Functional recycling of C2 domains throughout evolution: A comparative study of synaptotagmin, protein kinase C and phospholipase C by sequence, structural and modelling approaches

Journal of Molecular Biology

Volumn 333, Issue 3, 2003, Pages 621-639

  Jiménez, José L ^a   Smith, Graham R ^a   Contreras Moreira, Bruno ^a   Sgouros, John G ^a   Meunier, Frederic A ^b   Bates, Paul A ^a   Schiavo, Giampietro ^a  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^b UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

C2 domains; Comparative modelling; Conservation analysis; Protein protein interaction; Proteomics

Indexed keywords

PHOSPHOLIPASE C; POLYPEPTIDE; PROTEIN KINASE C; SYNAPTOTAGMIN;

AMINO ACID SEQUENCE; ARTICLE; BINDING SITE; COMPARATIVE STUDY; EVOLUTION; MODEL; PREDICTION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN STRUCTURE; PROTEOMICS;

EID: 0141750583     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2003.08.052     Document Type: Article

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