-
1
-
-
11144358645
-
High Frequency of Mutations of the PIK3CA Gene in Human Cancers
-
DOI 10.1126/science.1096502
-
Samuels Y, Wang Z, Bardelli A, Silliman N, Ptak J, Szabo S, et al. High frequency of mutations of the PIK3CA gene in human cancers. Science 2004;304:554. (Pubitemid 38541907)
-
(2004)
Science
, vol.304
, Issue.5670
, pp. 554
-
-
Samuels, Y.1
Wang, Z.2
Bardelli, A.3
Silliman, N.4
Ptak, J.5
Szabo, S.6
Yan, H.7
Gazdar, A.8
Powell, S.M.9
Riggins, G.J.10
Willson, J.K.V.11
Markowitz, S.12
Kinzler, K.W.13
Vogelstein, B.14
Velculescu, V.E.15
-
2
-
-
34548676803
-
PIK3CA mutation is predictive of poor survival in patients with colorectal cancer
-
DOI 10.1002/ijc.22890
-
Kato S, Iida S, Higuchi T, Ishikawa T, Takagi Y, Yasuno M, et al. PIK3CA mutation is predictive of poor survival in patients with colorectal cancer. Int J Cancer 2007;121:1771-8. (Pubitemid 47417296)
-
(2007)
International Journal of Cancer
, vol.121
, Issue.8
, pp. 1771-1778
-
-
Kato, S.1
Iida, S.2
Higuchi, T.3
Ishikawa, T.4
Takagi, Y.5
Yasuno, M.6
Enomoto, M.7
Uetake, H.8
Sugihara, K.9
-
3
-
-
22144452507
-
The prevalence of PIK3CA mutations in gastric and colon cancer
-
DOI 10.1016/j.ejca.2005.04.022, PII S0959804905003448
-
Velho S, Oliveira C, Ferreira A, Ferreira AC, Suriano G, Schwartz S Jr, et al. The prevalence of PIK3CA mutations in gastric and colon cancer. Eur J Cancer 2005;41:1649-54. (Pubitemid 40981849)
-
(2005)
European Journal of Cancer
, vol.41
, Issue.11
, pp. 1649-1654
-
-
Velho, S.1
Oliveira, C.2
Ferreira, A.3
Ferreira, A.C.4
Suriano, G.5
Schwartz Jr., S.6
Duval, A.7
Carneiro, F.8
Machado, J.C.9
Hamelin, R.10
Seruca, R.11
-
4
-
-
44449124376
-
Clinicopathological analysis of colorectal cancers with PIK3CA mutations in Middle Eastern population
-
DOI 10.1038/sj.onc.1211013, PII 1211013
-
Abubaker J, Bavi P, Al-Harbi S, Ibrahim M, Siraj AK, Al-Sanea N, et al. Clinicopathological analysis of colorectal cancers with PIK3CA mutations in Middle Eastern population. Oncogene 2008;27:3539-45. (Pubitemid 351793794)
-
(2008)
Oncogene
, vol.27
, Issue.25
, pp. 3539-3545
-
-
Abubaker, J.1
Bavi, P.2
Al-Harbi, S.3
Ibrahim, M.4
Siraj, A.K.5
Al-Sanea, N.6
Abduljabbar, A.7
Ashari, L.H.8
Alhomoud, S.9
Al-Dayel, F.10
Uddin, S.11
Al-Kuraya, K.S.12
-
5
-
-
76049098292
-
Prevalence and heterogeneity of KRAS, BRAF, and PIK3CA mutations in primary colorectal adenocarcinomas and their corresponding metastases
-
Baldus SE, Schaefer KL, Engers R, Hartleb D, Stoecklein NH, Gabbert HE. Prevalence and heterogeneity of KRAS, BRAF, and PIK3CA mutations in primary colorectal adenocarcinomas and their corresponding metastases. Clin Cancer Res 2010;16:790-9.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 790-799
-
-
Baldus, S.E.1
Schaefer, K.L.2
Engers, R.3
Hartleb, D.4
Stoecklein, N.H.5
Gabbert, H.E.6
-
6
-
-
38949133202
-
PIK3CA cancer mutations display gender and tissue specificity patterns
-
DOI 10.1002/humu.20648
-
