-
1
-
-
33846006906
-
HER-2 and NF-κB as the targets for therapy-resistant breast cancer
-
Ahmed KM, Cao N, Li JJ (2006) HER-2 and NF-kappaB as the targets for therapy-resistant breast cancer. Anticancer Res 26:4235-4243 (Pubitemid 46039582)
-
(2006)
Anticancer Research
, vol.26
, Issue.6 B
, pp. 4235-4243
-
-
Ahmed, K.M.1
Cao, N.2
Li, J.J.3
-
2
-
-
34547562418
-
Frequent engagement of the classical and alternative NF-κB pathways by diverse genetic abnormalities in multiple myeloma
-
DOI 10.1016/j.ccr.2007.07.004, PII S1535610807002036
-
Annunziata CM, Davis RE, Demchenko Y, Bellamy W, Gabrea A, Zhan F, Lenz G, Hanamura I, Wright G, Xiao W, Dave S, Hurt EM, Tan B, Zhao H, Stephens O, Santra M, Williams DR, Dang L, Barlogie B, Shaughnessy JD Jr, Kuehl WM, Staudt LM (2007) Frequent engagement of the classical and alternative NF-kappaB pathways by diverse genetic abnormalities in multiple myeloma. Cancer Cell 12:115-130 (Pubitemid 47199123)
-
(2007)
Cancer Cell
, vol.12
, Issue.2
, pp. 115-130
-
-
Annunziata, C.M.1
Davis, R.E.2
Demchenko, Y.3
Bellamy, W.4
Gabrea, A.5
Zhan, F.6
Lenz, G.7
Hanamura, I.8
Wright, G.9
Xiao, W.10
Dave, S.11
Hurt, E.M.12
Tan, B.13
Zhao, H.14
Stephens, O.15
Santra, M.16
Williams, D.R.17
Dang, L.18
Barlogie, B.19
Shaughnessy Jr., J.D.20
Kuehl, W.M.21
Staudt, L.M.22
more..
-
3
-
-
26444584958
-
Nuclear factor-kappaB and liver carcinogenesis
-
Arsura M, Cavin LG (2005) Nuclear factor-kappaB and liver carcinogenesis. Cancer Lett 229:157-169
-
(2005)
Cancer Lett
, vol.229
, pp. 157-169
-
-
Arsura, M.1
Cavin, L.G.2
-
4
-
-
0030613532
-
Nuclear factor-κB/Rel blocks transforming growth factor β1-induced apoptosis of murine hepatocyte cell lines
-
Arsura M, FitzGerald MJ, Fausto N, Sonenshein GE (1997) Nuclear factor-kappaB/Rel blocks transforming growth factor beta1-induced apoptosis of murine hepatocyte cell lines. Cell Growth Differ 8:1049-1059 (Pubitemid 27433293)
-
(1997)
Cell Growth and Differentiation
, vol.8
, Issue.10
, pp. 1049-1059
-
-
Arsura, M.1
FitzGerald, M.J.2
Fausto, N.3
Sonenshein, G.E.4
-
5
-
-
36949005417
-
DNA damage signalling guards against activated oncogenes and tumour progression
-
DOI 10.1038/sj.onc.1210881, PII 1210881
-
Bartek J, Bartkova J, Lukas J (2007) DNA damage signalling guards against activated oncogenes and tumour progression. Oncogene 26:7773-7779 (Pubitemid 350242463)
-
(2007)
Oncogene
, vol.26
, Issue.56
, pp. 7773-7779
-
-
Bartek, J.1
Bartkova, J.2
Lukas, J.3
-
6
-
-
0029059060
-
Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kappa B
-
Beg AA, Sha WC, Bronson RT, Ghosh S, Baltimore D (1995) Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kappa B. Nature 376:167-170
-
(1995)
Nature
, vol.376
, pp. 167-170
-
-
Beg, A.A.1
Sha, W.C.2
Bronson, R.T.3
Ghosh, S.4
Baltimore, D.5
-
7
-
-
0030817061
-
Inhibition of NF-κB activity induces apoptosis in murine hepatocytes
-
Bellas RE, FitzGerald MJ, Fausto N, Sonenshein GE (1997) Inhibition of NF-kappa B activity induces apoptosis in murine hepatocytes. Am J Pathol 151:891-896 (Pubitemid 27424296)
-
(1997)
American Journal of Pathology
, vol.151
, Issue.4
, pp. 891-896
-
-
Bellas, R.E.1
FitzGerald, M.J.2
Fausto, N.3
Sonenshein, G.E.4
-
8
-
-
77952107213
-
TAK1 suppresses a NEMO-dependent but NF-kappaB-independent pathway to liver cancer
-
Bettermann K, Vucur M, Haybaeck J, Koppe C, Janssen J, Heymann F, Weber A, Weiskirchen R, Liedtke C, Gassler N, Muller M, de Vos R, Wolf MJ, Boege Y, Seleznik GM, Zeller N, Erny D, Fuchs T, Zoller S, Cairo S, Buendia MA, Prinz M, Akira S, Tacke F, Heikenwalder M, Trautwein C, Luedde T (2010) TAK1 suppresses a NEMO-dependent but NF-kappaB-independent pathway to liver cancer. Cancer Cell 17:481-496
-
(2010)
Cancer Cell
, vol.17
, pp. 481-496
-
-
Bettermann, K.1
Vucur, M.2
Haybaeck, J.3
Koppe, C.4
Janssen, J.5
Heymann, F.6
Weber, A.7
Weiskirchen, R.8
Liedtke, C.9
Gassler, N.10
Muller, M.11
De Vos, R.12
Wolf, M.J.13
Boege, Y.14
Seleznik, G.M.15
Zeller, N.16
Erny, D.17
Fuchs, T.18
Zoller, S.19
Cairo, S.20
Buendia, M.A.21
Prinz, M.22
Akira, S.23
Tacke, F.24
Heikenwalder, M.25
Trautwein, C.26
Luedde, T.27
more..
