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Volumn 2012, Issue , 2012, Pages

Downstream and intermediate interactions of synovial sarcoma-associated fusion oncoproteins and their implication for targeted therapy

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; CANCER TESTIS ANTIGEN; CYCLIN D1; CYCLIN DEPENDENT KINASE INHIBITOR 1A; EARLY GROWTH RESPONSE FACTOR 1; HISTONE DEACETYLASE; HYBRID PROTEIN; ONCOPROTEIN; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN BCL 2; PROTEIN P53; PROTEIN SS18 SSX1; PROTEIN SS18 SSX2; SOMATOMEDIN B; SOMATOMEDIN C RECEPTOR; TRANSCRIPTION FACTOR SNAIL; UNCLASSIFIED DRUG; UVOMORULIN; XRCC4 PROTEIN;

EID: 84859718546     PISSN: 1357714X     EISSN: 13691643     Source Type: Journal    
DOI: 10.1155/2012/249219     Document Type: Review
Times cited : (19)

References (153)
  • 1
    • 0038668852 scopus 로고    scopus 로고
    • Updates on the cytogenetics and molecular genetics of bone and soft tissue tumors: Chondrosarcoma and other cartilaginous neoplasms
    • DOI 10.1016/S0165-4608(03)00002-5
    • Sandberg A. A., Bridge J. A., Updates on the cytogenetics and molecular genetics of bone and soft tissue tumors: chondrosarcoma and other cartilaginous neoplasms Cancer Genetics and Cytogenetics 2003 143 1 1 31 (Pubitemid 36549004)
    • (2003) Cancer Genetics and Cytogenetics , vol.143 , Issue.1 , pp. 1-31
    • Sandberg, A.A.1    Bridge, J.A.2
  • 2
    • 34047155601 scopus 로고    scopus 로고
    • Molecular target therapy for synovial sarcoma
    • Fukukawa C., Nakamura Y., Katagiri T., Molecular target therapy for synovial sarcoma Future Oncology 2005 1 6 805 812
    • (2005) Future Oncology , vol.1 , Issue.6 , pp. 805-812
    • Fukukawa, C.1    Nakamura, Y.2    Katagiri, T.3
  • 4
    • 34047146046 scopus 로고    scopus 로고
    • A Conditional Mouse Model of Synovial Sarcoma: Insights into a Myogenic Origin
    • DOI 10.1016/j.ccr.2007.01.016, PII S1535610807000323
    • Haldar M., Hancock J. D., Coffin C. M., Lessnick S. L., Capecchi M. R., A conditional mouse model of synovial sarcoma: insights into a myogenic origin Cancer Cell 2007 11 4 375 388 (Pubitemid 46518310)
    • (2007) Cancer Cell , vol.11 , Issue.4 , pp. 375-388
    • Haldar, M.1    Hancock, J.D.2    Coffin, C.M.3    Lessnick, S.L.4    Capecchi, M.R.5
  • 6
    • 84878760606 scopus 로고    scopus 로고
    • Reprogramming of mesenchymal stem cells by the synovial sarcoma-associated oncogene SYT-SSX2
    • In press
    • Garcia C. B., Shaffer C. M., Alfaro M. P., Reprogramming of mesenchymal stem cells by the synovial sarcoma-associated oncogene SYT-SSX2. Oncogene. In press
    • Oncogene
    • Garcia, C.B.1    Shaffer, C.M.2    Alfaro, M.P.3
  • 7
    • 55449088278 scopus 로고    scopus 로고
    • First case report of a fetal synovial sarcoma confirmed by molecular detection of SYT-SSX fusion gene transcripts
    • Duband S., Morrison A. L., Pasquier D., Coindre J. M., Pasquier B., Péoc'h M., First case report of a fetal synovial sarcoma confirmed by molecular detection of SYT-SSX fusion gene transcripts American Journal of Perinatology 2008 25 8 517 520
    • (2008) American Journal of Perinatology , vol.25 , Issue.8 , pp. 517-520
    • Duband, S.1    Morrison, A.L.2    Pasquier, D.3    Coindre, J.M.4    Pasquier, B.5    Péoc'H, M.6
  • 8
    • 0035839882 scopus 로고    scopus 로고
    • Fusions of the SYT and SSX genes in synovial sarcoma
    • DOI 10.1038/sj.onc.1204601
    • Ladanyi M., Fusions of the SYT and SSX genes in synovial sarcoma Oncogene 2001 20 40 5755 5762 (Pubitemid 32928113)
    • (2001) Oncogene , vol.20 , Issue.40 REV. ISS. 4 , pp. 5755-5762
    • Ladanyi, M.1
  • 13
    • 0026082810 scopus 로고
    • Keratin subsets in spindle cell sarcomas. Keratins ae widespread but synovial sarcoma contains a distinctive keratin polypeptide pattern and desmoplakins
    • Miettinen M., Keratin subsets in spindle cell sarcomas. Keratins ae widespread but synovial sarcoma contains a distinctive keratin polypeptide pattern and desmoplakins American Journal of Pathology 1991 138 2 505 513
    • (1991) American Journal of Pathology , vol.138 , Issue.2 , pp. 505-513
    • Miettinen, M.1
  • 14
    • 0036827651 scopus 로고    scopus 로고
    • Monophasic fibrous and poorly differentiated synovial sarcoma: Immunohistochemical reassessment of 60 t(X;18)(SYT-SSX)-positive cases
    • DOI 10.1097/00000478-200211000-00005
    • Pelmus M., Guillou L., Hostein I., Sierankowski G., Lussan C., Coindre J. M., Monophasic fibrous and poorly differentiated synovial sarcoma: immunohistochemical reassessment of 60 t(X;18)(SYT-SSX)-positive cases American Journal of Surgical Pathology 2002 26 11 1434 1440 (Pubitemid 35239419)
    • (2002) American Journal of Surgical Pathology , vol.26 , Issue.11 , pp. 1434-1440
    • Pelmus, M.1    Guillou, L.2    Hostein, I.3    Sierankowski, G.4    Lussan, C.5    Coindre, J.-M.6
  • 15
    • 33646146940 scopus 로고    scopus 로고
    • Cluster analysis of immunohistochemical profiles in synovial sarcoma, malignant peripheral nerve sheath tumor, and Ewing sarcoma
    • Olsen S. H., Thomas D. G., Lucas D. R., Cluster analysis of immunohistochemical profiles in synovial sarcoma, malignant peripheral nerve sheath tumor, and Ewing sarcoma Modern Pathology 2006 19 5 659 668
    • (2006) Modern Pathology , vol.19 , Issue.5 , pp. 659-668
    • Olsen, S.H.1    Thomas, D.G.2    Lucas, D.R.3
  • 19
    • 0022871638 scopus 로고
    • Translocations involving the X chromosome in solid tumors: Presentation of two sarcomas with t[X;18][q13;p11]
    • DOI 10.1016/0165-4608(86)90152-4
    • Limon J., Dal Cin P., Sandberg A. A., Translocations involving the X chromosome in solid tumors: presentation of two sarcomas with t[X;18][q13;p11] Cancer Genetics and Cytogenetics 1986 23 1 87 91 (Pubitemid 16051843)
    • (1986) Cancer Genetics and Cytogenetics , vol.23 , Issue.1 , pp. 87-91
    • Limon, J.1    Dal Cin, P.2    Sandberg, A.A.3
  • 23
    • 0030777332 scopus 로고    scopus 로고
    • The SYT protein involved in the t(X;18) synovial sarcoma translocation is a transcriptional activator localised in nuclear bodies
    • DOI 10.1093/hmg/6.9.1559
    • Brett D., Whitehouse S., Antonson P., Shipley J., Cooper C., Goodwin G., The SYT protein involved in the t(X;18) synovial sarcoma translocation is a transcriptional activator localised in nuclear bodies Human Molecular Genetics 1997 6 9 1559 1564 (Pubitemid 27397034)