Benvenuti S, Frattini M, Arena S, Zanon C, Cappelletti V, Coradini D, et al. PIK3CA cancer mutations display gender and tissue specificity patterns. Hum Mutat 2008;29:284-8. (Pubitemid 351240601)
-
(2008)
Human Mutation
, vol.29
, Issue.2
, pp. 284-288
-
-
Benvenuti, S.1
Frattini, M.2
Arena, S.3
Zanon, C.4
Cappelletti, V.5
Coradini, D.6
Daidone, M.G.7
Pilotti, S.8
Pierotti, M.A.9
Bardelli, A.10
-
7
-
-
42149083899
-
Mutations in the RAS-MAPK, PI(3)K (phosphatidylinositol-3-OH kinase) signaling network correlate with poor survival in a population-based series of colon cancers
-
DOI 10.1002/ijc.23388
-
Barault L, Veyrie N, Jooste V, Lecorre D, Chapusot C, Ferraz JM, et al. Mutations in the RAS-MAPK, PI(3)K (phosphatidylinositol-3-OH kinase) signaling network correlate with poor survival in a population-based series of colon cancers. Int J Cancer 2008;122:2255-9. (Pubitemid 351542328)
-
(2008)
International Journal of Cancer
, vol.122
, Issue.10
, pp. 2255-2259
-
-
Barault, L.1
Veyrie, N.2
Jooste, V.3
Lecorre, D.4
Chapusot, C.5
Ferraz, J.-M.6
Lievre, A.7
Cortet, M.8
Bouvier, A.-M.9
Rat, P.10
Roignot, P.11
Faivre, J.12
Laurent-Puig, P.13
Piard, F.14
-
8
-
-
68149165771
-
Prognostic and predictive value of common mutations for treatment response and survival in patients with metastatic colorectal cancer
-
Souglakos J, Philips J, Wang R, Marwah S, Silver M, Tzardi M, et al. Prognostic and predictive value of common mutations for treatment response and survival in patients with metastatic colorectal cancer. Br J Cancer 2009;101:465-72.
-
(2009)
Br J Cancer
, vol.101
, pp. 465-472
-
-
Souglakos, J.1
Philips, J.2
Wang, R.3
Marwah, S.4
Silver, M.5
Tzardi, M.6
-
9
-
-
48649092117
-
High-resolution melting analysis for rapid detection of KRAS, BRAF, and PIK3CA gene mutations in colorectal cancer
-
Simi L, Pratesi N, Vignoli M, Sestini R, Cianchi F, Valanzano R, et al. High-resolution melting analysis for rapid detection of KRAS, BRAF, and PIK3CA gene mutations in colorectal cancer. Am J Clin Pathol 2008;130:247-53.
-
(2008)
Am J Clin Pathol
, vol.130
, pp. 247-253
-
-
Simi, L.1
Pratesi, N.2
Vignoli, M.3
Sestini, R.4
Cianchi, F.5
Valanzano, R.6
-
10
-
-
44449133319
-
PIK3CA mutation in colorectal cancer: Relationship with genetic and epigenetic alterations
-
DOI 10.1593/neo.08336
-
Nosho K, Kawasaki T, Ohnishi M, Suemoto Y, Kirkner GJ, Zepf D, et al. PIK3CA mutation in colorectal cancer: relationship with genetic and epigenetic alterations. Neoplasia 2008;10:534-41. (Pubitemid 351770297)
-
(2008)
Neoplasia
, vol.10
, Issue.6
, pp. 534-541
-
-
Nosho, K.1
Kawasaki, T.2
Ohnishi, M.3
Suemoto, Y.4
Kirkner, G.J.5
Zepf, D.6
Yan, L.7
Longtine, J.A.8
Fuchs, C.S.9
Ogino, S.10
-
11
-
-
62449302407
-
PIK3CA mutations in colorectal cancer are associated with clinical resistance to EGFR-targeted monoclonal antibodies
-
Sartore-Bianchi A, Martini M, Molinari F, Veronese S, Nichelatti M, Artale S, et al. PIK3CA mutations in colorectal cancer are associated with clinical resistance to EGFR-targeted monoclonal antibodies. Cancer Res 2009;69:1851-7.
