메뉴 건너뛰기




Volumn 193, Issue 1, 2009, Pages 1-8

Molecular and immunohistochemical analyses of BCL2, KI-67, and cyclin D1 expression in synovial sarcoma

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN D1; KI 67 ANTIGEN; MESSENGER RNA; PROTEIN BCL 2; CCND1 PROTEIN, HUMAN; RNA;

EID: 67651094040     PISSN: 01654608     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cancergencyto.2009.03.008     Document Type: Article
Times cited : (18)

References (34)
  • 1
    • 0027933151 scopus 로고
    • Identification of novel genes, SYT and SSX, involved in the t(X;18)(p11.2;q11.2) translocation found in human synovial sarcoma
    • Clark J., Rocques P.J., Crew A.J., Gill S., Shipley J., Chan A.M., Gusterson B.A., and Cooper C.S. Identification of novel genes, SYT and SSX, involved in the t(X;18)(p11.2;q11.2) translocation found in human synovial sarcoma. Nat Genet 7 (1994) 502-508
    • (1994) Nat Genet , vol.7 , pp. 502-508
    • Clark, J.1    Rocques, P.J.2    Crew, A.J.3    Gill, S.4    Shipley, J.5    Chan, A.M.6    Gusterson, B.A.7    Cooper, C.S.8
  • 2
    • 0029066330 scopus 로고
    • Fusion of SYT to two genes, SSX1 and SSX2, encoding proteins with homology to the Kruppel-associated box in human synovial sarcoma
    • Crew A.J., Clark J., Fisher C., Gill S., Grimer R., Chand A., Shipley J., Gusterson B.A., and Cooper C.S. Fusion of SYT to two genes, SSX1 and SSX2, encoding proteins with homology to the Kruppel-associated box in human synovial sarcoma. EMBO J 14 (1995) 2333-2340
    • (1995) EMBO J , vol.14 , pp. 2333-2340
    • Crew, A.J.1    Clark, J.2    Fisher, C.3    Gill, S.4    Grimer, R.5    Chand, A.6    Shipley, J.7    Gusterson, B.A.8    Cooper, C.S.9
  • 3
    • 0033168038 scopus 로고    scopus 로고
    • The SYT-SSX1 variant of synovial sarcoma is associated with a high rate of tumor cell proliferation and poor clinical outcome
    • Nilsson G., Skytting B., Xie Y., Brodin B., Perfekt R., Mandahl N., Lundeberg J., Uhlén M., and Larsson O. The SYT-SSX1 variant of synovial sarcoma is associated with a high rate of tumor cell proliferation and poor clinical outcome. Cancer Res 59 (1999) 3180-3184
    • (1999) Cancer Res , vol.59 , pp. 3180-3184
    • Nilsson, G.1    Skytting, B.2    Xie, Y.3    Brodin, B.4    Perfekt, R.5    Mandahl, N.6    Lundeberg, J.7    Uhlén, M.8    Larsson, O.9
  • 4
    • 0034078438 scopus 로고    scopus 로고
    • Association of SYT-SSX fusion types with proliferative activity and prognosis in synovial sarcoma
    • Inagaki H., Nagasaka T., Otsuka T., Sugiura E., Nakashima N., and Eimoto T. Association of SYT-SSX fusion types with proliferative activity and prognosis in synovial sarcoma. Mod Pathol 13 (2000) 482-488
    • (2000) Mod Pathol , vol.13 , pp. 482-488
    • Inagaki, H.1    Nagasaka, T.2    Otsuka, T.3    Sugiura, E.4    Nakashima, N.5    Eimoto, T.6
  • 5
    • 1642618055 scopus 로고    scopus 로고
    • Molecular and pharmacokinetic properties associated with the therapeutics of bcl-2 antisense oligonucleotide G3139 combined with free and liposomal doxorubicin
    • Lopes de Menezes D.E., Hudon N., McIntosh N., and Mayer L.D. Molecular and pharmacokinetic properties associated with the therapeutics of bcl-2 antisense oligonucleotide G3139 combined with free and liposomal doxorubicin. Clin Cancer Res 6 (2000) 2891-2902
    • (2000) Clin Cancer Res , vol.6 , pp. 2891-2902
    • Lopes de Menezes, D.E.1    Hudon, N.2    McIntosh, N.3    Mayer, L.D.4
  • 6
    • 0037171581 scopus 로고    scopus 로고
    • Apoptosis and expression of its regulatory proteins in soft tissue sarcomas
    • Dan'ura T., Kawai A., Morimoto Y., Naito N., Yoshida A., and Inoue H. Apoptosis and expression of its regulatory proteins in soft tissue sarcomas. Cancer Lett 178 (2002) 167-174
    • (2002) Cancer Lett , vol.178 , pp. 167-174
    • Dan'ura, T.1    Kawai, A.2    Morimoto, Y.3    Naito, N.4    Yoshida, A.5    Inoue, H.6
  • 7
    • 0031691804 scopus 로고    scopus 로고
    • Histopathological evaluation of apoptosis in cancer
    • Soini Y., Pääkkö P., and Lehto V.P. Histopathological evaluation of apoptosis in cancer. Am J Pathol 153 (1998) 1041-1053
    • (1998) Am J Pathol , vol.153 , pp. 1041-1053
    • Soini, Y.1    Pääkkö, P.2    Lehto, V.P.3
  • 8
    • 0024501122 scopus 로고
    • The bcl-2 candidate proto-oncogene product is a 24-kilodalton integral-membrane protein highly expressed in lymphoid cell lines and lymphomas carrying the t(14;18) translocation
    • Chen-Levy Z., Nourse J., and Cleary M.L. The bcl-2 candidate proto-oncogene product is a 24-kilodalton integral-membrane protein highly expressed in lymphoid cell lines and lymphomas carrying the t(14;18) translocation. Mol Cell Biol 9 (1989) 701-710
    • (1989) Mol Cell Biol , vol.9 , pp. 701-710
    • Chen-Levy, Z.1    Nourse, J.2    Cleary, M.L.3
  • 10
    • 0028930969 scopus 로고
    • What is the value of bcl-2 protein detection for histopathologists?
