-
1
-
-
0017167185
-
Clonal evolution of tumor-cell populations
-
Nowell PC. Clonal evolution of tumor-cell populations. Science. 1976;194(4260):23-28.
-
(1976)
Science
, vol.194
, Issue.4260
, pp. 23-28
-
-
Nowell, P.C.1
-
2
-
-
0031004175
-
Genetic instability in colorectal cancers
-
DOI 10.1038/386623a0
-
Lengauer C, Kinzler KW, Vogelstein B. Genetic instability in colorectal cancers. Nature. 1997; 386(6625):623-627. (Pubitemid 27175430)
-
(1997)
Nature
, vol.386
, Issue.6625
, pp. 623-627
-
-
Lengauer, C.1
Kinzler, K.W.2
Vogelstein, B.3
-
3
-
-
0032542364
-
Genetic instabilities in human cancers
-
DOI 10.1038/25292
-
Lengauer C, Kinzler KW, Vogelstein B. Genetic instabilities in human cancers. Nature. 1998; 396(6712):643-649. (Pubitemid 29003936)
-
(1998)
Nature
, vol.396
, Issue.6712
, pp. 643-649
-
-
Lengauer, C.1
Kinzler, K.W.2
Vogelstein, B.3
-
4
-
-
51649083703
-
Merotelic kinetochore orientation, aneuploidy, and cancer
-
Cimini D. Merotelic kinetochore orientation, aneuploidy, and cancer. Biochim Biophys Acta. 2008; 1786(1):32-40.
-
(2008)
Biochim Biophys Acta
, vol.1786
, Issue.1
, pp. 32-40
-
-
Cimini, D.1
-
5
-
-
40849096242
-
Examining the link between chromosomal instability and aneuploidy in human cells
-
DOI 10.1083/jcb.200712029
-
Thompson SL, Compton DA. Examining the link between chromosomal instability and aneuploidy in human cells. J Cell Biol. 2008;180(4):665-672. (Pubitemid 351397764)
-
(2008)
Journal of Cell Biology
, vol.180
, Issue.4
, pp. 665-672
-
-
Thompson, S.L.1
Compton, D.A.2
-
6
-
-
74049135504
-
Concerning the origin of malignant tumours by Theodor Boveri. Translated and annotated by Henry Harris
-
Boveri T. Concerning the origin of malignant tumours by Theodor Boveri. Translated and annotated by Henry Harris. J Cell Sci. 2008;121 suppl 1:1-84.
-
(2008)
J Cell Sci
, vol.121
, Issue.SUPPL. 1
, pp. 1-84
-
-
Boveri, T.1
-
7
-
-
9644252828
-
Trisomy 4 associated with double minute chromosomes and MYC amplification in acute myeloblastic leukemia
-
DOI 10.1016/j.anngen.2004.08.004, PII S0003399504000784
-
Receveur A, et al. Trisomy 4 associated with double minute chromosomes and MYC amplification in acute myeloblastic leukemia. Ann Genet. 2004; 47(4):423-427. (Pubitemid 39575623)
-
(2004)
Annales de Genetique
, vol.47
, Issue.4
, pp. 423-427
-
-
Receveur, A.1
Ong, J.2
Merlin, L.3
Azgui, Z.4
Merle-Bral, H.5
Berger, R.6
Nguyen-Khac, F.7
-
8
-
-
0032188805
-
The importance of diagnostic cytogenetics on outcome in AML: Analysis of 1,612 patients entered into the MRC AML 10 trial
-
Goldstone A, et al. The importance of diagnostic cytogenetics on outcome in AML: Analysis of 1,612 patients entered into the MRC AML 10 trial. Blood. 1998;92(7):2322-2333. (Pubitemid 28452973)
-
(1998)
Blood
, vol.92
, Issue.7
, pp. 2322-2333
-
-
Grimwade, D.1
Walker, H.2
Oliver, F.3
Wheatley, K.4
Harrison, C.5
Harrison, G.6
Rees, J.7
Hann, I.8
Stevens, R.9
Burnett, A.10
Goldstone, A.11
-
9
-
-
0000082786
-
Hierarchical cytogenetic classification is highly predictive of outcome in AML arising at all ages: Analysis of 4225 cases entered in the UK MRC leukaemia trials
-
Grimwade D, et al. Hierarchical cytogenetic classification is highly predictive of outcome in AML arising at all ages: Analysis of 4225 cases entered in the UK MRC leukaemia trials. Blood. 2000;96:825a.
-
(2000)
Blood
, vol.96
-
-
Grimwade, D.1
-
10
-
-
77349083266
-
Genetic tests to evaluate prognosis and predict therapeutic response in acute myeloid leukemia
-
Gulley ML, Shea TC, Fedoriw Y. Genetic tests to evaluate prognosis and predict therapeutic response in acute myeloid leukemia. J Mol Diagn. 2010; 12(1):3-16.
