Myeloid blood CD11C+ dendritic cells and monocyte-derived dendritic cells differ in their ability to stimulate T lymphocytes

Blood

Volumn 100, Issue 8, 2002, Pages 2858-2866

  Osugi, Yuko ^a,b   Vuckovic, Slavica ^a,b   Hart, Derek N J ^a,b  

^a OSAKA UNIVERSITY   (Japan)

^b MATER MEDICAL RESEARCH INSTITUTE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOPROTEIN P 15095; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 4; KEYHOLE LIMPET HEMOCYANIN;

ALLOGENEIC RESTRICTION; ANTIGEN PRESENTING CELL; ARTICLE; CELL LABELING; CELL PROLIFERATION; CELL SELECTION; CELL STRUCTURE; CONTROLLED STUDY; DENDRITIC CELL; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOTHERAPY; MIXED LYMPHOCYTE REACTION; MONOCYTE; ONTOGENY; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION;

EID: 0037108304     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.V100.8.2858     Document Type: Article

References (52)

1. Hart DNJ. Dendritic cells: unique leukocyte populations which control the primary immune response. Blood. 1997;90:3245-3287.
2. Banchereau J, Steinman RM. Dendritic cells and the control of immunity. Nature. 1998;392:245-252.
3. Nestle FO, Banchereau J, Hart D. Dendritic cells: on the move from bench to bedside. Nat Med. 2001;7:761-765.
4. Robinson S, Patterson S, English N, et al. Human peripheral blood contains two distinct lineages of dendritic cells. Eur J Immunol. 1999;29:2769-2778.
5. Cella M, Jarrossay D, Facchietti F, et al. Plasmacytoid monocytes migrate to inflamed lymph nodes and produce large amounts of type I interferon. Nature Med. 1999;8:919-929.
6. Schakel K, Mayer E, Federle C, et al. A novel dendritic cell population in human blood: one-step immunomagnetic isolation by a specific mAb (M-DC8) and in vitro priming of cytotoxic T lymphocytes. Eur J Immunol. 1998;28:4084-4093.
7. Crawford K, Gabuzda D, Pantazopoulos V, et al. Circulating CD2+ monocytes are dendritic cells. J Immunol. 1999;163:5920-5928.
8. McLellan AD, Heiser A, Sorg RV, Fearnley DB, Hart DNJ. Dermal dendritic cells associated with T lymphocytes in normal human skin display an activated phenotype. J Invest Dermatol. 1998; 111:841-849.
9. Ito T, Inaba M, Inaba K, et al. A CD1a+/CD11c+ subset of human blood dendritic cells is a direct precursor of Langerhans cells, J Immunol. 1999; 163:1409-1419.
10. Hart DNJ, Clark GJ, MacDonald K, et al: 7th leucocyte differentiation antigen workshop DC section summary. In: Mason D, ed. Leucocyte Typing VII. Oxford: Oxford University Press; 2000.
11. Sallusto F, Lanzavecchia A. Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumour necrosis factor-α. J Exp Med. 1994;179:1109-1118.
12. + dendritic cells. Proc Natl Acad Sci U S A. 1996;93: 2588-2592.
13. Vuckovic S, Fearnley DB, Mannering SI, et al. Generation of CMRF-44+ monocyte-derived dendritic cells: insights into phenotype and function. Exp Hematol. 1998;26:1255-1264.
14. Thurner B, Roder C, Dieckmann D, et al. Generation of large numbers of fully mature and stable dendritic cells from leukapheresis products for clinical application. J Immunol Methods. 1999; 223:1-15.
15. Randolph GJ, Inaba K, Robbiani DF, Steinman RM, Muller WA. Differentiation of phagocytic monocytes into lymph node dendritic cells in vivo. Immunity. 1999;11:753-761.
16. Ho CS, Lopez JA, Vuckovic S, et al. Surgical and physical stress increases circulating blood dendritic cell counts independently of monocyte counts, Blood. 2001;98:140-145.
