How guanylate-binding proteins achieve assembly-stimulated processive cleavage of GTP to GMP

Nature

Volumn 440, Issue 7080, 2006, Pages 101-104

  Ghosh, Agnidipta ^a,c   Praefcke, Gerrit J K ^a,d   Renault, Louis ^b   Wittinghofer, Alfred ^a   Herrmann, Christian ^a,e  

^a MAX PLANCK INSTITUTE OF MOLECULAR PHYSIOLOGY   (Germany)

^b LABORATOIRE D ENZYMOLOGIE ET BIOCHIMIE STRUCTURALES   (France)

^c MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^d UNIVERSITY OF COLOGNE   (Germany)

^e RUHR UNIVERSITY BOCHUM   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS; DIMERIZATION; ENZYMES; HUMAN ENGINEERING; HYDROLYSIS;

GTP-BINDING PROTEINS; GUANINE BASE INTERACTIONS; NUCLEOTIDE-DEPENDENT HOMODIMERIZATION;

PROTEINS;

GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE PHOSPHATE; GUANOSINE TRIPHOSPHATE; INTERFERON;

CELLS AND CELL COMPONENTS;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; BINDING SITE; BIOCHEMISTRY; CATALYSIS; CRYSTAL STRUCTURE; DIMERIZATION; HYDROLYSIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN ISOLATION; STRUCTURE ANALYSIS;

EID: 33644772427     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature04510     Document Type: Article

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