-
(2010)
J Mol Diagn
, vol.12
, Issue.1
, pp. 3-16
-
-
Gulley, M.L.1
Shea, T.C.2
Fedoriw, Y.3
-
11
-
-
15744373806
-
Chromosome 7 abnormalities in acute megakaryoblastic leukemia associated with Down syndrome
-
DOI 10.1016/j.cancergencyto.2004.08.036
-
Kobayashi K, Usami I, Kubota M, Nishio T, Kakazu N. Chromosome 7 abnormalities in acute megakaryoblastic leukemia associated with Down syndrome. Cancer Genet Cytogenet. 2005;158(2):184-187. (Pubitemid 40417702)
-
(2005)
Cancer Genetics and Cytogenetics
, vol.158
, Issue.2
, pp. 184-187
-
-
Kobayashi, K.-I.1
Usami, I.2
Kubota, M.3
Nishio, T.4
Kakazu, N.5
-
12
-
-
33846667372
-
The profile and incidence of cancer in Down syndrome
-
DOI 10.1111/j.1365-2788.2006.00862.x
-
Sullivan SG, Hussain R, Glasson EJ, Bittles AH. The profile and incidence of cancer in Down syndrome. J Intellect Disabil Res. 2007;51(pt 3):228-231. (Pubitemid 46189568)
-
(2007)
Journal of Intellectual Disability Research
, vol.51
, Issue.3
, pp. 228-231
-
-
Sullivan, S.G.1
Hussain, R.2
Glasson, E.J.3
Bittles, A.H.4
-
13
-
-
33644872564
-
Cancer incidence of persons with Down syndrome in Finland: A population-based study
-
DOI 10.1002/ijc.21518
-
Patja K, Pukkala E, Sund R, Iivanainen M, Kaski M. Cancer incidence of persons with Down syndrome in Finland: A population-based study. Int J Cancer. 2006;118(7):1769-1772. (Pubitemid 43376441)
-
(2006)
International Journal of Cancer
, vol.118
, Issue.7
, pp. 1769-1772
-
-
Patja, K.1
Pukkala, E.2
Sund, R.3
Iivanainen, M.4
Kaski, M.5
-
14
-
-
0042266900
-
High risk of malignancy in mosaic variegated aneuploidy syndrome [6]
-
Hunter A. High risk of malignancy in mosaic variegated aneuploidy syndrome. Am J Med Genet A. 2003;117A(2):199. (Pubitemid 37064020)
-
(2003)
American Journal of Medical Genetics
, vol.117 A
, Issue.2
, pp. 199
-
-
Hunter, A.1
-
15
-
-
0037089953
-
High risk of malignancy in mosaic variegated aneuploidy syndrome
-
DOI 10.1002/ajmg.10281
-
Jacquemont S, Boceno M, Rival JM, Mechinaud F, David A. High risk of malignancy in mosaic variegated aneuploidy syndrome. Am J Med Genet. 2002;109(1):17-21. (Pubitemid 34259949)
-
(2002)
American Journal of Medical Genetics
, vol.109
, Issue.1
, pp. 17-21
-
-
Jacquemont, S.1
Boceno, M.2
Rival, J.M.3
Mechinaud, F.4
David, A.5
-
16
-
-
10644258336
-
Constitutional aneuploidy and cancer predisposition caused by biallelic mutations in BUB1B
-
DOI 10.1038/ng1449
-
Rahman N, et al. Constitutional aneuploidy and cancer predisposition caused by biallelic mutations in BUB1B. Nat Genet. 2004;36(11):1159-1161. (Pubitemid 41288963)
-
(2004)
Nature Genetics
, vol.36
, Issue.11
, pp. 1159-1161
-
-
Hanks, S.1
Coleman, K.2
Reid, S.3
Plaja, A.4
Firth, H.5
FitzPatrick, D.6
Kidd, A.7
Mehes, K.8
Nash, R.9
Robin, N.10
Shannon, N.11
Tolmie, J.12
Swansbury, J.13
Irrthum, A.14
Douglas, J.15
Rahman, N.16
-
17
-
-
33846853947
-
Trisomy 8 as the sole chromosomal aberration in acute myeloid leukemia and myelodysplastic syndromes
-
DOI 10.1016/j.patbio.2006.04.007, PII S036981140600068X
-
Paulsson K, Johansson B. Trisomy 8 as the sole chromosomal aberration in acute myeloid leukemia and myelodysplastic syndromes. Pathol Biol (Paris). 2007;55(1):37-48. (Pubitemid 46217945)
-
(2007)
Pathologie Biologie
, vol.55
, Issue.1
, pp. 37-48
-
-
Paulsson, K.1
Johansson, B.2
-
18
-
-
0033782853
-
Spindle assembly in animal cells
-
Compton DA. Spindle assembly in animal cells. Annu Rev Biochem. 2000;69:95-114.
-
(2000)
Annu Rev Biochem
, vol.69
, pp. 95-114
-
-
Compton, D.A.1
-
19
-
-
10944236258
-
The dynamic kinetochore-microtubule interface
-
DOI 10.1242/jcs.01536
-
Maiato H, DeLuca J, Salmon ED, Earnshaw WC. The dynamic kinetochore-microtubule interface. J Cell Sci. 2004;117(pt 23):5461-5477. (Pubitemid 40012194)
-
(2004)
Journal of Cell Science
, vol.117
, Issue.23
, pp. 5461-5477
-
-
Maiato, H.1
DeLuca, J.2
Salmon, E.D.3
Earnshaw, W.C.4
-
21
-
-
51349147655
-
Overexpression of Separase induces aneuploidy and mammary tumorigenesis
-
Pati D, et al. Overexpression of Separase induces aneuploidy and mammary tumorigenesis. Proc Natl Acad Sci U S A. 2008;105(35):13033-13038.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, Issue.35
, pp. 13033-13038
-
-
Pati, D.1
-
22
-
-
38349169905
-
Simultaneous Aurora-A/STK15 overexpression and centrosome amplification induce chromosomal instability in tumour cells with a MIN phenotype
-
Di Leonardo A, Lentini L, Amato A, Schillaci T. Simultaneous Aurora-A/STK15 overexpression and centrosome amplification induce chromosomal instability in tumour cells with a MIN phenotype. BMC Cancer. 2007;7:212.
