-
2
-
-
34247251277
-
Isoform specificity of protein kinase Cs in synaptic plasticity
-
Sossin WS (2007) Isoform specificity of protein kinase Cs in synaptic plasticity. Learn Mem 14:236-246
-
(2007)
Learn Mem
, vol.14
, pp. 236-246
-
-
Sossin, W.S.1
-
4
-
-
1942438618
-
Epidermal keratinocytes: Regulation of multiple cell phenotypes by multiple protein kinase C isoforms
-
Denning MF (2004) Epidermal keratinocytes: regulation of multiple cell phenotypes by multiple protein kinase C isoforms. Int J Biochem Cell Biol 36:1141-1146
-
(2004)
Int J Biochem Cell Biol
, vol.36
, pp. 1141-1146
-
-
Denning, M.F.1
-
5
-
-
0037710311
-
The isoform-specific regulation of apoptosis by protein kinase C
-
Gutcher I, Webb PR, Anderson NG (2003) The isoform-specific regulation of apoptosis by protein kinase C. Cell Mol Life Sci 60:1061-1070
-
(2003)
Cell Mol Life Sci
, vol.60
, pp. 1061-1070
-
-
Gutcher, I.1
Webb, P.R.2
Anderson, N.G.3
-
6
-
-
3042647350
-
Protein kinase C and prostate carcinogenesis: Targeting the cell cycle and apoptotic mechanisms
-
Gavrielides MV, Frijhoff AF, Conti CJ, Kazanietz MG (2004) Protein kinase C and prostate carcinogenesis: targeting the cell cycle and apoptotic mechanisms. Curr Drug Targets 5:431-443
-
(2004)
Curr Drug Targets
, vol.5
, pp. 431-443
-
-
Gavrielides, M.V.1
Frijhoff, A.F.2
Conti, C.J.3
Kazanietz, M.G.4
-
7
-
-
69049118117
-
PKC differentially translocates during spaced and massed training in Aplysia
-
Farah CA, Weatherill D, Dunn TW, Sossin WS (2009) PKC differentially translocates during spaced and massed training in Aplysia. J Neurosci 29:10281-10286
-
(2009)
J Neurosci
, vol.29
, pp. 10281-10286
-
-
Farah, C.A.1
Weatherill, D.2
Dunn, T.W.3
Sossin, W.S.4
-
8
-
-
33746852464
-
Protein kinase C regulatory domains: The art of decoding many different signals in membranes
-
Corbalan-Garcia S, Gomez-Fernandez JC (2006) Protein kinase C regulatory domains: the art of decoding many different signals in membranes. Biochim Biophys Acta 1761:633-654
-
(2006)
Biochim Biophys Acta
, vol.1761
, pp. 633-654
-
-
Corbalan-Garcia, S.1
Gomez-Fernandez, J.C.2
-
9
-
-
0023555557
-
Protein kinase C contains a pseudosubstrate prototope in its regulatory domain
-
House C, Kemp BE (1987) Protein kinase C contains a pseudosubstrate prototope in its regulatory domain. Science 238:1726-1728
-
(1987)
Science
, vol.238
, pp. 1726-1728
-
-
House, C.1
Kemp, B.E.2
-
10
-
-
0024469531
-
Complete activation of protein kinase C by an antipeptide antibody directed against the pseudosubstrate prototope
-
Makowske M, Rosen OM (1989) Complete activation of protein kinase C by an antipeptide antibody directed against the pseudosubstrate prototope. J Biol Chem 264:16155-16159
-
(1989)
J Biol Chem
, vol.264
, pp. 16155-16159
-
-
Makowske, M.1
Rosen, O.M.2
-
11
-
-
30044437467
-
Specific translocation of protein kinase Calpha to the plasma membrane requires both Ca2+ and PIP2 recognition by its C2 domain
-
Evans JH, Murray D, Leslie CC, Falke JJ (2006) Specific translocation of protein kinase Calpha to the plasma membrane requires both Ca2+ and PIP2 recognition by its C2 domain. Mol Biol Cell 17:56-66
-
(2006)
Mol Biol Cell
, vol.17
, pp. 56-66
-
-
Evans, J.H.1
Murray, D.2
Leslie, C.C.3
Falke, J.J.4
-
12
-
-
58149169884
-
Spatiotemporal dynamics of lipid signaling: Protein kinase C as a paradigm
-
Gallegos LL, Newton AC (2008) Spatiotemporal dynamics of lipid signaling: protein kinase C as a paradigm. IUBMB Life 60:782-789
-
(2008)
IUBMB Life
, vol.60
, pp. 782-789
-
-
Gallegos, L.L.1
Newton, A.C.2
-
13
-
-
33748698501
-
The C2 domain of PKCalpha is a Ca2+ -dependent PtdIns (4,5)P2 sensing domain: A new insight into an old pathway
-
Sanchez-Bautista S, Marin-Vicente C, Gomez-Fernandez JC, Corbalan-Garcia S (2006) The C2 domain of PKCalpha is a Ca2+ -dependent PtdIns(4,5)P2 sensing domain: a new insight into an old pathway. J Mol Biol 362:901-914
-
(2006)
J Mol Biol 362
, pp. 901-914
-
-
Sanchez-Bautista, S.1
Marin-Vicente, C.2
Gomez-Fernandez, J.C.3
Corbalan-Garcia, S.4
-
14
-
-
0027276016
-
Ca2+ -independent protein kinase Cs contain an amino-terminal domain similar to the C2 consensus sequence
-
Sossin WS, Schwartz JH (1993) Ca2+ -independent protein kinase Cs contain an amino-terminal domain similar to the C2 consensus sequence. Trends Biochem Sci 18:207-208
-
(1993)
Trends Biochem Sci
, vol.18
, pp. 207-208
-
-
Sossin, W.S.1
Schwartz, J.H.2
-
15
-
-
17444403210
-
The C2 domain of PKCdelta is a phosphotyrosine binding domain
-
Benes CH, Wu N, Elia AE, Dharia T, Cantley LC, Soltoff SP (2005) The C2 domain of PKCdelta is a phosphotyrosine binding domain. Cell 121:271-280
-
(2005)
Cell
, vol.121
, pp. 271-280
-
-
Benes, C.H.1
Wu, N.2
Elia, A.E.3
Dharia, T.4
Cantley, L.C.5
Soltoff, S.P.6
-
16
-
-
0034328882
-
The atypical protein kinase Cs. Functional specificity mediated by specific protein adapters
-
Moscat J, Diaz-Meco MT (2000) The atypical protein kinase Cs. Functional specificity mediated by specific protein adapters. EMBO Rep 1:399-403
-
(2000)
EMBO Rep
, vol.1
, pp. 399-403
-
-
Moscat, J.1
Diaz-Meco, M.T.2
-
17
-
-
0042346345
-
Cell polarity: The ups and downs of the Par6/aPKC complex
-
Henrique D, Schweisguth F (2003) Cell polarity: the ups and downs of the Par6/aPKC complex. Curr Opin Genet Dev 13:341-350
-
(2003)
Curr Opin Genet Dev
, vol.13
, pp. 341-350
-
-
Henrique, D.1
Schweisguth, F.2
-
18
-
-
3843129678
-