-
(2009)
Cancer Res
, vol.69
, pp. 1851-1857
-
-
Sartore-Bianchi, A.1
Martini, M.2
Molinari, F.3
Veronese, S.4
Nichelatti, M.5
Artale, S.6
-
12
-
-
63049111794
-
PIK3CA mutation is associated with poor prognosis among patients with curatively resected colon cancer
-
Ogino S, Nosho K, Kirkner GJ, Shima K, Irahara N, Kure S, et al. PIK3CA mutation is associated with poor prognosis among patients with curatively resected colon cancer. J Clin Oncol 2009;27:1477-84.
-
(2009)
J Clin Oncol
, vol.27
, pp. 1477-1484
-
-
Ogino, S.1
Nosho, K.2
Kirkner, G.J.3
Shima, K.4
Irahara, N.5
Kure, S.6
-
13
-
-
72549116865
-
PIK3CA mutations predict local recurrences in rectal cancer patients
-
He Y, Van't Veer LJ, Mikolajewska-Hanclich I, van Velthuysen ML, Zeestraten EC, Nagtegaal ID, et al. PIK3CA mutations predict local recurrences in rectal cancer patients. Clin Cancer Res 2009;15:6956-62.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 6956-6962
-
-
He, Y.1
Van't Veer, L.J.2
Mikolajewska-Hanclich, I.3
Van Velthuysen, M.L.4
Zeestraten, E.C.5
Nagtegaal, I.D.6
-
14
-
-
77955277111
-
Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: A retrospective consortium analysis
-
De Roock W, Claes B, Bernasconi D, De Schutter J, Biesmans B, Fountzilas G, et al. Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective consortium analysis. Lancet Oncol 2010;11:753-62.
-
(2010)
Lancet Oncol
, vol.11
, pp. 753-762
-
-
De Roock, W.1
Claes, B.2
Bernasconi, D.3
De Schutter, J.4
Biesmans, B.5
Fountzilas, G.6
-
15
-
-
77954215850
-
Markers for EGFR pathway activation as predictor of outcome in metastatic colorectal cancer patients treated with or without cetuximab
-
Tol J, Dijkstra JR, Klomp M, Teerenstra S, Dommerholt M, Vink-Borger ME, et al. Markers for EGFR pathway activation as predictor of outcome in metastatic colorectal cancer patients treated with or without cetuximab. Eur J Cancer 2010;46:1997-2009.
-
(2010)
Eur J Cancer
, vol.46
, pp. 1997-2009
-
-
Tol, J.1
Dijkstra, J.R.2
Klomp, M.3
Teerenstra, S.4
Dommerholt, M.5
Vink-Borger, M.E.6
-
16
-
-
84859840481
-
PIK3CA kinase domain mutation identifies a subgroup of stage III colon cancer patients with poor prognosis
-
Dordr
-
Farina Sarasqueta A, Zeestraten EC, van Wezel T, van Lijnschoten G, van Eijk R, Dekker JW, et al. PIK3CA kinase domain mutation identifies a subgroup of stage III colon cancer patients with poor prognosis. Cell Oncol (Dordr) 2011;34:523-31.
-
(2011)
Cell Oncol
, vol.34
, pp. 523-531
-
-
Farina Sarasqueta, A.1
Zeestraten, E.C.2
Van Wezel, T.3
Van Lijnschoten, G.4
Van Eijk, R.5
Dekker, J.W.6
-
17
-
-
20444374445
-
Mutant PIK3CA promotes cell growth and invasion of human cancer cells
-
DOI 10.1016/j.ccr.2005.05.014, PII S1535610805001601
-
Samuels Y, Diaz LA Jr, Schmidt-Kittler O, Cummins JM, Delong L, Cheong I, et al. Mutant PIK3CA promotes cell growth and invasion of human cancer cells. Cancer Cell 2005;7:561-73. (Pubitemid 40799249)
-
(2005)
Cancer Cell
, vol.7
, Issue.6
, pp. 561-573
-
-
Samuels, Y.1
Diaz Jr., L.A.2
Schmidt-Kittler, O.3
Cummins, J.M.4
DeLong, L.5
Cheong, I.6
Rago, C.7
Huso, D.L.8
Lengauer, C.9
Kinzler, K.W.10
Vogelstein, B.11
Velculescu, V.E.12
-
18
-
-
21144457217
-
Functional analysis of PIK3CA gene mutations in human colorectal cancer
-
DOI 10.1158/0008-5472.CAN-04-4114
-
Ikenoue T, Kanai F, Hikiba Y, Obata T, Tanaka Y, Imamura J, et al. Functional analysis of PIK3CA gene mutations in human colorectal cancer. Cancer Res 2005;65:4562-7. (Pubitemid 40740791)