-
(2007)
BMC Cancer
, vol.7
, pp. 212
-
-
Di Leonardo, A.1
Lentini, L.2
Amato, A.3
Schillaci, T.4
-
23
-
-
68749084849
-
Multipolar spindle pole coalescence is a major source of kinetochore mis-attachment and chromosome mis-segregation in cancer cells
-
Silkworth WT, Nardi IK, Scholl LM, Cimini D. Multipolar spindle pole coalescence is a major source of kinetochore mis-attachment and chromosome mis-segregation in cancer cells. PloS One. 2009; 4(8):e6564.
-
(2009)
PloS One
, vol.4
, Issue.8
-
-
Silkworth, W.T.1
Nardi, I.K.2
Scholl, L.M.3
Cimini, D.4
-
24
-
-
67649467032
-
A mechanism linking extra centrosomes to chromosomal instability
-
Ganem NJ, Godinho SA, Pellman D. A mechanism linking extra centrosomes to chromosomal instability. Nature. 2009;460(7252):278-282.
-
(2009)
Nature
, vol.460
, Issue.7252
, pp. 278-282
-
-
Ganem, N.J.1
Godinho, S.A.2
Pellman, D.3
-
25
-
-
78649730181
-
Different outcomes of telomere-dependent anaphase bridges
-
Tusell L, Pampalona J, Soler D, Frias C, Genesca A. Different outcomes of telomere-dependent anaphase bridges. Biochem Soc Trans. 2010;38(6):1698-1703.
-
(2010)
Biochem Soc Trans
, vol.38
, Issue.6
, pp. 1698-1703
-
-
Tusell, L.1
Pampalona, J.2
Soler, D.3
Frias, C.4
Genesca, A.5
-
26
-
-
0032546360
-
Mutations of mitotic checkpoint genes in human cancers
-
DOI 10.1038/32688
-
Cahill DP, et al. Mutations of mitotic check-point genes in human cancers. Nature. 1998; 392(6673):300-303. (Pubitemid 28155105)
-
(1998)
Nature
, vol.392
, Issue.6673
, pp. 300-303
-
-
Cahill, D.P.1
Lengauer, C.2
Yu, J.3
Riggins, G.J.4
Willson, J.K.V.5
Markowitz, S.D.6
Kinzler, K.W.7
Vogelstein, B.8
-
27
-
-
77949773695
-
Mad2-induced chromosome instability leads to lung tumour relapse after oncogene withdrawal
-
Sotillo R, Schvartzman JM, Socci ND, Benezra R. Mad2-induced chromosome instability leads to lung tumour relapse after oncogene withdrawal. Nature. 2010;464(7287):436-440.
-
(2010)
Nature
, vol.464
, Issue.7287
, pp. 436-440
-
-
Sotillo, R.1
Schvartzman, J.M.2
Socci, N.D.3
Benezra, R.4
-
28
-
-
55949096605
-
Hec1 overexpression hyperactivates the mitotic checkpoint and induces tumor formation in vivo
-
Diaz-Rodriguez E, Sotillo R, Schvartzman JM, Benezra R. Hec1 overexpression hyperactivates the mitotic checkpoint and induces tumor formation in vivo. Proc Natl Acad Sci U S A. 2008;105(43):16719-16724.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, Issue.43
, pp. 16719-16724
-
-
Diaz-Rodriguez, E.1
Sotillo, R.2
Schvartzman, J.M.3
Benezra, R.4
-
29
-
-
58149334818
-
Genome stability is ensured by temporal control of kinetochore- microtubule dynamics
-
Bakhoum SF, Thompson SL, Manning AL, Compton DA. Genome stability is ensured by temporal control of kinetochore-microtubule dynamics. Nat Cell Biol. 2009;11(1):27-35.
-
(2009)
Nat Cell Biol
, vol.11
, Issue.1
, pp. 27-35
-
-
Bakhoum, S.F.1
Thompson, S.L.2
Manning, A.L.3
Compton, D.A.4
-
30
-
-
70450176266
-
Deviant kinetochore microtubule dynamics underlie chromosomal instability
-
Bakhoum SF, Genovese G, Compton DA. Deviant kinetochore microtubule dynamics underlie chromosomal instability. Curr Biol. 2009; 19(22):1937-1942.
-
(2009)
Curr Biol
, vol.19
, Issue.22
, pp. 1937-1942
-
-
Bakhoum, S.F.1
Genovese, G.2
Compton, D.A.3
-
31
-
-
84055163537
-
Merotelic attachment of single kinetochores to microtubules from opposite poles is not detected by the mitotic spindle checkpoint and induces chromosome loss during mitosis
-
Cimini D, Howell BJ, Degrassi F, Salmon ED. Merotelic attachment of single kinetochores to microtubules from opposite poles is not detected by the mitotic spindle checkpoint and induces chromosome loss during mitosis. Mol Biol Cell. 2000; 11:430a.
-
(2000)
Mol Biol Cell
, vol.11
-
-
Cimini, D.1
Howell, B.J.2
Degrassi, F.3
Salmon, E.D.4
-
32
-
-
0035972237
-
Merotelic kinetochore orientation is a major mechanism of aneuploidy in mitotic mammalian tissue cells
-
Cimini D, Howell B, Maddox P, Khodjakov A, Degrassi F, Salmon ED. Merotelic kinetochore orientation is a major mechanism of aneuploidy in mitotic mammalian tissue cells. J Cell Biol. 2001; 153(3):517-527. (Pubitemid 34280139)
-
(2001)
Journal of Cell Biology
, vol.152
, Issue.3
, pp. 517-527
-
-
Cimini, D.1
Howell, B.2
Maddox, P.3
Khodjakov, A.4
Degrassi, F.5
Salmon, E.D.6
-
33
-
-
80051985198
-
The spatial arrangement of chromosomes during prometaphase facilitates spindle assembly
-
Khodjakov A, Magidson V, O'Connell CB, Loncarek J, Paul R, Mogilner A. The spatial arrangement of chromosomes during prometaphase facilitates spindle assembly. Cell. 2011;146(4):555-567.
