The cancer-related protein SSX2 interacts with the human homologue of a Ras-like GTPase interactor, RAB3IP, and a novel nuclear protein, SSX2IP

Genes Chromosomes and Cancer

Volumn 34, Issue 3, 2002, Pages 285-298

  De Bruijn, Diederik R H ^a   Dos Santos, Nuno R ^a   Kater Baats, Ellen ^a   Thijssen, José ^a   Van Den Berk, Lieke ^a   Stap, Jiska ^a   Balemans, Matthé ^a   Schepens, Marga ^a   Merkx, Gerard ^a   Van Kessel, Ad Geurts ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

GUANOSINE TRIPHOSPHATASE; NUCLEAR PROTEIN; RAB PROTEIN;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CHROMOSOME TRANSLOCATION; DNA LIBRARY; GENE PROBE; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; MULTIGENE FAMILY; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; TRANSCRIPTION REGULATION; TWO HYBRID SYSTEM;

ADULT; CARRIER PROTEINS; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 1; CHROMOSOMES, HUMAN, PAIR 12; FETUS; GENE LIBRARY; HELA CELLS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MOLECULAR SEQUENCE DATA; NEOPLASM PROTEINS; NUCLEAR PROTEINS; PEPTIDES; RAB3A GTP-BINDING PROTEIN; REPRESSOR PROTEINS; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY, AMINO ACID; TESTIS; TUMOR CELLS, CULTURED; TWO-HYBRID SYSTEM TECHNIQUES;

EID: 18444412567     PISSN: 10452257     EISSN: None     Source Type: Journal    
DOI: 10.1002/gcc.10073     Document Type: Article

References (48)

1. Gapped BLAST and PSI-BLAST: A new generation of protein database search programs
2. The SWISS-PROT protein sequence data bank and its supplement TrEMBL in 1999
3. The PROSITE database: Its status in 1997
4. dbEST - Database for "expressed sequence tags"
5. The SYT protein involved in the t(X;18) synovial sarcoma translocation is a transcriptional activator localised in nuclear bodies
6. Interaction cloning of Rabin3, a novel protein that associates with the Ras-like GTPase Rab3A
7. Long-range organization of reiterated sequences, including the SSX1 cDNA, at the OATL1 cluster in Xp11.23
8. Cytogenetic analysis of 363 consecutively ascertained diffuse large B-cell lymphomas
9. Identification of novel genes, SYT and SSX, involved in the t(X;18)(p11.2;q11.2) translocation found in human synovial sarcoma
10. Transcript mapping of the human chromosome 11q12-q13.1 gene-rich region identifies several newly described conserved genes
11. Fusion of SYT to two genes, SSX1 and SSX2, encoding proteins with homology to the Krüppel-associated box in human synovial sarcoma
12. Association of the GTP-binding protein Rab3A with bovine adrenal chromaffin granules
13. Isolation and characterization of the mouse homolog of SYT, a gene implicated in the development of human synovial sarcomas
14. The synovial sarcoma associated protein SYT interacts with the acute leukemia associated protein AF10
15. Mapping and characterization of the mouse and human SS18 genes, two human SS18-like genes and a mouse Ss18 pseudogene
16. Identification of two alternative fusion genes, SYT-SSX1 and SYT-SSX2, in t(X,18)(p11.2, q11.2)-positive synovial sarcomas
17. A novel Krüppel-associated box containing SSX gene (SSX3) on the human X chromosome is not implicated in t(X;18)-positive synovial sarcomas
18. Nuclear localization of SYT, SSX and the synovial sarcoma-associated SYT-SSX fusion proteins
19. Heterogeneous expression of the SSX cancer/testis antigens in human melanoma lesions and cell lines
20. Delineation of the protein domains responsible for SYT, SSX and SYT-SSX nuclear localization
21. Molecular mechanisms underlying human synovial sarcoma development
22. Analysis of the sheep tricohyalin gene: Potential structural and calcium-binding roles of tricohyalin in the hair follicle
23. Molecular diagnosis of synovial sarcoma and characterization of a variant SYT-SSX2 fusion transcript
24. Mapping of amplification units in the q13-14 region of chromosome 12 in human sarcomas: Some amplica do not include MDM2
25. Two versatile eukaryotic expression vectors permitting epitope tagging, radiolabelling and nuclear localisation of expressed proteins
26. SOPMA: Significant improvements in protein secondary structure prediction by consensus prediction from multiple alignments
27. SSX: A multigene family with several members transcribed in normal testis and human cancer
28. DNA copy number amplifications in human neoplasms: Review of comparative genomic hybridization studies
29. DNA copy number losses in human neoplasms
30. A KRAB-related domain and a novel transcription repression domain in proteins encoded by SSX genes that are disrupted in human sarcomas
31. GRAB: A physiologic guanine nucleotide exchange factor for Rab3A, which interacts with inositol hexakisphosphate kinase
32. Predicting coiled-coils from protein sequences
33. Three major cytogenetic subgroups can be identified among chromosomally abnormal solitary lipomas
34. Krüppel-associated boxes are potent transcriptional repressor domains
35. A catalogue of splice junction sequences
36. Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro
37. Sec2 protein contains a coiled-coil domain essential for vesicular transport and a dispensable carboxyl terminal domain
38. PSORT: A program for detecting sorting signals in proteins and predicting their subcellular localization
39. Improved tools for biological sequence comparison
40. Characterization of a variant SYT-SSX1 synovial sarcoma fusion transcript
41. A novel fusion gene, SYT-SSX4, in synovial sarcoma
42. SSX and the synovial sarcoma specific chimaeric protein SYT-SSX co-localize with the human polycomb group complex
43. Demonstration of the genuine iso(12p) character of the standard marker chromosome of testicular germ cell tumors and identification of further chromosome 12 aberrations by competitive in situ hybridisation
44. The SSX-2 gene, which is involved in the t(X,18) translocation of synovial sarcomas, codes for the human tumor antigen HOM-MEL 40
45. Expression of SSX genes in human tumors
46. 2.2 Mb of contiguous nucleotide sequence from chromosome III of C. elegans
47. A new strategy of gene trapping in ES cells using 3′ RACE