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Volumn 2012, Issue , 2012, Pages

Notch, Wnt, and Hedgehog pathways in rhabdomyosarcoma: From single pathways to an integrated network

Author keywords

[No Author keywords available]

Indexed keywords

NOTCH RECEPTOR; SONIC HEDGEHOG PROTEIN; WNT PROTEIN;

EID: 84859778309     PISSN: 1357714X     EISSN: 13691643     Source Type: Journal    
DOI: 10.1155/2012/695603     Document Type: Review
Times cited : (34)

References (59)
  • 1
    • 0027534945 scopus 로고
    • Rearrangement of the PAX3 paired box gene in the paediatric solid tumour alveolar rhabdomyosarcoma
    • DOI 10.1038/ng0293-113
    • Barr F. G., Galili N., Holick J., Biegel J. A., Rovera G., Emanuell B. S., Rearrangement of the PAX3 paired box gene in the paediatric solid tumour alveolar rhabdomyosarcoma Nature Genetics 1993 3 2 113 117 (Pubitemid 23079791)
    • (1993) Nature Genetics , vol.3 , Issue.2 , pp. 113-117
    • Barr, F.G.1    Galili, N.2    Holick, J.3    Biegel, J.A.4    Rovera, G.5    Emanuell, B.S.6
  • 2
    • 0028364374 scopus 로고
    • Fusion of PAX7 to FKHR by the variant t(1;13)(p36;q14) translocation in alveolar rhabdomyosarcoma
    • Davis R. J., D'Cruz C. M., Lovell M. A., Biegel J. A., Barr F. G., Fusion of PAX7 to FKHR by the variant t(1;13)(p36;q14) translocation in alveolar rhabdomyosarcoma Cancer Research 1994 54 11 2869 2872 (Pubitemid 24187765)
    • (1994) Cancer Research , vol.54 , Issue.11 , pp. 2869-2872
    • Davis, R.J.1    D'Cruz, C.M.2    Lovell, M.A.3    Biegel, J.A.4    Barr, F.G.5
  • 4
    • 0034088133 scopus 로고    scopus 로고
    • Novel genomic imbalances in embryonal rhabdomyosarcoma revealed by comparative genomic hybridization and fluorescence in situ hybridization: An intergroup rhabdomyosarcoma study
    • DOI 10.1002/(SICI)1098-2264(200004)27:4<337::AID-GCC1>3.0.CO;2-1
    • Bridge J. A., Liu J., Weibolt V., Baker K. S., Perry D., Kruger R., Qualman S., Barr F., Sorensen P., Triche T., Suijkerbuijk R., Novel genomic imbalances in embryonal rhabdomyosarcoma revealed by comparative genomic hybridization and fluorescence in situ hybridization: an intergroup rhabdomyosarcoma study Genes Chromosomes and Cancer 2000 27 4 337 344 (Pubitemid 30127620)
    • (2000) Genes Chromosomes and Cancer , vol.27 , Issue.4 , pp. 337-344
    • Bridge, J.A.1    Liu, J.2    Weibolt, V.3    Baker, K.S.4    Perry, D.5    Kruger, R.6    Qualman, S.7    Barr, F.8    Sorensen, P.9    Triche, T.10    Suijkerbuijk, R.11
  • 5
    • 0033617522 scopus 로고    scopus 로고
    • Notch signaling: Cell fate control and signal integration in development
    • DOI 10.1126/science.284.5415.770
    • Artavanis-Tsakonas S., Rand M. D., Lake R. J., Notch signaling: cell fate control and signal integration in development Science 1999 284 5415 770 776 (Pubitemid 29291335)
    • (1999) Science , vol.284 , Issue.5415 , pp. 770-776
    • Artavanis-Tsakonas, S.1    Rand, M.D.2    Lake, R.J.3
  • 6
    • 24344443668 scopus 로고    scopus 로고
    • The regulation of Notch signaling in muscle stem cell activation and postnatal myogenesis