-
(2011)
Cell
, vol.146
, Issue.4
, pp. 555-567
-
-
Khodjakov, A.1
Magidson, V.2
O'Connell, C.B.3
Loncarek, J.4
Paul, R.5
Mogilner, A.6
-
34
-
-
31144471300
-
Chromosomes can congress to the metaphase plate before biorientation
-
DOI 10.1126/science.1122142
-
Kapoor TM, et al. Chromosomes can congress to the metaphase plate before biorientation. Science. 2006;311(5759):388-391. (Pubitemid 43132665)
-
(2006)
Science
, vol.311
, Issue.5759
, pp. 388-391
-
-
Kapoor, T.M.1
Lampson, M.A.2
Hergert, P.3
Cameron, L.4
Cimini, D.5
Salmon, E.D.6
McEwen, B.F.7
Khodjakov, A.8
-
35
-
-
36749005585
-
The centromere geometry essential for keeping mitosis error free is controlled by spindle forces
-
DOI 10.1038/nature06344, PII NATURE06344
-
Loncarek J, et al. The centromere geometry essential for keeping mitosis error free is controlled by spindle forces. Nature. 2007;450(7170):745-749. (Pubitemid 350207690)
-
(2007)
Nature
, vol.450
, Issue.7170
, pp. 745-749
-
-
Loncarek, J.1
Kisurina-Evgenieva, O.2
Vinogradova, T.3
Hergert, P.4
La, T.S.5
Kapoor, T.M.6
Khodjakov, A.7
-
36
-
-
37549071893
-
Molecular architecture of the kinetochore-microtubule interface
-
Cheeseman IM, Desai A. Molecular architecture of the kinetochore- microtubule interface. Nat Rev Mol Cell Biol. 2008;9(1):33-46.
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, Issue.1
, pp. 33-46
-
-
Cheeseman, I.M.1
Desai, A.2
-
38
-
-
33751227843
-
Kinetochore Microtubule Dynamics and Attachment Stability Are Regulated by Hec1
-
DOI 10.1016/j.cell.2006.09.047, PII S0092867406014085
-
DeLuca JG, Gall WE, Ciferri C, Cimini D, Musacchio A, Salmon ED. Kinetochore microtubule dynamics and attachment stability are regulated by Hec1. Cell. 2006;127(5):969-982. (Pubitemid 44792254)
-
(2006)
Cell
, vol.127
, Issue.5
, pp. 969-982
-
-
DeLuca, J.G.1
Gall, W.E.2
Ciferri, C.3
Cimini, D.4
Musacchio, A.5
Salmon, E.D.6
-
39
-
-
68249133956
-
Cancer: CINful centrosomes
-
Bakhoum SF, Compton DA. Cancer: CINful centrosomes. Curr Biol. 2009;19(15):R642-R645.
-
(2009)
Curr Biol
, vol.19
, Issue.15
-
-
Bakhoum, S.F.1
Compton, D.A.2
-
40
-
-
33847625012
-
Overexpression of BUBR1 is associated with chromosomal instability in bladder cancer
-
DOI 10.1016/j.cancergencyto.2006.11.012, PII S0165460806007758
-
Sasaki K, et al. Overexpression of BUBR1 is associated with chromosomal instability in bladder cancer. Cancer Genet Cytogenet. 2007;174(1):42-47. (Pubitemid 46365984)
-
(2007)
Cancer Genetics and Cytogenetics
, vol.174
, Issue.1
, pp. 42-47
-
-
Yamamoto, Y.1
Matsuyama, H.2
Chochi, Y.3
Okuda, M.4
Kawauchi, S.5
Inoue, R.6
Furuya, T.7
Oga, A.8
Naito, K.9
Sasaki, K.10
-
41
-
-
0035905811
-
MAD2 haplo-insufficiency causes premature anaphase and chromosome instability in mammalian cells
-
DOI 10.1038/35053094
-
Michel LS, et al. MAD2 haplo-insufficiency causes premature anaphase and chromosome instability in mammalian cells. Nature. 2001;409(6818):355-359. (Pubitemid 32151241)
-
(2001)
Nature
, vol.409
, Issue.6818
, pp. 355-359
-
-
Michel, L.S.1
Liberal, V.2
Chatterjee, A.3
Kirchwegger, R.4
Pasche, B.5
Gerald, W.6
Dobles, M.7
Sorger, P.K.8
Murty, V.V.V.S.9
Benezra, R.10
-
42
-
-
12344266713
-
The human mitotic checkpoint protein BubR1 regulates chromosome-spindle attachments
-
DOI 10.1038/ncb1208
-
Lampson MA, Kapoor TM. The human mitotic checkpoint protein BubR1 regulates chromosome-spindle attachments. Nat Cell Biol. 2005;7(1):93-98. (Pubitemid 40123388)
-
(2005)
Nature Cell Biology
, vol.7
, Issue.1
, pp. 93-98
-
-
Lampson, M.A.1
Kapoor, T.M.2
-
43
-
-
34247333444
-
The spindle-assembly checkpoint in space and time
-
DOI 10.1038/nrm2163, PII NRM2163
-
Musacchio A, Salmon ED. The spindle-assembly checkpoint in space and time. Nat Rev Mol Cell Biol. 2007;8(5):379-393. (Pubitemid 46643240)
-
(2007)
Nature Reviews Molecular Cell Biology
, vol.8
, Issue.5
, pp. 379-393
-
-
Musacchio, A.1
Salmon, E.D.2
-
44
-
-
77958478983
-
CLASP1, astrin and Kif2b form a molecular switch that regulates kinetochore-microtubule dynamics to promote mitotic progression and fidelity
-
Manning AL, Bakhoum SF, Maffini S, Correia- Melo C, Maiato H, Compton DA. CLASP1, astrin and Kif2b form a molecular switch that regulates kinetochore-microtubule dynamics to promote mitotic progression and fidelity. EMBO J. 2010; 29(20):3531-3543.