-
9
-
-
0033539885
-
Increased expression of p50-NF-κB and constitutive activation of NF-κB transcription factors during mouse skin carcinogenesis
-
Budunova IV, Perez P, Vaden VR, Spiegelman VS, Slaga TJ, Jorcano JL (1999) Increased expression of p50-NF-kappaB and constitutive activation of NF-kappaB transcription factors during mouse skin carcinogenesis. Oncogene 18:7423-7431 (Pubitemid 30035043)
-
(1999)
Oncogene
, vol.18
, Issue.52
, pp. 7423-7431
-
-
Budunova, I.V.1
Perez, P.2
Vaden, V.R.3
Spiegelman, V.S.4
Slaga, T.J.5
Jorcano, J.L.6
-
10
-
-
34249799899
-
Genome-wide analysis of gene expression in T cells to identify targets of the NF-κB transcription factor c-Rel
-
Bunting K, Rao S, Hardy K, Woltring D, Denyer GS, Wang J, Gerondakis S, Shannon MF (2007) Genome-wide analysis of gene expression in T cells to identify targets of the NF-kappa B transcription factor c-Rel. J Immunol 178:7097-7109 (Pubitemid 46847436)
-
(2007)
Journal of Immunology
, vol.178
, Issue.11
, pp. 7097-7109
-
-
Bunting, K.1
Rao, S.2
Hardy, K.3
Woltring, D.4
Denyer, G.S.5
Wang, J.6
Gerondalds, S.7
Shannon, M.F.8
-
11
-
-
68749103771
-
The NF-kappaB-independent functions of IKK subunits in immunity and cancer
-
Chariot A (2009) The NF-kappaB-independent functions of IKK subunits in immunity and cancer. Trends Cell Biol 19:404-413
-
(2009)
Trends Cell Biol
, vol.19
, pp. 404-413
-
-
Chariot, A.1
-
12
-
-
0037108089
-
Role of Rel/NF-kappaB transcription factors in apoptosis of human hepatocellular carcinoma cells
-
Chiao PJ, Na R, Niu J, Sclabas GM, Dong Q, Curley SA (2002) Role of Rel/NF-kappaB transcription factors in apoptosis of human hepatocellular carcinoma cells. Cancer 95:1696-1705
-
(2002)
Cancer
, vol.95
, pp. 1696-1705
-
-
Chiao, P.J.1
Na, R.2
Niu, J.3
Sclabas, G.M.4
Dong, Q.5
Curley, S.A.6
-
13
-
-
0032980504
-
Absence of tumor necrosis factor rescues RelA-deficient mice from embryonic lethality
-
DOI 10.1073/pnas.96.6.2994
-
Doi TS, Marino MW, Takahashi T, Yoshida T, Sakakura T, Old LJ, Obata Y (1999) Absence of tumor necrosis factor rescues RelA-deficient mice from embryonic lethality. Proc Natl Acad Sci USA 96:2994-2999 (Pubitemid 29148832)
-
(1999)
Proceedings of the National Academy of Sciences of the United States of America
, vol.96
, Issue.6
, pp. 2994-2999
-
-
Doi, T.S.1
Marino, M.W.2
Takahashi, T.3
Yoshida, T.4
Sakakura, T.5
Old, L.J.6
Obata, Y.7
-
14
-
-
0033545541
-
Rising incidence of hepatocellular carcinoma in the United States
-
DOI 10.1056/NEJM199903113401001
-
El-Serag HB, Mason AC (1999) Rising incidence of hepatocellular carcinoma in the United States. N Engl J Med 340:745-750 (Pubitemid 29114292)
-
(1999)
New England Journal of Medicine
, vol.340
, Issue.10
, pp. 745-750
-
-
El-Serag, H.B.1
Mason, A.C.2
-
15
-
-
34250020201
-
Hepatocellular carcinoma: Epidemiology and molecular carcinogenesis
-
DOI 10.1053/j.gastro.2007.04.061, PII S0016508507007998
-
El-Serag HB, Rudolph KL (2007) Hepatocellular carcinoma: epidemiology and molecular carcinogenesis. Gastroenterology 132:2557-2576 (Pubitemid 46890874)
-
(2007)
Gastroenterology
, vol.132
, Issue.7
, pp. 2557-2576
-
-
El-Serag, H.B.1
Rudolph, K.L.2
-
16
-
-
33747830764
-
Hepatocellular carcinoma pathogenesis: From genes to environment
-
DOI 10.1038/nrc1934, PII NRC1934
-
Farazi PA, DePinho RA (2006) Hepatocellular carcinoma pathogenesis: from genes to environment. Nat Rev Cancer 6:674-687 (Pubitemid 44286000)
-
(2006)
Nature Reviews Cancer
, vol.6
, Issue.9
, pp. 674-687
-
-
Farazi, P.A.1
DePinho, R.A.2
-
17
-
-
0036735241
-
Hepatocellular carcinoma and markers of apoptosis (bcl-2, bax, bcl-x): Prognostic significance
-
DOI 10.1097/00022744-200209000-00004
-
Garcia EJ, Lawson D, Cotsonis G, Cohen C (2002) Hepatocellular carcinoma and markers of apoptosis (bcl-2, bax, bcl-x): prognostic significance. Appl Immunohistochem Mol Morphol 10:210-217 (Pubitemid 34988527)
-
(2002)
Applied Immunohistochemistry and Molecular Morphology
, vol.10
, Issue.3
, pp. 210-217
-
-
Garcia, E.J.1
Lawson, D.2
Cotsonis, G.3
Cohen, C.4
-
18
-
-
4043088499
-
IKKβ links inflammation and tumorigenesis in a mouse model of colitis-associated cancer
-
DOI 10.1016/j.cell.2004.07.013, PII S0092867404006713
-
Greten FR, Eckmann L, Greten TF, Park JM, Li ZW, Egan LJ, Kagnoff MF, Karin M (2004) IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer. Cell 118:285-296 (Pubitemid 39061110)
-
(2004)
Cell
, vol.118
, Issue.3
, pp. 285-296
-
-
Greten, F.R.1
Eckmann, L.2
Greten, T.F.3
Park, J.M.4
Li, Z.-W.5
Egan, L.J.6
Kagnoff, M.F.7
Karin, M.8
-
19
-
-
70349568358
-
A lymphotoxin-driven pathway to hepatocellular carcinoma
-
Haybaeck J, Zeller N, Wolf MJ, Weber A, Wagner U, Kurrer MO, Bremer J, Iezzi G, Graf R, Clavien PA, Thimme R, Blum H, Nedospasov SA, Zatloukal K, Ramzan M, Ciesek S, Pietschmann T, Marche PN, Karin M, Kopf M, Browning JL, Aguzzi A, Heikenwalder M (2009) A lymphotoxin-driven pathway to hepatocellular carcinoma. Cancer Cell 16:295-308
-
(2009)
Cancer Cell
, vol.16
, pp. 295-308
-
-
Haybaeck, J.1
Zeller, N.2
Wolf, M.J.3
Weber, A.4
Wagner, U.5
Kurrer, M.O.6
Bremer, J.7
Iezzi, G.8
Graf, R.9
Clavien, P.A.10
Thimme, R.11
Blum, H.12
Nedospasov, S.A.13
Zatloukal, K.14
Ramzan, M.15
Ciesek, S.16
Pietschmann, T.17
Marche, P.N.18
Karin, M.19
Kopf, M.20
Browning, J.L.21
Aguzzi, A.22
Heikenwalder, M.23
more..