    • Pezzella F., and Gatter K. What is the value of bcl-2 protein detection for histopathologists?. Histopathology 26 (1995) 89-93
    • (1995) Histopathology , vol.26 , pp. 89-93
    • Pezzella, F.1    Gatter, K.2
  • 11
    • 0027757091 scopus 로고
    • Expression of the apoptosis-suppressing protein bcl-2, in neuroblastoma is associated with unfavorable histology and N-myc amplification
    • Castle V.P., Heidelberger K.P., Bromberg J., Ou X., Dole M., and Nuñez G. Expression of the apoptosis-suppressing protein bcl-2, in neuroblastoma is associated with unfavorable histology and N-myc amplification. Am J Pathol 143 (1993) 1543-1550
    • (1993) Am J Pathol , vol.143 , pp. 1543-1550
    • Castle, V.P.1    Heidelberger, K.P.2    Bromberg, J.3    Ou, X.4    Dole, M.5    Nuñez, G.6
  • 12
    • 0033041289 scopus 로고    scopus 로고
    • Detection of SYT-SSX fusion transcript in synovial sarcoma using archival cytologic specimens
    • Inagaki H., Murase T., Otsuka T., and Eimoto T. Detection of SYT-SSX fusion transcript in synovial sarcoma using archival cytologic specimens. Am J Clin Pathol 111 (1999) 528-533
    • (1999) Am J Clin Pathol , vol.111 , pp. 528-533
    • Inagaki, H.1    Murase, T.2    Otsuka, T.3    Eimoto, T.4
  • 13
    • 0035136377 scopus 로고    scopus 로고
    • Quantitative real-time reverse transcription-PCR assay for cyclin D1 expression: utility in the diagnosis of mantle cell lymphoma
    • Bijwaard K.E., Aguilera N.S., Monczak Y., Trudel M., Taubenberger J.K., and Lichy J.H. Quantitative real-time reverse transcription-PCR assay for cyclin D1 expression: utility in the diagnosis of mantle cell lymphoma. Clin Chem 47 (2001) 195-201
    • (2001) Clin Chem , vol.47 , pp. 195-201
    • Bijwaard, K.E.1    Aguilera, N.S.2    Monczak, Y.3    Trudel, M.4    Taubenberger, J.K.5    Lichy, J.H.6
  • 14
    • 0033014030 scopus 로고    scopus 로고
    • In vivo patterns of Bcl-2 family protein expression in breast carcinomas in relation to apoptosis
    • Rochaix P., Krajewski S., Reed J.C., Bonnet F., Voigt J.J., and Brousset P. In vivo patterns of Bcl-2 family protein expression in breast carcinomas in relation to apoptosis. J Pathol 187 (1999) 410-415
    • (1999) J Pathol , vol.187 , pp. 410-415
    • Rochaix, P.1    Krajewski, S.2    Reed, J.C.3    Bonnet, F.4    Voigt, J.J.5    Brousset, P.6
  • 15
    • 0028960205 scopus 로고
    • Tumor type is a determinant of susceptibility to apoptosis
    • Staunton M.J., and Gaffney E.F. Tumor type is a determinant of susceptibility to apoptosis. Am J Clin Pathol 103 (1995) 300-307
    • (1995) Am J Clin Pathol , vol.103 , pp. 300-307
    • Staunton, M.J.1    Gaffney, E.F.2
  • 16
    • 18244421887 scopus 로고    scopus 로고
    • Prognostic significance of apoptosis in synovial sarcoma: correlation with clinicopathologic parameters, cell proliferative activity, and expression of apoptosis-related proteins
    • Kawauchi S., Fukuda T., Oda Y., Saito T., Oga A., Takeshita M., Yokoyama K., Chuman H., Iwamoto Y., Sasaki K., and Tsuneyoshi M. Prognostic significance of apoptosis in synovial sarcoma: correlation with clinicopathologic parameters, cell proliferative activity, and expression of apoptosis-related proteins. Mod Pathol 13 (2000) 755-765
    • (2000) Mod Pathol , vol.13 , pp. 755-765
    • Kawauchi, S.1    Fukuda, T.2    Oda, Y.3    Saito, T.4    Oga, A.5    Takeshita, M.6    Yokoyama, K.7    Chuman, H.8    Iwamoto, Y.9    Sasaki, K.10    Tsuneyoshi, M.11
  • 17
