Expression and characterization of Aplysia protein kinase C: A negative regulatory role for the E region

Journal of Neuroscience

Volumn 16, Issue 1, 1996, Pages 10-18

  Sossin, Wayne S ^a   Fan, Xiaotang ^a   Saberi, Farzad ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

Aplysia; autonomous kinase; autophosphorylation; learning and memory; protein kinase C; synaptic plasticity

Indexed keywords

PROTEIN KINASE C;

APLYSIA; ARTICLE; ENZYME ACTIVATION; ENZYME ANALYSIS; ENZYME PHOSPHORYLATION; ENZYME PURIFICATION; NERVOUS SYSTEM; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

EID: 0030053828     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.16-01-00010.1996     Document Type: Article

References (43)

1. Akita Y, Ohno S, Konno Y, Yano A, Suzuki K (1990) Expression and properties of two distinct classes of the phorbol ester receptor family, four conventional protein kinase C types, and a novel protein kinase C. J Biol Chem 265:354-362.
2. Baxter G, Oto E, Daniel IS, Strulovici B (1992) Constitutive presence of a catalytic fragment of protein kinase C epsilon in a small cell lung carcinoma cell line. J Biol Chem 267:1910-1917.
3. Bell RM, Burns DJ (1991) Lipid activation of protein kinase C. J Biol Chem 266:4661-4664.
4. Braha O, Dale N, Hochner B, Klein M, Abrams TW, Kandel ER (1990) Second messengers involved in the two processes of presynaptic facilitation that contribute to sensitization and dishabituation in Aplysia sensory neurons. Proc Natl Acad Sci USA 87:2040-2044.
5. 2+ current of the sensory neurons in Aplysia. J Neurosci 13:1839-1851.
6. Brose N, Petrenko AG, Sudhof TC, Jahn R (1992) Synaptotagmin: a calcium sensor on the synaptic vesicle surface. Science 256:1021-1025.
7. Dekker LV, McIntyre P, Parker PJ (1993a) Altered substrate selectivity of PKC-eta pseudosubstrate site mutants. Febs Lett 329:129-33.
8. Dekker LV, McIntyre P, Parker PJ (1993b) Mutagenesis of the regulatory domain of rat protein kinase C-eta. A molecular basis for restricted histone kinase activity. J Biol Chem 268:19498-19504.
9. El Touny S, Khan W, Hannun Y (1990) Regulation of platelet protein kinase C by oleic acid. J Biol Chem 265:16437-16443.
10. 2+ influx in presynaptic facilitation. Nature 361:634-637.
11. Ghirardi M, Braha O, Hochner B, Montarolo PG, Kandel ER, Dale N (1992) Roles of PKA and PKC in facilitation of evoked and spontaneous transmitter release at depressed and nondepressed synapses in Aplysia sensory neurons. Neuron 9:479-489.
12. Hannun YA, Bell RM (1987) Mixed micellar assay for phorbol ester binding. Methods Enzymol 141:287-293.
13. Hannun YA, Loomis CR, Bell RM (1986) Protein kinase C activation in mixed micelles. Mechanistic implications of phospholipid, diacylglycerol, and calcium interdependencies. J Biol Chem 261:7184-7190.
14. 2+/calmodulin-dependent protein kinases. Annu Rev Biochem 61:559-601.
15. 2+-activated and phospholipid-dependent protein kinase. J Biol Chem 261:12134-12140.
16. Kaibuchi K, Fukumoto Y, Oku N, Takai Y, Arai K, Muramatsu M (1989) Molecular genetic analysis of the regulatory and catalytic domains of protein kinase C. J Biol Chem 264:13489-13496.
17. Khan WA, Blobe G, Halpern A, Taylor W, Wetsel WC, Burns D, Loomis C, Hannun YA (1993) Selective regulation of protein kinase C isoenzymes by oleic acid in human platelets. J Biol Chem 268:5063-5068.
18. Kiley S, Schaap D, Parker P, Hsieh LL, Jaken S (1990) Protein kinase C heterogeneity in GH4C1 rat pituitary cells Characterization of a Ca(2+)-independent phorbol ester receptor. J Biol Chem 265:15704-15712.
19. Koide H, Ogita K, Kikkawa U, Nishizuka Y (1992) Isolation and characterization of the epsilon subspecies of protein kinase C from rat brain. Proc Natl Acad Sci USA 89:1149-1153.
20. Kruger KE, Sossin WS, Sacktor TC, Bergold PJ, Beushausen S, Schwartz JH (1991) Cloning and characterization of Ca(2+)-dependent and Ca(2+)-independent PKCs expressed in Aplysia sensory cells. J Neurosci 11:2303-2313.