-
(2005)
Cancer Research
, vol.65
, Issue.11
, pp. 4562-4567
-
-
Ikenoue, T.1
Kanai, F.2
Hikiba, Y.3
Obata, T.4
Tanaka, Y.5
Imamura, J.6
Ohta, M.7
Jazag, A.8
Guleng, B.9
Tateishi, K.10
Asaoka, Y.11
Matsumura, M.12
Kawabe, T.13
Omata, M.14
-
19
-
-
34250835879
-
Mutant PIK3CA-bearing colon cancer cells display increased metastasis in an orthotopic model
-
DOI 10.1158/0008-5472.CAN-07-0049
-
Guo XN, Rajput A, Rose R, Hauser J, Beko A, Kuropatwinski K, et al. Mutant PIK3CA-bearing colon cancer cells display increased metastasis in an orthotopic model. Cancer Res 2007;67:5851-8. (Pubitemid 46985019)
-
(2007)
Cancer Research
, vol.67
, Issue.12
, pp. 5851-5858
-
-
Guo, X.-N.1
Rajput, A.2
Rose, R.3
Hauser, J.4
Beko, A.5
Kuropatwinski, K.6
LeVa, C.7
Hoffman, R.M.8
Brattain, M.G.9
Wang, J.10
-
20
-
-
40649096375
-
Helical domain and kinase domain mutations in p110alpha of phosphatidylinositol 3-kinase induce gain of function by different mechanisms
-
DOI 10.1073/pnas.0712169105
-
Zhao L, Vogt PK. Helical domain and kinase domain mutations in p110alpha of phosphatidylinositol 3-kinase induce gain of function by different mechanisms. Proc Natl Acad Sci U S A 2008;105:2652-7. (Pubitemid 351520568)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.7
, pp. 2652-2657
-
-
Zhao, L.1
Vogt, P.K.2
-
21
-
-
70349939382
-
Biomarkers predicting clinical outcome of epidermal growth factor receptor-targeted therapy in metastatic colorectal cancer
-
Siena S, Sartore-Bianchi A, Di Nicolantonio F, Balfour J, Bardelli A. Biomarkers predicting clinical outcome of epidermal growth factor receptor-targeted therapy in metastatic colorectal cancer. J Natl Cancer Inst 2009;101:1308-24.
-
(2009)
J Natl Cancer Inst
, vol.101
, pp. 1308-1324
-
-
Siena, S.1
Sartore-Bianchi, A.2
Di Nicolantonio, F.3
Balfour, J.4
Bardelli, A.5
-
22
-
-
40749104889
-
BRAF mutation associated with other genetic events identifies a subset of aggressive papillary thyroid carcinoma
-
DOI 10.1111/j.1365-2265.2007.03077.x
-
Costa AM, Herrero A, Fresno MF, Heymann J, Alvarez JA, Cameselle-Teijeiro J, et al. BRAF mutation associated with other genetic events identifies a subset of aggressive papillary thyroid carcinoma. Clin Endocrinol (Oxf) 2008;68:618-34. (Pubitemid 351388702)
-
(2008)
Clinical Endocrinology
, vol.68
, Issue.4
, pp. 618-634
-
-
Costa, A.M.1
Herrero, A.2
Fresno, M.F.3
Heymann, J.4
Alvarez, J.A.5
Cameselle-Teijeiro, J.6
Garcia-Rostan, G.7
-
23
-
-
0037379904
-
High prevalence of BRAF mutations in thyroid cancer: Genetic evidence for constitutive activation of the RET/PTC-RAS-BRAF signaling pathway in papillary thyroid carcinoma
-
Kimura ET, Nikiforova MN, Zhu Z, Knauf JA, Nikiforov YE, Fagin JA. High prevalence of BRAF mutations in thyroid cancer: genetic evidence for constitutive activation of the RET/PTC-RAS-BRAF signaling pathway in papillary thyroid carcinoma. Cancer Res 2003;63:1454-7. (Pubitemid 36373628)
-
(2003)
Cancer Research
, vol.63
, Issue.7
, pp. 1454-1457
-
-
Kimura, E.T.1
Nikiforova, M.N.2
Zhu, Z.3
Knauf, J.A.4
Nikiforov, Y.E.5
Fagin, J.A.6
-
24
-
-
77949928737
-
Lifestyle factors and microsatellite instability in colorectal cancer: The evolving field of molecular pathological epidemiology
-
Ogino S, Stampfer M. Lifestyle factors and microsatellite instability in colorectal cancer: The evolving field of molecular pathological epidemiology. J Natl Cancer Inst 2010;102:365-7.