    • 0030993852 scopus 로고    scopus 로고
    • Immunohistochemical detection of bcl-2 and p53 proteins and apoptosis in soft tissue sarcoma: their correlations with prognosis
    • Nakanishi H., Ohsawa M., Naka N., Uchida A., Ochi T., and Aozasa K. Immunohistochemical detection of bcl-2 and p53 proteins and apoptosis in soft tissue sarcoma: their correlations with prognosis. Oncology 54 (1997) 238-244
    • (1997) Oncology , vol.54 , pp. 238-244
    • Nakanishi, H.1    Ohsawa, M.2    Naka, N.3    Uchida, A.4    Ochi, T.5    Aozasa, K.6
  • 18
    • 0028040019 scopus 로고
    • Bcl-2 and the regulation of programmed cell death
    • Reed J.C. Bcl-2 and the regulation of programmed cell death. J Cell Biol 124 (1994) 1-6
    • (1994) J Cell Biol , vol.124 , pp. 1-6
    • Reed, J.C.1
  • 19
    • 0027246692 scopus 로고
    • Regulation by bcl-2, c-myc, and p53 of susceptibility to induction of apoptosis by heat shock and cancer chemotherapy compounds in differentiation-competent and -defective myeloid leukemic cells
    • Lotem J., and Sachs L. Regulation by bcl-2, c-myc, and p53 of susceptibility to induction of apoptosis by heat shock and cancer chemotherapy compounds in differentiation-competent and -defective myeloid leukemic cells. Cell Growth Differ 4 (1993) 41-47
    • (1993) Cell Growth Differ , vol.4 , pp. 41-47
    • Lotem, J.1    Sachs, L.2
  • 20
    • 0027513548 scopus 로고
    • Expression of BCL-2 protein enhances the survival of mouse fibrosarcoid cells in tumor necrosis factor-mediated cytotoxicity
    • Hennet T., Bertoni G., Richter C., and Peterhans E. Expression of BCL-2 protein enhances the survival of mouse fibrosarcoid cells in tumor necrosis factor-mediated cytotoxicity. Cancer Res 53 (1993) 1456-1460
    • (1993) Cancer Res , vol.53 , pp. 1456-1460
    • Hennet, T.1    Bertoni, G.2    Richter, C.3    Peterhans, E.4
  • 22
    • 0030864083 scopus 로고    scopus 로고
    • Establishment and characterization of a new synovial sarcoma cell line, SN-SY-1: special reference to bcl-2 protein and SYT-SSX1 hybrid transcripts
    • Noguchi S.I., Ueki T., Kawauchi S., Fukuda T., Matsuura H., Sonoda T., and Tsuneyoshi M. Establishment and characterization of a new synovial sarcoma cell line, SN-SY-1: special reference to bcl-2 protein and SYT-SSX1 hybrid transcripts. Int J Cancer 72 (1997) 995-1002
    • (1997) Int J Cancer , vol.72 , pp. 995-1002
    • Noguchi, S.I.1    Ueki, T.2    Kawauchi, S.3    Fukuda, T.4    Matsuura, H.5    Sonoda, T.6    Tsuneyoshi, M.7
  • 24
    • 0031672093 scopus 로고    scopus 로고
    • Cell-type- and tumour-type-related patterns of bcl-2 reactivity in mesenchymal cells and soft tissue tumours
    • Miettinen M., Sarlomo-Rikala M., and Kovatich A.J. Cell-type- and tumour-type-related patterns of bcl-2 reactivity in mesenchymal cells and soft tissue tumours. Virchows Arch 433 (1998) 255-260
    • (1998) Virchows Arch , vol.433 , pp. 255-260
    • Miettinen, M.1    Sarlomo-Rikala, M.2    Kovatich, A.J.3
  • 26
    • 0029859402 scopus 로고    scopus 로고
    • Overexpression of bcl-2 protein in synovial sarcoma: a comparative study of other soft tissue spindle cell sarcomas and an additional analysis by fluorescence in situ hybridization
    • Hirakawa N., Naka T., Yamamoto I., Fukuda T., and Tsuneyoshi M. Overexpression of bcl-2 protein in synovial sarcoma: a comparative study of other soft tissue spindle cell sarcomas and an additional analysis by fluorescence in situ hybridization. Hum Pathol 27 (1996) 1060-1065