    • (1997) Human Molecular Genetics , vol.6 , Issue.9 , pp. 1559-1564
    • Brett, D.1    Whitehouse, S.2    Antonson, P.3    Shipley, J.4    Cooper, C.5    Goodwin, G.6
  • 25
    • 30044451566 scopus 로고    scopus 로고
    • The proto-oncoprotein SYT interacts with SYT-interacting protein/co-activator activator (SIP/CoAA), a human nuclear receptor co-activator with similarity to EWS and TLS/FUS family of proteins
    • DOI 10.1074/jbc.M502963200
    • Perani M., Antonson P., Hamoudi R., Ingram C. J. E., Cooper C. S., Garrett M. D., Goodwin G. M., The proto-oncoprotein SYT interacts with SYT-interacting protein/co-activator activator (SIP/CoAA), a human nuclear receptor co-activator with similarity to EWS and TLS/FUS family of proteins Journal of Biological Chemistry 2005 280 52 42863 42876 (Pubitemid 43049249)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.52 , pp. 42863-42876
    • Perani, M.1    Antonson, P.2    Hamoudi, R.3    Ingram, C.J.E.4    Cooper, C.S.5    Garrett, M.D.6    Goodwin, G.M.7
  • 26
    • 23844469208 scopus 로고    scopus 로고
    • Synovial sarcoma translocation (SYT) encodes a nuclear receptor coactivator
    • DOI 10.1210/en.2004-1513
    • Iwasaki T., Koibuchi N., Chin W. W., Synovial sarcoma translocation (SYT) encodes a nuclear receptor coactivator Endocrinology 2005 146 9 3892 3899 (Pubitemid 41175759)
    • (2005) Endocrinology , vol.146 , Issue.9 , pp. 3892-3899
    • Iwasaki, T.1    Koibuchi, N.2    Chin, W.W.3
  • 27
    • 0034664804 scopus 로고    scopus 로고
    • P300 Interacts with the nuclear proto-oncoprotein SYT as part of the active control of cell adhesion
    • Eid J. E., Kung A. L., Scully R., Livingston D. M., p300 Interacts with the nuclear proto-oncoprotein SYT as part of the active control of cell adhesion Cell 2000 102 6 839 848
    • (2000) Cell , vol.102 , Issue.6 , pp. 839-848
    • Eid, J.E.1    Kung, A.L.2    Scully, R.3    Livingston, D.M.4
  • 30
    • 0033035247 scopus 로고    scopus 로고
    • Functional domains of the SYT and SYT-SSX synovial sarcoma translocation proteins and co-localization with the SNF protein BRM in the nucleus
    • Thaete C., Brett D., Monaghan P., Whitehouse S., Rennie G., Rayner E., Cooper C. S., Goodwin G., Functional domains of the SYT and SYT-SSX synovial sarcoma translocation proteins and co-localization with the SNF protein BRM in the nucleus Human Molecular Genetics 1999 8 4 585 591 (Pubitemid 29139971)
    • (1999) Human Molecular Genetics , vol.8 , Issue.4 , pp. 585-591
    • Thaete, C.1    Brett, D.2    Monaghan, P.3    Whitehouse, S.4    Rennie, G.5    Rayner, E.6    Cooper, C.S.7    Goodwin, G.8
  • 31
    • 0345256334 scopus 로고    scopus 로고
    • Conserved SNH domain of the proto-oncoprotein SYT interacts with components of the human chromatin remodelling complexes, while the QPGY repeat domain forms homo-oligomers
    • DOI 10.1038/sj.onc.1207031
    • Perani M., Ingram C. J. E., Cooper C. S., Garrett M. D., Goodwin G. H., Conserved SNH domain of the proto-oncoprotein SYT interacts with components of the human chromatin remodelling complexes, while the QPGY repeat domain forms homo-oligomers Oncogene 2003 22 50 8156 8167 (Pubitemid 37487306)
    • (2003) Oncogene , vol.22 , Issue.50 , pp. 8156-8167
    • Perani, M.1    Ingram, C.J.E.2    Cooper, C.S.3    Garrett, M.D.4    Goodwin, G.H.5
  • 34
    • 8344287010 scopus 로고    scopus 로고
    • SYT, a partner of SYT-SSX oncoprotein in synovial sarcomas, interacts with mSin3A, a component of histone deacetylase complex
    • DOI 10.1038/labinvest.3700174
    • Ito T., Ouchida M., Ito S., Jitsumori Y., Morimoto Y., Ozaki T., Kawai A., Inoue H., Shimizu K., SYT, a partner of SYT-SSX oncoprotein in synovial sarcomas, interacts with mSin3A, a component of histone deacetylase complex Laboratory Investigation 2004 84 11 1484 1490 (Pubitemid 39482165)
    • (2004) Laboratory Investigation , vol.84 , Issue.11 , pp. 1484-1490
    • Ito, T.1    Ouchida, M.2    Ito, S.3    Jitsumori, Y.4    Morimoto, Y.5    Ozaki, T.6    Kawai, A.7    Inoue, H.8    Shimizu, K.9
  • 37
    • 55149113946 scopus 로고    scopus 로고
    • The proto-oncoprotein SYT (SS18) controls ATP release and regulates cyst formation by polarized MDCK cells
    • Chittezhath M., Frump A. L., Jourquin J., Lobdell N., Eid J. E., The proto-oncoprotein SYT (SS18) controls ATP release and regulates cyst formation by polarized MDCK cells Experimental Cell Research 2008 314 19 3551 3562
    • (2008) Experimental Cell Research , vol.314 , Issue.19 , pp. 3551-3562
    • Chittezhath, M.1    Frump, A.L.2    Jourquin, J.3    Lobdell, N.4    Eid, J.E.5
  • 41
    • 27444433159 scopus 로고    scopus 로고
    • SSX cancer testis antigens are expressed in most multiple myeloma patients: Co-expression of SSX1, 2, 4, and 5 correlates with adverse prognosis and high frequencies of SSX-positive PCs
    • Taylor B. J., Reiman T., Pittman J. A., Keats J. J., De Bruijn D. R. H., Mant M. J., Belch A. R., Pilarski L. M., SSX cancer testis antigens are expressed in most multiple myeloma patients: co-expression of SSX1, 2, 4, and 5 correlates with adverse prognosis and high frequencies of SSX-positive PCs Journal of Immunotherapy 2005 28 6 564 575 (Pubitemid 41533090)
    • (2005) Journal of Immunotherapy , vol.28 , Issue.6 , pp. 564-575
    • Taylor, B.J.1    Reiman, T.2    Pittman, J.A.3    Keats, J.J.4    De Bruijn, D.R.H.5    Mant, M.J.6    Belch, A.R.7    Pilarski, L.M.8
  • 47
    • 13944261158 scopus 로고    scopus 로고
    • Expression of cancer/testis (CT) antigens in Chinese hepatocellular carcinoma and its correlation with clinical parameters
    • DOI 10.1016/j.canlet.2004.07.028
    • Peng J. R., Chen H. S., Mou D. C., Cao J., Cong X., Qin L. L., Wei L., Leng X. S., Wang Y., Chen W. F., Expression of cancer/testis (CT) antigens in Chinese hepatocellular carcinoma and its correlation with clinical parameters Cancer Letters 2005 219 2 223 232 (Pubitemid 40269487)
    • (2005) Cancer Letters , vol.219 , Issue.2 , pp. 223-232
    • Peng, J.-R.1    Chen, H.-S.2    Mou, D.-C.3    Cao, J.4    Cong, X.5    Qin, L.-L.6    Wei, L.7    Leng, X.-S.8    Wang, Y.9    Chen, W.-F.10
  • 48
    • 33745654076 scopus 로고    scopus 로고
    • Expression of cancer-testis antigen (CTA) in tumor tissues and peripheral blood of Chinese patients with hepatocellular carcinoma