17. Olweus J, BitMansour A, Warnke R, et al. Dendritic cell ontogeny: a human dendritic cell lineage of myeloid origin. Proc Natl Acad Sci U S A. 1997; 94:12551-12556.
18. Kadowaki N, Antonenko S, Lau JY, Liu YJ. Natural interferon alpha/beta-producing cells link innate and adaptive immunity. J Exp Med. 2000; 192:219-226.
19. Hsu FJ, Benike C, Fagnoni F, et al. Vaccination of patients with B-cell lymphoma using autologous antigen-pulsed dendritic cells. Nat Med. 1996;2: 52-57.
20. Cao H, Verge V, Baron C, et al. In vitro generation of dendritic cells from human blood monocytes in experimental conditions compatible for in vivo cell therapy. J Hematother Stem Cell Res. 2000;9: 183-194.
21. Dhodapkar MV, Steinman RM, Krasovsky J, Munz M, Bhardwaj N. Antigen-specific inhabition of effector T cell function in humans after injection of immature dendritic cells. J Exp Med. 2001;193: 233-238.
22. Fong L, Brockstedt D, Benike C, Wu L, Engleman EG. Dendritic cells injected via different routes induce immunity in cancer patients. J Immunol. 2001;166:4254-4259.
23. Fearnley DB, McLellan AD, Mannering SI, Hock BD, Hart DNJ. Isolation of human blood dendritic cells using the CMRF-44 monoclonal antibody: implications for studies on antigen presenting cell function and immunotherapy. Blood. 1997;89: 3708-3716.
24. Hock BD, Fearnley DB, Boyce A, et al. Human dendritic cells express a 95kDa activation/differentiation antigen defined by CMRF-56. Tissue Antigens. 1999;53:320-334.
25. Reichardt VL, Okada CY, Liso A, et al. Idiotype vaccination using dendritic cells after autologous peripheral blood stem cell transplantation for multiple myeloma: a feasibility study. Blood. 1999;93: 2411-2419.
26. Anton D, Dabadghao S, Palucka K, Holm G, Yi Q. Generation of dendritic cells from peripheral blood adherent cells in medium with human serum. Scand J Immunol. 1998;47:116-121.
27. Mannering SI, McKenzie JL, Hart DNJ. Optimisation of the conditions for generating human DC initiated primary antigen specific T lymphocyte lines in vitro. J Immunol Methods. 1998;219:69-83.
28. Hsu FJ, Benike C, Fagnoni F, et al. Vaccination of patients with B-cell lymphoma using autologous antigen-pulsed dendritic cells. Nat Med. 1996;2: 52-58.
29. McLellan AD, Starling GC, Hari DNJ. Isolation of human blood dendritic cells by Nycodenz discontinuous gradient centrifugation. J Immunol Methods. 1995;184:81-89.
30. O'Doherty U, Steinman RM, Peng M, et al. Dendritic cells freshly isolated from human blood express CD4 and mature into typical immunostimulatory dendritic cells after culture in monocyteconditioned medium. J Exp Med. 1993;178:1067-1076.
31. Palucka KA, Taquet N, Sanchez-Chapuis F, Gluckman JC. Dendritic cells as the terminal stage of monocyte differentiation. J Immunol. 1998;160:4587-4595.
32. MacDonald KPA, Munster D, Clark G, Vuckovic S, Hart DNJ. Peripheral blood dendritic cell subset analysis. In: Mason D, ed. Leucocyte Typing VII. Oxford: Oxford University Press; 2000.
33. Turville S, Arthos J, MacDonald K, et al. HIV gp120 receptors on human dendritic cells. Blood. 2001;98:2482-2488.
34. Kato M, Neil TK, Fearnley DB, et al. Expression of multilectin receptors and comparative FITC-dextran uptake by human dendritic cells. Int Immunol. 2000;12:1511-1519.