-
(2010)
EMBO J
, vol.29
, Issue.20
, pp. 3531-3543
-
-
Manning, A.L.1
Bakhoum, S.F.2
Maffini, S.3
Correia- Melo, C.4
Maiato, H.5
Compton, D.A.6
-
45
-
-
27144507868
-
Cytokinesis failure generating tetraploids promotes tumorigenesis in p53-null cells
-
DOI 10.1038/nature04217, PII N04217
-
Fujiwara T, Bandi M, Nitta M, Ivanova EV, Bronson RT, Pellman D. Cytokinesis failure generating tetraploids promotes tumorigenesis in p53-null cells. Nature. 2005;437(7061):1043-1047. (Pubitemid 41486987)
-
(2005)
Nature
, vol.437
, Issue.7061
, pp. 1043-1047
-
-
Fujiwara, T.1
Bandi, M.2
Nitta, M.3
Ivanova, E.V.4
Bronson, R.T.5
Pellman, D.6
-
46
-
-
78650959663
-
Massive genomic rearrangement acquired in a single catastrophic event during cancer development
-
Campbell PJ, et al. Massive genomic rearrangement acquired in a single catastrophic event during cancer development. Cell. 2011;144(1):27-40.
-
(2011)
Cell
, vol.144
, Issue.1
, pp. 27-40
-
-
Campbell, P.J.1
-
47
-
-
78650964769
-
Cancer genomes evolve by pulverizing single chromosomes
-
Meyerson M, Pellman D. Cancer genomes evolve by pulverizing single chromosomes. Cell. 2011;144(1):9-10.
-
(2011)
Cell
, vol.144
, Issue.1
, pp. 9-10
-
-
Meyerson, M.1
Pellman, D.2
-
48
-
-
84055176499
-
Chromosomal instability substantiates poor prognosis in patients with diffuse large B-cell lymphoma
-
Bakhoum SF, Danilova OV, Kaur P, Levy NB, Compton DA. Chromosomal instability substantiates poor prognosis in patients with diffuse large B-cell lymphoma. Clin Cancer Res. 2011;17(24):7704-7711.
-
(2011)
Clin Cancer Res
, vol.17
, Issue.24
, pp. 7704-7711
-
-
Bakhoum, S.F.1
Danilova, O.V.2
Kaur, P.3
Levy, N.B.4
Compton, D.A.5
-
49
-
-
77955479205
-
-
Web site. Updated November 21, 2011. Accessed February 13, 2012
-
Mitelman F, Johansson B, Mertens F, eds. Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer. NIH Web site. http://cgap. nci.nih.gov/Chromosomes/Mitelman. Updated November 21, 2011. Accessed February 13, 2012.
-
Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer
-
-
Mitelman, F.1
Johansson, B.2
Mertens, F.3
-
50
-
-
46349086833
-
Association between chromosomal instability and prognosis in colorectal cancer: A meta-analysis
-
DOI 10.1136/gut.2007.135004
-
Walther A, Houlston R, Tomlinson I. Association between chromosomal instability and prognosis in colorectal cancer: a meta-analysis. Gut. 2008;57(7):941-950. (Pubitemid 351919529)
-
(2008)
Gut
, vol.57
, Issue.7
, pp. 941-950
-
-
Walther, A.1
Houlston, R.2
Tomlinson, I.3
-
51
-
-
41849120477
-
Chromosomal instability in bladder cancer
-
Florl AR, Schulz WA. Chromosomal instability in bladder cancer. Arch Toxicol. 2008;82(3):173-182.
-
(2008)
Arch Toxicol
, vol.82
, Issue.3
, pp. 173-182
-
-
Florl, A.R.1
Schulz, W.A.2
-
52
-
-
77951962238
-
JC human polyomavirus is associated to chromosomal instability in peripheral blood lymphocytes of Hodgkin's lymphoma patients and poor clinical outcome
-
M'kacher R, et al. JC human polyomavirus is associated to chromosomal instability in peripheral blood lymphocytes of Hodgkin's lymphoma patients and poor clinical outcome. Ann Oncol. 2010; 21(4):826-832.