    • DOI 10.1016/j.lfs.2006.02.024, PII S0024320506001779
    • Wu L. Q., Lu Y., Wang X. F., Lv Z. H., Zhang B., Yang J. Y., Expression of cancer-testis antigen (CTA) in tumor tissues and peripheral blood of Chinese patients with hepatocellular carcinoma Life Sciences 2006 79 8 744 748 (Pubitemid 43975124)
    • (2006) Life Sciences , vol.79 , Issue.8 , pp. 744-748
    • Wu, L.-Q.1    Lu, Y.2    Wang, X.-F.3    Lv, Z.-H.4    Zhang, B.5    Yang, J.-Y.6
  • 50
    • 36849022167 scopus 로고    scopus 로고
    • Inducible expression of a prostate cancer-testis antigen, SSX-2, following treatment with a DNA methylation inhibitor
    • DOI 10.1002/pros.20665
    • Dubovsky J. A., McNeel D. G., Inducible expression of a prostate cancer-testis antigen, SSX-2, following treatment with a DNA methylation inhibitor Prostate 2007 67 16 1781 1790 (Pubitemid 350228730)
    • (2007) Prostate , vol.67 , Issue.16 , pp. 1781-1790
    • Dubovsky, J.A.1    McNeel, D.G.2
  • 51
    • 77956625908 scopus 로고    scopus 로고
    • Diagnostic value of cancer-testis antigen mRNA in peripheral blood from hepatocellular carcinoma patients
    • Zhao L., Mou D. C., Peng J. R., Huang L., Wu Z. A., Leng X. S., Diagnostic value of cancer-testis antigen mRNA in peripheral blood from hepatocellular carcinoma patients World Journal of Gastroenterology 2010 16 32 4072 4078
    • (2010) World Journal of Gastroenterology , vol.16 , Issue.32 , pp. 4072-4078
    • Zhao, L.1    Mou, D.C.2    Peng, J.R.3    Huang, L.4    Wu, Z.A.5    Leng, X.S.6
  • 59
    • 0032532777 scopus 로고    scopus 로고
    • A KRAB-related domain and a novel transcription repression domain in proteins encoded by SSX genes that are disrupted in human sarcomas
    • Lim F. L., Soulez M., Koczan D., Thiesen H. J., Knight J. C., A KRAB-related domain and a novel transcription repression domain in proteins encoded by SSX genes that are disrupted in human sarcomas Oncogene 1998 17 15 2013 2018 (Pubitemid 28488471)
    • (1998) Oncogene , vol.17 , Issue.15 , pp. 2013-2018
    • Lim, F.L.1    Soulez, M.2    Koczan, D.3    Thiesen, H.-J.4    Knight, J.C.5
  • 61
    • 0033614357 scopus 로고    scopus 로고
    • SSX and the synovial-sarcoma-specific chimaeric protein SYT-SSX co-localize with the human Polycomb group complex
    • DOI 10.1038/sj.onc.1202613
    • Soulez M., Saurin A. J., Freemont P. S., Knight J. C., SSX and the synovial-sarcoma-specific chimaeric protein SYT-SSX co-localize with the human Polycomb group complex Oncogene 1999 18 17 2739 2746 (Pubitemid 29237662)
    • (1999) Oncogene , vol.18 , Issue.17 , pp. 2739-2746
    • Soulez, M.1    Saurin, A.J.2    Freemont, P.S.3    Knight, J.C.4
  • 62
    • 16844362032 scopus 로고    scopus 로고
    • Cancer/testis antigen expression in human mesenchymal stem cells: Down-regulation of SSX impairs cell migration and matrix metalloproteinase 2 expression
    • DOI 10.1158/0008-5472.CAN-04-1882
    • Cronwright G., Le Blanc K., Gtherstrm C., Darcy P., Ehnman M., Brodin B., Cancer/testis antigen expression in human mesenchymal stem cells: down-regulation of SSX impairs cell migration and matrix metalloproteinase 2 expression Cancer Research 2005 65 6 2207 2215 (Pubitemid 40490129)
    • (2005) Cancer Research , vol.65 , Issue.6 , pp. 2207-2215
    • Cronwright, G.1    Le Blanc, K.2    Gotherstrom, C.3    Darcy, P.4    Ehnman, M.5    Brodin, B.6
  • 64
    • 0029066330 scopus 로고
    • Fusion of SYT to two genes, SSX1 and SSX2, encoding proteins with homology to the Kruppel-associated box in human synovial sarcoma
    • Crew A. J., Clark J., Fisher C., Gill S., Grimer R., Chand A., Shipley J., Gusterson B. A., Cooper C. S., Fusion of SYT to two genes, SSX1 and SSX2, encoding proteins with homology to the Kruppel-associated box in human synovial sarcoma EMBO Journal 1995 14 10 2333 2340
    • (1995) EMBO Journal , vol.14 , Issue.10 , pp. 2333-2340
    • Crew, A.J.1    Clark, J.2    Fisher, C.3    Gill, S.4    Grimer, R.5    Chand, A.6    Shipley, J.7    Gusterson, B.A.8    Cooper, C.S.9
  • 65
    • 0032518634 scopus 로고    scopus 로고
    • SYT-SSX gene fusion as a determinant of morphology and prognosis in synovial sarcoma
    • DOI 10.1056/NEJM199801153380303
    • Kawai A., Woodruff J., Healey J. H., Brennan M. F., Antonescu C. R., Ladanyi M., SYT-SSX gene fusion as a determinant of morphology and prognosis in synovial sarcoma New England Journal of Medicine 1998 338 3 153 160 (Pubitemid 28041862)
    • (1998) New England Journal of Medicine , vol.338 , Issue.3 , pp. 153-160
    • Kawai, A.1    Woodruff, J.2    Healey, J.H.3    Brennan, M.F.4    Antonescu, C.R.5    Ladanyi, M.6
  • 68
    • 0035795649 scopus 로고    scopus 로고
    • Cloning and characterization of spliced fusion transcript variants of synovial sarcoma: SYT/SSX4, SYT/SSX4v, and SYT/SSX2v. Possible regulatory role of the fusion gene product in wild type SYT expression
    • DOI 10.1016/S0378-1119(01)00412-7, PII S0378111901004127
    • Brodin B., Haslam K., Yang K., Bartolazzi A., Xie Y., Starborg M., Lundeberg J., Larsson O., Cloning and characterization of spliced fusion transcript variants of synovial sarcoma: SYT/SSX4, SYT/SSX4v, and SYT/SSX2v. Possible regulatory role of the fusion gene product in wild type SYT expression Gene 2001 268 1-2 173 182 (Pubitemid 32463801)
    • (2001) Gene , vol.268 , Issue.1-2 , pp. 173-182
    • Brodin, B.1    Haslam, K.2    Yang, K.3    Bartolazzi, A.4    Xie, Y.5    Starborg, M.6    Lundeberg, J.7    Larsson, O.8
  • 70
    • 34548719285 scopus 로고    scopus 로고
    • Molecular characterization of a novel variant of a SYT-SSX1 fusion transcript in synovial sarcoma [6]
    • DOI 10.1111/j.1365-2559.2007.02812.x
    • Amary M. F. C., Diss T. C., Flanagan A. M., Molecular characterization of a novel variant of a SYT-SSX1 fusion transcript in synovial sarcoma [6] Histopathology 2007 51 4 559 561 (Pubitemid 47437837)
    • (2007) Histopathology , vol.51 , Issue.4 , pp. 559-561
    • Amary, M.F.C.1    Diss, T.C.2    Flanagan, A.M.3
  • 71
    • 0033168038 scopus 로고    scopus 로고
    • The SYT-SSX1 variant of synovial sarcoma is associated with a high rate of tumor cell proliferation and poor clinical outcome
    • Nilsson G., Skytting B., Xie Y., Brodin B., Perfekt R., Mandahl N., Lundeberg J., Uhlén M., Larsson O., The SYT-SSX1 variant of synovial sarcoma is associated with a high rate of tumor cell proliferation and poor clinical outcome Cancer Research 1999 59 13 3180 3184 (Pubitemid 29316020)