    • DOI 10.1016/j.semcdb.2005.07.002, PII S1084952105000832, Biology of Hypoxia and Myogenesis and Muscle Disease
    • Luo D., Renault V. M., Rando T. A., The regulation of Notch signaling in muscle stem cell activation and postnatal myogenesis Seminars in Cell and Developmental Biology 2005 16 4-5 612 622 (Pubitemid 41247884)
    • (2005) Seminars in Cell and Developmental Biology , vol.16 , Issue.4-5 , pp. 612-622
    • Luo, D.1    Renault, V.M.2    Rando, T.A.3
  • 7
    • 0033136717 scopus 로고    scopus 로고
    • Deficient T cell fate specification in mice with an induced inactivation of Notch1
    • DOI 10.1016/S1074-7613(00)80054-0
    • Radtke F., Wilson A., Stark G., Bauer M., Van Meerwijk J., MacDonald H. R., Aguet M., Deficient T cell fate specification in mice with an induced inactivation of Notch1 Immunity 1999 10 5 547 558 (Pubitemid 29262657)
    • (1999) Immunity , vol.10 , Issue.5 , pp. 547-558
    • Radtke, F.1    Wilson, A.2    Stark, G.3    Bauer, M.4    Van Meerwijk, J.5    MacDonald, H.R.6    Aguet, M.7
  • 9
    • 0030920376 scopus 로고    scopus 로고
    • The mouse mammary tumor associated gene INT3 is a unique member of the NOTCH gene family (NOTCH4)
    • Gallahan D., Callahan R., The mouse mammary tumor associated gene INT3 is a unique member of the NOTCH gene family (NOTCH4) Oncogene 1997 14 16 1883 1890 (Pubitemid 27217801)
    • (1997) Oncogene , vol.14 , Issue.16 , pp. 1883-1890
    • Gallahan, D.1    Callahan, R.2
  • 10
    • 0242456129 scopus 로고    scopus 로고
    • Notch signaling as a therapeutic target in cancer: A new approach to the development of cell fate modifying agents
    • Nickoloff B. J., Osborne B. A., Miele L., Notch signaling as a therapeutic target in cancer: a new approach to the development of cell fate modifying agents Oncogene 2003 22 43 6598 6608 (Pubitemid 37372340)
    • (2003) Oncogene , vol.22 , Issue.43 , pp. 6598-6608
    • Nickoloff, B.J.1    Osborne, B.A.2    Miele, L.3
  • 11
    • 49649103793 scopus 로고    scopus 로고
    • Critical role of notch signaling in osteosarcoma invasion and metastasis
    • Zhang P., Yang Y., Zweidler-McKay P. A., Hughes D. P. M., Critical role of notch signaling in osteosarcoma invasion and metastasis Clinical Cancer Research 2008 14 10 2962 2969
    • (2008) Clinical Cancer Research , vol.14 , Issue.10 , pp. 2962-2969
    • Zhang, P.1    Yang, Y.2    Zweidler-Mckay, P.A.3    Hughes, D.P.M.4
  • 13
    • 33747874155 scopus 로고    scopus 로고
    • Notch pathway inhibition depletes stem-like cells and blocks engraftment in embryonal brain tumors
    • DOI 10.1158/0008-5472.CAN-06-0858
    • Fan X., Matsui W., Khaki L., Stearns D., Chun J., Li Y. M., Eberhart C. G., Notch pathway inhibition depletes stem-like cells and blocks engraftment in embryonal brain tumors Cancer Research 2006 66 15 7445 7452 (Pubitemid 44289197)
    • (2006) Cancer Research , vol.66 , Issue.15 , pp. 7445-7452
    • Fan, X.1    Matsui, W.2    Khaki, L.3    Stearns, D.4    Chun, J.5    Li, Y.-M.6    Eberhart, C.G.7
  • 15