-
20
-
-
74549217325
-
Hepatocyte IKKbeta/NF-kappaB inhibits tumor promotion and progression by preventing oxidative stress-driven STAT3 activation
-
He G, Yu GY, Temkin V, Ogata H, Kuntzen C, Sakurai T, Sieghart W, Peck-Radosavljevic M, Leffert HL, Karin M (2010) Hepatocyte IKKbeta/NF-kappaB inhibits tumor promotion and progression by preventing oxidative stress-driven STAT3 activation. Cancer Cell 17:286-297
-
(2010)
Cancer Cell
, vol.17
, pp. 286-297
-
-
He, G.1
Yu, G.Y.2
Temkin, V.3
Ogata, H.4
Kuntzen, C.5
Sakurai, T.6
Sieghart, W.7
Peck-Radosavljevic, M.8
Leffert, H.L.9
Karin, M.10
-
21
-
-
13844259181
-
Chronic lymphocytic inflammation specifies the organ tropism of prions
-
DOI 10.1126/science.1106460
-
Heikenwalder M, Zeller N, Seeger H, Prinz M, Klohn PC, Schwarz P, Ruddle NH, Weissmann C, Aguzzi A (2005) Chronic lymphocytic inflammation specifies the organ tropism of prions. Science 307:1107-1110 (Pubitemid 40262116)
-
(2005)
Science
, vol.307
, Issue.5712
, pp. 1107-1110
-
-
Heikenwalder, M.1
Zeller, N.2
Seeger, H.3
Prinz, M.4
Klohn, P.-C.5
Schwarz, P.6
Ruddle, N.H.7
Weissmann, C.8
Aguzzi, A.9
-
22
-
-
57349090407
-
Gene expression in fixed tissues and outcome in hepatocellular carcinoma
-
Hoshida Y, Villanueva A, Kobayashi M, Peix J, Chiang DY, Camargo A, Gupta S, Moore J, Wrobel MJ, Lerner J, Reich M, Chan JA, Glickman JN, Ikeda K, Hashimoto M, Watanabe G, Daidone MG, Roayaie S, Schwartz M, Thung S, Salvesen HB, Gabriel S, Mazzaferro V, Bruix J, Friedman SL, Kumada H, Llovet JM, Golub TR (2008) Gene expression in fixed tissues and outcome in hepatocellular carcinoma. N Engl J Med 359:1995-2004
-
(2008)
N Engl J Med
, vol.359
, pp. 1995-2004
-
-
Hoshida, Y.1
Villanueva, A.2
Kobayashi, M.3
Peix, J.4
Chiang, D.Y.5
Camargo, A.6
Gupta, S.7
Moore, J.8
Wrobel, M.J.9
Lerner, J.10
Reich, M.11
Chan, J.A.12
Glickman, J.N.13
Ikeda, K.14
Hashimoto, M.15
Watanabe, G.16
Daidone, M.G.17
Roayaie, S.18
Schwartz, M.19
Thung, S.20
Salvesen, H.B.21
Gabriel, S.22
Mazzaferro, V.23
Bruix, J.24
Friedman, S.L.25
Kumada, H.26
Llovet, J.M.27
Golub, T.R.28
more..
-
23
-
-
0024584166
-
Kappa B-specific DNA binding proteins: Role in the regulation of human interleukin-2 gene expression
-
Hoyos B, Ballard DW, Bohnlein E, Siekevitz M, Greene WC (1989) Kappa B-specific DNA binding proteins: role in the regulation of human interleukin-2 gene expression. Science 244:457-460 (Pubitemid 19127502)
-
(1989)
Science
, vol.244
, Issue.4903
, pp. 457-460
-
-
Hoyos, B.1
Ballard, D.W.2
Bohnlein, E.3
Siekevitz, M.4
Greene, W.C.5
-
24
-
-
76249087046
-
Disruption of TAK1 in hepatocytes causes hepatic injury, inflammation, fibrosis, and carcinogenesis
-
Inokuchi S, Aoyama T, Miura K, Osterreicher CH, Kodama Y, Miyai K, Akira S, Brenner DA, Seki E (2010) Disruption of TAK1 in hepatocytes causes hepatic injury, inflammation, fibrosis, and carcinogenesis. Proc Natl Acad Sci USA 107:844-849
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 844-849
-
-
Inokuchi, S.1
Aoyama, T.2
Miura, K.3
Osterreicher, C.H.4
Kodama, Y.5
Miyai, K.6
Akira, S.7
Brenner, D.A.8
Seki, E.9
-
25
-
-
0038352037
-
Involvement of NF-κB in the regulation of S100A6 gene expression in human hepatoblastoma cell line HepG2
-
DOI 10.1016/S0006-291X(03)01199-9
-
Joo JH, Kim JW, Lee Y, Yoon SY, Kim JH, Paik SG, Choe IS (2003) Involvement of NF-kappaB in the regulation of S100A6 gene expression in human hepatoblastoma cell line HepG2. Biochem Biophys Res Commun 307:274-280 (Pubitemid 36818865)
-
(2003)
Biochemical and Biophysical Research Communications
, vol.307
, Issue.2
, pp. 274-280
-
-
Joo, J.H.1
Kim, J.W.2
Lee, Y.3
Yoon, S.Y.4
Kim, J.H.5
Paik, S.-G.6
Choe, I.S.7
-
26
-
-
0034744949
-
NF-κB and cell-cycle regulation: The cyclin connection
-
DOI 10.1016/S1359-6101(00)00018-6, PII S1359610100000186
-
Joyce D, Albanese C, Steer J, Fu M, Bouzahzah B, Pestell RG (2001) NF-kappaB and cell-cycle regulation: the cyclin connection. Cytokine Growth Factor Rev 12:73-90 (Pubitemid 32294588)
-
(2001)
Cytokine and Growth Factor Reviews
, vol.12
, Issue.1
, pp. 73-90
-
-
Joyce, D.1
Albanese, C.2
Steer, J.3
Fu, M.4
Bouzahzah, B.5
Pestell, R.G.6
-
27
-
-
34547660308
-
Promiscuous mutations activate the noncanonical NF-κB pathway in multiple myeloma
-
DOI 10.1016/j.ccr.2007.07.003, PII S1535610807002024
-
Keats JJ, Fonseca R, Chesi M, Schop R, Baker A, Chng WJ, Van Wier S, Tiedemann R, Shi CX, Sebag M, Braggio E, Henry T, Zhu YX, Fogle H, Price-Troska T, Ahmann G, Mancini C, Brents LA, Kumar S, Greipp P, Dispenzieri A, Bryant B, Mulligan G, Bruhn L, Barrett M, Valdez R, Trent J, Stewart AK, Carpten J, Bergsagel PL (2007) Promiscuous mutations activate the noncanonical NF-kappaB pathway in multiple myeloma. Cancer Cell 12:131-144 (Pubitemid 47208626)
-
(2007)
Cancer Cell
, vol.12
, Issue.2
, pp. 131-144
-
-
Keats, J.J.1
Fonseca, R.2
Chesi, M.3
Schop, R.4
Baker, A.5
Chng, W.-J.6
Van Wier, S.7
Tiedemann, R.8
Shi, C.-X.9
Sebag, M.10
Braggio, E.11
Henry, T.12
Zhu, Y.-X.13
Fogle, H.14
Price-Troska, T.15
Ahmann, G.16
Mancini, C.17
Brents, L.A.18
Kumar, S.19
Greipp, P.20
Dispenzieri, A.21
Bryant, B.22
Mulligan, G.23
Bruhn, L.24
Barrett, M.25
Valdez, R.26
Trent, J.27
Stewart, A.K.28
Carpten, J.29
Bergsagel, P.L.30
more..