    • (1996) Hum Pathol , vol.27 , pp. 1060-1065
    • Hirakawa, N.1    Naka, T.2    Yamamoto, I.3    Fukuda, T.4    Tsuneyoshi, M.5
  • 28
    • 0030969478 scopus 로고    scopus 로고
    • Overexpression of cyclin D1 in human pancreatic carcinoma is associated with poor prognosis
    • Gansauge S., Gansauge F., Ramadani M., Stobbe H., Rau B., Harada N., and Beger H.G. Overexpression of cyclin D1 in human pancreatic carcinoma is associated with poor prognosis. Cancer Res 57 (1997) 1634-1637
    • (1997) Cancer Res , vol.57 , pp. 1634-1637
    • Gansauge, S.1    Gansauge, F.2    Ramadani, M.3    Stobbe, H.4    Rau, B.5    Harada, N.6    Beger, H.G.7
  • 29
    • 0028953560 scopus 로고
    • Overexpression of cyclin D1 correlates with recurrence in a group of forty-seven operable squamous cell carcinomas of the head and neck
    • Michalides R., van Veelen N., Hart A., Loftus B., Wientjens E., and Balm A. Overexpression of cyclin D1 correlates with recurrence in a group of forty-seven operable squamous cell carcinomas of the head and neck. Cancer Res 55 (1995) 975-978
    • (1995) Cancer Res , vol.55 , pp. 975-978
    • Michalides, R.1    van Veelen, N.2    Hart, A.3    Loftus, B.4    Wientjens, E.5    Balm, A.6
  • 30
    • 0033902014 scopus 로고    scopus 로고
    • Alterations of cell cycle regulators in localized synovial sarcoma: a multifactorial study with prognostic implications
    • Antonescu C.R., Leung D.H., Dudas M., Ladanyi M., Brennan M., Woodruff J.M., and Cordon-Cardo C. Alterations of cell cycle regulators in localized synovial sarcoma: a multifactorial study with prognostic implications. Am J Pathol 156 (2000) 977-983
    • (2000) Am J Pathol , vol.156 , pp. 977-983
    • Antonescu, C.R.1    Leung, D.H.2    Dudas, M.3    Ladanyi, M.4    Brennan, M.5    Woodruff, J.M.6    Cordon-Cardo, C.7
  • 31
    • 0028967830 scopus 로고
    • Cyclin D1 oncoprotein aberrantly accumulates in malignancies of diverse histogenesis
    • Bartkova J., Lukas J., Strauss M., and Bartek J. Cyclin D1 oncoprotein aberrantly accumulates in malignancies of diverse histogenesis. Oncogene 10 (1995) 775-778
    • (1995) Oncogene , vol.10 , pp. 775-778
    • Bartkova, J.1    Lukas, J.2    Strauss, M.3    Bartek, J.4
  • 33
    • 0036645310 scopus 로고    scopus 로고
    • SYT-SSX is critical for cyclin D1 expression in synovial sarcoma cells: a gain of function of the t(X;18)(p11.2;q11.2) translocation
    • Xie Y., Skytting B., Nilsson G., Gasbarri A., Haslam K., Bartolazzi A., Brodin B., Mandahl N., and Larsson O. SYT-SSX is critical for cyclin D1 expression in synovial sarcoma cells: a gain of function of the t(X;18)(p11.2;q11.2) translocation. Cancer Res 62 (2002) 3861-3867
    • (2002) Cancer Res , vol.62 , pp. 3861-3867
    • Xie, Y.1    Skytting, B.2    Nilsson, G.3    Gasbarri, A.4    Haslam, K.5    Bartolazzi, A.6    Brodin, B.7    Mandahl, N.8    Larsson, O.9
  • 34
    • 0034725690 scopus 로고    scopus 로고
    • Oncogenic Ras-mediated cell growth arrest and apoptosis are associated with increased ubiquitin-dependent cyclin D1 degradation
    • Shao J., Sheng H., DuBois R.N., and Beauchamp R.D. Oncogenic Ras-mediated cell growth arrest and apoptosis are associated with increased ubiquitin-dependent cyclin D1 degradation. J Biol Chem 275 (2000) 22916-22924
    • (2000) J Biol Chem , vol.275 , pp. 22916-22924
    • Shao, J.1    Sheng, H.2    DuBois, R.N.3    Beauchamp, R.D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.