21. Land M, Islas-Trejo A, Freedman JH, Rubin CS (1994) Structure and expression of a novel, neuronal, protein kinase C (PKC1B) from Caenorhabditis elegans. J Biol Chem 269:9234-9244.
22. Luo JH, Weinstein IB (1993) Calcium-dependent activation of protein kinase C. The role of the C2 domain in divalent cation selectivity. J Biol Chem 268:23580-23584.
23. Nishizuka Y (1992) Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C. Science 258:607-614.
24. Olds JL, Alkon DL (1991) A role for protein kinase C in associative learning. New Biol 3:27-35.
25. Olivier AR, Parker PJ (1994) Bombesin, platelet-derived growth factor, and diacylglycerol induce selective membrane association and down-regulation of protein kinase C isotypes in Swiss 3T3 cells. J Biol Chem 269:2758-2763.
26. Osada S, Mizuno K, Saido TC, Akita Y, Suzuki K, Kuroki T, Ohno S (1990) A phorbol ester receptor/protein kinase, nPKC eta, a new member of the protein kinase C family predominantly expressed in lung and skin. J Biol Chem 265:22434-22440.
27. Patel G, Stabel S (1989) Expression of a functional protein kinase C-gamma using a baculovirus vector: purification and characterisation of a single protein kinase C iso-enzyme. Cellular Signalling 1:227-240.
28. Pfeffer LM, Eisenkraft BL, Reich NC, Improta T, Baxter G, Daniel IS, Strulovici B (1991) Transmembrane signaling by interferon alpha involves diacylglycerol production and activation of the epsilon isoform of protein kinase C in Daudi cells. Proc Natl Acad Sci USA 88:7988-7992.
29. Quest AF, Bardes ES, Bell RM (1994) A phorbol ester binding domain of protein kinase C gamma. High affinity binding to a glutathione-S-transferase/Cys2 fusion protein. J Biol Chem 269:2953-60.
30. Quest AF, Bell RM (1994) The regulatory region of protein kinase c-gamma: studies of phorbol ester binding to individual, and combined functional segments expressed as glutathione S-transferase fusion proteins indicate a complex mechanism of regulation by phospholipids, phorbol esters, and divalent cations. J Biol Chem 269:20000-20012.
31. Ron D, Mochly RD (1994) Agonists and antagonists of protein kinase C function, derived from its binding proteins. J Biol Chem 269:21395-21398.
32. Sacktor TC, Schwartz JH (1990) Sensitizing stimuli cause translocation of protein kinase C in Aplysia sensory neurons. Proc Natl Acad Sci USA 87:2036-2039.
33. Schaap D, Parker PJ (1990) Expression, purification, and characterization of protein kinase C-∈. J Biol Chem 265:7301-7307.
34. Schwartz JH (1993) Cognitive kinases. Proc Natl Acad Sci USA 90:8310-8313.
35. Sossin WS, Schwartz JH (1992) Selective activation of Ca(2+)-activated PKCs in Aplysia neurons by 5-HT. J Neurosci 12:1160-1168.
36. Sossin WS, Diaz AR, Schwartz JH (1993) Characterization of two isoforms of protein kinase C in the nervous system of Aplysia californica. J Biol Chem 268:5763-8.
37. 2+-independent protein kinase Cs contain an amino-terminal domain similar to the C2 consensus sequence. Trends Biochem Sci 18:207-208.
38. Sossin WS, Schwartz JH (1994) Translocation of protein kinase Cs in Aplysia neurons - evidence for complex regulation. Mol Brain Res 24:210-218.
39. Sossin WS, Sacktor TC, Schwartz JH (1994) Persistent activation of PKC during the development of long-term facilitation in Aplysia. Learning and Memory 1:189-202.
40. Strulovici B, Daniel IS, Baxter G, Knopf J, Sultzman L, Cherwinski H, Nestor JJ, Webb DR, Ransom J (1991) Distinct mechanisms of regulation of protein kinase C epsilon by hormones and phorbol diesters. J Biol Chem 266:168-173.
41. Sugita S, Goldsmith JR, Baxter DA, Byrne JH (1992) Involvement of protein kinase C in serotonin-induced spike broadening and synaptic facilitation in sensorimotor connections of Aplysia. J Neurophys 68:643-651.
42. Sugita S, Baxter DA, Byrne JH (1994) Activators of protein kinase c mimic serotonin-induced modulation of a voltage-dependent potassium current in pleural sensory neurons of Aplysia. J Neurophys 72:1240-1249,
43. Summers MD, Smith GE (1988) A manual of methods for baculovirus vectors and insect cell culture procedures. Texas Agricultural Experiment Station Bulletin No. 1555.