    • (1999) Cancer Research , vol.59 , Issue.13 , pp. 3180-3184
    • Nilsson, G.1    Skytting, B.2    Xie, Y.3    Brodin, B.4    Perfekt, R.5    Mandahl, N.6    Lundeberg, J.7    Uhlen, M.8    Larsson, O.9
  • 72
    • 0034008724 scopus 로고    scopus 로고
    • Strong association of SYT-SSX fusion type and morphologic epithelial differentiation in synovial sarcoma
    • DOI 10.1097/00019606-200003000-00001
    • Antonescu C. R., Kawai A., Leung D. H., Lonardo F., Woodruff J. M., Healey J. H., Ladanyi M., Strong association of SYT-SSX fusion type and morphologic epithelial differentiation in synovial sarcoma Diagnostic Molecular Pathology 2000 9 1 1 8 (Pubitemid 30131955)
    • (2000) Diagnostic Molecular Pathology , vol.9 , Issue.1 , pp. 1-8
    • Antonescu, C.R.1    Kawai, A.2    Leung, D.H.3    Lonardo, F.4    Woodruff, J.M.5    Healey, J.H.6    Ladanyi, M.7
  • 73
    • 33746906998 scopus 로고    scopus 로고
    • SYT-SSX1 and SYT-SSX2 interfere with repression of E-cadherin by snail and slug: A potential mechanism for aberrant mesenchymal to epithelial transition in human synovial sarcoma
    • DOI 10.1158/0008-5472.CAN-05-3697
    • Saito T., Nagai M., Ladanyi M., SYT-SSX1 and SYT-SSX2 interfere with repression of E-cadherin by snail and slug: a potential mechanism for aberrant mesenchymal to epithelial transition in human synovial sarcoma Cancer Research 2006 66 14 6919 6927 (Pubitemid 44197666)
    • (2006) Cancer Research , vol.66 , Issue.14 , pp. 6919-6927
    • Saito, T.1    Nagai, M.2    Ladanyi, M.3
  • 77
    • 0034078438 scopus 로고    scopus 로고
    • Association of SYT-SSX fusion types with proliferative activity and prognosis in synovial sarcoma
    • Inagaki H., Nagasaka T., Otsuka T., Sugiura E., Nakashima N., Eimoto T., Association of SYT-SSX fusion types with proliferative activity and prognosis in synovial sarcoma Modern Pathology 2000 13 5 482 488 (Pubitemid 30332098)
    • (2000) Modern Pathology , vol.13 , Issue.5 , pp. 482-488
    • Inagaki, H.1    Nagasaka, T.2    Otsuka, T.3    Sugiura, E.4    Nakashima, N.5    Eimoto, T.6
  • 78
    • 67649887764 scopus 로고    scopus 로고
    • Prognostic implication of SYT-SSX fusion type and clinicopathological parameters for tumor-related death, recurrence, and metastasis in synovial sarcoma
    • Sun Y., Sun B., Wang J., Cai W., Zhao X., Zhang S., Hao X., Prognostic implication of SYT-SSX fusion type and clinicopathological parameters for tumor-related death, recurrence, and metastasis in synovial sarcoma Cancer Science 2009 100 6 1018 1025
    • (2009) Cancer Science , vol.100 , Issue.6 , pp. 1018-1025
    • Sun, Y.1    Sun, B.2    Wang, J.3    Cai, W.4    Zhao, X.5    Zhang, S.6    Hao, X.7
  • 79
    • 77949496548 scopus 로고    scopus 로고
    • The influence of SYT-SSX fusion gene, E-cadherin and -catenin on the metastasis of synovial sarcoma
    • Wei X., Sun Y., Zhao X., Cai W., Xia W., Lou D., Ban X., Sun B., The influence of SYT-SSX fusion gene, E-cadherin and -catenin on the metastasis of synovial sarcoma Chinese Journal of Clinical Oncology 2010 37 4 205 208
    • (2010) Chinese Journal of Clinical Oncology , vol.37 , Issue.4 , pp. 205-208
    • Wei, X.1    Sun, Y.2    Zhao, X.3    Cai, W.4    Xia, W.5    Lou, D.6    Ban, X.7    Sun, B.8
  • 80
    • 20644441344 scopus 로고    scopus 로고
    • Correlates of SYT-SSX fusion type in synovial sarcoma: Getting more complex but also more interesting?
    • Ladanyi M., Correlates of SYT-SSX fusion type in synovial sarcoma: getting more complex but also more interesting? Journal of Clinical Oncology 2005 23 15 3638 3639
    • (2005) Journal of Clinical Oncology , vol.23 , Issue.15 , pp. 3638-3639
    • Ladanyi, M.1
  • 82
    • 18744385495 scopus 로고    scopus 로고
    • The SYT-SSX1 fusion type of synovial sarcoma is associated with increased expression of cyclin A and D1. A link between t(X;18)(p11.2; q11.2) and the cell cycle machinery
    • DOI 10.1038/sj.onc.1205700
    • Xie Y., Skytting B., Nilsson G., Grimer R. J., Mangham C. D., Fisher C., Shipley J., Bjerkehagen B., Myklebost O., Larsson O., The SYT-SSX1 fusion type of synovial sarcoma is associated with increased expression of cyclin A and D1. A link between t(X;18)(p11.2; q11.2) and the cell cycle machinery Oncogene 2002 21 37 5791 5796 (Pubitemid 35333013)
    • (2002) Oncogene , vol.21 , Issue.37 , pp. 5791-5796
    • Xie, Y.1    Skytting, B.2    Nilsson, G.3    Grimer, R.J.4    Mangham, C.D.5    Fisher, C.6    Shipley, J.7    Bjerkehagen, B.8    Myklebost, O.9    Larsson, O.10
  • 83
    • 56149108580 scopus 로고    scopus 로고
    • Downregulation of ss18-ssx1 expression by small interfering rna inhibits growth and induces apoptosis in human synovial sarcoma cell line HS-SY-II in vitro
    • Peng C., Guo W., Yang Y., Zhao H., Downregulation of ss18-ssx1 expression by small interfering rna inhibits growth and induces apoptosis in human synovial sarcoma cell line HS-SY-II in vitro European Journal of Cancer Prevention 2008 17 5 392 398
    • (2008) European Journal of Cancer Prevention , vol.17 , Issue.5 , pp. 392-398
    • Peng, C.1    Guo, W.2    Yang, Y.3    Zhao, H.4
  • 84
    • 0036645310 scopus 로고    scopus 로고
    • SYT-SSX is critical for cyclin D1 expression in synovial sarcoma cells: A gain of function of the t(X;18)(p11.2;q11.2) translocation
    • Xie Y., Skytting B., Nilsson G., Gasbarri A., Haslam K., Bartolazzi A., Brodin B., Mandahl N., Larsson O., SYT-SSX is critical for cyclin D1 expression in synovial sarcoma cells: a gain of function of the t(X;18)(p11.2;q11.2) translocation Cancer Research 2002 62 13 3861 3867 (Pubitemid 34728873)
    • (2002) Cancer Research , vol.62 , Issue.13 , pp. 3861-3867
    • Xie, Y.1    Skytting, B.2    Nilsson, G.3    Gasbarri, A.4    Haslam, K.5    Bartolazzi, A.6    Brodin, B.7    Mandahl, N.8    Larsson, O.9
  • 86
    • 33745543651 scopus 로고    scopus 로고
    • The synovial sarcoma translocation protein SYT-SSX2 recruits β-catenin to the nucleus and associates with it in an active complex
    • DOI 10.1038/sj.onc.1209413, PII 1209413
    • Pretto D., Barco R., Rivera J., Neel N., Gustavson M. D., Eid J. E., The synovial sarcoma translocation protein SYT-SSX2 recruits -catenin to the nucleus and associates with it in an active complex Oncogene 2006 25 26 3661 3669 (Pubitemid 43980487)