Solution structure of atypical protein kinase CPB1 domain and its mode of interaction with ZIP/p62 and MEK5
-
Hirano Y, Yoshinaga S, Ogura K, Yokochi M, Noda Y, Sumimoto H, Inagaki F (2004) Solution structure of atypical protein kinase CPB1 domain and its mode of interaction with ZIP/p62 and MEK5. J Biol Chem 279:31883-31890
-
(2004)
J Biol Chem
, vol.279
, pp. 31883-31890
-
-
Hirano, Y.1
Yoshinaga, S.2
Ogura, K.3
Yokochi, M.4
Noda, Y.5
Sumimoto, H.6
Inagaki, F.7
-
19
-
-
0027480323
-
Characterization of two isoforms of protein kinase C in the nervous system of Aplysia californica
-
Sossin WS, Diaz AR, Schwartz JH (1993) Characterization of two isoforms of protein kinase C in the nervous system of Aplysia californica. J Biol Chem 268:5763-5768
-
(1993)
J Biol Chem
, vol.268
, pp. 5763-5768
-
-
Sossin, W.S.1
Diaz, A.R.2
Schwartz, J.H.3
-
20
-
-
41449083833
-
Cloning and characterization of protein kinase C (PKC) Apl III, a homologue of atypical PKCs in Aplysia
-
Bougie J, Lim T, Ferraro G, Manjunath V, Scott D, Sossin WS (2006) Cloning and characterization of protein kinase C (PKC) Apl III, a homologue of atypical PKCs in Aplysia. Soc Neurosci Abstr 32:669-610
-
(2006)
Soc Neurosci Abstr
, vol.32
, pp. 669-610
-
-
Bougie, J.1
Lim, T.2
Ferraro, G.3
Manjunath, V.4
Scott, D.5
Sossin, W.S.6
-
21
-
-
0030467967
-
The C2 domain calcium-binding motif: Structural and functional diversity
-
Nalefski EA, Falke JJ (1996) The C2 domain calcium-binding motif: structural and functional diversity. Protein Sci 5:2375-2390
-
(1996)
Protein Sci
, vol.5
, pp. 2375-2390
-
-
Nalefski, E.A.1
Falke, J.J.2
-
22
-
-
40849104855
-
A phylogenomic investigation into the origin of metazoa
-
Ruiz-Trillo I, Roger AJ, Burger G, Gray MW, Lang BF (2008) A phylogenomic investigation into the origin of metazoa. Mol Biol Evol 25:664-672
-
(2008)
Mol Biol Evol
, vol.25
, pp. 664-672
-
-
Ruiz-Trillo, I.1
Roger, A.J.2
Burger, G.3
Gray, M.W.4
Lang, B.F.5
-
23
-
-
77957866592
-
Identification of novel families and classifi cation of the C2 domain superfamily elucidate the origin and evolution of membrane targeting activities in eukaryotes
-
Zhang D, Aravind L (2010) Identification of novel families and classifi cation of the C2 domain superfamily elucidate the origin and evolution of membrane targeting activities in eukaryotes. Gene 469:18-30
-
(2010)
Gene
, vol.469
, pp. 18-30
-
-
Zhang, D.1
Aravind, L.2
-
24
-
-
66149130348
-
Structural and mechanistic insights into the association of PKCalpha-C2 domain to PtdIns (4,5)P2
-
Guerrero-Valero M, Ferrer-Orta C, Querol-Audi J, Marin-Vicente C, Fita I, Gomez-Fernandez JC, Verdaguer N, Corbalan-Garcia S (2009) Structural and mechanistic insights into the association of PKCalpha-C2 domain to PtdIns(4,5)P2. Proc Natl Acad Sci USA 106:6603-6607
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 6603-6607
-
-
Guerrero-Valero, M.1
Ferrer-Orta, C.2
Querol-Audi, J.3
Marin-Vicente, C.4
Fita, I.5
Gomez-Fernandez, J.C.6
Verdaguer, N.7
Corbalan-Garcia, S.8
-
25
-
-
0035943428
-
Structure of the C2 domain from novel protein kinase Cepsilon. A membrane binding model for Ca(2+)-independent C2 domains
-
Ochoa WF, Garcia-Garcia J, Fita I, Corbalan-Garcia S, Verdaguer N, Gomez-Fernandez JC (2001) Structure of the C2 domain from novel protein kinase Cepsilon. A membrane binding model for Ca(2+)-independent C2 domains. J Mol Biol 311:837-849
-
(2001)
J Mol Biol
, vol.311
, pp. 837-849
-
-
Ochoa, W.F.1
Garcia-Garcia, J.2
Fita, I.3
Corbalan-Garcia, S.4
Verdaguer, N.5
Gomez-Fernandez, J.C.6
-
26
-
-
0024412493
-
The protein kinase C family: Heterogeneity and its implications
-
Kikkawa U, Kishimoto A, Nishizuka Y (1989) The protein kinase C family: heterogeneity and its implications. Annu Rev Biochem 58:31-44
-
(1989)
Annu Rev Biochem
, vol.58
, pp. 31-44
-
-
Kikkawa, U.1
Kishimoto, A.2
Nishizuka, Y.3
-
27
-
-
0023764824
-
The molecular heterogeneity of protein kinase C and its implications for cellular regulation
-
Nishizuka Y (1988) The molecular heterogeneity of protein kinase C and its implications for cellular regulation. Nature 334:661-665
-
(1988)
Nature
, vol.334
, pp. 661-665
-
-
Nishizuka, Y.1
-
28
-
-
0025939414
-
Cloning and characterization of Ca(2+)-dependent and Ca(2+)-independent PKCs expressed in Aplysia sensory cells
-
Kruger KE, Sossin WS, Sacktor TC, Bergold PJ, Beushausen S, Schwartz JH (1991) Cloning and characterization of Ca(2+)-dependent and Ca(2+)-independent PKCs expressed in Aplysia sensory cells. J Neurosci 11:2303-2313
-
(1991)
J Neurosci
, vol.11
, pp. 2303-2313
-
-
Kruger, K.E.1
Sossin, W.S.2
Sacktor, T.C.3
Bergold, P.J.4
Beushausen, S.5
Schwartz, J.H.6
-
29
-
-
0032533457
-
Structure of the protein kinase Cbeta phospholipid-binding C2 domain complexed with Ca2+
-
Sutton RB, Sprang SR (1998) Structure of the protein kinase Cbeta phospholipid-binding C2 domain complexed with Ca2+ . Structure 6:1395-1405
-
(1998)
Structure
, vol.6
, pp. 1395-1405
-
-
Sutton, R.B.1
Sprang, S.R.2
-
30
-
-
0029666292
-
Bipartite Ca2+ -binding motif in C2 domains of synaptotagmin and protein kinase C
-
Shao X, Davletov BA, Sutton RB, Sudhof TC, Rizo J (1996) Bipartite Ca2+ -binding motif in C2 domains of synaptotagmin and protein kinase C. Science 273:248-251
-
(1996)
Science
, vol.273
, pp. 248-251
-
-
Shao, X.1
Davletov, B.A.2
Sutton, R.B.3
Sudhof, T.C.4
Rizo, J.5
-
31
-
-
0030933176
-
A ternary metal binding site in the C2 domain of phosphoinositide- specific phospholipase C-delta1
