Human mast cells produce and release the cytotoxic lymphocyte associated protease granzyme B upon activation

Molecular Immunology

Volumn 44, Issue 14, 2007, Pages 3462-3472

  Strik, Merel C M ^a,b   de Koning, Pieter J A ^c   Kleijmeer, Monique J ^c   Bladergroen, Bellinda A ^a,d   Wolbink, Angela M ^b   Griffith, Janice M ^c   Wouters, Dorine ^a   Fukuoka, Yoshihiro ^e   Schwartz, Lawrence B ^e   Hack, C Erik ^a,b   van Ham, S Marieke ^b   Kummer, J Alain ^c  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^b SANQUIN RESEARCH   (Netherlands)

^c UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^d RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^e VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Granzyme B; IgE; Mast cells; SERPINB9; Substance P

Indexed keywords

ACETIC ACID DERIVATIVE; CALCIMYCIN; COMPOUND 48-80; GRANZYME B; IMMUNOGLOBULIN E;

ADULT; ARTICLE; CELL GRANULE; CELL STRUCTURE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOTOXIC LYMPHOCYTE; ENZYME ACTIVATION; ENZYME RELEASE; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; INFANT; LYMPHOCYTE ACTIVATION; MALE; MAST CELL; PRESCHOOL CHILD; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SKIN CELL; UMBILICAL CORD BLOOD;

ADULT; ANTIGENS; CELLS, CULTURED; ENZYME INDUCTION; FEMALE; GENE EXPRESSION REGULATION; GRANZYMES; HUMANS; INFANT; LYSOSOMES; MALE; MAST CELLS; MASTOCYTOSIS; MEMBRANE GLYCOPROTEINS; MIDDLE AGED; PORE FORMING CYTOTOXIC PROTEINS; RNA, MESSENGER; SECRETORY VESICLES; SERPINS; TRYPTASES;

EID: 34248589178     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2007.03.024     Document Type: Article

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