, C.C.4
-
35
-
-
47949086920
-
Quantitative regulation of B cell division destiny by signal strength
-
Turner, M. L., E. D. Hawkins, and P. D. Hodgkin. 2008. Quantitative regulation of B cell division destiny by signal strength. J. Immunol. 181: 374-382.
-
(2008)
J. Immunol.
, vol.181
, pp. 374-382
-
-
Turner, M.L.1
Hawkins, E.D.2
Hodgkin, P.D.3
-
36
-
-
0028258577
-
Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells
-
DOI 10.1016/0092-8674(94)90376-X
-
Heusel, J. W., R. L. Wesselschmidt, S. Shresta, J. H. Russell, and T. J. Ley. 1994. Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells. Cell 76: 977-987. (Pubitemid 24106379)
-
(1994)
Cell
, vol.76
, Issue.6
, pp. 977-987
-
-
Heusel, J.W.1
Wesselschmidt, R.L.2
Shresta, S.3
Russell, J.H.4
Ley, T.J.5
-
37
-
-
0033178379
-
CTL granules: Evolution of vesicles essential for combating virus infections
-
DOI 10.1016/S0167-5699(99)01488-7, PII S0167569999014887
-
Trapani, J. A., V. R. Sutton, and M. J. Smyth. 1999. CTL granules: evolution of vesicles essential for combating virus infections. Immunol. Today 20: 351-356. (Pubitemid 29356428)
-
(1999)
Immunology Today
, vol.20
, Issue.8
, pp. 351-356
-
-
Trapani, J.A.1
Sutton, V.R.2
Smyth, M.J.3
-
38
-
-
0033598718
-
Granzymes are the essential downstream effector molecules for the control of primary virus infections by cytolytic leukocytes
-
Müllbacher, A., P. Waring, R. Tha Hla, T. Tran, S. Chin, T. Stehle, C. Museteanu, and M. M. Simon. 1999. Granzymes are the essential downstream effector molecules for the control of primary virus infections by cytolytic leukocytes. Proc. Natl. Acad. Sci. USA 96: 13950-13955.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 13950-13955
-
-
Müllbacher, A.1
Waring, P.2
Tha Hla, R.3
Tran, T.4
Chin, S.5
Stehle, T.6
Museteanu, C.7
Simon, M.M.8
-
39
-
-
0030723209
-
In vitro- and ex vivo-derived cytolytic leukocytes from granzyme A X B double knockout mice are defective in granule-mediated apoptosis but not lysis of target cells
-
DOI 10.1084/jem.186.10.1781
-
Simon, M. M., M. Hausmann, T. Tran, K. Ebnet, J. Tschopp, R. ThaHla, and A. Müllbacher. 1997. In vitro- and ex vivo-derived cytolytic leukocytes from granzyme A x B double knockout mice are defective in granule-mediated apoptosis but not lysis of target cells. J. Exp. Med. 186: 1781-1786. (Pubitemid 27506292)
-
(1997)
Journal of Experimental Medicine
, vol.186
, Issue.10
, pp. 1781-1786
-
-
Simon, M.M.1
Hausmann, M.2
Tran, T.3
Ebnet, K.4
Tschopp, J.5
ThaHla, R.6
Mullbacher, A.7
-
40
-
-
14244257818
-
Early appearance of germinal center-derived memory B cells and plasma cells in blood after primary immunization
-
DOI 10.1084/jem.20042060
-
Blink, E. J., A. Light, A. Kallies, S. L. Nutt, P. D. Hodgkin, and D. M. Tarlinton. 2005. Early appearance of germinal center-derived memory B cells and plasma cells in blood after primary immunization. J. Exp. Med. 201: 545-554. (Pubitemid 40289545)