-
Essen LO, Perisic O, Lynch DE, Katan M, Williams RL (1997) A ternary metal binding site in the C2 domain of phosphoinositide-specific phospholipase C-delta1. Biochemistry 36:2753-2762
-
(1997)
Biochemistry
, vol.36
, pp. 2753-2762
-
-
Essen, L.O.1
Perisic, O.2
Lynch, D.E.3
Katan, M.4
Williams, R.L.5
-
32
-
-
0033571223
-
Ca(2+) bridges the C2 membrane-binding domain of protein kinase Calpha directly to phosphatidylserine
-
Verdaguer N, Corbalan-Garcia S, Ochoa WF, Fita I, Gomez-Fernandez JC (1999) Ca(2+) bridges the C2 membrane-binding domain of protein kinase Calpha directly to phosphatidylserine. EMBO J 18:6329-6338
-
(1999)
EMBO J
, vol.18
, pp. 6329-6338
-
-
Verdaguer, N.1
Corbalan-Garcia, S.2
Ochoa, W.F.3
Fita, I.4
Gomez-Fernandez, J.C.5
-
33
-
-
0036297772
-
Additional binding sites for anionic phospholipids and calcium ions in the crystal structures of complexes of the C2 domain of protein kinase calpha
-
Ochoa WF, Corbalan-Garcia S, Eritja R, Rodriguez-Alfaro JA, Gomez-Fernandez JC, Fita I, Verdaguer N (2002) Additional binding sites for anionic phospholipids and calcium ions in the crystal structures of complexes of the C2 domain of protein kinase calpha. J Mol Biol 320:277-291
-
(2002)
J Mol Biol
, vol.320
, pp. 277-291
-
-
Ochoa, W.F.1
Corbalan-Garcia, S.2
Eritja, R.3
Rodriguez-Alfaro, J.A.4
Gomez-Fernandez, J.C.5
Fita, I.6
Verdaguer, N.7
-
34
-
-
0035818442
-
Membrane binding kinetics of protein kinase C betaII mediated by the C2 domain
-
Nalefski EA, Newton AC (2001) Membrane binding kinetics of protein kinase C betaII mediated by the C2 domain. Biochemistry 40:13216-13229
-
(2001)
Biochemistry
, vol.40
, pp. 13216-13229
-
-
Nalefski, E.A.1
Newton, A.C.2
-
35
-
-
33748769511
-
Structure of human protein kinase C eta (PKCeta) C2 domain and Identification of phosphorylation sites
-
Littler DR, Walker JR, She YM, Finerty PJ Jr, Newman EM, Dhe-Paganon S (2006) Structure of human protein kinase C eta (PKCeta) C2 domain and Identification of phosphorylation sites. Biochem Biophys Res Commun 349:1182-1189
-
(2006)
Biochem Biophys Res Commun
, vol.349
, pp. 1182-1189
-
-
Littler, D.R.1
Walker, J.R.2
She, Y.M.3
Finerty Jr., P.J.4
Newman, E.M.5
Dhe-Paganon, S.6
-
36
-
-
0032528071
-
Crystal structure of the C2 domain from protein kinase C-delta
-
Pappa H, Murray-Rust J, Dekker LV, Parker PJ, McDonald NQ (1998) Crystal structure of the C2 domain from protein kinase C-delta. Structure 6:885-894
-
(1998)
Structure
, vol.6
, pp. 885-894
-
-
Pappa, H.1
Murray-Rust, J.2
Dekker, L.V.3
Parker, P.J.4
McDonald, N.Q.5
-
37
-
-
0028596158
-
An alternative to SH2 domains for binding tyrosinephosphorylated proteins
-
Kavanaugh WM, Williams LT (1994) An alternative to SH2 domains for binding tyrosinephosphorylated proteins. Science 266:1862-1865
-
(1994)
Science
, vol.266
, pp. 1862-1865
-
-
Kavanaugh, W.M.1
Williams, L.T.2
-
38
-
-
17444424607
-
C2 can do it, too
-
Sondermann H, Kuriyan J (2005) C2 can do it, too. Cell 121:158-160
-
(2005)
Cell
, vol.121
, pp. 158-160
-
-
Sondermann, H.1
Kuriyan, J.2
-
39
-
-
0022977712
-
A noncatalytic domain conserved among cytoplasmic protein-tyrosine kinases modifi es the kinase function and transforming activity of Fujinami sarcoma virus P130gag-fps
-
Sadowski I, Stone JC, Pawson T (1986) A noncatalytic domain conserved among cytoplasmic protein-tyrosine kinases modifi es the kinase function and transforming activity of Fujinami sarcoma virus P130gag-fps. Mol Cell Biol 6:4396-4408
-
(1986)
Mol Cell Biol
, vol.6
, pp. 4396-4408
-
-
Sadowski, I.1
Stone, J.C.2
Pawson, T.3
-
40
-
-
0035413601
-
Protein kinase C: Structural and spatial regulation by phosphorylation, cofactors, and macromolecular interactions
-
Newton AC (2001) Protein kinase C: structural and spatial regulation by phosphorylation, cofactors, and macromolecular interactions. Chem Rev 101:2353-2364
-
(2001)
Chem Rev
, vol.101
, pp. 2353-2364
-
-
Newton, A.C.1
-
41
-
-
54449098958
-
Differential roles of phosphatidylserine, PtdIns (4,5)P2, and PtdIns(3,4,5)P3 in plasma membrane targeting of C2 domains. Molecular dynamics simulation, membrane binding, and cell translocation studies of the PKCalpha C2 domain
-
Manna D, Bhardwaj N, Vora MS, Stahelin RV, Lu H, Cho W (2008) Differential roles of phosphatidylserine, PtdIns(4,5)P2, and PtdIns(3,4,5)P3 in plasma membrane targeting of C2 domains. Molecular dynamics simulation, membrane binding, and cell translocation studies of the PKCalpha C2 domain. J Biol Chem 283:26047-26058
-
(2008)
J Biol Chem
, vol.283
, pp. 26047-26058
-
-
Manna, D.1
Bhardwaj, N.2
Vora, M.S.3
Stahelin, R.V.4
Lu, H.5
Cho, W.6
-
42
-
-
19644373567
-
The ATP-dependent membrane localization of protein kinase Calpha is regulated by Ca2+ influx and phosphatidylinositol 4,5-bisphosphate in differentiated PC12 cells
-
Marin-Vicente C, Gomez-Fernandez JC, Corbalan-Garcia S (2005) The ATP-dependent membrane localization of protein kinase Calpha is regulated by Ca2+ influx and phosphatidylinositol 4,5-bisphosphate in differentiated PC12 cells. Mol Biol Cell 16:2848-2861
-
(2005)
Mol Biol Cell
, vol.16
, pp. 2848-2861
-
-
Marin-Vicente, C.1
Gomez-Fernandez, J.C.2
Corbalan-Garcia, S.3
-
43
-
-
40849111154
-
The PtdIns (4,5)P2 ligand itself influences the localization of PKCalpha in the plasma membrane of intact living cells
-
Marin-Vicente C, Nicolas FE, Gomez-Fernandez JC, Corbalan-Garcia S (2008) The PtdIns(4,5)P2 ligand itself influences the localization of PKCalpha in the plasma membrane of intact living cells. J Mol Biol 377:1038-1052
