Additional binding sites for anionic phospholipids and calcium ions in the crystal structures of complexes of the C2 domain of protein kinase Cα

Journal of Molecular Biology

Volumn 320, Issue 2, 2002, Pages 277-291

  Ochoa, Wendy F ^a   Corbalán Garcia, Senena ^b   Eritja, Ramon ^a   Rodríguez Alfaro, José A ^b   Gómez Fernández, Juan C ^b   Fita, Ignacio ^a   Verdaguer, Nuria ^a  

^a INSTITUT DE BIOLOGIA MOLECULAR DE BARCELONA   (Spain)

^b UNIVERSITY OF MURCIA   (Spain)

Author keywords

C2 domain; Phosphatidic acid; Phosphatidylserine; Protein kinase C; X ray structures

Indexed keywords

1,2 DIACETYLPHOSPHATIDYLSERINE; 1,2 DICAPROYLPHOSPHATIDIC ACID; 1,2 DICAPROYLPHOSPHATIDYLSERINE; 1,2 PHOSPHATIDYLSERINE; CALCIUM ION; HYDROCARBON; ISOENZYME; LIGAND; LYSINE; PHOSPHATE; PHOSPHATIDIC ACID; PHOSPHOLIPID DERIVATIVE; PROTEIN KINASE C ALPHA; SERINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING SITE; CRYSTAL STRUCTURE; CRYSTALLIZATION; ENZYME ACTIVITY; ENZYME SPECIFICITY; ENZYME STRUCTURE; PHOSPHOLIPID MEMBRANE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; SITE DIRECTED MUTAGENESIS;

EID: 0036297772     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-2836(02)00464-3     Document Type: Article

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