    • (2006) Oncogene , vol.25 , Issue.26 , pp. 3661-3669
    • Pretto, D.1    Barco, R.2    Rivera, J.3    Neel, N.4    Gustavson, M.D.5    Eid, J.E.6
  • 87
    • 0034232066 scopus 로고    scopus 로고
    • Curbing the nuclear activities of -catenin: Control over Wnt target gene expression
    • Hecht A., Kemler R., Curbing the nuclear activities of -catenin: control over Wnt target gene expression EMBO Reports 2000 1 1 24 28
    • (2000) EMBO Reports , vol.1 , Issue.1 , pp. 24-28
    • Hecht, A.1    Kemler, R.2
  • 88
    • 33745034581 scopus 로고    scopus 로고
    • β-catenin nuclear expression correlates with cyclin D1 expression in primary and metastatic synovial sarcoma: A tissue microarray study
    • Horvai A. E., Kramer M. J., O'Donnell R., -catenin nuclear expression correlates with cyclin D1 expression in primary and metastatic synovial sarcoma: a tissue microarray study Archives of Pathology and Laboratory Medicine 2006 130 6 792 798 (Pubitemid 43886997)
    • (2006) Archives of Pathology and Laboratory Medicine , vol.130 , Issue.6 , pp. 792-798
    • Horvai, A.E.1    Kramer, M.J.2    O'Donnell, R.3
  • 89
    • 67649698279 scopus 로고    scopus 로고
    • Molecular characterization of synovial sarcoma in children and adolescents: Evidence of akt activation
    • Bozzi F., Ferrari A., Negri T., Molecular characterization of synovial sarcoma in children and adolescents: evidence of akt activation Translational Oncology 2008 1 2 95 101
    • (2008) Translational Oncology , vol.1 , Issue.2 , pp. 95-101
    • Bozzi, F.1    Ferrari, A.2    Negri, T.3
  • 90
    • 0344873125 scopus 로고    scopus 로고
    • Gene expression profile by blocking the SYT-SSX fusion gene in synovial sarcoma cells. Identification of XRCC4 as a putative SYT-SSX target gene
    • DOI 10.1038/sj.onc.1207153
    • Xie Y., Trnkvist M., Aalto Y., Nilsson G., Girnita L., Nagy B., Knuutila S., Larsson O., Gene expression profile by blocking the SYT-SSX fusion gene in synovial sarcoma cells. Identification of XRCC4 as a putative SYT-SSX target gene Oncogene 2003 22 48 7628 7631 (Pubitemid 37464096)
    • (2003) Oncogene , vol.22 , Issue.48 , pp. 7628-7631
    • Xie, Y.1    Tornkvist, M.2    Aalto, Y.3    Nilsson, G.4    Girnita, L.5    Nagy, B.6    Knuutila, S.7    Larsson, O.8
  • 91
    • 40749103341 scopus 로고    scopus 로고
    • The oncoprotein SS18-SSX1 promotes p53 ubiquitination and degradation by enhancing HDM2 stability
    • DOI 10.1158/1541-7786.MCR-07-0176
    • D'Arcy P., Maruwge W., Ryan B. A., Brodin B., The oncoprotein SS18-SSX1 promotes p53 ubiquitination and degradation by enhancing HDM2 stability Molecular Cancer Research 2008 6 1 127 138 (Pubitemid 351378173)
    • (2008) Molecular Cancer Research , vol.6 , Issue.1 , pp. 127-138
    • D'Arcy, P.1    Maruwge, W.2    Ryan, B.A.3    Brodin, B.4
  • 92
    • 59349107039 scopus 로고    scopus 로고
    • Reactivation of p53 function in synovial sarcoma cells by inhibition of p53-HDM2 interaction
    • D'Arcy P., Ryan B. A., Brodin B., Reactivation of p53 function in synovial sarcoma cells by inhibition of p53-HDM2 interaction Cancer Letters 2009 275 2 285 292
    • (2009) Cancer Letters , vol.275 , Issue.2 , pp. 285-292
    • D'Arcy, P.1    Ryan, B.A.2    Brodin, B.3
  • 96
    • 77955177292 scopus 로고    scopus 로고
    • EGR1 reactivation by histone deacetylase inhibitors promotes synovial sarcoma cell death through the PTEN tumor suppressor
    • Su L., Cheng H., Sampaio A. V., Nielsen T. O., Underhill T. M., EGR1 reactivation by histone deacetylase inhibitors promotes synovial sarcoma cell death through the PTEN tumor suppressor Oncogene 2010 29 30 4352 4361
    • (2010) Oncogene , vol.29 , Issue.30 , pp. 4352-4361
    • Su, L.1    Cheng, H.2    Sampaio, A.V.3    Nielsen, T.O.4    Underhill, T.M.5
  • 97
    • 78649910285 scopus 로고    scopus 로고
    • MicroRNA miR-183 functions as an oncogene by targeting the transcription factor EGR1 and promoting tumor cell migration
    • Sarver A. L., Li H., Subramanian S., MicroRNA miR-183 functions as an oncogene by targeting the transcription factor EGR1 and promoting tumor cell migration Cancer Research 2010 70 23 9570 9580
    • (2010) Cancer Research , vol.70 , Issue.23 , pp. 9570-9580
    • Sarver, A.L.1    Li, H.2    Subramanian, S.3
  • 98
    • 70949102042 scopus 로고    scopus 로고
    • Epigenetic features of human mesenchymal stem cells determine their permissiveness for induction of relevant transcriptional changes by SYT-SSX1
    • Cironi L., Provero P., Riggi N., Janiszewska M., Suva D., Suva M. L., Kindler V., Stamenkovic I., Epigenetic features of human mesenchymal stem cells determine their permissiveness for induction of relevant transcriptional changes by SYT-SSX1 PLoS ONE 2009 4 11
    • (2009) PLoS ONE , vol.4 , Issue.11
    • Cironi, L.1    Provero, P.2    Riggi, N.3    Janiszewska, M.4    Suva, D.5    Suva, M.L.6    Kindler, V.7    Stamenkovic, I.8
  • 99
    • 33244494390 scopus 로고    scopus 로고
    • IGF2 is critical for tumorigenesis by synovial sarcoma oncoprotein SYT-SSX1
    • DOI 10.1038/sj.onc.1209143, PII 1209143
    • Sun Y., Gao D., Liu Y., Huang J., Lessnick S., Tanaka S., IGF2 is critical for tumorigenesis by synovial sarcoma oncoprotein SYT-SSX1 Oncogene 2006 25 7 1042 1052 (Pubitemid 43277012)
    • (2006) Oncogene , vol.25 , Issue.7 , pp. 1042-1052
    • Sun, Y.1    Gao, D.2    Liu, Y.3    Huang, J.4    Lessnick, S.5    Tanaka, S.6
  • 101
    • 0033179378 scopus 로고    scopus 로고
    • Expression of insulin-like growth factor-1 receptor in synovial sarcoma: Association with an aggressive phenotype
    • Xie Y., Skytting B., Nilsson G., Brodin B., Larsson O., Expression of insulin-like growth factor-1 receptor in synovial sarcoma: association with an aggressive phenotype Cancer Research 1999 59 15 3588 3591 (Pubitemid 29381857)
    • (1999) Cancer Research , vol.59 , Issue.15 , pp. 3588-3591
    • Xie, Y.1    Skytting, B.2    Nilsson, G.3    Brodin, B.4    Larsson, O.5
  • 102
    • 0034693756 scopus 로고    scopus 로고
    • The contradictions of the insulin-like growth factor 1 receptor
    • Baserga R., The contradictions of the insulin-like growth factor 1 receptor Oncogene 2000 19 49 5574 5581
    • (2000) Oncogene , vol.19 , Issue.49 , pp. 5574-5581
    • Baserga, R.1