-
(2008)
J Mol Biol
, vol.377
, pp. 1038-1052
-
-
Marin-Vicente, C.1
Nicolas, F.E.2
Gomez-Fernandez, J.C.3
Corbalan-Garcia, S.4
-
44
-
-
33748255729
-
Isoform specificity of PKC translocation in living Aplysia sensory neurons and a role for Ca2+ -dependent PKC APL i in the induction of intermediate-term facilitation
-
Zhao Y, Leal K, Abi-Farah C, Martin KC, Sossin WS, Klein M (2006) Isoform specificity of PKC translocation in living Aplysia sensory neurons and a role for Ca2+ -dependent PKC APL I in the induction of intermediate-term facilitation. J Neurosci 26:8847-8856
-
(2006)
J Neurosci
, vol.26
, pp. 8847-8856
-
-
Zhao, Y.1
Leal, K.2
Abi-Farah, C.3
Martin, K.C.4
Sossin, W.S.5
Klein, M.6
-
45
-
-
33645457226
-
Synergistic control of protein kinase C{gamma} activity by ionotropic and metabotropic glutamate receptor inputs in hippocampal neurons
-
Codazzi F, Di Cesare A, Chiulli N, Albanese A, Meyer T, Zacchetti D, Grohovaz F (2006) Synergistic control of protein kinase C{gamma} activity by ionotropic and metabotropic glutamate receptor inputs in hippocampal neurons. J Neurosci 26:3404-3411
-
(2006)
J Neurosci
, vol.26
, pp. 3404-3411
-
-
Codazzi, F.1
Di Cesare, A.2
Chiulli, N.3
Albanese, A.4
Meyer, T.5
Zacchetti, D.6
Grohovaz, F.7
-
46
-
-
0032582525
-
Protein kinase C as a molecular machine for decoding calcium and diacylglycerol signals
-
Oancea E, Meyer T (1998) Protein kinase C as a molecular machine for decoding calcium and diacylglycerol signals. Cell 95:307-318
-
(1998)
Cell
, vol.95
, pp. 307-318
-
-
Oancea, E.1
Meyer, T.2
-
47
-
-
0037013217
-
Regulation of PKC alpha activity by C1-C2 domain interactions
-
Slater SJ, Seiz JL, Cook AC, Buzas CJ, Malinowski SA, Kershner JL, Stagliano BA, Stubbs CD (2002) Regulation of PKC alpha activity by C1-C2 domain interactions. J Biol Chem 277:15277-15285
-
(2002)
J Biol Chem
, vol.277
, pp. 15277-15285
-
-
Slater, S.J.1
Seiz, J.L.2
Cook, A.C.3
Buzas, C.J.4
Malinowski, S.A.5
Kershner, J.L.6
Stagliano, B.A.7
Stubbs, C.D.8
-
48
-
-
21244504606
-
Diacylglycerol-induced membrane targeting and activation of protein kinase Cepsilon: Mechanistic differences between protein kinases Cdelta and Cepsilon
-
Stahelin RV, Digman MA, Medkova M, Ananthanarayanan B, Melowic HR, Rafter JD, Cho W (2005) Diacylglycerol-induced membrane targeting and activation of protein kinase Cepsilon: mechanistic differences between protein kinases Cdelta and Cepsilon. J Biol Chem 280:19784-19793
-
(2005)
J Biol Chem
, vol.280
, pp. 19784-19793
-
-
Stahelin, R.V.1
Digman, M.A.2
Medkova, M.3
Ananthanarayanan, B.4
Melowic, H.R.5
Rafter, J.D.6
Cho, W.7
-
49
-
-
35349021416
-
Identification of acidic amino acid residues in the protein kinase C alpha V5 domain that contribute to its insensitivity to diacylglycerol
-
Stensman H, Larsson C (2007) Identification of acidic amino acid residues in the protein kinase C alpha V5 domain that contribute to its insensitivity to diacylglycerol. J Biol Chem 282:28627-28638
-
(2007)
J Biol Chem
, vol.282
, pp. 28627-28638
-
-
Stensman, H.1
Larsson, C.2
-
50
-
-
78650942010
-
Crystal structure and allosteric activation of protein kinase C betaII
-
Leonard TA, Rozycki B, Saidi LF, Hummer G, Hurley JH (2011) Crystal structure and allosteric activation of protein kinase C betaII. Cell 144:55-66
-
(2011)
Cell
, vol.144
, pp. 55-66
-
-
Leonard, T.A.1
Rozycki, B.2
Saidi, L.F.3
Hummer, G.4
Hurley, J.H.5
-
51
-
-
0034687153
-
The C1 and C2 domains of protein kinase C are independent membrane targeting modules, with specificity for phosphatidylserine conferred by the C1 domain
-
Johnson JE, Giorgione J, Newton AC (2000) The C1 and C2 domains of protein kinase C are independent membrane targeting modules, with specificity for phosphatidylserine conferred by the C1 domain. Biochemistry 39:11360-11369
-
(2000)
Biochemistry
, vol.39
, pp. 11360-11369
-
-
Johnson, J.E.1
Giorgione, J.2
Newton, A.C.3
-
52
-
-
0032563203
-
The role of C2 domains in Ca2+ -activated and Ca2+ -independent protein kinase Cs in aplysia [published erratum appears in J Biol Chem 1998 Aug 28;273(35):22856]
-
Pepio AM, Fan X, Sossin WS (1998) The role of C2 domains in Ca2+ -activated and Ca2+ -independent protein kinase Cs in aplysia [published erratum appears in J Biol Chem 1998 Aug 28;273(35):22856]. J Biol Chem 273:19040-19048
-
(1998)
J Biol Chem
, vol.273
, pp. 19040-19048
-
-
Pepio, A.M.1
Fan, X.2
Sossin, W.S.3
-
53
-
-
0032477809
-
The C2 domain of the Ca(2+)-independent protein kinase C Apl II inhibits phorbol ester binding to the C1 domain in a phosphatidic acid-sensitive manner
-
Pepio AM, Sossin WS (1998) The C2 domain of the Ca(2+)-independent protein kinase C Apl II inhibits phorbol ester binding to the C1 domain in a phosphatidic acid-sensitive manner. Biochemistry 37:1256-1263
-
(1998)
Biochemistry
, vol.37
, pp. 1256-1263
-
-
Pepio, A.M.1
Sossin, W.S.2
-
54
-
-
47949111533
-
Physiological role for phosphatidic acid in the translocation of the novel protein kinase C Apl II in Aplysia neurons
-
Farah CA, Nagakura I, Weatherill D, Fan X, Sossin WS (2008) Physiological role for phosphatidic acid in the translocation of the novel protein kinase C Apl II in Aplysia neurons. Mol Cell Biol 28:4719-4733
-
(2008)
Mol Cell Biol
, vol.28
, pp. 4719-4733
-
-
Farah, C.A.1
Nagakura, I.2
Weatherill, D.3
Fan, X.4
Sossin, W.S.5
-
55
-
