Thermodynamic and kinetic stabilities of active site protonation states of class C β-lactamase

Journal of Physical Chemistry B

Volumn 116, Issue 16, 2012, Pages 4741-4753

  Tripathi, Ravi ^a   Nair, Nisanth N ^a  

^a INDIAN INSTITUTE OF TECHNOLOGY KANPUR   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYMES; KINETICS; MOLECULAR DYNAMICS; PROTON TRANSFER; THERMODYNAMIC STABILITY;

ACTIVE SITE; ACTIVE SITE RESIDUES; CEPHALOTHIN; DYNAMIC PROTONATION; EQUILIBRIUM STRUCTURES; EXPERIMENTAL OBSERVATION; KINETIC STABILITY; LACTAMASES; MOLECULAR DYNAMICS SIMULATIONS; MOLECULAR LEVELS; PROTON SHUTTLE; PROTONATED; PROTONATION STATE; QUANTUM MECHANICAL; ROOM TEMPERATURE; STRUCTURAL CHANGE;

PROTONATION;

BETA LACTAMASE; PROTON;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; ENZYME ACTIVE SITE; KINETICS; METABOLISM; MOLECULAR DYNAMICS; THERMODYNAMICS;

BETA-LACTAMASES; CATALYTIC DOMAIN; KINETICS; MOLECULAR DYNAMICS SIMULATION; MOLECULAR STRUCTURE; PROTONS; THERMODYNAMICS;

EID: 84860290610     PISSN: 15206106     EISSN: 15205207     Source Type: Journal    
DOI: 10.1021/jp212186q     Document Type: Article

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