-
28
-
-
0036895749
-
TRAIL-mediated apoptosis requires NF-κB inhibition and the mitochondrial permeability transition in human hepatoma cells
-
DOI 10.1053/jhep.2002.36942
-
Kim YS, Schwabe RF, Qian T, Lemasters JJ, Brenner DA (2002) TRAIL-mediated apoptosis requires NF-kappaB inhibition and the mitochondrial permeability transition in human hepatoma cells. Hepatology 36:1498-1508 (Pubitemid 35403540)
-
(2002)
Hepatology
, vol.36
, Issue.6
, pp. 1498-1508
-
-
Kim, Y.-S.1
Schwabe, R.F.2
Qian, T.3
Lemasters, J.J.4
Brenner, D.A.5
-
29
-
-
60349107901
-
Targeted deletion of hepatocyte Ikkbeta confers growth advantages
-
Koch KS, Maeda S, He G, Karin M, Leffert HL (2009) Targeted deletion of hepatocyte Ikkbeta confers growth advantages. Biochem Biophys Res Commun 380:349-354
-
(2009)
Biochem Biophys Res Commun
, vol.380
, pp. 349-354
-
-
Koch, K.S.1
Maeda, S.2
He, G.3
Karin, M.4
Leffert, H.L.5
-
30
-
-
0034744033
-
NF-κB inducers upregulate cFLIP, a cycloheximide-sensitive inhibitor of death receptor signaling
-
DOI 10.1128/MCB.21.12.3964-3973.2001
-
Kreuz S, Siegmund D, Scheurich P, Wajant H (2001) NF-kappaB inducers upregulate cFLIP, a cycloheximide-sensitive inhibitor of death receptor signaling. Mol Cell Biol 21:3964-3973 (Pubitemid 32476458)
-
(2001)
Molecular and Cellular Biology
, vol.21
, Issue.12
, pp. 3964-3973
-
-
Kreuz, S.1
Siegmund, D.2
Scheurich, P.3
Wajant, H.4
-
31
-
-
17144449583
-
High susceptibility to bacterial infection, but no liver dysfunction, in mice compromised for hepatocyte NF-κB activation
-
DOI 10.1038/75057
-
Lavon I, Goldberg I, Amit S, Landsman L, Jung S, Tsuberi BZ, Barshack I, Kopolovic J, Galun E, Bujard H, Ben-Neriah Y (2000) High susceptibility to bacterial infection, but no liver dysfunction, in mice compromised for hepatocyte NF-kappaB activation. Nat Med 6:573-577 (Pubitemid 30305909)
-
(2000)
Nature Medicine
, vol.6
, Issue.5
, pp. 573-577
-
-
Lavon, I.1
Goldberg, I.2
Amit, S.3
Landsman, L.4
Jung, S.5
Tsuberi, B.-Z.6
Barshack, I.7
Kopolovic, J.8
Galun, E.9
Bujard, H.10
Ben-Neriah, Y.11
-
32
-
-
72849135966
-
The oncolytic activity of Newcastle disease virus NDV-HUJ on chemoresistant primary melanoma cells is dependent on the proapoptotic activity of the inhibitor of apoptosis protein Livin
-
Lazar I, Yaacov B, Shiloach T, Eliahoo E, Kadouri L, Lotem M, Perlman R, Zakay-Rones Z, Panet A, Ben-Yehuda D (2010) The oncolytic activity of Newcastle disease virus NDV-HUJ on chemoresistant primary melanoma cells is dependent on the proapoptotic activity of the inhibitor of apoptosis protein Livin. J Virol 84:639-646
-
(2010)
J Virol
, vol.84
, pp. 639-646
-
-
Lazar, I.1
Yaacov, B.2
Shiloach, T.3
Eliahoo, E.4
Kadouri, L.5
Lotem, M.6
Perlman, R.7
Zakay-Rones, Z.8
Panet, A.9
Ben-Yehuda, D.10
-
33
-
-
0033537739
-
Severe liver degeneration in mice lacking the IkappaB kinase 2 gene
-
Li Q, Van Antwerp D, Mercurio F, Lee KF, Verma IM (1999a) Severe liver degeneration in mice lacking the IkappaB kinase 2 gene. Science 284:321-325
-
(1999)
Science
, vol.284
, pp. 321-325
-
-
Li, Q.1
Van Antwerp, D.2
Mercurio, F.3
Lee, K.F.4
Verma, I.M.5
-
34
-
-
0033532386
-
The IKKβ subunit of IκB kinase (IKK) is essential for nuclear factor κB activation and prevention of apoptosis
-
DOI 10.1084/jem.189.11.1839
-
Li ZW, Chu W, Hu Y, Delhase M, Deerinck T, Ellisman M, Johnson R, Karin M (1999b) The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis. J Exp Med 189:1839-1845 (Pubitemid 29272700)
-
(1999)
Journal of Experimental Medicine
, vol.189
, Issue.11
, pp. 1839-1845
-
-
Li, Z.-W.1
Chu, W.2
Hu, Y.3
Delhase, M.4
Deerinck, T.5
Ellisman, M.6
Johnson, R.7
Karin, M.8
-
35
-
-
77952163228
-
The role of NF-kappaB in hepatitis B virus X protein-mediated upregulation of VEGF and MMPs
-
Liu LP, Liang HF, Chen XP, Zhang WG, Yang SL, Xu T, Ren L (2010) The role of NF-kappaB in hepatitis B virus X protein-mediated upregulation of VEGF and MMPs. Cancer Invest 28(5):443-451
-
(2010)
Cancer Invest
, vol.28
, Issue.5
, pp. 443-451
-
-
Liu, L.P.1
Liang, H.F.2
Chen, X.P.3
Zhang, W.G.4
Yang, S.L.5
Xu, T.6
Ren, L.7
-
36
-
-
33846839443
-
Deletion of NEMO/IKKγ in liver parenchymal cells causes steatohepatitis and hepatocellular carcinoma
-
DOI 10.1016/j.ccr.2006.12.016, PII S1535610807000207
-
Luedde T, Beraza N, Kotsikoris V, van Loo G, Nenci A, De Vos R, Roskams T, Trautwein C, Pasparakis M (2007) Deletion of NEMO/IKKgamma in liver parenchymal cells causes steatohepatitis and hepatocellular carcinoma. Cancer Cell 11:119-132 (Pubitemid 46209851)
-
(2007)
Cancer Cell
, vol.11
, Issue.2
, pp. 119-132
-
-
Luedde, T.1
Beraza, N.2
Kotsikoris, V.3
Van Loo, G.4
Nenci, A.5
De Vos, R.6
Roskams, T.7
Trautwein, C.8
Pasparakis, M.9
-
37
-
-
21244472975
-
IKKβ couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis
-
DOI 10.1016/j.cell.2005.04.014, PII S0092867405003946
-
Maeda S, Kamata H, Luo JL, Leffert H, Karin M (2005) IKKbeta couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis. Cell 121:977-990 (Pubitemid 40884391)