-
(2010)
J Natl Cancer Inst
, vol.102
, pp. 365-367
-
-
Ogino, S.1
Stampfer, M.2
-
25
-
-
79851511414
-
Molecular pathological epidemiology of colorectal neoplasia: An emerging transdisciplinary and interdisciplinary field
-
Ogino S, Chan AT, Fuchs CS, Giovannucci E. Molecular pathological epidemiology of colorectal neoplasia: an emerging transdisciplinary and interdisciplinary field. Gut 2011;60:397-411.
-
(2011)
Gut
, vol.60
, pp. 397-411
-
-
Ogino, S.1
Chan, A.T.2
Fuchs, C.S.3
Giovannucci, E.4
-
26
-
-
82555191051
-
Cancer immunology-analysis of host and tumor factors for personalized medicine
-
Ogino S, Galon J, Fuchs CS, Dranoff G. Cancer immunology-analysis of host and tumor factors for personalized medicine. Nat Rev Clin Oncol 2011;8:711-9.
-
(2011)
Nat Rev Clin Oncol
, vol.8
, pp. 711-719
-
-
Ogino, S.1
Galon, J.2
Fuchs, C.S.3
Dranoff, G.4
-
27
-
-
33749069927
-
CpG island methylator phenotype-low (CIMP-low) in colorectal cancer: Possible associations with male sex and KRAS mutations
-
DOI 10.2353/jmoldx.2006.060082
-
Ogino S, Kawasaki T, Kirkner GJ, Loda M, Fuchs CS. CpG island methylator phenotype-low (CIMP-low) in colorectal cancer: possible associations with male sex and KRAS mutations. J Mol Diagn 2006;8:582-8. (Pubitemid 44774157)
-
(2006)
Journal of Molecular Diagnostics
, vol.8
, Issue.5
, pp. 582-588
-
-
Ogino, S.1
Kawasaki, T.2
Kirkner, G.J.3
Loda, M.4
Fuchs, C.S.5
-
28
-
-
23844497341
-
Sensitive sequencing method for KRAS mutation detection by pyrosequencing
-
Ogino S, Kawasaki T, Brahmandam M, Yan L, Cantor M, Namgyal C, et al. Sensitive sequencing method for KRAS mutation detection by Pyrosequencing. J Mol Diagn 2005;7:413-21. (Pubitemid 41149657)
-
(2005)
Journal of Molecular Diagnostics
, vol.7
, Issue.3
, pp. 413-421
-
-
Ogino, S.1
Kawasaki, T.2
Brahmandam, M.3
Yan, L.4
Cantor, M.5
Nangyal, C.6
Mino-Kenudson, M.7
Lauwers, G.Y.8
Loda, M.9
Fuchs, C.S.10
-
29
-
-
58249089525
-
CpG island methylator phenotype, microsatellite instability, BRAF mutation and clinical outcome in colon cancer
-
Ogino S, Nosho K, Kirkner GJ, Kawasaki T, Meyerhardt JA, Loda M, et al. CpG island methylator phenotype, microsatellite instability, BRAF mutation and clinical outcome in colon cancer. Gut 2009;58:90-6.