-
(2005)
Journal of Experimental Medicine
, vol.201
, Issue.4
, pp. 545-554
-
-
Blink, E.J.1
Light, A.2
Kallies, A.3
Nutt, S.L.4
Hodgkin, P.D.5
Tarlinton, D.M.6
-
41
-
-
0037446534
-
Architectural defects in the spleens of Nkx2-3-deficient mice are intrinsic and associated with defects in both B cell maturation and T cell-dependent immune responses
-
Tarlinton, D., A. Light, D. Metcalf, R. P. Harvey, and L. Robb. 2003. Architectural defects in the spleens of Nkx2-3-deficient mice are intrinsic and associated with defects in both B cell maturation and T cell-dependent immune responses. J. Immunol. 170: 4002-4010. (Pubitemid 36428161)
-
(2003)
Journal of Immunology
, vol.170
, Issue.8
, pp. 4002-4010
-
-
Tarlinton, D.1
Light, A.2
Metcalf, D.3
Harvey, R.P.4
Robb, L.5
-
42
-
-
0030587934
-
The xid Mutation Diminishes Memory B Cell Generation but Does Not Affect Somatic Hypermutation and Selection
-
Ridderstad, A., G. J. Nossal, and D. M. Tarlinton. 1996. The xid mutation diminishes memory B cell generation but does not affect somatic hypermutation and selection. J. Immunol. 157: 3357-3365. (Pubitemid 126449147)
-
(1996)
Journal of Immunology
, vol.157
, Issue.8
, pp. 3357-3365
-
-
Ridderstad, A.1
Nossal, G.J.V.2
Tarlinton, D.M.3
-
43
-
-
33751252804
-
The major human and mouse granzymes are structurally and functionally divergent
-
DOI 10.1083/jcb.200606073
-
Kaiserman, D., C. H. Bird, J. Sun, A. Matthews, K. Ung, J. C. Whisstock, P. E. Thompson, J. A. Trapani, and P. I. Bird. 2006. The major human and mouse granzymes are structurally and functionally divergent. J. Cell Biol. 175: 619-630. (Pubitemid 44790615)
-
(2006)
Journal of Cell Biology
, vol.175
, Issue.4
, pp. 619-630
-
-
Kaiserman, D.1
Bird, C.H.2
Sun, J.3
Matthews, A.4
Ung, K.5
Whisstock, J.C.6
Thompson, P.E.7
Trapani, J.A.8
Bird, P.I.9
-
44
-
-
33947496416
-
Mouse and human granzyme B have distinct tetrapeptide specificities and abilities to recruit the bid pathway
-
DOI 10.1074/jbc.M606564200
-
Casciola-Rosen, L., M. Garcia-Calvo, H. G. Bull, J. W. Becker, T. Hines, N. A. Thornberry, and A. Rosen. 2007. Mouse and human granzyme B have distinct tetrapeptide specificities and abilities to recruit the bid pathway. J. Biol. Chem. 282: 4545-4552. (Pubitemid 47100932)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.7
, pp. 4545-4552
-
-
Casciola-Rosen, L.1
Garcia-Calvo, M.2
Bull, H.G.3
Becker, J.W.4
Hines, T.5
Thornberry, N.A.6
Rosen, A.7
-
45
-
-
33846946478
-
Human and murine granzyme B exhibit divergent substrate preferences
-
Cullen, S. P., C. Adrain, A. U. Lüthi, P. J. Duriez, and S. J. Martin. 2007. Human and murine granzyme B exhibit divergent substrate preferences. J. Cell Biol. 176: 435-444.
-
(2007)