    • 0036744815 scopus 로고    scopus 로고
    • The regulation of Notch signaling controls satellite cell activation and cell fate determination in postnatal myogenesis
    • Conboy I. M., Rando T. A., The regulation of Notch signaling controls satellite cell activation and cell fate determination in postnatal myogenesis Developmental Cell 2002 3 3 397 409
    • (2002) Developmental Cell , vol.3 , Issue.3 , pp. 397-409
    • Conboy, I.M.1    Rando, T.A.2
  • 16
    • 0030453171 scopus 로고    scopus 로고
    • Notch signaling inhibits muscle cell differentiation through a CBF1-independent pathway
    • Shawber C., Nofziger D., Hsieh J. J. D., Lindsell C., Bgler O., Hayward D., Weinmaster G., Notch signaling inhibits muscle cell differentiation through a CBF1-independent pathway Development 1996 122 12 3765 3773 (Pubitemid 27033873)
    • (1996) Development , vol.122 , Issue.12 , pp. 3765-3773
    • Shawber, C.1    Nofziger, D.2    Hsieh, J.J.-D.3    Lindsell, C.4    Bogler, O.5    Hayward, D.6    Weinmaster, G.7
  • 17
    • 0032915458 scopus 로고    scopus 로고
    • Notch signaling imposes two distinct blocks in the differentiation of C2C12 myoblasts
    • Nofziger D., Miyamoto A., Lyons K. M., Weinmaster G., Notch signaling imposes two distinct blocks in the differentiation of C2C12 myoblasts Development 1999 126 8 1689 1702 (Pubitemid 29204333)
    • (1999) Development , vol.126 , Issue.8 , pp. 1689-1702
    • Nofziger, D.1    Miyamoto, A.2    Lyons, K.M.3    Weinmaster, G.4
  • 18
    • 79551717942 scopus 로고    scopus 로고
    • Notch pathway inhibition significantly reduces rhabdomyosarcoma invasiveness and mobility in vitro
    • Roma J., Masi A., Revents J., De Toledo J. S., Gallego S., Notch pathway inhibition significantly reduces rhabdomyosarcoma invasiveness and mobility in vitro Clinical Cancer Research 2011 17 3 505 513
    • (2011) Clinical Cancer Research , vol.17 , Issue.3 , pp. 505-513
    • Roma, J.1    Masi, A.2    Revents, J.3    De Toledo, J.S.4    Gallego, S.5
  • 19
    • 0019133661 scopus 로고
    • Mutations affecting segment number and polarity in Drosophila
    • DOI 10.1038/287795a0
    • Nusslein-Volhard C., Wieschaus E., Mutations affecting segment number and polarity in Drosophila Nature 1980 287 5785 795 801 (Pubitemid 11214475)
    • (1980) Nature , vol.287 , Issue.5785 , pp. 795-801
    • Nusslein-Volhard, C.1    Wieschaus, E.2
  • 21
    • 34548306769 scopus 로고    scopus 로고
    • Patching the gaps in Hedgehog signalling
    • DOI 10.1038/ncb435, PII NCB435
    • Rohatgi R., Scott M. P., Patching the gaps in Hedgehog signalling Nature Cell Biology 2007 9 9 1005 1009 (Pubitemid 47338138)
    • (2007) Nature Cell Biology , vol.9 , Issue.9 , pp. 1005-1009
    • Rohatgi, R.1    Scott, M.P.2
  • 26
    • 79954486712 scopus 로고    scopus 로고
    • Clinical implications of hedgehog signaling pathway inhibitors
    • Liu H., Gu D., Xie J., Clinical implications of hedgehog signaling pathway inhibitors Chinese Journal of Cancer 2011 30 1 13 26
    • (2011) Chinese Journal of Cancer , vol.30 , Issue.1 , pp. 13-26