-
33644981789
-
Increased membrane affi nity of the C1 domain of protein kinase Cdelta compensates for the lack of involvement of its C2 domain in membrane recruitment
-
Giorgione JR, Lin JH, McCammon JA, Newton AC (2006) Increased membrane affi nity of the C1 domain of protein kinase Cdelta compensates for the lack of involvement of its C2 domain in membrane recruitment. J Biol Chem 281:1660-1669
-
(2006)
J Biol Chem
, vol.281
, pp. 1660-1669
-
-
Giorgione, J.R.1
Lin, J.H.2
McCammon, J.A.3
Newton, A.C.4
-
57
-
-
0032492686
-
Differential membrane-binding and activation mechanisms of protein kinase C-alpha and -epsilon
-
Medkova M, Cho W (1998) Differential membrane-binding and activation mechanisms of protein kinase C-alpha and -epsilon. Biochemistry 37:4892-4900
-
(1998)
Biochemistry
, vol.37
, pp. 4892-4900
-
-
Medkova, M.1
Cho, W.2
-
58
-
-
0344443675
-
The simultaneous production of phosphatidic acid and diacylglycerol is essential for the translocation of protein kinase Cepsilon to the plasma membrane in RBL-2H3 cells
-
Lopez-Andreo MJ, Gomez-Fernandez JC, Corbalan-Garcia S (2003) The simultaneous production of phosphatidic acid and diacylglycerol is essential for the translocation of protein kinase Cepsilon to the plasma membrane in RBL-2H3 cells. Mol Biol Cell 14:4885-4895
-
(2003)
Mol Biol Cell
, vol.14
, pp. 4885-4895
-
-
Lopez-Andreo, M.J.1
Gomez-Fernandez, J.C.2
Corbalan-Garcia, S.3
-
59
-
-
0035830830
-
Membrane translocation of novel protein kinase Cs is regulated by phosphorylation of the C2 domain
-
Pepio AM, Sossin WS (2001) Membrane translocation of novel protein kinase Cs is regulated by phosphorylation of the C2 domain. J Biol Chem 276:3846-3855
-
(2001)
J Biol Chem
, vol.276
, pp. 3846-3855
-
-
Pepio, A.M.1
Sossin, W.S.2
-
60
-
-
34547118860
-
Mechanism of diacylglycerol-induced membrane targeting and activation of protein kinase Ctheta
-
Melowic HR, Stahelin RV, Blatner NR, Tian W, Hayashi K, Altman A, Cho W (2007) Mechanism of diacylglycerol-induced membrane targeting and activation of protein kinase Ctheta. J Biol Chem 282:21467-21476
-
(2007)
J Biol Chem
, vol.282
, pp. 21467-21476
-
-
Melowic, H.R.1
Stahelin, R.V.2
Blatner, N.R.3
Tian, W.4
Hayashi, K.5
Altman, A.6
Cho, W.7
-
61
-
-
0030053828
-
Expression and characterization of Aplysia protein kinase C: A negative regulatory role for the e region
-
Sossin WS, Fan X, Saberi F (1996) Expression and characterization of Aplysia protein kinase C: a negative regulatory role for the E region. J Neurosci 16:10-18
-
(1996)
J Neurosci
, vol.16
, pp. 10-18
-
-
Sossin, W.S.1
Fan, X.2
Saberi, F.3
-
62
-
-
67650345546
-
A comparison of the membrane binding properties of C1B domains of PKCgamma, PKCdelta, and PKCepsilon
-
Sanchez-Bautista S, Corbalan-Garcia S, Perez-Lara A, Gomez-Fernandez JC (2009) A comparison of the membrane binding properties of C1B domains of PKCgamma, PKCdelta, and PKCepsilon. Biophys J 96:3638-3647
-
(2009)
Biophys J
, vol.96
, pp. 3638-3647
-
-
Sanchez-Bautista, S.1
Corbalan-Garcia, S.2
Perez-Lara, A.3
Gomez-Fernandez, J.C.4
-
63
-
-
0036947279
-
Protein kinase C delta (PKC delta): Activation mechanisms and functions
-
Kikkawa U, Matsuzaki H, Yamamoto T (2002) Protein kinase C delta (PKC delta): activation mechanisms and functions. J Biochem (Tokyo) 132:831-839
-
(2002)
J Biochem (Tokyo)
, vol.132
, pp. 831-839
-
-
Kikkawa, U.1
Matsuzaki, H.2
Yamamoto, T.3
-
64
-
-
0035811071
-
Phosphorylation sites of protein kinase C delta in H2O2-treated cells and its activation by tyrosine kinase in vitro
-
Konishi H, Yamauchi E, Taniguchi H, Yamamoto T, Matsuzaki H, Takemura Y, Ohmae K, Kikkawa U, Nishizuka Y (2001) Phosphorylation sites of protein kinase C delta in H2O2-treated cells and its activation by tyrosine kinase in vitro. Proc Natl Acad Sci USA 98:6587-6592
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 6587-6592
-
-
Konishi, H.1
Yamauchi, E.2
Taniguchi, H.3
Yamamoto, T.4
Matsuzaki, H.5
Takemura, Y.6
Ohmae, K.7
Kikkawa, U.8
Nishizuka, Y.9
-
65
-
-
0028851535
-
Development of a rapid approach to Identification of tyrosine phosphorylation sites: Application to PKC delta phosphorylated upon activation of the high affi nity receptor for IgE in rat basophilic leukemia cells
-
Szallasi Z, Denning MF, Chang EY, Rivera J, Yuspa SH, Lehel C, Olah Z, Anderson WB, Blumberg PM (1995) Development of a rapid approach to Identification of tyrosine phosphorylation sites: application to PKC delta phosphorylated upon activation of the high affi nity receptor for IgE in rat basophilic leukemia cells. Biochem Biophys Res Commun 214:888-894
-
(1995)
Biochem Biophys Res Commun
, vol.214
, pp. 888-894
-
-
Szallasi, Z.1
Denning, M.F.2
Chang, E.Y.3
Rivera, J.4
Yuspa, S.H.5
Lehel, C.6
Olah, Z.7
Anderson, W.B.8
Blumberg, P.M.9
-
66
-
-
0029912064
-
Identification of tyrosine 187 as a protein kinase C-delta phosphorylation site
-
Li W, Chen XH, Kelley CA, Alimandi M, Zhang J, Chen Q, Bottaro DP, Pierce JH (1996) Identification of tyrosine 187 as a protein kinase C-delta phosphorylation site. J Biol Chem 271:26404-26409
-
(1996)
J Biol Chem
, vol.271
, pp. 26404-26409
-
-
Li, W.1
Chen, X.H.2
Kelley, C.A.3
Alimandi, M.4
Zhang, J.5
Chen, Q.6
Bottaro, D.P.7
Pierce, J.H.8
-
68
-
-
0028145277
-
Tyrosine phosphorylation of protein kinase C-delta in response to its activation
-
Li W, Mischak H, Yu JC, Wang LM, Mushinski JF, Heidaran MA, Pierce JH (1994) Tyrosine phosphorylation of protein kinase C-delta in response to its activation. J Biol Chem 269:2349-2352