-
(2005)
Cell
, vol.121
, Issue.7
, pp. 977-990
-
-
Maeda, S.1
Kamata, H.2
Luo, J.-L.3
Leffert, H.4
Karin, M.5
-
38
-
-
0033634663
-
Female mice heterozygous for IKK gamma/NEMO deficiencies develop a dermatopathy similar to the human X-linked disorder incontinentia pigmenti
-
Makris C, Godfrey VL, Krahn-Senftleben G, Takahashi T, Roberts JL, Schwarz T, Feng L, Johnson RS, Karin M (2000) Female mice heterozygous for IKK gamma/NEMO deficiencies develop a dermatopathy similar to the human X-linked disorder incontinentia pigmenti. Mol Cell 5:969-979
-
(2000)
Mol Cell
, vol.5
, pp. 969-979
-
-
Makris, C.1
Godfrey, V.L.2
Krahn-Senftleben, G.3
Takahashi, T.4
Roberts, J.L.5
Schwarz, T.6
Feng, L.7
Johnson, R.S.8
Karin, M.9
-
39
-
-
70449109147
-
Requirement for NF-kappaB signalling in a mouse model of lung adenocarcinoma
-
Meylan E, Dooley AL, Feldser DM, Shen L, Turk E, Ouyang C, Jacks T (2009) Requirement for NF-kappaB signalling in a mouse model of lung adenocarcinoma. Nature 462:104-107
-
(2009)
Nature
, vol.462
, pp. 104-107
-
-
Meylan, E.1
Dooley, A.L.2
Feldser, D.M.3
Shen, L.4
Turk, E.5
Ouyang, C.6
Jacks, T.7
-
40
-
-
0034743199
-
NF-κB signals induce the expression of c-FLIP
-
DOI 10.1128/MCB.21.16.5299-5305.2001
-
Micheau O, Lens S, Gaide O, Alevizopoulos K, Tschopp J (2001) NF-kappaB signals induce the expression of c-FLIP. Mol Cell Biol 21:5299-5305 (Pubitemid 32702435)
-
(2001)
Molecular and Cellular Biology
, vol.21
, Issue.16
, pp. 5299-5305
-
-
Micheau, O.1
Lens, S.2
Gaide, O.3
Alevizopoulos, K.4
Tschopp, J.5
-
41
-
-
33748422079
-
Oncogene-induced cell senescence - Halting on the road to cancer
-
DOI 10.1056/NEJMra062285
-
Mooi WJ, Peeper DS (2006) Oncogene-induced cell senescence-halting on the road to cancer. N Engl J Med 355:1037-1046 (Pubitemid 44343547)
-
(2006)
New England Journal of Medicine
, vol.355
, Issue.10
, pp. 1037-1046
-
-
Mooi, W.J.1
Peeper, D.S.2
-
42
-
-
70350070334
-
S100A8 and S100A9 are novel nuclear factor kappa B target genes during malignant progression of murine and human liver carcinogenesis
-
Nemeth J, Stein I, Haag D, Riehl A, Longerich T, Horwitz E, Breuhahn K, Gebhardt C, Schirmacher P, Hahn M, Ben-Neriah Y, Pikarsky E, Angel P, Hess J (2009) S100A8 and S100A9 are novel nuclear factor kappa B target genes during malignant progression of murine and human liver carcinogenesis. Hepatology 50:1251-1262
-
(2009)
Hepatology
, vol.50
, pp. 1251-1262
-
-
Nemeth, J.1
Stein, I.2
Haag, D.3
Riehl, A.4
Longerich, T.5
Horwitz, E.6
Breuhahn, K.7
Gebhardt, C.8
Schirmacher, P.9
Hahn, M.10
Ben-Neriah, Y.11
Pikarsky, E.12
Angel, P.13
Hess, J.14
-
43
-
-
34047173496
-
Epithelial NEMO links innate immunity to chronic intestinal inflammation
-
DOI 10.1038/nature05698, PII NATURE05698
-
Nenci A, Becker C, Wullaert A, Gareus R, van Loo G, Danese S, Huth M, Nikolaev A, Neufert C, Madison B, Gumucio D, Neurath MF, Pasparakis M (2007) Epithelial NEMO links innate immunity to chronic intestinal inflammation. Nature 446:557-561 (Pubitemid 46514732)
-
(2007)
Nature
, vol.446
, Issue.7135
, pp. 557-561
-
-
Nenci, A.1
Becker, C.2
Wullaert, A.3
Gareus, R.4
Van Loo, G.5
Danese, S.6
Huth, M.7
Nikolaev, A.8
Neufert, C.9
Madison, B.10
Gumucio, D.11
Neurath, M.F.12
Pasparakis, M.13
-
44
-
-
37049004740
-
Expression of nuclear factor-kappaB family proteins in hepatocellular carcinomas
-
DOI 10.1159/000111116
-
O'Neil BH, Buzkova P, Farrah H, Kashatus D, Sanoff H, Goldberg RM, Baldwin AS, Funkhouser WK (2007) Expression of nuclear factor-kappaB family proteins in hepatocellular carcinomas. Oncology 72:97-104 (Pubitemid 350249136)
-
(2007)
Oncology
, vol.72
, Issue.1-2
, pp. 97-104
-
-
O'Neil, B.H.1
Buzkova, P.2
Farrah, H.3
Kashatus, D.4
Sanoff, H.5
Goldberg, R.M.6
Baldwin, A.S.7
Funkhouser, W.K.8
-
45
-
-
4644324186
-
NF-κB functions as a tumour promoter in inflammation-associated cancer
-
DOI 10.1038/nature02924
-
Pikarsky E, Porat RM, Stein I, Abramovitch R, Amit S, Kasem S, Gutkovich-Pyest E, Urieli-Shoval S, Galun E, Ben-Neriah Y (2004) NF-kappaB functions as a tumour promoter in inflammation-associated cancer. Nature 431:461-466 (Pubitemid 39329586)
-
(2004)
Nature
, vol.431
, Issue.7007
, pp. 461-466
-
-
Pikarsky, E.1
Porat, R.M.2
Stein, I.3
Abramovitch, R.4
Amit, S.5
Kasem, S.6
Gutkovich-Pyest, E.7
Uriell-Shoval, S.8
Galun, E.9
Ben-Neriah, Y.10
-
46
-
-
0033961219
-
NF-κB determines between apoptosis and proliferation in hepatocytes during liver regeneration
-
Plumpe J, Malek NP, Bock CT, Rakemann T, Manns MP, Trautwein C (2000) NF-kappaB determines between apoptosis and proliferation in hepatocytes during liver regeneration. Am J Physiol Gastrointest Liver Physiol 278:G173-G183 (Pubitemid 30108082)
-
(2000)
American Journal of Physiology - Gastrointestinal and Liver Physiology
, vol.278
, Issue.1
-
-
Plumpe, J.1
Malek, N.P.2
Bock, C.-T.3
Rakemann, T.4
Manns, M.P.5
Trautwein, C.6
-
47
-
-