    • Liu, H.1    Gu, D.2    Xie, J.3
  • 27
    • 0031837454 scopus 로고    scopus 로고
    • Rhabdomyosarcomas and radiation hypersensitivity in a mouse model of Gorlin syndrome
    • DOI 10.1038/nm0598-619
    • Hahn H., Wojnowski L., Zimmer A. M., Hall J., Miller G., Zimmer A., Rhabdomyosarcomas and radiation hypersensitivity in a mouse model of Gorlin syndrome Nature Medicine 1998 4 5 619 622 (Pubitemid 28237364)
    • (1998) Nature Medicine , vol.4 , Issue.5 , pp. 619-622
    • Hahn, H.1    Wojnowski, L.2    Zimmer, A.M.3    Hall, J.4    Miller, G.5    Zimmer, A.6
  • 30
    • 78649814616 scopus 로고    scopus 로고
    • Activation of the hedgehog pathway confers a poor prognosis in embryonal and fusion gene-negative alveolar rhabdomyosarcoma
    • Zibat A., Missiaglia E., Rosenberger A., Pritchard-Jones K., Shipley J., Hahn H., Fulda S., Activation of the hedgehog pathway confers a poor prognosis in embryonal and fusion gene-negative alveolar rhabdomyosarcoma Oncogene 2010 29 48 6323 6330
    • (2010) Oncogene , vol.29 , Issue.48 , pp. 6323-6330
    • Zibat, A.1    Missiaglia, E.2    Rosenberger, A.3    Pritchard-Jones, K.4    Shipley, J.5    Hahn, H.6    Fulda, S.7
  • 31
    • 80052655551 scopus 로고    scopus 로고
    • Hedgehog pathway activity in pediatric embryonal rhabdomyosarcoma and undifferentiated sarcoma: A report from the Children's Oncology Group
    • Pressey J. G., Anderson J. R., Crossman D. K., Lynch J. C., Barr F. G., Hedgehog pathway activity in pediatric embryonal rhabdomyosarcoma and undifferentiated sarcoma: a report from the Children's Oncology Group Pediatric Blood and Cancer 2011 57 6 930 938
    • (2011) Pediatric Blood and Cancer , vol.57 , Issue.6 , pp. 930-938
    • Pressey, J.G.1    Anderson, J.R.2    Crossman, D.K.3    Lynch, J.C.4    Barr, F.G.5
  • 32
    • 75749133243 scopus 로고    scopus 로고
    • Increased expression of the hedgehog signaling pathway in pediatric solid malignancies
    • Oue T., Yoneda A., Uehara S., Yamanaka H., Fukuzawa M., Increased expression of the hedgehog signaling pathway in pediatric solid malignancies Journal of Pediatric Surgery 2010 45 2 387 392
    • (2010) Journal of Pediatric Surgery , vol.45 , Issue.2 , pp. 387-392
    • Oue, T.1    Yoneda, A.2    Uehara, S.3    Yamanaka, H.4    Fukuzawa, M.5
  • 33
  • 34
    • 79952820588 scopus 로고    scopus 로고
    • Reduction of human embryonal rhabdomyosarcoma tumor growth by inhibition of the hedgehog signaling pathway
    • Tostar U., Toftgrd R., Zaphiropoulos P. G., Shimokawa T., Reduction of human embryonal rhabdomyosarcoma tumor growth by inhibition of the hedgehog signaling pathway Genes and Cancer 2010 1 9 941 951
    • (2010) Genes and Cancer , vol.1 , Issue.9 , pp. 941-951
    • Tostar, U.1    Toftgrd, R.2    Zaphiropoulos, P.G.3    Shimokawa, T.4
  • 35
    • 79551580687 scopus 로고    scopus 로고
    • Hedgehog signal inhibitor forskolin suppresses cell proliferation and tumor growth of human rhabdomyosarcoma xenograft