-
(2009)
Gut
, vol.58
, pp. 90-96
-
-
Ogino, S.1
Nosho, K.2
Kirkner, G.J.3
Kawasaki, T.4
Meyerhardt, J.A.5
Loda, M.6
-
30
-
-
33744550591
-
Precision and performance characteristics of bisulfite conversion and real-time PCR (MethyLight) for quantitative DNA methylation analysis
-
DOI 10.2353/jmoldx.2006.050135
-
Ogino S, Kawasaki T, Brahmandam M, Cantor M, Kirkner GJ, Spiegelman D, et al. Precision and performance characteristics of bisulfite conversion and real-time PCR (MethyLight) for quantitative DNA methylation analysis. J Mol Diagn 2006;8:209-17. (Pubitemid 43811244)
-
(2006)
Journal of Molecular Diagnostics
, vol.8
, Issue.2
, pp. 209-217
-
-
Ogino, S.1
Kawasaki, T.2
Brahmandam, M.3
Cantor, M.4
Kirkner, G.J.5
Spiegelman, D.6
Makrigiorgos, G.M.7
Weisenberger, D.J.8
Laird, P.W.9
Loda, M.10
Fuchs, C.S.11
-
31
-
-
56649084987
-
Comprehensive biostatistical analysis of CpG island methylator phenotype in colorectal cancer using a large population-based sample
-
Nosho K, Irahara N, Shima K, Kure S, Kirkner GJ, Schernhammer ES, et al. Comprehensive biostatistical analysis of CpG island methylator phenotype in colorectal cancer using a large population-based sample. PLoS One 2008;3:e3698.
-
(2008)
PLoS One
, vol.3
-
-
Nosho, K.1
Irahara, N.2
Shima, K.3
Kure, S.4
Kirkner, G.J.5
Schernhammer, E.S.6
-
32
-
-
34247570795
-
Evaluation of markers for CpG Island Methylator Phenotype (CIMP) in colorectal cancer by a large population-based sample
-
DOI 10.2353/jmoldx.2007.060170
-
Ogino S, Kawasaki T, Kirkner GJ, Kraft P, Loda M, Fuchs CS. Evaluation of markers for CpG island methylator phenotype (CIMP) in colorectal cancer by a large population-based sample. J Mol Diagn 2007;9:305-14. (Pubitemid 47305066)
-
(2007)
Journal of Molecular Diagnostics
, vol.9
, Issue.3
, pp. 305-314
-
-
Ogino, S.1
Kawasaki, T.2
Kirkner, G.J.3
Kraft, P.4
Loda, M.5
Fuchs, C.S.6
-
33
-
-
33745541234
-
CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer
-
DOI 10.1038/ng1834, PII N1834
-
Weisenberger DJ, Siegmund KD, Campan M, Young J, Long TI, Faasse MA, et al. CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer. Nat Genet 2006;38:787-93. (Pubitemid 43980599)
-
(2006)
Nature Genetics
, vol.38
, Issue.7
, pp. 787-793
-
-
Weisenberger, D.J.1
Siegmund, K.D.2
Campan, M.3
Young, J.4
Long, T.I.5
Faasse, M.A.6
Kang, G.H.7
Widschwendter, M.8
Weener, D.9
Buchanan, D.10
Koh, H.11
Simms, L.12
Barker, M.13
Leggett, B.14
Levine, J.15
Kim, M.16
French, A.J.17
Thibodeau, S.N.18
Jass, J.19
Haile, R.20
Laird, P.W.21
more..
-
34
-
-
57349138824
-
A cohort study of tumoral LINE-1 hypomethylation and prognosis in colon cancer
-
Ogino S, Nosho K, Kirkner GJ, Kawasaki T, Chan AT, Schernhammer ES, et al. A cohort study of tumoral LINE-1 hypomethylation and prognosis in colon cancer. J Natl Cancer Inst 2008;100:1734-8.
-
(2008)
J Natl Cancer Inst
, vol.100
, pp. 1734-1738
-
-
Ogino, S.1
Nosho, K.2
Kirkner, G.J.3
Kawasaki, T.4
Chan, A.T.5
Schernhammer, E.S.6
-
35
-
-
77649145415
-
Precision of pyrosequencing assay to measure LINE-1 methylation in colon cancer, normal colonic mucosa, and peripheral blood cells
-
Irahara N, Nosho K, Baba Y, Shima K, Lindeman NI, Hazra A, et al. Precision of pyrosequencing assay to measure LINE-1 methylation in colon cancer, normal colonic mucosa, and peripheral blood cells. J Mol Diagn 2010;12:177-83.