33645457576
-
Constitutive activation of NF-kappaB in human hepatocellular carcinoma: Evidence of a cytoprotective role
-
Qiao L, Zhang H, Yu J, Francisco R, Dent P, Ebert MP, Rocken C, Farrell G (2006) Constitutive activation of NF-kappaB in human hepatocellular carcinoma: evidence of a cytoprotective role. Hum Gene Ther 17:280-290
-
(2006)
Hum Gene Ther
, vol.17
, pp. 280-290
-
-
Qiao, L.1
Zhang, H.2
Yu, J.3
Francisco, R.4
Dent, P.5
Ebert, M.P.6
Rocken, C.7
Farrell, G.8
-
48
-
-
0033596124
-
Aberrant rel/nfkb genes and activity in human cancer
-
Rayet B, Gelinas C (1999) Aberrant rel/nfkb genes and activity in human cancer. Oncogene 18:6938-6947
-
(1999)
Oncogene
, vol.18
, pp. 6938-6947
-
-
Rayet, B.1
Gelinas, C.2
-
49
-
-
0033873796
-
Prevention of hepatic apoptosis and embryonic lethality in ReIa/TNFR-1 double knockout mice
-
Rosenfeld ME, Prichard L, Shiojiri N, Fausto N (2000) Prevention of hepatic apoptosis and embryonic lethality in RelA/TNFR-1 double knockout mice. Am J Pathol 156:997-1007 (Pubitemid 30626957)
-
(2000)
American Journal of Pathology
, vol.156
, Issue.3
, pp. 997-1007
-
-
Rosenfeld, M.E.1
Prichard, L.2
Shiojiri, N.3
Fausto, N.4
-
50
-
-
0034175632
-
Severe liver degeneration and lack of NF-κB activation in NEMO/IKK γ- deficient mice
-
Rudolph D, Yeh WC, Wakeham A, Rudolph B, Nallainathan D, Potter J, Elia AJ, Mak TW (2000) Severe liver degeneration and lack of NF-kappaB activation in NEMO/IKKgammadeficient mice. Genes Dev 14:854-862 (Pubitemid 30215004)
-
(2000)
Genes and Development
, vol.14
, Issue.7
, pp. 854-862
-
-
Rudolph, D.1
Yeh, W.-C.2
Wakeham, A.3
Rudolph, B.4
Nallainathan, D.5
Potter, J.6
Elia, A.J.7
Mak, T.W.8
-
51
-
-
0029910845
-
Hepatocyte growth factor/scatter factor overexpression induces growth, abnormal development, and tumor formation in transgenic mouse livers
-
Sakata H, Takayama H, Sharp R, Rubin JS, Merlino G, LaRochelle WJ (1996) Hepatocyte growth factor/scatter factor overexpression induces growth, abnormal development, and tumor formation in transgenic mouse livers. Cell Growth Differ 7:1513-1523 (Pubitemid 26378346)
-
(1996)
Cell Growth and Differentiation
, vol.7
, Issue.11
, pp. 1513-1523
-
-
Sakata, H.1
Takayama, H.2
Sharp, R.3
Rubin, J.S.4
Merlino, G.5
LaRochelle, W.J.6
-
52
-
-
33746032571
-
Loss of hepatic NF-κB activity enhances chemical hepatocarcinogenesis through sustained c-Jun N-terminal kinase 1 activation
-
DOI 10.1073/pnas.0603499103
-
Sakurai T, Maeda S, Chang L, Karin M (2006) Loss of hepatic NF-kappa B activity enhances chemical hepatocarcinogenesis through sustained c-Jun. N-terminal kinase 1 activation. Proc Natl Acad Sci USA 103:10544-10551 (Pubitemid 44078014)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.28
, pp. 10544-10551
-
-
Sakurai, T.1
Maeda, S.2
Chang, L.3
Karin, M.4
-
53
-
-
0029793097
-
Inhibition of neoplastic development in the liver by hepatocyte growth factor in a transgenic mouse model
-
DOI 10.1073/pnas.93.18.9577
-
Santoni-Rugiu E, Preisegger KH, Kiss A, Audolfsson T, Shiota G, Schmidt EV, Thorgeirsson SS (1996) Inhibition of neoplastic development in the liver by hepatocyte growth factor in a transgenic mouse model. Proc Natl Acad Sci USA 93:9577-9582 (Pubitemid 26296650)
-
(1996)
Proceedings of the National Academy of Sciences of the United States of America
, vol.93
, Issue.18
, pp. 9577-9582
-
-
Santoni-Rugiu, E.1
Preisegger, K.H.2
Kiss, A.3
Audolfsson, T.4
Shiota, G.5
Schmidt, E.V.6
Thorgeirsson, S.S.7
-
55
-
-
77951605788
-
The Hox genes and their roles in oncogenesis
-
Shah N, Sukumar S (2010) The Hox genes and their roles in oncogenesis. Nat Rev Cancer 10:361-371
-
(2010)
Nat Rev Cancer
, vol.10
, pp. 361-371
-
-
Shah, N.1
Sukumar, S.2
-
56
-
-
49649113170
-
Expression of X-linked inhibitor-of-apoptosis protein in hepatocellular carcinoma promotes metastasis and tumor recurrence
-
Shi YH, Ding WX, Zhou J, He JY, Xu Y, Gambotto AA, Rabinowich H, Fan J, Yin XM (2008) Expression of X-linked inhibitor-of-apoptosis protein in hepatocellular carcinoma promotes metastasis and tumor recurrence. Hepatology 48:497-507
-
(2008)
Hepatology
, vol.48
, pp. 497-507
-
-
Shi, Y.H.1
Ding, W.X.2
Zhou, J.3
He, J.Y.4
Xu, Y.5
Gambotto, A.A.6
Rabinowich, H.7
Fan, J.8
Yin, X.M.9
-
57
-
-
0037457017
-
Interferon-α sensitizes human hepatoma cells to TRAIL-induced apoptosis through DR5 upregulation and NF-κB inactivation
-
DOI 10.1038/sj.onc.1206139
-
Shigeno M, Nakao K, Ichikawa T, Suzuki K, Kawakami A, Abiru S, Miyazoe S, Nakagawa Y, Ishikawa H, Hamasaki K, Nakata K, Ishii N, Eguchi K (2003) Interferon-alpha sensitizes human hepatoma cells to TRAIL-induced apoptosis through DR5 upregulation and NF-kappa B inactivation. Oncogene 22:1653-1662 (Pubitemid 36408180)
-
(2003)
Oncogene
, vol.22
, Issue.11
, pp. 1653-1662
-
-
Shigeno, M.1
Nakao, K.2
Ichikawa, T.3
Suzuki, K.4
Kawakami, A.5
Abiru, S.6
Miyazoe, S.7
Nakagawa, Y.8
Ishikawa, H.9
Hamasaki, K.10
Nakata, K.11
Ishii, N.12
