Crystal structure of BRL 42715, C6-(N1-Methyl-1,2,3-triazolylmethylene) penem, in complex with Enterobacter cloacae 908R β-lactamase: Evidence for a stereoselective mechanism from docking studies

Journal of the American Chemical Society

Volumn 127, Issue 10, 2005, Pages 3262-3263

  Michaux, Catherine ^a   Charlier, Paulette ^b   Frère, Jean Marie ^b   Wouters, Johan ^a  

^a UNIVERSITY OF NAMUR   (Belgium)

^b UNIVERSITY OF LIÈGE   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

6 (1 METHYL 1,2,3 TRIAZOL 4 YLMETHYLENE)PENEM 3 CARBOXYLIC ACID; BETA LACTAM ANTIBIOTIC; BETA LACTAMASE; C6 (N1 METHYL 1,2,3 TRIAZOLYLMETHYLENE)PENEM; UNCLASSIFIED DRUG;

ARTICLE; CRYSTAL STRUCTURE; DRUG STRUCTURE; ENTEROBACTER CLOACAE; STEREOCHEMISTRY;

BETA-LACTAMASES; CRYSTALLOGRAPHY, X-RAY; ENTEROBACTER CLOACAE; LACTAMS; MODELS, MOLECULAR; STEREOISOMERISM; THERMODYNAMICS;

EID: 14944358169     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja0426241     Document Type: Article

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