J. Cell Biol.
, vol.176
, pp. 435-444
-
-
Cullen, S.P.1
Adrain, C.2
Lüthi, A.U.3
Duriez, P.J.4
Martin, S.J.5
-
46
-
-
0029847228
-
Long-range disruption of gene expression by a selectable marker cassette
-
DOI 10.1073/pnas.93.23.13090
-
Pham, C. T., D. M. MacIvor, B. A. Hug, J. W. Heusel, and T. J. Ley. 1996. Long-range disruption of gene expression by a selectable marker cassette. Proc. Natl. Acad. Sci. USA 93: 13090-13095. (Pubitemid 26382774)
-
(1996)
Proceedings of the National Academy of Sciences of the United States of America
, vol.93
, Issue.23
, pp. 13090-13095
-
-
Pham, C.T.N.1
Macivor, D.M.2
Hug, B.A.3
Heusel, J.W.4
Ley, T.J.5
-
47
-
-
13544266566
-
Granzyme B and the downstream granzymes C and/or F are important for cytotoxic lymphocyte functions
-
Revell, P. A., W. J. Grossman, D. A. Thomas, X. Cao, R. Behl, J. A. Ratner, Z. H. Lu, and T. J. Ley. 2005. Granzyme B and the downstream granzymes C and/or F are important for cytotoxic lymphocyte functions. J. Immunol. 174: 2124-2131. (Pubitemid 40223956)
-
(2005)
Journal of Immunology
, vol.174
, Issue.4
, pp. 2124-2131
-
-
Revell, P.A.1
Grossman, W.J.2
Thomas, D.A.3
Cao, X.4
Behl, R.5
Ratner, J.A.6
Lu, Z.H.7
Ley, T.J.8
-
48
-
-
2942700101
-
Discordant regulation of granzyme H and granzyme B expression in human lymphocytes
-
DOI 10.1074/jbc.M312481200
-
Sedelies, K. A., T. J. Sayers, K. M. Edwards, W. Chen, D. G. Pellicci, D. I. Godfrey, and J. A. Trapani. 2004. Discordant regulation of granzyme H and granzyme B expression in human lymphocytes. J. Biol. Chem. 279: 26581-26587. (Pubitemid 38798814)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.25
, pp. 26581-26587
-
-
Sedelies, K.A.1
Sayers, T.J.2
Edwards, K.M.3
Chen, W.4
Pellicci, D.G.5
Godfrey, D.I.6
Trapani, J.A.7
-
49
-
-
0035215769
-
Perforin-independent expression of granzyme B and proteinase inhibitor 9 in human testis and placenta suggests a role for granzyme B-mediated proteolysis in reproduction
-
Hirst, C. E., M. S. Buzza, V. R. Sutton, J. A. Trapani, K. L. Loveland, and P. I. Bird. 2001. Perforin-independent expression of granzyme B and proteinase inhibitor 9 in human testis and placenta suggests a role for granzyme B-mediated proteolysis in reproduction. Mol. Hum. Reprod. 7: 1133-1142. (Pubitemid 33150208)
-
(2001)
Molecular Human Reproduction
, vol.7
, Issue.12
, pp. 1133-1142
-
-
Hirst, C.E.1
Buzza, M.S.2
Sutton, V.R.3
Trapani, J.A.4
Loveland, K.L.5
Bird, P.I.6
-
50
-
-
9744227188
-
Granzyme N, a novel granzyme, is expressed in spermatocytes and spermatids of the mouse testis
-
DOI 10.1095/biolreprod.104.030452
-
Takano, N., H. Matusi, and T. Takahashi. 2004. Granzyme N, a novel granzyme, is expressed in spermatocytes and spermatids of the mouse testis. Biol. Reprod. 71: 1785-1795. (Pubitemid 39586921)
-
(2004)
Biology of Reproduction
, vol.71
, Issue.6
, pp. 1785-1795
-
-
Takano, N.1
Matusi, H.2
Takahashi, T.3
-
51
-
-
34547133231
-
The granzyme B gene is highly polymorphic in wild mice but essentially invariant in common inbred laboratory strains
-
DOI 10.1111/j.1399-0039.2007.00872.x
-
Thia, K. Y., and J. A. Trapani. 2007. The granzyme B gene is highly polymorphic in wild mice but essentially invariant in common inbred laboratory strains. Tissue Antigens 70: 198-204. (Pubitemid 47106643)
-
(2007)
Tissue Antigens
, vol.70
, Issue.3
, pp. 198-204
-
-
Thia, K.Y.T.1
Trapani, J.A.2
-
52
-
-
0344406761
-
A triple-mutated allele of granzyme B incapable of inducing apoptosis
-
DOI 10.1073/pnas.0437935100
-
McIlroy, D., P. F. Cartron, P. Tuffery, Y. Dudoit, A. Samri, B. Autran, F. M. Vallette, P. Debré, and I. Theodorou. 2003. A triple-mutated allele of granzyme B incapable of inducing apoptosis. Proc. Natl. Acad. Sci. USA 100: 2562-2567. (Pubitemid 36297538)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.5
, pp. 2562-2567
-
-
McIlroy, D.1
Cartron, P.-F.2
Tuffery, P.3
Dudoit, Y.4
Samri, A.5
Autran, B.6
Vallette, F.M.7
Debre, P.8
Theodorou, I.9
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