-
(1994)
J Biol Chem
, vol.269
, pp. 2349-2352
-
-
Li, W.1
Mischak, H.2
Yu, J.C.3
Wang, L.M.4
Mushinski, J.F.5
Heidaran, M.A.6
Pierce, J.H.7
-
69
-
-
0029924152
-
Activation of the epidermal growth factor receptor signal transduction pathway stimulates tyrosine phosphorylation of protein kinase C delta
-
Denning MF, Dlugosz AA, Threadgill DW, Magnuson T, Yuspa SH (1996) Activation of the epidermal growth factor receptor signal transduction pathway stimulates tyrosine phosphorylation of protein kinase C delta. J Biol Chem 271:5325-5331
-
(1996)
J Biol Chem
, vol.271
, pp. 5325-5331
-
-
Denning, M.F.1
Dlugosz, A.A.2
Threadgill, D.W.3
Magnuson, T.4
Yuspa, S.H.5
-
70
-
-
0028229299
-
Tyrosine phosphorylation and stimulation of protein kinase C delta from porcine spleen by src in vitro. Dependence on the activated state of protein kinase C delta
-
Gschwendt M, Kielbassa K, Kittstein W, Marks F (1994) Tyrosine phosphorylation and stimulation of protein kinase C delta from porcine spleen by src in vitro. Dependence on the activated state of protein kinase C delta. FEBS Lett 347:85-89
-
(1994)
FEBS Lett
, vol.347
, pp. 85-89
-
-
Gschwendt, M.1
Kielbassa, K.2
Kittstein, W.3
Marks, F.4
-
71
-
-
0032473826
-
Association of PKC delta and active Src in PMA-treated MCF-7 human breast cancer cells
-
Shanmugam M, Krett NL, Peters CA, Maizels ET, Murad FM, Kawakatsu H, Rosen ST, Hunzicker-Dunn M (1998) Association of PKC delta and active Src in PMA-treated MCF-7 human breast cancer cells. Oncogene 16:1649-1654
-
(1998)
Oncogene
, vol.16
, pp. 1649-1654
-
-
Shanmugam, M.1
Krett, N.L.2
Peters, C.A.3
Maizels, E.T.4
Murad, F.M.5
Kawakatsu, H.6
Rosen, S.T.7
Hunzicker-Dunn, M.8
-
72
-
-
0032473917
-
Activation of protein kinase C delta by the c-Abl tyrosine kinase in response to ionizing radiation
-
Yuan ZM, Utsugisawa T, Ishiko T, Nakada S, Huang Y, Kharbanda S, Weichselbaum R, Kufe D (1998) Activation of protein kinase C delta by the c-Abl tyrosine kinase in response to ionizing radiation. Oncogene 16:1643-1648
-
(1998)
Oncogene
, vol.16
, pp. 1643-1648
-
-
Yuan, Z.M.1
Utsugisawa, T.2
Ishiko, T.3
Nakada, S.4
Huang, Y.5
Kharbanda, S.6
Weichselbaum, R.7
Kufe, D.8
-
73
-
-
0034677930
-
Interaction between protein kinase C delta and the c-Abl tyrosine kinase in the cellular response to oxidative stress
-
Sun X, Wu F, Datta R, Kharbanda S, Kufe D (2000) Interaction between protein kinase C delta and the c-Abl tyrosine kinase in the cellular response to oxidative stress. J Biol Chem 275:7470-7473
-
(2000)
J Biol Chem
, vol.275
, pp. 7470-7473
-
-
Sun, X.1
Wu, F.2
Datta, R.3
Kharbanda, S.4
Kufe, D.5
-
74
-
-
0034810479
-
Carbachol stimulates TYR phosphorylation and association of PKCdelta and PYK2 in pancreas
-
Wrenn RW (2001) Carbachol stimulates TYR phosphorylation and association of PKCdelta and PYK2 in pancreas. Biochem Biophys Res Commun 282:882-886
-
(2001)
Biochem Biophys Res Commun
, vol.282
, pp. 882-886
-
-
Wrenn, R.W.1
-
75
-
-
0032474741
-
Tyrosine phosphorylation-dependent and -independent associations of protein kinase C-delta with Src family kinases in the RBL-2H3 mast cell line: Regulation of Src family kinase activity by protein kinase C-delta
-
Song JS, Swann PG, Szallasi Z, Blank U, Blumberg PM, Rivera J (1998) Tyrosine phosphorylation-dependent and -independent associations of protein kinase C-delta with Src family kinases in the RBL-2H3 mast cell line: regulation of Src family kinase activity by protein kinase C-delta. Oncogene 16:3357-3368
-
(1998)
Oncogene
, vol.16
, pp. 3357-3368
-
-
Song, J.S.1
Swann, P.G.2
Szallasi, Z.3
Blank, U.4
Blumberg, P.M.5
Rivera, J.6
-
76
-
-
0030976892
-
Association between v-Src and protein kinase C delta in v-Src-transformed fi broblasts
-
Zang Q, Lu Z, Curto M, Barile N, Shalloway D, Foster DA (1997) Association between v-Src and protein kinase C delta in v-Src-transformed fi broblasts. J Biol Chem 272:13275-13280
-
(1997)
J Biol Chem
, vol.272
, pp. 13275-13280
-
-
Zang, Q.1
Lu, Z.2
Curto, M.3
Barile, N.4
Shalloway, D.5
Foster, D.A.6
-
77
-
-
0027332733
-
Expression of an oncogenic rasHa gene in murine keratinocytes induces tyrosine phosphorylation and reduced activity of protein kinase C delta
-
Denning MF, Dlugosz AA, Howett MK, Yuspa SH (1993) Expression of an oncogenic rasHa gene in murine keratinocytes induces tyrosine phosphorylation and reduced activity of protein kinase C delta. J Biol Chem 268:26079-26081
-
(1993)
J Biol Chem
, vol.268
, pp. 26079-26081
-
-
Denning, M.F.1
Dlugosz, A.A.2
Howett, M.K.3
Yuspa, S.H.4
-
78
-
-
0027941342
-
Stimulation of the platelet-derived growth factor beta receptor signaling pathway activates protein kinase C-delta
-
Li W, Yu JC, Michieli P, Beeler JF, Ellmore N, Heidaran MA, Pierce JH (1994) Stimulation of the platelet-derived growth factor beta receptor signaling pathway activates protein kinase C-delta. Mol Cell Biol 14:6727-6735
-
(1994)
Mol Cell Biol
, vol.14
, pp. 6727-6735
-
-
Li, W.1
Yu, J.C.2
Michieli, P.3
Beeler, J.F.4
Ellmore, N.5
Heidaran, M.A.6
Pierce, J.H.7
-
79
-
-
0029041743
-
Carbachol, substance P, and phorbol ester promote the tyrosine phosphorylation of protein kinase C delta in salivary gland epithelial cells
-
Soltoff SP, Toker A (1995) Carbachol, substance P, and phorbol ester promote the tyrosine phosphorylation of protein kinase C delta in salivary gland epithelial cells. J Biol Chem 270:13490-13495
