Matrix metalloproteinase-9, -10, and -12, MDM2 and p53 expression in mouse liver during dimethylnitrosamine-induced oxidative stress and genomic injury

Molecular and Cellular Biochemistry

Volumn 365, Issue 1-2, 2012, Pages 351-361

  Syed, Ismail ^a   Rathod, Jasmine ^b   Parmar, Mayur ^b   Corcoran, George B ^c   Ray, Sidhartha D ^b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b MANCHESTER UNIVERSITY   (United States)

^c WAYNE STATE UNIVERSITY   (United States)

Author keywords

Apoptosis; Dimethylnitrosamine; Extracellular matrix; Hepatotoxicity; Matrix metalloproteinases; MDM2; Necrosis; Oxidative stress; P53; PCNA

Indexed keywords

CARCINOGEN; DIMETHYLNITROSAMINE; DNA; GELATINASE B; MACROPHAGE ELASTASE; PROTEIN MDM2; PROTEIN P53; STROMELYSIN 2; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CHEMICAL CARCINOGENESIS; CONTROLLED STUDY; EXTRACELLULAR MATRIX; HISTOPATHOLOGY; LIVER; LIVER CANCER; LIVER CELL; LIVER NECROSIS; LIVER TOXICITY; MALE; MORTALITY; MOUSE; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; WESTERN BLOTTING;

ALANINE TRANSAMINASE; ANIMALS; APOPTOSIS; CARCINOGENS; DIMETHYLNITROSAMINE; DNA FRAGMENTATION; GENE EXPRESSION; LIVER; MALE; MALONDIALDEHYDE; MATRIX METALLOPROTEINASES, SECRETED; MICE; MICE, INBRED C3H; NECROSIS; OXIDATIVE STRESS; PROTO-ONCOGENE PROTEINS C-MDM2; THIOBARBITURIC ACID REACTIVE SUBSTANCES; TUMOR SUPPRESSOR PROTEIN P53;

MUS;

EID: 84860254902     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-012-1277-z     Document Type: Article

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