-
(2010)
J Mol Diagn
, vol.12
, pp. 177-183
-
-
Irahara, N.1
Nosho, K.2
Baba, Y.3
Shima, K.4
Lindeman, N.I.5
Hazra, A.6
-
36
-
-
84863205460
-
Tumor TP53 expression status, body mass index and prognosis in colorectal cancer
-
Oct 31. [Epub ahead of print]
-
Morikawa T, Kuchiba A, Liao X, Imamura Y, Yamauchi M, Qian ZR, et al. Tumor TP53 expression status, body mass index and prognosis in colorectal cancer. Int J Cancer 2011 Oct 31. [Epub ahead of print].
-
(2011)
Int J Cancer
-
-
Morikawa, T.1
Kuchiba, A.2
Liao, X.3
Imamura, Y.4
Yamauchi, M.5
Qian, Z.R.6
-
37
-
-
77949759545
-
The role of the CpG island methylator phenotype in colorectal cancer prognosis depends on microsatellite instability screening status
-
Dahlin AM, Palmqvist R, Henriksson ML, Jacobsson M, Eklof V, Rutegard J, et al. The role of the CpG island methylator phenotype in colorectal cancer prognosis depends on microsatellite instability screening status. Clin Cancer Res 2010;16:1845-55.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 1845-1855
-
-
Dahlin, A.M.1
Palmqvist, R.2
Henriksson, M.L.3
Jacobsson, M.4
Eklof, V.5
Rutegard, J.6
-
38
-
-
79960311900
-
Association of CHFR promoter methylation with disease recurrence in locally advanced colon cancer
-
Tanaka M, Chang P, Li Y, Li D, Overman M, Maru DM, et al. Association of CHFR promoter methylation with disease recurrence in locally advanced colon cancer. Clin Cancer Res 2011;17:4531-40.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 4531-4540
-
-
Tanaka, M.1
Chang, P.2
Li, Y.3
Li, D.4
Overman, M.5
Maru, D.M.6
-
39
-
-
77955122376
-
New strategies in colorectal cancer: Biomarkers of response to epidermal growth factor receptor monoclonal antibodies and potential therapeutic targets in phosphoinositide 3-kinase and mitogen-activated protein kinase pathways
-
Dasari A, Messersmith WA. New strategies in colorectal cancer: biomarkers of response to epidermal growth factor receptor monoclonal antibodies and potential therapeutic targets in phosphoinositide 3-kinase and mitogen-activated protein kinase pathways. Clin Cancer Res 2010;16:3811-8.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 3811-3818
-
-
Dasari, A.1
Messersmith, W.A.2
-
40
-
-
74949089956
-
Three DNA methylation epigenotypes in human colorectal cancer
-
Yagi K, Akagi K, Hayashi H, Nagae G, Tsuji S, Isagawa T, et al. Three DNA methylation epigenotypes in human colorectal cancer. Clin Cancer Res 2010;16:21-33.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 21-33
-
-
Yagi, K.1
Akagi, K.2
Hayashi, H.3
Nagae, G.4
Tsuji, S.5
Isagawa, T.6
-
41
-
-
84862908001
-
Molecular analysis of colorectal tumors within a diverse patient cohort at a single institution
-
Sylvester BE, Huo D, Khramtsov A, Zhang J, Smalling RV, Olugbile S, et al. Molecular analysis of colorectal tumors within a diverse patient cohort at a single institution. Clin Cancer Res 2012;18: 350-9.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 350-359
-
-
Sylvester, B.E.1
Huo, D.2
Khramtsov, A.3
Zhang, J.4
Smalling, R.V.5
Olugbile, S.6
-
42
-
-
79952258995
-
KRAS mutation is associated with lung metastasis in patients with curatively resected colorectal cancer
-
Tie J, Lipton L, Desai J, Gibbs P, Jorissen RN, Christie M, et al. KRAS mutation is associated with lung metastasis in patients with curatively resected colorectal cancer. Clin Cancer Res 2011;17:1122-30.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 1122-1130
-
-
Tie, J.1
Lipton, L.2
Desai, J.3
Gibbs, P.4
Jorissen, R.N.5
Christie, M.6
-
43
-
-
80053528523
-
Colorectal cancers with microsatellite instability display unique miRNA profiles
-
Balaguer F, Moreira L, Lozano JJ, Link A, Ramirez G, Shen Y, et al. Colorectal cancers with microsatellite instability display unique miRNA profiles. Clin Cancer Res 2011;17:6239-49.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 6239-6249
-
-
Balaguer, F.1
Moreira, L.2
Lozano, J.J.3
Link, A.4
Ramirez, G.5
Shen, Y.6
-
44
-
-
84856512550
-
Predictive and prognostic roles of BRAF mutation in stage III colon cancer: Results from Intergroup Trial CALGB 89803
-
Ogino S, Shima K, Meyerhardt J, McCleary N, Ng K, Hollis D, et al. Predictive and prognostic roles of BRAF mutation in stage III colon cancer: results from Intergroup Trial CALGB 89803. Clin Cancer Res 2012;18:890-900.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 890-900
-
-
Ogino, S.1
Shima, K.2
Meyerhardt, J.3
McCleary, N.4
Ng, K.5
Hollis, D.6
-
45
-
-
84857777465
-
Infiltration of Lynch colorectal cancers by activated immune cells associates with early staging of the primary tumor and absence of lymph node metastases
-
Jan 26. [Epub ahead of print]
-
de Miranda NF, Goudkade D, Jordanova ES, Tops C, Hes F, Vasen H, et al. Infiltration of Lynch colorectal cancers by activated immune cells associates with early staging of the primary tumor and absence of lymph node metastases. Clin Cancer Res 2012 Jan 26. [Epub ahead of print].