-
(1995)
J Biol Chem
, vol.270
, pp. 13490-13495
-
-
Soltoff, S.P.1
Toker, A.2
-
80
-
-
0031794093
-
Protein kinase C-delta activation and tyrosine phosphorylation in platelets
-
Moussazadeh M, Haimovich B (1998) Protein kinase C-delta activation and tyrosine phosphorylation in platelets. FEBS Lett 438:225-230
-
(1998)
FEBS Lett
, vol.438
, pp. 225-230
-
-
Moussazadeh, M.1
Haimovich, B.2
-
81
-
-
0031684848
-
Protein kinase C-delta is an important signaling molecule in insulin-like growth factor i receptormediated cell transformation
-
Li W, Jiang YX, Zhang J, Soon L, Flechner L, Kapoor V, Pierce JH, Wang LH (1998) Protein kinase C-delta is an important signaling molecule in insulin-like growth factor I receptormediated cell transformation. Mol Cell Biol 18:5888-5898
-
(1998)
Mol Cell Biol
, vol.18
, pp. 5888-5898
-
-
Li, W.1
Jiang, Y.X.2
Zhang, J.3
Soon, L.4
Flechner, L.5
Kapoor, V.6
Pierce, J.H.7
Wang, L.H.8
-
82
-
-
0033387429
-
Activation and tyrosine phosphorylation of protein kinase C delta in response to B cell antigen receptor stimulation
-
Popoff IJ, Deans JP (1999) Activation and tyrosine phosphorylation of protein kinase C delta in response to B cell antigen receptor stimulation. Mol Immunol 36:1005-1016
-
(1999)
Mol Immunol
, vol.36
, pp. 1005-1016
-
-
Popoff, I.J.1
Deans, J.P.2
-
83
-
-
0034989803
-
Modulation of PKCdelta tyrosine phosphorylation and activity in salivary and PC-12 cells by Src kinases
-
Benes C, Soltoff SP (2001) Modulation of PKCdelta tyrosine phosphorylation and activity in salivary and PC-12 cells by Src kinases. Am J Physiol Cell Physiol 280:C1498-C1510
-
(2001)
Am J Physiol Cell Physiol
, vol.280
-
-
Benes, C.1
Soltoff, S.P.2
-
84
-
-
0031964645
-
Anchoring proteins for protein kinase C: A means for isozyme selectivity
-
Mochly-Rosen D, Gordon AS (1998) Anchoring proteins for protein kinase C: a means for isozyme selectivity. FASEB J 12:35-42
-
(1998)
FASEB J
, vol.12
, pp. 35-42
-
-
Mochly-Rosen, D.1
Gordon, A.S.2
-
85
-
-
34250757608
-
Insight into intra-and inter-molecular interactions of PKC: Design of specific modulators of kinase function
-
Kheifets V, Mochly-Rosen D (2007) Insight into intra-and inter-molecular interactions of PKC: design of specific modulators of kinase function. Pharmacol Res 55:467-476
-
(2007)
Pharmacol Res
, vol.55
, pp. 467-476
-
-
Kheifets, V.1
Mochly-Rosen, D.2
-
86
-
-
0028938152
-
Localization of protein kinases by anchoring proteins: A theme in signal transduction
-
Mochly-Rosen D (1995) Localization of protein kinases by anchoring proteins: a theme in signal transduction. Science 268:247-251
-
(1995)
Science
, vol.268
, pp. 247-251
-
-
Mochly-Rosen, D.1
-
87
-
-
0030670399
-
The coatomer protein beta'-COP, a selective binding protein (RACK) for protein kinase Cepsilon
-
Csukai M, Chen CH, De Matteis MA, Mochly-Rosen D (1997) The coatomer protein beta'-COP, a selective binding protein (RACK) for protein kinase Cepsilon. J Biol Chem 272:29200-29206
-
(1997)
J Biol Chem
, vol.272
, pp. 29200-29206
-
-
Csukai, M.1
Chen, C.H.2
De Matteis, M.A.3
Mochly-Rosen, D.4
-
88
-
-
0141750583
-
Functional recycling of C2 domains throughout evolution: A comparative study of synaptotagmin, protein kinase C and phospholipase C by sequence, structural and modelling approaches
-
Jimenez JL, Smith GR, Contreras-Moreira B, Sgouros JG, Meunier FA, Bates PA, Schiavo G (2003) Functional recycling of C2 domains throughout evolution: a comparative study of synaptotagmin, protein kinase C and phospholipase C by sequence, structural and modelling approaches. J Mol Biol 333:621-639
-
(2003)
J Mol Biol
, vol.333
, pp. 621-639
-
-
Jimenez, J.L.1
Smith, G.R.2
Contreras-Moreira, B.3
Sgouros, J.G.4
Meunier, F.A.5
Bates, P.A.6
Schiavo, G.7
-
89
-
-
0037077256
-
The anchoring protein RACK1 links protein kinase Cepsilon to integrin beta chains. Requirements for adhesion and motility
-
Besson A, Wilson TL, Yong VW (2002) The anchoring protein RACK1 links protein kinase Cepsilon to integrin beta chains. Requirements for adhesion and motility. J Biol Chem 277:22073-22084
-
(2002)
J Biol Chem
, vol.277
, pp. 22073-22084
-
-
Besson, A.1
Wilson, T.L.2
Yong, V.W.3
-
90
-
-
0035839578
-
Binding specificity for RACK1 resides in the V5 region of beta II protein kinase C
-
Stebbins EG, Mochly-Rosen D (2001) Binding specificity for RACK1 resides in the V5 region of beta II protein kinase C. J Biol Chem 276:29644-29650
-
(2001)
J Biol Chem
, vol.276
, pp. 29644-29650
-
-
Stebbins, E.G.1
Mochly-Rosen, D.2
-
91
-
-
23044464191
-
RACK1 mediates activation of JNK by protein kinase C [corrected]
-
Lopez-Bergami P, Habelhah H, Bhoumik A, Zhang W, Wang LH, Ronai Z (2005) RACK1 mediates activation of JNK by protein kinase C [corrected]. Mol Cell 19:309-320
-
(2005)
Mol Cell
, vol.19
, pp. 309-320
-
-
Lopez-Bergami, P.1
Habelhah, H.2
Bhoumik, A.3
Zhang, W.4
Wang, L.H.5
Ronai, Z.6
-
92
-
-
4444313466
-
The receptor for activated C-kinase-I (RACK-I) anchors activated PKC-beta on melanosomes
-
Park HY, Wu H, Killoran CE, Gilchrest BA (2004) The receptor for activated C-kinase-I (RACK-I) anchors activated PKC-beta on melanosomes. J Cell Sci 117:3659-3668
-
(2004)
J Cell Sci
, vol.117
, pp. 3659-3668
-
-
Park, H.Y.1
Wu, H.2
Killoran, C.E.3
Gilchrest, B.A.4
-
93
-
-
0025908315
-
Identification of intracellular receptor proteins for activated protein kinase C
-