35. Liu YJ, Kanzler H, Soumelis V, Gilliet M. Dendritic cell lineage, plasticity and cross-regulation. Nat Immunol. 2001;2:585-589.
36. Sozzani S, Luini W, Borsatti A, et al. Receptor expression and responsiveness of human dendritic cells to a defined set of CC and CXC chemokines. J Immunol. 1997;159:1993-2000.
37. Steinman RM, Gutchinov B, Witmer MD, Nussenweig MC. Dendritic cells are the principal stimulators of the primary mixed lymphocyte reaction in mice. J Exp Med. 1983;147:613-627.
38. McKenzie JL, Calder VC, Starling GC, Hart DNJ. Role of tumor necrosis factor α in dendritic cell mediated primary mixed leukocyte reactions. Bone Marrow Transplant. 1995;15:163-171.
39. Siegal FP, Kadowaki N, Shodell M, et al. The nature of the principal type 1 interferon-producing cells in human blood. Science. 1999;284:1835-1837.
40. Kadowaki N, Antonenko S, Liu YJ. Distinct CpG DNA and polyinosinic-polycytidylic acid doublestranded RNA, respectively, stimulate CD11c(-) type 2 dendritic cell precursors and CD11c(+) dendritic cells to produce type I IFN. J Immunol. 2001;166:2291-2295.
41. Kalinski P, Schuitemaker J, Hilkens C, Wierenga E, Kapsenberg M. Final maturation of dendritic cells is associated with impaired responsiveness in IFN-gamma and to bacterial IL-12 inducers: decreased ability of mature dendritic cells to produce IL-12 during the interaction with Th cells. J Immunol. 1999;162:3231-3236.
42. Langenkamp A, Messi M, Lanzavecchia A, Sallusto F. Kinetics of dendritic cell activation: impact on priming of TH1, TH2 and nonpolarized T cells. J Immunol. 2000;1:311-316.
43. Tanaka H, Demeure CE, Rubio M, Delespesse G, Sarfati M. Human monocyte-derived dendritic cells induce naive T cell differentiation into T helper cell type 2 (Th2) or Th1/Th2 effectors: role of stimulator/responder ratio. J Exp Med. 2000; 192:405-412.
44. Cella M, Facchetti F, Lanzavecchia A, Cotonna M. Plasmacytoid dendritic cells activated by influenza virus and CD40L drive a potent TH1 polarization. J Immunol. 2000;1:305-310.
45. Zou W, Borvak J, Marches F, et al. Macrophagederived dendritic cells have strong Th1-polarizing potential mediated by beta-chemokines rather than IL-12. J Immunol. 2000;165:4388-4396.
46. Tang HLI, Cyster JG. Chemokine up-regulation and activated T cell attraction by maturing dendritic cells. Science. 1999;284:819-822.
47. Lanzavecchia A, Sallusto F. Antigen decoding by T lymphocytes: from synapses to fate determination. Nat Immunol. 2001;2:487-492.
48. Sallusto F, Lenig D, Förster R, Lipp M, Lanzavecchia A. Two subsets of memory T lymphocytes with distinct homing potentials and effector functions. Nature. 1999;401:708-712.
49. Valitutti S, Muller S, Dessing M, Lanzavecchia A. Signal extinction and T cell repolarization in T helper cell-antigen-presenting cell conjugates. Eur J Immunol. 1996;26:2012-2016.
50. Fearnley DB, Whyte LF, Carnoutsos SA, Cook AH, Hart DN. Monitoring human blood dendritic cell numbers in normal individuals and in stem cell transplantation. Blood. 1999;93:728-736.
51. Lopez JA, Crosbie GV, Kelly C, et al. Monitoring and isolation of blood dendritic cells from apheresis products in healthy individuals: a platform for cancer immunotherapy. J Immunol Methods. In Press.
52. Lopez JA, Bioley G, Turtle CJ, et al. Single step isolation of blood DC by positive immunoselection. J Immunol Methods. In press.