Eguchi, K.13
-
58
-
-
0028970934
-
Characterization of double transgenic mice expressing hepatocye growth factor and transforming growth factor alpha
-
Shiota G, Kawasaki H, Nakamura T, Schmidt EV (1995) Characterization of double transgenic mice expressing hepatocye growth factor and transforming growth factor alpha. Res Commun Mol Pathol Pharmacol 90:17-24
-
(1995)
Res Commun Mol Pathol Pharmacol
, vol.90
, pp. 17-24
-
-
Shiota, G.1
Kawasaki, H.2
Nakamura, T.3
Schmidt, E.V.4
-
59
-
-
0027363563
-
Homozygous disruption of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease
-
DOI 10.1016/0092-8674(93)90380-9
-
Smit JJ, Schinkel AH, Oude Elferink RP, Groen AK, Wagenaar E, van Deemter L, Mol CA, Ottenhoff R, van der Lugt NM, van Roon MA et al (1993) Homozygous disruption of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease. Cell 75:451-462 (Pubitemid 23335071)
-
(1993)
Cell
, vol.75
, Issue.3
, pp. 451-462
-
-
Smit, J.J.M.1
Schinkel, A.H.2
Elferink, R.P.J.O.3
Groen, A.K.4
Wagenaar, E.5
Van Deemter, L.6
Mol, C.A.A.M.7
Ottenhoff, R.8
Van Der Lugt, N.M.T.9
Van Roon, M.A.10
Van Der Valk, M.A.11
Offerhaus, G.J.A.12
Berns, A.J.M.13
Borst, P.14
-
60
-
-
0032490670
-
Nuclear factor (NF)-κB-regulated X-chromosome-linked iap gene expression protects endothelial cells from tumor necrosis factor α-induced apoptosis
-
DOI 10.1084/jem.188.1.211
-
Stehlik C, de Martin R, Kumabashiri I, Schmid JA, Binder BR, Lipp J (1998) Nuclear factor (NF)-kappaB-regulated X-chromosome-linked iap gene expression protects endothelial cells from tumor necrosis factor alpha-induced apoptosis. J Exp Med 188:211-216 (Pubitemid 28328620)
-
(1998)
Journal of Experimental Medicine
, vol.188
, Issue.1
, pp. 211-216
-
-
Stehlik, C.1
De Martin, R.2
Kumabashiri, I.3
Schmid, J.A.4
Binder, B.R.5
Lipp, J.6
-
61
-
-
17544383005
-
Activation of nuclear factor κB in hepatitis C virus infection: Implications for pathogenesis and hepatocarcinogenesis
-
Tai DI, Tsai SL, Chen YM, Chuang YL, Peng CY, Sheen IS, Yeh CT, Chang KS, Huang SN, Kuo GC, Liaw YF (2000) Activation of nuclear factor kappaB in hepatitis C virus infection: implications for pathogenesis and hepatocarcinogenesis. Hepatology 31:656-664 (Pubitemid 30118634)
-
(2000)
Hepatology
, vol.31
, Issue.3
, pp. 656-664
-
-
Tai, D.-I.1
Tsai, S.-L.2
Chen, Y.-M.3
Chuang, Y.-L.4
Peng, C.-Y.5
Sheen, I.-S.6
Yeh, C.-T.7
Chang, K.S.S.8
Huang, S.-N.9
Kuo, G.C.10
Liaw, Y.-F.11
-
62
-
-
35448964238
-
Loss of hepatocyte growth factor/c-Met signaling pathway accelerates early stages of N-nitrosodiethylamine-induced hepatocarcinogenesis
-
DOI 10.1158/0008-5472.CAN-07-1905
-
Takami T, Kaposi-Novak P, Uchida K, Gomez-Quiroz LE, Conner EA, Factor VM, Thorgeirsson SS (2007) Loss of hepatocyte growth factor/c-Met signaling pathway accelerates early stages of N-nitrosodiethylamine induced hepatocarcinogenesis. Cancer Res 67:9844-9851 (Pubitemid 47621232)
-
(2007)
Cancer Research
, vol.67
, Issue.20
, pp. 9844-9851
-
-
Takami, T.1
Kaposi-Novak, P.2
Uchida, K.3
Gomez-Quiroz, L.E.4
Conner, E.A.5
Factor, V.M.6
Thorgeirsson, S.S.7
-
63
-
-
33746555367
-
LA2 mice
-
DOI 10.1038/ng1836, PII NG1836
-
To MD, Perez-Losada J, Mao JH, Hsu J, Jacks T, Balmain A (2006) A functional switch from lung cancer resistance to susceptibility at the Pas1 locus in Kras2LA2 mice. Nat Genet 38:926-930 (Pubitemid 44141662)
-
(2006)
Nature Genetics
, vol.38
, Issue.8
, pp. 926-930
-
-
To, M.D.1
Perez-Losada, J.2
Mao, J.-H.3
Hsu, J.4
Jacks, T.5
Balmain, A.6
-
64
-
-
0032827012
-
Induction of Bcl-x(L) expression by human T-cell leukemia virus type 1 tax through NF-κB in apoptosis-resistant T-cell transfectants with Tax
-
Tsukahara T, Kannagi M, Ohashi T, Kato H, Arai M, Nunez G, Iwanaga Y, Yamamoto N, Ohtani K, Nakamura M, Fujii M (1999) Induction of Bcl-x (L) expression by human T-cell leukemia virus type 1 Tax through NF-kappaB in apoptosis-resistant T-cell transfectants with Tax. J Virol 73:7981-7987 (Pubitemid 29441656)
-
(1999)
Journal of Virology
, vol.73
, Issue.10
, pp. 7981-7987
-
-
Tsukahara, T.1
Kannagi, M.2
Ohashi, T.3
Kato, H.4
Arai, M.5
Nunez, G.6
Iwanaga, Y.7
Yamamoto, N.8
Ohtani, K.9
Nakamura, M.10
Fujii, M.11
-
65
-
-
47849120873
-
Contradictory functions of NF-kappaB in liver physiology and cancer
-
Vainer GW, Pikarsky E, Ben-Neriah Y (2008) Contradictory functions of NF-kappaB in liver physiology and cancer. Cancer Lett 267:182-188
-
(2008)
Cancer Lett
, vol.267
, pp. 182-188
-
-
Vainer, G.W.1
Pikarsky, E.2
Ben-Neriah, Y.3
-
66
-
-
0033565763
-
Squamous cell carcinomas and increased apoptosis in skin with inhibited Rel/nuclear factor-κB signaling
-
van Hogerlinden M, Rozell BL, Ahrlund-Richter L, Toftgard R (1999) Squamous cell carcinomas and increased apoptosis in skin with inhibited Rel/nuclear factor-kappaB signaling. Cancer Res 59:3299-3303 (Pubitemid 29334479)
-
(1999)
Cancer Research
, vol.59
, Issue.14
, pp. 3299-3303
-
-
Van Hogerlinden, M.1
Rozell, B.L.2
Ahrlund-Richter, L.3