-
(2010)
Ann Oncol
, vol.21
, Issue.4
, pp. 826-832
-
-
M'kacher, R.1
-
53
-
-
34548548519
-
Chromosomal instability and supernumerary centrosomes represent precursor defects in a mouse model of T-cell lymphoma
-
DOI 10.1158/0008-5472.CAN-07-1666
-
Knudson CM, van de Wetering CI. Chromosomal instability and supernumerary centrosomes represent precursor defects in a mouse model of T-cell lymphoma. Cancer Res. 2007;67(17):8081-8088. (Pubitemid 47395142)
-
(2007)
Cancer Research
, vol.67
, Issue.17
, pp. 8081-8088
-
-
Van De, W.C.I.1
Knudson, C.M.2
-
54
-
-
10744221244
-
Centrosome aberrations as a possible mechanism for chromosomal instability in non-Hodgkin's lymphoma
-
DOI 10.1038/sj.leu.2403142
-
Kramer A, et al. Centrosome aberrations as a possible mechanism for chromosomal instability in non-Hodgkin's lymphoma. Leukemia. 2003; 17(11):2207-2213. (Pubitemid 37428388)
-
(2003)
Leukemia
, vol.17
, Issue.11
, pp. 2207-2213
-
-
Kramer, A.1
Schweizer, S.2
Neben, K.3
Giesecke, C.4
Kalla, J.5
Katzenberger, T.6
Benner, A.7
Muller-Hermelink, H.K.8
Ho, A.D.9
Ott, G.10
-
55
-
-
75149140916
-
Mitotic chromosomal instability and cancer: Mouse modelling of the human disease
-
Schvartzman JM, Sotillo R, Benezra R. Mitotic chromosomal instability and cancer: mouse modelling of the human disease. Nat Rev Cancer. 2010; 10(2):102-115.
-
(2010)
Nat Rev Cancer
, vol.10
, Issue.2
, pp. 102-115
-
-
Schvartzman, J.M.1
Sotillo, R.2
Benezra, R.3
-
56
-
-
33846065784
-
Aneuploidy Acts Both Oncogenically and as a Tumor Suppressor
-
DOI 10.1016/j.ccr.2006.12.003, PII S1535610806003680
-
Weaver BA, Silk AD, Montagna C, Verdier-Pinard P, Cleveland DW. Aneuploidy acts both oncogenically and as a tumor suppressor. Cancer Cell. 2007; 11(1):25-36. (Pubitemid 46070223)
-
(2007)
Cancer Cell
, vol.11
, Issue.1
, pp. 25-36
-
-
Weaver, B.A.A.1
Silk, A.D.2
Montagna, C.3
Verdier-Pinard, P.4
Cleveland, D.W.5
-
57
-
-
79958733630
-
Mad2 is a critical mediator of the chromosome instability observed upon Rb and p53 pathway inhibition
-
Schvartzman JM, Duijf PH, Sotillo R, Coker C, Benezra R. Mad2 is a critical mediator of the chromosome instability observed upon Rb and p53 pathway inhibition. Cancer Cell. 2011;19(6):701-714.
-
(2011)
Cancer Cell
, vol.19
, Issue.6
, pp. 701-714
-
-
Schvartzman, J.M.1
Duijf, P.H.2
Sotillo, R.3
Coker, C.4
Benezra, R.5
-
58
-
-
76349126361
-
Proliferation of aneuploid human cells is limited by a p53-dependent mechanism
-
Thompson SL, Compton DA. Proliferation of aneuploid human cells is limited by a p53-dependent mechanism. J Cell Biol. 2010;188(3):369-381.
-
(2010)
J Cell Biol
, vol.188
, Issue.3
, pp. 369-381
-
-
Thompson, S.L.1
Compton, D.A.2
-
59
-
-
77955138739
-
Transcriptomic profiling of human oocytes: Association of meiotic aneuploidy and altered oocyte gene expression
-
Fragouli E, et al. Transcriptomic profiling of human oocytes: association of meiotic aneuploidy and altered oocyte gene expression. Mol Hum Reprod. 2010;16(8):570-582.
-
(2010)
Mol Hum Reprod
, vol.16
, Issue.8
, pp. 570-582
-
-
Fragouli, E.1
-
60
-
-
3543110316
-
Transcript level alterations reflect gene dosage effects across multiple tissues in a mouse model of down syndrome
-
Yaspo ML, et al. Transcript level alterations reflect gene dosage effects across multiple tissues in a mouse model of down syndrome. Genome Res. 2004; 14(7):1258-1267.
-
(2004)
Genome Res
, vol.14
, Issue.7
, pp. 1258-1267
-
-
Yaspo, M.L.1
-
61
-
-
70749158525
-
Whole chromosome instability caused by Bub1 insufficiency drives tumorigenesis through tumor suppressor gene loss of heterozygosity
-
Baker DJ, Jin F, Jeganathan KB, van Deursen JM. Whole chromosome instability caused by Bub1 insufficiency drives tumorigenesis through tumor suppressor gene loss of heterozygosity. Cancer Cell. 2009;16(6):475-486.
-
(2009)
Cancer Cell
, vol.16
, Issue.6
, pp. 475-486
-
-
Baker, D.J.1
Jin, F.2
Jeganathan, K.B.3
Van Deursen, J.M.4
-
62
-
-
80053364894
-
Chromosome segregation errors as a cause of DNA damage and structural chromosome aberrations
-
Janssen A, van der Burg M, Szuhai K, Kops GJPL, Medema RH. Chromosome segregation errors as a cause of DNA damage and structural chromosome aberrations. Science. 2011;333(6051):1895-1898.
-
(2011)
Science
, vol.333
, Issue.6051
, pp. 1895-1898
-
-
Janssen, A.1
Van Der Burg, M.2
Szuhai, K.3
Kops, G.J.P.L.4
Medema, R.H.5
-
63
-
-
56849125516
-
The aneuploidy paradox in cell growth and tumorigenesis
-
Weaver BA, Cleveland DW. The aneuploidy paradox in cell growth and tumorigenesis. Cancer Cell. 2008;14(6):431-433.