-
(2012)
Clin Cancer Res
-
-
De Miranda, N.F.1
Goudkade, D.2
Jordanova, E.S.3
Tops, C.4
Hes, F.5
Vasen, H.6
-
46
-
-
65649086786
-
PIK3CA mutations are not a major determinant of resistance to the epidermal growth factor receptor inhibitor cetuximab in metastatic colorectal cancer
-
Prenen H, De Schutter J, Jacobs B, De Roock W, Biesmans B, Claes B, et al. PIK3CA mutations are not a major determinant of resistance to the epidermal growth factor receptor inhibitor cetuximab in metastatic colorectal cancer. Clin Cancer Res 2009;15:3184-8.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 3184-3188
-
-
Prenen, H.1
De Schutter, J.2
Jacobs, B.3
De Roock, W.4
Biesmans, B.5
Claes, B.6
-
47
-
-
78649473910
-
The BRAF V600E mutation is an independent prognostic factor for survival in stage II and stage III colon cancer patients
-
Farina-Sarasqueta A, van Lijnschoten G, Moerland E, Creemers GJ, Lemmens VE, Rutten HJ, et al. The BRAF V600E mutation is an independent prognostic factor for survival in stage II and stage III colon cancer patients. Ann Oncol 2010;21:2396-402.
-
(2010)
Ann Oncol
, vol.21
, pp. 2396-2402
-
-
Farina-Sarasqueta, A.1
Van Lijnschoten, G.2
Moerland, E.3
Creemers, G.J.4
Lemmens, V.E.5
Rutten, H.J.6
-
48
-
-
79960225815
-
Molecular alterations associated with liver metastases development in colorectal cancer patients
-
Bruin SC, He Y, Mikolajewska-Hanclich I, Liefers GJ, Klijn C, Vincent A, et al. Molecular alterations associated with liver metastases development in colorectal cancer patients. Br J Cancer 2011; 105:281-7.
-
(2011)
Br J Cancer
, vol.105
, pp. 281-287
-
-
Bruin, S.C.1
He, Y.2
Mikolajewska-Hanclich, I.3
Liefers, G.J.4
Klijn, C.5
Vincent, A.6
-
49
-
-
54249159640
-
PIK3CA cooperates with other phosphatidylinositol 30-kinase pathway mutations to effect oncogenic transformation
-
Oda K, Okada J, Timmerman L, Rodriguez-Viciana P, Stokoe D, Shoji K, et al. PIK3CA cooperates with other phosphatidylinositol 30-kinase pathway mutations to effect oncogenic transformation. Cancer Res 2008;68:8127-36.
-
(2008)
Cancer Res
, vol.68
, pp. 8127-8136
-
-
Oda, K.1
Okada, J.2
Timmerman, L.3
Rodriguez-Viciana, P.4
Stokoe, D.5
Shoji, K.6
-
50
-
-
33846563409
-
Why most published research findings are false
-
Ioannidis JP. Why most published research findings are false. PLoS Med 2005;2:e124.
-
(2005)
PLoS Med
, vol.2
-
-
Ioannidis, J.P.1
|