The study of phase separation in amorphous freeze-dried systems. part I: Raman mapping and computational analysis of XRPD data in model polymer systems

Journal of Pharmaceutical Sciences

Volumn 100, Issue 1, 2011, Pages 206-222

  Padilla, Adora M ^a   Ivanisevic, Igor ^b   Yang, Yonglai ^b   Engers, David ^b   Bogner, Robin H ^a   Pikal, Michael J ^a,c  

^a UNIVERSITY OF CONNECTICUT   (United States)

^b Aptuit Inc   (United States)

^c KBI Biopharma Inc   (United States)

Author keywords

Amorphous; DSC; Glass transition; Lyophilization; Phase separation; Raman; X ray powder diffraction; XRPD

Indexed keywords

DEXTRAN; POLYMER; POVIDONE;

ARTICLE; DIFFERENTIAL SCANNING CALORIMETRY; FREEZE DRYING; INTERMETHOD COMPARISON; PHASE SEPARATION; RAMAN SPECTROMETRY; SENSITIVITY ANALYSIS; SIMULATION; X RAY POWDER DIFFRACTION;

EID: 78650064598     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.22269     Document Type: Article

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