Toftgard, R.4
-
67
-
-
0037173722
-
Inhibition of Rel/Nuclear Factor-kappaB signaling in skin results in defective DNA damage-induced cell cycle arrest and Ha-ras-and p53-independent tumor development
-
van Hogerlinden M, Auer G, Toftgard R (2002) Inhibition of Rel/Nuclear Factor-kappaB signaling in skin results in defective DNA damage-induced cell cycle arrest and Ha-ras-and p53-independent tumor development. Oncogene 21:4969-4977
-
(2002)
Oncogene
, vol.21
, pp. 4969-4977
-
-
Van Hogerlinden, M.1
Auer, G.2
Toftgard, R.3
-
68
-
-
0032508414
-
NF-kappaB antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation
-
Wang CY, Mayo MW, Korneluk RG, Goeddel DV, Baldwin AS Jr (1998) NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation. Science 281:1680-1683
-
(1998)
Science
, vol.281
, pp. 1680-1683
-
-
Wang, C.Y.1
Mayo, M.W.2
Korneluk, R.G.3
Goeddel, D.V.4
Baldwin Jr., A.S.5
-
69
-
-
0035947770
-
Activation of the Met receptor by cell attachment induces and sustains hepatocellular carcinomas in transgenic mice
-
Wang R, Ferrell LD, Faouzi S, Maher JJ, Bishop JM (2001) Activation of the Met receptor by cell attachment induces and sustains hepatocellular carcinomas in transgenic mice. J Cell Biol 153:1023-1034
-
(2001)
J Cell Biol
, vol.153
, pp. 1023-1034
-
-
Wang, R.1
Ferrell, L.D.2
Faouzi, S.3
Maher, J.J.4
Bishop, J.M.5
-
70
-
-
56349110991
-
Nuclear-factor-kappaB (NF-kappaB) and radical oxygen species play contrary roles in transforming growth factor-beta1 (TGF-beta1)-induced apoptosis in hepatocellular carcinoma (HCC) cells
-
Wang F, Kaur S, Cavin LG, Arsura M (2008) Nuclear-factor-kappaB (NF-kappaB) and radical oxygen species play contrary roles in transforming growth factor-beta1 (TGF-beta1)-induced apoptosis in hepatocellular carcinoma (HCC) cells. Biochem Biophys Res Commun 377:1107-1112
-
(2008)
Biochem Biophys Res Commun
, vol.377
, pp. 1107-1112
-
-
Wang, F.1
Kaur, S.2
Cavin, L.G.3
Arsura, M.4
-
71
-
-
70350054798
-
Role of microRNA-155 at early stages of hepatocarcinogenesis induced by choline-deficient and amino acid-defined diet in C57BL/6 mice
-
Wang B, Majumder S, Nuovo G, Kutay H, Volinia S, Patel T, Schmittgen TD, Croce C, Ghoshal K, Jacob ST (2009) Role of microRNA-155 at early stages of hepatocarcinogenesis induced by choline-deficient and amino acid-defined diet in C57BL/6 mice. Hepatology 50:1152-1161
-
(2009)
Hepatology
, vol.50
, pp. 1152-1161
-
-
Wang, B.1
Majumder, S.2
Nuovo, G.3
Kutay, H.4
Volinia, S.5
Patel, T.6
Schmittgen, T.D.7
Croce, C.8
Ghoshal, K.9
Jacob, S.T.10
-
72
-
-
0034774463
-
Mitochondrially associated hepatitis B virus X protein constitutively activates transcription factors STAT-3 and NF-κB via oxidative stress
-
DOI 10.1128/MCB.21.22.7721-7730.2001
-
Waris G, Huh KW, Siddiqui A (2001) Mitochondrially associated hepatitis B virus X protein constitutively activates transcription factors STAT-3 and NF-kappa B via oxidative stress. Mol Cell Biol 21:7721-7730 (Pubitemid 32988782)
-
(2001)
Molecular and Cellular Biology
, vol.21
, Issue.22
, pp. 7721-7730
-
-
Waris, G.1
Huh, K.-W.2
Siddiqui, A.3
-
73
-
-
60549116315
-
Hepatocyte-specific activation of NF-kappaB does not aggravate chemical hepatocarcinogenesis in transgenic mice
-
Yau TO, Chan CF, Gee-San Lam S, Cheung OF, Ching YP, Jin DY, Sham MH, Ng IO (2009) Hepatocyte-specific activation of NF-kappaB does not aggravate chemical hepatocarcinogenesis in transgenic mice. J Pathol 217:353-361
-
(2009)
J Pathol
, vol.217
, pp. 353-361
-
-
Yau, T.O.1
Chan, C.F.2
Gee-San Lam, S.3
Cheung, O.F.4
Ching, Y.P.5
Jin, D.Y.6
Sham, M.H.7
Ng, I.O.8
-
74
-
-
75749132016
-
USP10 regulates p53 localization and stability by deubiquitinating p53
-
Yuan J, Luo K, Zhang L, Cheville JC, Lou Z (2010) USP10 regulates p53 localization and stability by deubiquitinating p53. Cell 140:384-396
-
(2010)
Cell
, vol.140
, pp. 384-396
-
-
Yuan, J.1
Luo, K.2
Zhang, L.3
Cheville, J.C.4
Lou, Z.5
-
75
-
-
17944369909
-
Wildtype Kras2 can inhibit lung carcinogenesis in mice
-
DOI 10.1038/ng721
-
Zhang Z, Wang Y, Vikis HG, Johnson L, Liu G, Li J, Anderson MW, Sills RC, Hong HL, Devereux TR, Jacks T, Guan KL, You M (2001) Wildtype Kras2 can inhibit lung carcinogenesis in mice. Nat Genet 29:25-33 (Pubitemid 32801804)
-
(2001)
Nature Genetics
, vol.29
, Issue.1
, pp. 25-33
-
-
Zhang, Z.1
Wang, Y.2
Vikis, H.G.3
Johnson, L.4
Liu, G.5
Li, J.6
Anderson, M.W.7
Sills, R.C.8
Hong, H.L.9
Devereux, T.R.10
Jacks, T.11
Guan, K.-L.12
You, M.13
-
76
-
-
68949184660
-
Up-regulated microRNA-143 transcribed by nuclear factor kappa B enhances hepatocarcinoma metastasis by repressing fibronectin expression
-
Zhang X, Liu S, Hu T, Liu S, He Y, Sun S (2009) Up-regulated microRNA-143 transcribed by nuclear factor kappa B enhances hepatocarcinoma metastasis by repressing fibronectin expression. Hepatology 50:490-499
-
(2009)
Hepatology
, vol.50
, pp. 490-499
-
-
Zhang, X.1
Liu, S.2
Hu, T.3
Liu, S.4
He, Y.5
Sun, S.6
|