    • Yamanaka H., Oue T., Uehara S., Fukuzawa M., Hedgehog signal inhibitor forskolin suppresses cell proliferation and tumor growth of human rhabdomyosarcoma xenograft Journal of Pediatric Surgery 2011 46 2 320 325
    • (2011) Journal of Pediatric Surgery , vol.46 , Issue.2 , pp. 320-325
    • Yamanaka, H.1    Oue, T.2    Uehara, S.3    Fukuzawa, M.4
  • 37
    • 67650289584 scopus 로고    scopus 로고
    • Mechanisms of Hedgehog pathway activation in cancer and implications for therapy
    • Scales S. J., de Sauvage F. J., Mechanisms of Hedgehog pathway activation in cancer and implications for therapy Trends in Pharmacological Sciences 2009 30 6 303 312
    • (2009) Trends in Pharmacological Sciences , vol.30 , Issue.6 , pp. 303-312
    • Scales, S.J.1    De Sauvage, F.J.2
  • 38
    • 34547107319 scopus 로고    scopus 로고
    • WNT signaling pathway and stem cell signaling network
    • DOI 10.1158/1078-0432.CCR-06-2316
    • Katoh M., Katoh M., WNT signaling pathway and stem cell signaling network Clinical Cancer Research 2007 13 14 4042 4045 (Pubitemid 47105963)
    • (2007) Clinical Cancer Research , vol.13 , Issue.14 , pp. 4042-4045
    • Katoh, M.1    Katoh, M.2
  • 39
    • 24944494556 scopus 로고    scopus 로고
    • Wnt signaling through canonical and non-canonical pathways: Recent progress
    • DOI 10.1080/08977190500125746, PII T4161837710173
    • Widelitz R., Wnt signaling through canonical and non-canonical pathways: recent progress Growth Factors 2005 23 2 111 116 (Pubitemid 43203058)
    • (2005) Growth Factors , vol.23 , Issue.2 , pp. 111-116
    • Widelitz, R.1
  • 40
    • 78650482080 scopus 로고    scopus 로고
    • Noncanonical Wnt signaling in vertebrate development, stem cells, and diseases
    • Sugimura R., Li L., Noncanonical Wnt signaling in vertebrate development, stem cells, and diseases Birth Defects Research C 2010 90 4 243 256
    • (2010) Birth Defects Research C , vol.90 , Issue.4 , pp. 243-256
    • Sugimura, R.1    Li, L.2
  • 41
    • 0142056101 scopus 로고    scopus 로고
    • The Wnt signaling pathway in solid childhood tumors
    • DOI 10.1016/S0304-3835(03)00367-7
    • Koesters R., Von Knebel Doeberitz M., The Wnt signaling pathway in solid childhood tumors Cancer Letters 2003 198 2 123 138 (Pubitemid 37297785)
    • (2003) Cancer Letters , vol.198 , Issue.2 , pp. 123-138
    • Koesters, R.1    Von Knebel Doeberitz, M.2
  • 42
    • 0033486152 scopus 로고    scopus 로고
    • Catenin signaling and cancer
    • Morin P. J., -catenin signaling and cancer BioEssays 1999 21 12 1021 1030
    • (1999) BioEssays , vol.21 , Issue.12 , pp. 1021-1030
    • Morin, P.J.1
  • 43
    • 33645738114 scopus 로고    scopus 로고
    • Diagnostic and prognostic impact of beta-catenin alterations in pediatric liver tumors
    • Yamaoka H., Ohtsu K., Sueda T., Yokoyama T., Hiyama E., Diagnostic and prognostic impact of beta-catenin alterations in pediatric liver tumors Oncology reports. 2006 15 3 551 556
    • (2006) Oncology Reports. , vol.15 , Issue.3 , pp. 551-556
    • Yamaoka, H.1    Ohtsu, K.2    Sueda, T.3    Yokoyama, T.4    Hiyama, E.5
  • 44
    • 0345356929 scopus 로고    scopus 로고