  • 103
    • 0036840271 scopus 로고    scopus 로고
    • Expression profiling of synovial sarcoma by cDNA microarrays: Association of ERBB2, IGFBP2, and ELF3 with epithelial differentiation
    • Allander S. V., Illei P. B., Chen Y., Antonescu C. R., Bittner M., Ladanyi M., Meltzer P. S., Expression profiling of synovial sarcoma by cDNA microarrays: association of ERBB2, IGFBP2, and ELF3 with epithelial differentiation American Journal of Pathology 2002 161 5 1587 1595 (Pubitemid 35265519)
    • (2002) American Journal of Pathology , vol.161 , Issue.5 , pp. 1587-1595
    • Allander, S.V.1    Illei, P.B.2    Chen, Y.3    Antonescu, C.R.4    Bittner, M.5    Ladanyi, M.6    Meltzer, P.S.7
  • 106
    • 67650688576 scopus 로고    scopus 로고
    • Expression of insulin-like growth factor 2 in mesenchymal neoplasms
    • Steigen S. E., Schaeffer D. F., West R. B., Nielsen T. O., Expression of insulin-like growth factor 2 in mesenchymal neoplasms Modern Pathology 2009 22 7 914 921
    • (2009) Modern Pathology , vol.22 , Issue.7 , pp. 914-921
    • Steigen, S.E.1    Schaeffer, D.F.2    West, R.B.3    Nielsen, T.O.4
  • 107
    • 80051668580 scopus 로고    scopus 로고
    • The effect of SYT-SSX and extracellular signal-regulated kinase (ERK) on cell proliferation in Synovial sarcoma
    • Cai W., Sun Y., Wang W., Han C., Ouchida M., Xia W., Zhao X., Sun B., The effect of SYT-SSX and extracellular signal-regulated kinase (ERK) on cell proliferation in Synovial sarcoma Pathology and Oncology Research 2011 17 2 357 367
    • (2011) Pathology and Oncology Research , vol.17 , Issue.2 , pp. 357-367
    • Cai, W.1    Sun, Y.2    Wang, W.3    Han, C.4    Ouchida, M.5    Xia, W.6    Zhao, X.7    Sun, B.8
  • 109
    • 33748951908 scopus 로고    scopus 로고
    • Essential role for activation of the polycomb group (PcG) protein chromatin silencing pathway in metastatic prostate cancer
    • Berezovska O. P., Glinskii A. B., Yang Z., Li X. M., Hoffman R. M., Glinsky G. V., Essential role for activation of the polycomb group (PcG) protein chromatin silencing pathway in metastatic prostate cancer Cell Cycle 2006 5 16 1886 1901 (Pubitemid 44435335)
    • (2006) Cell Cycle , vol.5 , Issue.16 , pp. 1886-1901
    • Berezovska, O.P.1    Glinskii, A.B.2    Yang, Z.3    Li, X.-M.4    Hoffman, R.M.5    Glinsky, G.V.6
  • 110
    • 34249692139 scopus 로고    scopus 로고
    • The polycomb group BMI1 gene is a molecular marker for predicting prognosis of chronic myeloid leukemia
    • DOI 10.1182/blood-2006-12-065599
    • Mohty M., Yong A. S. M., Szydlo R. M., Apperley J. F., Melo J. V., The polycomb group BMI1 gene is a molecular marker for predicting prognosis of chronic myeloid leukemia Blood 2007 110 1 380 383 (Pubitemid 47026858)
    • (2007) Blood , vol.110 , Issue.1 , pp. 380-383
    • Mohty, M.1    Yong, A.S.M.2    Szydlo, R.M.3    Apperley, J.F.4    Melo, J.V.5
  • 112
    • 34347233480 scopus 로고    scopus 로고
    • Mel-18 acts as a tumor suppressor by repressing Bmi-1 expression and down-regulating Akt activity in breast cancer cells
    • DOI 10.1158/0008-5472.CAN-06-4368
    • Guo W. J., Zeng M. S., Yadav A., Song L. B., Guo B. H., Band V., Dimri G. P., Mel-18 acts as a tumor suppressor by repressing Bmi-1 expression and down-regulating Akt activity in breast cancer cells Cancer Research 2007 67 11 5083 5089 (Pubitemid 46997242)
    • (2007) Cancer Research , vol.67 , Issue.11 , pp. 5083-5089
    • Guo, W.-J.1    Zeng, M.-S.2    Yadav, A.3    Song, L.-B.4    Guo, B.-H.5    Band, V.6    Dimri, G.P.7
  • 113
    • 0034630343 scopus 로고    scopus 로고
    • Delineation of the protein domains responsible for SYT, SSX, and SYT-SSX nuclear localization
    • DOI 10.1006/excr.2000.4813
    • dos Santos N. R., de Bruijn D. R. H., Kater-Baats E., Otte A. P., Van Kessel A. G., Delineation of the protein domains responsible for SYT, SSX, and SYT-SSX nuclear localization Experimental Cell Research 2000 256 1 192 202 (Pubitemid 30211181)
    • (2000) Experimental Cell Research , vol.256 , Issue.1 , pp. 192-202
    • Dos Santos, N.R.1    De Bruijn, D.R.H.2    Kater-Baats, E.3    Otte, A.P.4    Van Kessel, A.G.5
  • 114
    • 64249153080 scopus 로고    scopus 로고
    • The synovial sarcoma-associated SYT-SSX2 oncogene antagonizes the polycomb complex protein Bmi1
    • Barco R., Garcia C. B., Eid J. E., The synovial sarcoma-associated SYT-SSX2 oncogene antagonizes the polycomb complex protein Bmi1 PLoS ONE 2009 4 4
    • (2009) PLoS ONE , vol.4 , Issue.4
    • Barco, R.1    Garcia, C.B.2    Eid, J.E.3
  • 115
    • 19444376494 scopus 로고    scopus 로고
    • Significant growth suppression of synovial sarcomas by the histone deacetylase inhibitor FK228 in vitro and in vivo
    • DOI 10.1016/j.canlet.2004.10.030, PII S0304383504008122
    • Ito T., Ouchida M., Morimoto Y., Yoshida A., Jitsumori Y., Ozaki T., Sonobe H., Inoue H., Shimizu K., Significant growth suppression of synovial sarcomas by the histone deacetylase inhibitor FK228 in vitro and in vivo Cancer Letters 2005 224 2 311 319 (Pubitemid 40725851)
    • (2005) Cancer Letters , vol.224 , Issue.2 , pp. 311-319
    • Ito, T.1    Ouchida, M.2    Morimoto, Y.3    Yoshida, A.4    Jitsumori, Y.5    Ozaki, T.6    Sonobe, H.7    Inoue, H.8    Shimizu, K.9
  • 117
    • 34948816089 scopus 로고    scopus 로고
    • The synovial sarcoma SYT-SSX2 oncogene remodels the cytoskeleton through activation of the ephrin pathway
    • DOI 10.1091/mbc.E07-05-0496
    • Barco R., Hunt L. B., Frump A. L., Garcia C. B., Benesh A., Caldwell R. L., Eid J. E., The synovial sarcoma SYT-SSX2 oncogene remodels the cytoskeleton through activation of the ephrin pathway Molecular Biology of the Cell 2007 18 10 4003 4012 (Pubitemid 47519491)
    • (2007) Molecular Biology of the Cell , vol.18 , Issue.10 , pp. 4003-4012
    • Barco, R.1    Hunt, L.B.2    Frump, A.L.3    Garcia, C.B.4    Benesh, A.5    Caldwell, R.L.6    Eid, J.E.7
  • 118
    • 70349696530 scopus 로고    scopus 로고
    • EGFR-dependent and independent activation of Akt/mTOR cascade in bone and soft tissue tumors
    • Dobashi Y., Suzuki S., Sato E., Hamada Y., Yanagawa T., Ooi A., EGFR-dependent and independent activation of Akt/mTOR cascade in bone and soft tissue tumors Modern Pathology 2009 22 10 1328 1340
    • (2009) Modern Pathology , vol.22 , Issue.10 , pp. 1328-1340