Mochly-Rosen D, Khaner H, Lopez J (1991) Identification of intracellular receptor proteins for activated protein kinase C. Proc Natl Acad Sci USA 88:3997-4000
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 3997-4000
-
-
Mochly-Rosen, D.1
Khaner, H.2
Lopez, J.3
-
94
-
-
0028805699
-
C2 region-derived peptides inhibit translocation and function of beta protein kinase C in vivo
-
Ron D, Luo J, Mochly-Rosen D (1995) C2 region-derived peptides inhibit translocation and function of beta protein kinase C in vivo. J Biol Chem 270:24180-24187
-
(1995)
J Biol Chem
, vol.270
, pp. 24180-24187
-
-
Ron, D.1
Luo, J.2
Mochly-Rosen, D.3
-
95
-
-
36749081143
-
Competitive inhibitors and allosteric activators of protein kinase C isoenzymes: A personal account and progress report on transferring academic discoveries to the clinic
-
Budas GR, Koyanagi T, Churchill EN, Mochly-Rosen D (2007) Competitive inhibitors and allosteric activators of protein kinase C isoenzymes: a personal account and progress report on transferring academic discoveries to the clinic. Biochem Soc Trans 35:1021-1026
-
(2007)
Biochem Soc Trans
, vol.35
, pp. 1021-1026
-
-
Budas, G.R.1
Koyanagi, T.2
Churchill, E.N.3
Mochly-Rosen, D.4
-
97
-
-
1942533628
-
A critical intramolecular interaction for protein kinase C epsilon translocation
-
Schechtman D, Craske ML, Kheifets V, Meyer T, Schechtman J, Mochly-Rosen D (2004) A critical intramolecular interaction for protein kinase C epsilon translocation. J Biol Chem 279(16):15831-15840
-
(2004)
J Biol Chem
, vol.279
, Issue.16
, pp. 15831-15840
-
-
Schechtman, D.1
Craske, M.L.2
Kheifets, V.3
Meyer, T.4
Schechtman, J.5
Mochly-Rosen, D.6
-
98
-
-
79951510534
-
Crystal structure of the eukaryotic 40S ribosomal subunit in complex with initiation factor 1
-
Rabl J, Leibundgut M, Ataide SF, Haag A, Ban N (2011) Crystal structure of the eukaryotic 40S ribosomal subunit in complex with initiation factor 1. Science 331:730-736
-
(2011)
Science
, vol.331
, pp. 730-736
-
-
Rabl, J.1
Leibundgut, M.2
Ataide, S.F.3
Haag, A.4
Ban, N.5
-
99
-
-
0346243923
-
Release of eIF6 (p27BBP) from the 60S subunit allows 80S ribosome assembly
-
Ceci M, Gaviraghi C, Gorrini C, Sala LA, Offenhauser N, Marchisio PC, Biffo S (2003) Release of eIF6 (p27BBP) from the 60S subunit allows 80S ribosome assembly. Nature 426:579-584
-
(2003)
Nature
, vol.426
, pp. 579-584
-
-
Ceci, M.1
Gaviraghi, C.2
Gorrini, C.3
Sala, L.A.4
Offenhauser, N.5
Marchisio, P.C.6
Biffo, S.7
-
100
-
-
12144253782
-
Regulation of eukaryotic translation by the RACK1 protein: A platform for signalling molecules on the ribosome
-
Nilsson J, Sengupta J, Frank J, Nissen P (2004) Regulation of eukaryotic translation by the RACK1 protein: a platform for signalling molecules on the ribosome. EMBO Rep 5:1137-1141
-
(2004)
EMBO Rep
, vol.5
, pp. 1137-1141
-
-
Nilsson, J.1
Sengupta, J.2
Frank, J.3
Nissen, P.4
-
101
-
-
60649119113
-
Signal transduction of constitutively active protein kinase C epsilon
-
Garczarczyk D, Toton E, Biedermann V, Rosivatz E, Rechfeld F, Rybczynska M, Hofmann J (2009) Signal transduction of constitutively active protein kinase C epsilon. Cell Signal 21:745-752
-
(2009)
Cell Signal
, vol.21
, pp. 745-752
-
-
Garczarczyk, D.1
Toton, E.2
Biedermann, V.3
Rosivatz, E.4
Rechfeld, F.5
Rybczynska, M.6
Hofmann, J.7
-
102
-
-
0031466995
-
Direct visualization of the translocation of the gamma-subspecies of protein kinase C in living cells using fusion proteins with green fluorescent protein
-
Sakai N, Sasaki K, Ikegaki N, Shirai Y, Ono Y, Saito N (1997) Direct visualization of the translocation of the gamma-subspecies of protein kinase C in living cells using fusion proteins with green fluorescent protein. J Cell Biol 139:1465-1476
-
(1997)
J Cell Biol
, vol.139
, pp. 1465-1476
-
-
Sakai, N.1
Sasaki, K.2
Ikegaki, N.3
Shirai, Y.4
Ono, Y.5
Saito, N.6
-
103
-
-
0033601367
-
Differential localization of protein kinase C delta by phorbol esters and related compounds using a fusion protein with green fluorescent protein
-
Wang QJ, Bhattacharyya D, Garfield S, Nacro K, Marquez VE, Blumberg PM (1999) Differential localization of protein kinase C delta by phorbol esters and related compounds using a fusion protein with green fluorescent protein. J Biol Chem 274:37233-37239
-
(1999)
J Biol Chem
, vol.274
, pp. 37233-37239
-
-
Wang, Q.J.1
Bhattacharyya, D.2
Garfield, S.3
Nacro, K.4
Marquez, V.E.5
Blumberg, P.M.6
-
104
-
-
0141844501
-
PICK1, an anchoring protein that specifically targets protein kinase Calpha to mitochondria selectively upon serum stimulation in NIH 3T3 cells
-
Wang WL, Yeh SF, Chang YI, Hsiao SF, Lian WN, Lin CH, Huang CY, Lin WJ (2003) PICK1, an anchoring protein that specifically targets protein kinase Calpha to mitochondria selectively upon serum stimulation in NIH 3T3 cells. J Biol Chem 278:37705-37712
-
(2003)
J Biol Chem
, vol.278
, pp. 37705-37712
-
-
Wang, W.L.1
Yeh, S.F.2
Chang, Y.I.3
Hsiao, S.F.4
Lian, W.N.5
Lin, C.H.6
Huang, C.Y.7
Lin, W.J.8
-
105
-
-
33750072605
-
Targeting protein kinase C activity reporter to discrete intracellular regions reveals spatiotemporal differences in agonist-dependent signaling
-
Gallegos LL, Kunkel MT, Newton AC (2006) Targeting protein kinase C activity reporter to discrete intracellular regions reveals spatiotemporal differences in agonist-dependent signaling. J Biol Chem 281:30947-30956
-
(2006)
J Biol Chem
, vol.281
, pp. 30947-30956
-
-
Gallegos, L.L.1
Kunkel, M.T.2
Newton, A.C.3
|