    • Wnt5a inhibits B cell proliferation and functions as a tumor suppressor in hematopoietic tissue
    • DOI 10.1016/S1535-6108(03)00268-X
    • Liang H., Chen Q., Coles A. H., Anderson S. J., Pihan G., Bradley A., Gerstein R., Jurecic R., Jones S. N., Wnt5a inhibits B cell proliferation and functions as a tumor suppressor in hematopoietic tissue Cancer Cell 2003 4 5 349 360 (Pubitemid 37491096)
    • (2003) Cancer Cell , vol.4 , Issue.5 , pp. 349-360
    • Liang, H.1    Chen, Q.2    Coles, A.H.3    Anderson, S.J.4    Pihan, G.5    Bradley, A.6    Gerstein, R.7    Jurecic, R.8    Jones, S.N.9
  • 45
    • 40749119357 scopus 로고    scopus 로고
    • WNT5A exhibits tumor-suppressive activity through antagonizing the Wnt/β-catenin signaling, and is frequently methylated in colorectal cancer
    • DOI 10.1158/1078-0432.CCR-07-1644
    • Ying J., Li H., Yu J., Ka M. N., Fan F. P., Wong S. C. C., Chan A. T. C., Sung J. J. Y., Tao Q., WNT5A exhibits tumor-suppressive activity through antagonizing the Wnt/ -catenin signaling, and is frequently methylated in colorectal cancer Clinical Cancer Research 2008 14 1 55 61 (Pubitemid 351377978)
    • (2008) Clinical Cancer Research , vol.14 , Issue.1 , pp. 55-61
    • Ying, J.1    Li, H.2    Yu, J.3    Ka, M.N.4    Fan, F.P.5    Wong, S.C.C.6    Chan, A.T.C.7    Sung, J.J.Y.8    Tao, Q.9
  • 46
    • 0037081290 scopus 로고    scopus 로고
    • Loss of Wnt-5a protein is associated with early relapse in invasive ductal breast carcinomas
    • Jnsson M., Dejmek J., Bendahl P. O., Andersson T., Loss of Wnt-5a protein is associated with early relapse in invasive ductal breast carcinomas Cancer Research 2002 62 2 409 416 (Pubitemid 34106413)
    • (2002) Cancer Research , vol.62 , Issue.2 , pp. 409-416
    • Jonsson, M.1    Dejmek, J.2    Bendahl, P.-O.3    Andersson, T.4
  • 49
    • 39849098719 scopus 로고    scopus 로고
    • Sonic Hedgehog regulates Hes1 through a novel mechanism that is independent of canonical Notch pathway signalling
    • DOI 10.1038/sj.onc.1210767, PII 1210767
    • Ingram W. J., McCue K. I., Tran T. H., Hallahan A. R., Wainwright B. J., Sonic Hedgehog regulates Hes1 through a novel mechanism that is independent of canonical Notch pathway signalling Oncogene 2008 27 10 1489 1500 (Pubitemid 351317457)
    • (2008) Oncogene , vol.27 , Issue.10 , pp. 1489-1500
    • Ingram, W.J.1    McCue, K.I.2    Tran, T.H.3    Hallahan, A.R.4    Wainwright, B.J.5
  • 50
    • 78650355900 scopus 로고    scopus 로고
    • The Notch target Hes1 directly modulates Gli1 expression and hedgehog signaling: A potential mechanism of therapeutic resistance
    • Schreck K. C., Taylor P., Marchionni L., Gopalakrishnan V., Bar E. E., Gaiano N., Eberhart C. G., The Notch target Hes1 directly modulates Gli1 expression and hedgehog signaling: a potential mechanism of therapeutic resistance Clinical Cancer Research 2010 16 24 6060 6070
    • (2010) Clinical Cancer Research , vol.16 , Issue.24 , pp. 6060-6070
    • Schreck, K.C.1    Taylor, P.2    Marchionni, L.3    Gopalakrishnan, V.4    Bar, E.E.5    Gaiano, N.6    Eberhart, C.G.7
  • 51