    • Dobashi, Y.1    Suzuki, S.2    Sato, E.3    Hamada, Y.4    Yanagawa, T.5    Ooi, A.6
  • 120
    • 0026569415 scopus 로고
    • Platelet-derived growth factor receptor ( -subunit) immunoreactivity in soft tissue tumors
    • Palman C., Bowen-Pope D. F., Brooks J. J., Platelet-derived growth factor receptor ( -subunit) immunoreactivity in soft tissue tumors Laboratory Investigation 1992 66 1 108 115
    • (1992) Laboratory Investigation , vol.66 , Issue.1 , pp. 108-115
    • Palman, C.1    Bowen-Pope, D.F.2    Brooks, J.J.3
  • 121
    • 0034254249 scopus 로고    scopus 로고
    • Inhibition of c-kit receptor tyrosine kinase activity by STI 571 a selective tyrosine kinase inhibitor
    • Heinrich M. C., Griffith D. J., Druker B. J., Wait C. L., Ott K. A., Zigler A. J., Inhibition of c-kit receptor tyrosine kinase activity by STI 571 a selective tyrosine kinase inhibitor Blood 2000 96 3 925 932 (Pubitemid 30618049)
    • (2000) Blood , vol.96 , Issue.3 , pp. 925-932
    • Heinrich, M.C.1    Griffith, D.J.2    Druker, B.J.3    Wait, C.L.4    Ott, K.A.5    Zigler, A.J.6
  • 124
    • 1042301962 scopus 로고    scopus 로고
    • Expression of Ligand-Activated KIT and Platelet-Derived Growth Factor Receptor β Tyrosine Kinase Receptors in Synovial Sarcoma
    • DOI 10.1158/1078-0432.CCR-03-0059
    • Tamborini E., Bonadiman L., Greco A., Gronchi A., Riva C., Bertulli R., Casali P. G., Pierotti M. A., Pilotti S., Expression of Ligand-Activated KIT and Platelet-Derived Growth Factor Receptor Tyrosine Kinase Receptors in Synovial Sarcoma Clinical Cancer Research 2004 10 3 938 943 (Pubitemid 38198893)
    • (2004) Clinical Cancer Research , vol.10 , Issue.3 , pp. 938-943
    • Tamborini, E.1    Bonadiman, L.2    Greco, A.3    Gronchi, A.4    Riva, C.5    Bertulli, R.6    Casali, P.G.7    Pierotti, M.A.8    Pilotti, S.9
  • 126
    • 13444291031 scopus 로고    scopus 로고
    • Expression of receptor tyrosine kinases epidermal growth factor receptor and HER-2/ neu in synovial sarcoma
    • DOI 10.1002/cncr.20847
    • Thomas D. G., Giordano T. J., Sanders D., Biermann S., Sondak V. K., Trent J. C., Yu D., Pollock R. E., Baker L., Expression of receptor tyrosine kinases epidermal growth factor receptor and HER-2/ neu in synovial sarcoma Cancer 2005 103 4 830 838 (Pubitemid 40216413)
    • (2005) Cancer , vol.103 , Issue.4 , pp. 830-838
    • Thomas, D.G.1    Giordano, T.J.2    Sanders, D.3    Biermann, S.4    Sondak, V.K.5    Trent, J.C.6    Yu, D.7    Pollock, R.E.8    Baker, L.9
  • 127
  • 128
    • 67651094040 scopus 로고    scopus 로고
    • Molecular and immunohistochemical analyses of BCL2, KI-67, andcyclin D1 expression in synovial sarcoma
    • Krskov L., Kalinov M., Bzov H., Mrhalov M., Sumerauer D., Kodet R., Molecular and immunohistochemical analyses of BCL2, KI-67, andcyclin D1 expression in synovial sarcoma Cancer Genetics and Cytogenetics 2009 193 1 1 8
    • (2009) Cancer Genetics and Cytogenetics , vol.193 , Issue.1 , pp. 1-8
    • Krskov, L.1    Kalinov, M.2    Bzov, H.3    Mrhalov, M.4    Sumerauer, D.5    Kodet, R.6
  • 131
    • 17444379015 scopus 로고    scopus 로고
    • Deregulated expression of polycomb-group oncogenes in human malignant lymphomas and epithelial tumors
    • Raaphorst F. M., Deregulated expression of polycomb-group oncogenes in human malignant lymphomas and epithelial tumors Human Molecular Genetics 2005 14 1 R93 R100
    • (2005) Human Molecular Genetics , vol.14 , Issue.1
    • Raaphorst, F.M.1
  • 132
    • 41849112039 scopus 로고    scopus 로고
    • Role of Polycomb-group genes in sustaining activities of normal and malignant stem cells
    • Takihara Y., Role of Polycomb-group genes in sustaining activities of normal and malignant stem cells International Journal of Hematology 2008 87 1 25 34
    • (2008) International Journal of Hematology , vol.87 , Issue.1 , pp. 25-34
    • Takihara, Y.1
  • 133
    • 77950889840 scopus 로고    scopus 로고
    • Dietary omega-3 polyunsaturated fatty acids suppress expression of EZH2 in breast cancer cells
    • Dimri M., Bommi P. V., Sahasrabuddhe A. A., Khandekar J. D., Dimri G. P., Dietary omega-3 polyunsaturated fatty acids suppress expression of EZH2 in breast cancer cells Carcinogenesis 2010 31 3 489 495
    • (2010) Carcinogenesis , vol.31 , Issue.3 , pp. 489-495
    • Dimri, M.1    Bommi, P.V.2    Sahasrabuddhe, A.A.3    Khandekar, J.D.4    Dimri, G.P.5
  • 135
    • 43549083034 scopus 로고    scopus 로고
    • A phase II study of gefitinib for patients with advanced HER-1 expressing synovial sarcoma refractory to doxorubicin-containing regimens
    • DOI 10.1634/theoncologist.2008-0065
    • Ray-Coquard I., Le Cesne A., Whelan J. S., Schoffski P., Bui B. N., Verweij J., Marreaud S., Van Glabbeke M., Hogendoorn P., Blay J. Y., A phase II study of gefitinib for patients with advanced HER-1 expressing synovial sarcoma refractory to doxorubicin-containing regimens Oncologist 2008 13 4 467 473 (Pubitemid 351679928)
    • (2008) Oncologist , vol.13 , Issue.4 , pp. 467-473
    • Ray-Coquard, I.1    Le Cesne, A.2    Whelan, J.S.3    Schoffski, P.4    Bui, B.N.5    Verweij, J.6    Marreaud, S.7    Van Glabbeke, M.8    Hogendoorn, P.9    Blay, J.-Y.10
  • 138
    • 0032533875 scopus 로고    scopus 로고
    • cAMP-response-element-binding-protein-binding protein (CBP) and p300 are transcriptional co-activators of early growth response factor-1 (Egr-1)
    • Silverman E. S., Du J., Williams A. J., Wadgaonkar R., Drazen J. M., Collins T., cAMP-response-element-binding-protein-binding protein (CBP) and p300 are transcriptional co-activators of early growth response factor-1 (Egr-1) Biochemical Journal 1998 336 1 183 189 (Pubitemid 28532575)
    • (1998) Biochemical Journal , vol.336 , Issue.1 , pp. 183-189
    • Silverman, E.S.1    Du, J.2    Williams, A.J.3    Wadgaonkar, R.4    Drazen, J.M.5    Collins, T.6
  • 139
    • 0037151065 scopus 로고    scopus 로고
    • The HMG-I/Y-related protein p8 binds to p300 and Pax2 trans-activation domain-interacting protein to regulate the trans-activation activity of the Pax2A and Pax2B transcription factors on the glucagon gene promoter
    • DOI 10.1074/jbc.M201657200