-
(2008)
Cancer Cell
, vol.14
, Issue.6
, pp. 431-433
-
-
Weaver, B.A.1
Cleveland, D.W.2
-
64
-
-
73149101630
-
Elevating the frequency of chromosome mis-segregation as a strategy to kill tumor cells
-
Janssen A, Kops GJ, Medema RH. Elevating the frequency of chromosome mis-segregation as a strategy to kill tumor cells. Proc Natl Acad Sci U S A. 2009; 106(45):19108-19113.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, Issue.45
, pp. 19108-19113
-
-
Janssen, A.1
Kops, G.J.2
Medema, R.H.3
-
65
-
-
74949088096
-
Targeting the cyclin E-Cdk-2 complex represses lung cancer growth by triggering anaphase catastrophe
-
Galimberti F, et al. Targeting the cyclin E-Cdk-2 complex represses lung cancer growth by triggering anaphase catastrophe. Clin Cancer Res. 2010; 16(1):109-120.
-
(2010)
Clin Cancer Res
, vol.16
, Issue.1
, pp. 109-120
-
-
Galimberti, F.1
-
66
-
-
15444370589
-
Min/+ compound mutant mice is linked to premature separation of sister chromatids and enhanced genomic instability
-
DOI 10.1073/pnas.0407822102
-
Rao CV, et al. Colonic tumorigenesis in BubR1(+/-) Apc(Min/+) compound mutant mice is linked to premature separation of sister chromatids and enhanced genomic instability. Proc Natl Acad Sci U S A. 2005;102(12):4365-4370. (Pubitemid 40397117)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.12
, pp. 4365-4370
-
-
Rao, C.V.1
Yang, Y.-M.2
Swamy, M.V.3
Liu, T.4
Fang, Y.5
Mahmood, R.6
Jhanwar-Uniyal, M.7
Dai, W.8
-
68
-
-
0032127258
-
Reductive evolution of resident genomes
-
DOI 10.1016/S0966-842X(98)01312-2, PII S0966842X98013122
-
Andersson SGE, Kurland CG. Reductive evolution of resident genomes. Trends Microbiol. 1998; 6(7):263-268. (Pubitemid 28343306)
-
(1998)
Trends in Microbiology
, vol.6
, Issue.7
, pp. 263-268
-
-
Andersson, S.G.E.1
Kurland, C.G.2
-
69
-
-
52449132715
-
Low rates of aneuploidy promote tumorigenesis while high rates of aneuploidy cause cell death and tumor suppression
-
Weaver BA, Silk AD, Cleveland DW. Low rates of aneuploidy promote tumorigenesis while high rates of aneuploidy cause cell death and tumor suppression. Cell Oncol. 2008;30(5):453.
-
(2008)
Cell Oncol
, vol.30
, Issue.5
, pp. 453
-
-
Weaver, B.A.1
Silk, A.D.2
Cleveland, D.W.3
-
70
-
-
79959243434
-
Patterns and incidence of chromosomal instability and their prognostic relevance in breast cancer subtypes
-
Smid M, et al. Patterns and incidence of chromosomal instability and their prognostic relevance in breast cancer subtypes. Breast Cancer Res Treat. 2011; 128(1):23-30.
-
(2011)
Breast Cancer Res Treat
, vol.128
, Issue.1
, pp. 23-30
-
-
Smid, M.1
-
71
-
-
33748286796
-
A signature of chromosomal instability inferred from gene expression profiles predicts clinical outcome in multiple human cancers
-
DOI 10.1038/ng1861, PII NG1861
-
Szallasi Z, Carter SL, Eklund AC, Kohane IS, Harris LN. A signature of chromosomal instability inferred from gene expression profiles predicts clinical outcome in multiple human cancers. Nat Genet. 2006;38(9):1043-1048. (Pubitemid 44325930)
-
(2006)
Nature Genetics
, vol.38
, Issue.9
, pp. 1043-1048
-
-
Carter, S.L.1
Eklund, A.C.2
Kohane, I.S.3
Harris, L.N.4
Szallasi, Z.5
-
72
-
-
78149423336
-
Aneuploidy confers quantitative proteome changes and phenotypic variation in budding yeast
-
Li R, et al. Aneuploidy confers quantitative proteome changes and phenotypic variation in budding yeast. Nature. 2010;468(7321):321-325.
-
(2010)
Nature
, vol.468
, Issue.7321
, pp. 321-325
-
-
Li, R.1
-
73
-
-
78649511384
-
The Aurora-A/TPX2 complex: A novel oncogenic holoenzyme?
-
Guarguaglini G, Asteriti IA, Rensen WM, Lindon C, Lavia P. The Aurora-A/TPX2 complex: A novel oncogenic holoenzyme? Biochim Biophys Acta. 2010; 1806(2):230-239.
-
(2010)
Biochim Biophys Acta
, vol.1806
, Issue.2
, pp. 230-239
-
-
Guarguaglini, G.1
Asteriti, I.A.2
Rensen, W.M.3
Lindon, C.4
Lavia, P.5
-
74
-
-
79956160582
-
Paradoxical relationship between chromosomal instability and survival outcome in cancer
-
Birkbak NJ, et al. Paradoxical relationship between chromosomal instability and survival outcome in cancer. Cancer Res. 2011;71(10):3447-3452.
-
(2011)
Cancer Res
, vol.71
, Issue.10
, pp. 3447-3452
-
-
Birkbak, N.J.1
-
75
-
-
33646262907
-
Diffuse large B-cell lymphoma with overexpression of cyclin E substantiates poor standard treatment response and inferior outcome
-
Tzankov A, et al. Diffuse large B-cell lymphoma with overexpression of cyclin E substantiates poor standard treatment response and inferior outcome. Clin Cancer Res. 2006;12(7 pt 1):2125-2132.