    • 33746765208 scopus 로고    scopus 로고
    • Notch ligand, JAG1, is evolutionarily conserved target of canonical WNT signaling pathway in progenitor cells
    • Katoh M., Katoh M., Notch ligand, JAG1, is evolutionarily conserved target of canonical WNT signaling pathway in progenitor cells International Journal of Molecular Medicine 2006 17 4 681 685
    • (2006) International Journal of Molecular Medicine , vol.17 , Issue.4 , pp. 681-685
    • Katoh, M.1    Katoh, M.2
  • 53
    • 0041856097 scopus 로고    scopus 로고
    • Phosphorylation by glycogen synthase kinase-3β down-regulates Notch activity, a link for Notch and Wnt pathways
    • DOI 10.1074/jbc.M304001200
    • Espinosa L., Inglés-Esteve J., Aguilera C., Bigas A., Phosphorylation by glycogen synthase kinase-3 down-regulates Notch activity, a link for Notch and Wnt pathways Journal of Biological Chemistry 2003 278 34 32227 32235 (Pubitemid 37048415)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.34 , pp. 32227-32235
    • Espinosa, L.1    Ingles-Esteve, J.2    Aguilera, C.3    Bigas, A.4
  • 54
    • 0029670476 scopus 로고    scopus 로고
    • Interaction between wingless and notch signaling pathways mediated by dishevelled
    • Axelrod J. D., Matsuno K., Artavanis-Tsakonas S., Perrimon N., Interaction between wingless and notch signaling pathways mediated by dishevelled Science 1996 271 5257 1826 1832
    • (1996) Science , vol.271 , Issue.5257 , pp. 1826-1832
    • Axelrod, J.D.1    Matsuno, K.2    Artavanis-Tsakonas, S.3    Perrimon, N.4
  • 56
    • 33947114865 scopus 로고    scopus 로고
    • Inhibitory Gli3 Activity Negatively Regulates Wnt/β-Catenin Signaling
    • DOI 10.1016/j.cub.2007.01.062, PII S0960982207009323
    • Ulloa F., Itasaki N., Briscoe J., Inhibitory Gli3 activity negatively regulates Wnt/beta-catenin signaling Current Biology 2007 17 6 545 550 (Pubitemid 46401379)
    • (2007) Current Biology , vol.17 , Issue.6 , pp. 545-550
    • Ulloa, F.1    Itasaki, N.2    Briscoe, J.3
  • 58
    • 75649088945 scopus 로고    scopus 로고
    • Contrasting activity of Hedgehog and Wnt pathways according to gastric cancer cell differentiation: Relevance of crosstalk mechanisms
    • Kim J. H., Shin H. S., Lee S. H., Lee I., Lee Y. S., Park J. C., Kim Y. J., Chung J. B., Lee Y. C., Contrasting activity of Hedgehog and Wnt pathways according to gastric cancer cell differentiation: relevance of crosstalk mechanisms Cancer Science 2010 101 2 328 335
    • (2010) Cancer Science , vol.101 , Issue.2 , pp. 328-335
    • Kim, J.H.1    Shin, H.S.2    Lee, S.H.3    Lee, I.4    Lee, Y.S.5    Park, J.C.6    Kim, Y.J.7    Chung, J.B.8    Lee, Y.C.9
  • 59
    • 84855888693 scopus 로고    scopus 로고
    • Hedgehog signaling pathway as a therapeutic target in various types of cancer
    • Onishi H., Katano M., Hedgehog signaling pathway as a therapeutic target in various types of cancer Cancer Science 2011 102 10 1756 1760
    • (2011) Cancer Science , vol.102 , Issue.10 , pp. 1756-1760
    • Onishi, H.1    Katano, M.2


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