    • Hoffmeister A., Ropolo A., Vasseur S., Mallo G. V., Bodeker H., Ritz-Laser B., Dressler G. R., Vaccaro M. I., Dagorn J. C., Moreno S., Iovanna J. L., The HMG-I/Y-related protein p8 binds to p300 and Pax2 trans-activation domain-interacting protein to regulate the trans-activation activity of the Pax2A and Pax2B transcription factors on the glucagon gene promoter Journal of Biological Chemistry 2002 277 25 22314 22319 (Pubitemid 34967198)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.25 , pp. 22314-22319
    • Hoffmeister, A.1    Ropolo, A.2    Vasseur, S.3    Mallo, G.V.4    Bodeker, H.5    Ritz-Laser, B.6    Dressler, G.R.7    Vaccaro, M.I.8    Dagorn, J.-C.9    Moreno, S.10    Iovanna, J.L.11
  • 140
    • 0037088594 scopus 로고    scopus 로고
    • Cyclin D1 represses the basic helix-loop-helix transcription factor, BETA2/NeuroD
    • DOI 10.1074/jbc.M110747200
    • Ratineau C., Petry M. W., Mutoh H., Leiter A. B., Cyclin D1 represses the basic helix-loop-helix transcription factor, BETA2/NeuroD Journal of Biological Chemistry 2002 277 11 8847 8853 (Pubitemid 34952952)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.11 , pp. 8847-8853
    • Ratineau, C.1    Petry, M.W.2    Mutoh, H.3    Leiter, A.B.4
  • 141
    • 3042801241 scopus 로고    scopus 로고
    • Coactivating factors p300 and CBP are transcriptionally crossregulated by Egr1 in prostate cells, leading to divergent responses
    • DOI 10.1016/j.molcel.2004.06.030, PII S1097276504003533
    • Yu J., de Belle I., Liang H., Adamson E. D., Coactivating factors p300 and CBP are transcriptionally crossregulated by Egr1 in prostate cells, leading to divergent responses Molecular Cell 2004 15 1 83 94 (Pubitemid 38850221)
    • (2004) Molecular Cell , vol.15 , Issue.1 , pp. 83-94
    • Yu, J.1    De Belle, I.2    Liang, H.3    Adamson, E.D.4
  • 142
    • 8844232663 scopus 로고    scopus 로고
    • The RING domain of Mdm2 mediates histone ubiquitylation and transcriptional repression
    • DOI 10.1016/j.molcel.2004.10.016, PII S1097276504006422
    • Minsky N., Oren M., The RING domain of Mdm2 mediates histone ubiquitylation and transcriptional repression Molecular Cell 2004 16 4 631 639 (Pubitemid 39531885)
    • (2004) Molecular Cell , vol.16 , Issue.4 , pp. 631-639
    • Minsky, N.1    Oren, M.2
  • 143
    • 20444423286 scopus 로고    scopus 로고
    • Nuclear interaction of EGFR and STAT3 in the activation of the iNOS/NO pathway
    • DOI 10.1016/j.ccr.2005.05.007, PII S1535610805001583
    • Lo H. W., Hsu S. C., Ali-Seyed M., Gunduz M., Xia W., Wei Y., Bartholomeusz G., Shih J. Y., Hung M. C., Nuclear interaction of EGFR and STAT3 in the activation of the iNOS/NO pathway Cancer Cell 2005 7 6 575 589 (Pubitemid 40799250)
    • (2005) Cancer Cell , vol.7 , Issue.6 , pp. 575-589
    • Lo, H.-W.1    Hsu, S.-C.2    Ali-Seyed, M.3    Gunduz, M.4    Xia, W.5    Wei, Y.6    Bartholomeusz, G.7    Shih, J.-Y.8    Hung, M.-C.9
  • 144
    • 0028875086 scopus 로고
    • Evidence for different modes of action of cyclin-dependent kinase inhibitors: P15 and p16 bind to kinases, p21 and p27 bind to cyclins
    • Hall M., Bates S., Peters G., Evidence for different modes of action of cyclin-dependent kinase inhibitors: p15 and p16 bind to kinases, p21 and p27 bind to cyclins Oncogene 1995 11 8 1581 1588
    • (1995) Oncogene , vol.11 , Issue.8 , pp. 1581-1588
    • Hall, M.1    Bates, S.2    Peters, G.3
  • 145
    • 0032493627 scopus 로고    scopus 로고
    • Cooperative actions of HIV-1 Vpr and p53 modulate viral gene transcription
    • DOI 10.1074/jbc.273.32.20052
    • Sawaya B. E., Khalilit K., Mercer W. E., Denisova L., Amini S., Cooperative actions of HIV-1 Vpr and p53 modulate viral gene transcription Journal of Biological Chemistry 1998 273 32 20052 20057 (Pubitemid 28377557)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.32 , pp. 20052-20057
    • Sawaya, B.E.1    Khalilit, K.2    Mercer, W.E.3    Denisova, L.4    Amini, S.5
  • 146
    • 0031769052 scopus 로고    scopus 로고
    • p53 regulates insulin-like growth factor-I (IGF-I) receptor expression and IGF-I-induced tyrosine phosphorylation in an osteosarcoma cell line: Interaction between p53 and Sp1
    • DOI 10.1210/en.139.3.1101
    • Ohlsson C., Kley N., Werner H., Leroith D., p53 regulates insulin-like growth factor-I (IGF-I) receptor expression and IGF-I-induced tyrosine phosphorylation in an osteosarcoma cell line: interaction between p53 and Sp1 Endocrinology 1998 139 3 1101 1107 (Pubitemid 28510128)
    • (1998) Endocrinology , vol.139 , Issue.3 , pp. 1101-1107
    • Ohlsson, C.1    Kley, N.2    Werner, H.3    Leroith, D.4
  • 147
    • 0037947566 scopus 로고    scopus 로고
    • Suppression of HGF receptor gene expression by oxidative stress is mediated through the interplay between Sp1 and Egr-1
    • Zhang X., Liu Y., Suppression of HGF receptor gene expression by oxidative stress is mediated through the interplay between Sp1 and Egr-1 American Journal of PhysiologyRenal Physiology 2003 284 6 F1216 F1225
    • (2003) American Journal of PhysiologyRenal Physiology , vol.284 , Issue.6
    • Zhang, X.1    Liu, Y.2
  • 149
    • 9744250223 scopus 로고    scopus 로고
    • DNA damage-induced downregulation of Cdc25C is mediated by p53 via two independent mechanisms: One involves direct binding to the cdc25C promoter
    • DOI 10.1016/j.molcel.2004.11.002, PII S1097276504006756
    • Clair S. S., Giono L., Varmeh-Ziaie S., Resnick-Silverman L., Liu W. J., Padi A., Dastidar J., DaCosta A., Mattia M., Manfredi J. J., DNA damage-induced downregulation of Cdc25C is mediated by p53 via two independent mechanisms: one involves direct binding to the cdc25C promoter Molecular Cell 2004 16 5 725 736 (Pubitemid 39586531)
    • (2004) Molecular Cell , vol.16 , Issue.5 , pp. 725-736
    • Clair, S.St.1    Giono, L.2    Varmeh-Ziaie, S.3    Resnick-Silverman, L.4    Liu, W.-J.5    Padi, A.6    Dastidar, J.7    DaCosta, A.8    Mattia, M.9    Manfredi, J.J.10
  • 152
    • 38549157970 scopus 로고    scopus 로고
    • The C terminus of the synovial sarcoma-associated SSX proteins interacts with the LIM homeobox protein LHX4
    • DOI 10.1038/sj.onc.1210688, PII 1210688
    • de Bruijn D. R. H., van Dijk A. H. A., Willemse M. P., van Kessel A. G., The C terminus of the synovial sarcoma-associated SSX proteins interacts with the LIM homeobox protein LHX4 Oncogene 2008 27 5 653 662 (Pubitemid 351158898)
    • (2008) Oncogene , vol.27 , Issue.5 , pp. 653-662
    • De Bruijn, D.R.H.1    Van Dijk, A.H.A.2    Willemse, M.P.3    Van Kessel, A.G.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.