-
(2006)
Clin Cancer Res
, vol.12
, Issue.7 PART 1
, pp. 2125-2132
-
-
Tzankov, A.1
-
76
-
-
33751232957
-
The Conserved KMN Network Constitutes the Core Microtubule-Binding Site of the Kinetochore
-
DOI 10.1016/j.cell.2006.09.039, PII S0092867406013456
-
Cheeseman IM, Chappie JS, Wilson-Kubalek EM, Desai A. The conserved KMN network constitutes the core microtubule-binding site of the kinetochore. Cell. 2006;127(5):983-997. (Pubitemid 44792248)
-
(2006)
Cell
, vol.127
, Issue.5
, pp. 983-997
-
-
Cheeseman, I.M.1
Chappie, J.S.2
Wilson-Kubalek, E.M.3
Desai, A.4
-
77
-
-
33750612373
-
Aurora Kinase Promotes Turnover of Kinetochore Microtubules to Reduce Chromosome Segregation Errors
-
DOI 10.1016/j.cub.2006.07.022, PII S0960982206018537
-
Cimini D, Wan XH, Hirel CB, Salmon ED. Aurora kinase promotes turnover of kinetochore microtubules to reduce chromosome segregation errors. Curr Biol. 2006;16(17):1711-1718. (Pubitemid 44691779)
-
(2006)
Current Biology
, vol.16
, Issue.17
, pp. 1711-1718
-
-
Cimini, D.1
Wan, X.2
Hirel, C.B.3
Salmon, E.D.4
-
78
-
-
62149111407
-
Sensing chromosome bi-orientation by spatial separation of aurora B kinase from kinetochore substrates
-
Liu D, Vader G, Vromans MJ, Lampson MA, Lens SM. Sensing chromosome bi-orientation by spatial separation of aurora B kinase from kinetochore substrates. Science. 2009;323(5919):1350-1353.
-
(2009)
Science
, vol.323
, Issue.5919
, pp. 1350-1353
-
-
Liu, D.1
Vader, G.2
Vromans, M.J.3
Lampson, M.A.4
Lens, S.M.5
-
79
-
-
81155132604
-
AT9283, a novel pan- Aurora/ JAK-2 kinase inhibitor suppresses tumor growth in aggressive B-cell non-Hodgkin's lymphoma
-
abstract
-
Mahadevan D, Liu X, Persky DO, Miller TP, Squires MS, Wenqing Q. AT9283, a novel pan- Aurora/ JAK-2 kinase inhibitor suppresses tumor growth in aggressive B-cell non-Hodgkin's lymphoma [abstract]. Blood. 2010;116:3930.
-
(2010)
Blood
, vol.116
, pp. 3930
-
-
Mahadevan, D.1
Liu, X.2
Persky, D.O.3
Miller, T.P.4
Squires, M.S.5
Wenqing, Q.6
-
80
-
-
79251556865
-
Clinical evaluation of AZD1152, an i.v. inhibitor of Aurora B kinase, in patients with solid malignant tumors
-
Schellens JH, et al. Clinical evaluation of AZD1152, an i.v. inhibitor of Aurora B kinase, in patients with solid malignant tumors. Ann Oncol. 2011; 22(2):431-437.
-
(2011)
Ann Oncol
, vol.22
, Issue.2
, pp. 431-437
-
-
Schellens, J.H.1
-
81
-
-
78649971294
-
Preclinical evaluation of AMG 900, a novel potent and highly selective panaurora kinase inhibitor with activity in taxane- resistant tumor cell lines
-
Payton M, et al. Preclinical evaluation of AMG 900, a novel potent and highly selective panaurora kinase inhibitor with activity in taxane- resistant tumor cell lines. Cancer Res. 2010; 70(23):9846-9854.
-
(2010)
Cancer Res
, vol.70
, Issue.23
, pp. 9846-9854
-
-
Payton, M.1
-
82
-
-
80052100694
-
A Phase I study to assess the safety, pharmacokinetics and efficacy of barasertib (AZD1152), an Aurora B kinase inhibitor, in Japanese patients with advanced acute myeloid leukemia
-
Tsuboi K, et al. A Phase I study to assess the safety, pharmacokinetics and efficacy of barasertib (AZD1152), an Aurora B kinase inhibitor, in Japanese patients with advanced acute myeloid leukemia. Leuk Res. 2011;35(10):1384-1389.
-
(2011)
Leuk Res
, vol.35
, Issue.10
, pp. 1384-1389
-
-
Tsuboi, K.1
-
83
-
-
80053536086
-
Relationship of extreme chromosomal instability with long-term survival in a retrospective analysis of primary breast cancer
-
Roylance R, et al. Relationship of extreme chromosomal instability with long-term survival in a retrospective analysis of primary breast cancer. Cancer Epidemiol Biomarkers Prev. 2011;20(10):2183-2194.
-
(2011)
Cancer Epidemiol Biomarkers Prev
, vol.20
, Issue.10
, pp. 2183-2194
-
-
Roylance, R.1
-
84
-
-
84856424908
-
DNA breaks and chromosome pulverization from errors in mitosis
-
Crasta K, et al. DNA breaks and chromosome pulverization from errors in mitosis. Nature. 2012; 482(7383):53-58.
-
(2012)
Nature
, vol.482
, Issue.7383
, pp. 53-58
-
-
Crasta, K.1
|