Nanoscale mid-infrared imaging of phase separation in a drug-polymer blend

Journal of Pharmaceutical Sciences

Volumn 101, Issue 6, 2012, Pages 2066-2073

  van Eerdenbrugh, Bernard ^a,b   Lo, Michael ^c   Kjoller, Kevin ^c   Marcott, Curtis ^d   Taylor, Lynne S ^a  

^a PURDUE UNIVERSITY   (United States)

^b DEPARTMENT OF PHARMACEUTICAL AND PHARMACOLOGICAL SCIENCES   (Belgium)

^c Anasys Instruments   (United States)

^d Light Light Solutions LLC   (United States)

Author keywords

Amorphous; Atomic force microscopy (AFM); FTIR; Infrared spectroscopy; Miscibility; Nanoscale mid infrared (mid IR); Phase separation; Physical characterization; Solid dispersion; Submicron resolution

Indexed keywords

FELODIPINE; POLYACRYLIC ACID;

ARTICLE; ATOMIC FORCE MICROSCOPY; DRUG DETERMINATION; DRUG STRUCTURE; MISCIBILITY; NANOSCALE MID INFRARED SPECTROSCOPY; SPECTROSCOPY;

EID: 84859783879     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.23099     Document Type: Article

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