Comprehensive phosphoproteome analysis of INS-1 pancreatic beta-cells using various digestion strategies coupled with liquid chromatography-tandem mass spectrometry

Journal of Proteome Research

Volumn 11, Issue 4, 2012, Pages 2206-2223

  Han, Dohyun ^a,b   Moon, Sungyoon ^a   Kim, Yikwon ^a   Ho, Won Kyung ^b   Kim, Kyunggon ^a,b   Kang, Yup ^c   Jun, Heesook ^d   Kim, Youngsoo ^a,b  

^a Seoul National University   (South Korea)

^b Seoul National University College of Medicine   (South Korea)

^c Ajou University School of Medicine   (South Korea)

^d Gachon University College of Medicine   (South Korea)

Author keywords

beta cell; diabetes; INS 1 cell; phosphoproteome; phosphoproteomics

Indexed keywords

DETERGENT; PHOSPHOPROTEIN; PROTEOME; TITANIUM DIOXIDE; TRANSCRIPTION FACTOR NKX2.2; TRANSCRIPTION FACTOR PDX 1;

ANIMAL CELL; ARTICLE; BIOINFORMATICS; CELL LINE; CELL LYSATE; CONTROLLED STUDY; HUMAN; INSULINOMA; LIQUID CHROMATOGRAPHY; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEOMICS; RAT; TANDEM MASS SPECTROMETRY; VALIDATION STUDY;

AMINO ACID SEQUENCE; ANIMALS; CELL LINE; CHROMATOGRAPHY, LIQUID; DATABASES, PROTEIN; INSULIN-SECRETING CELLS; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN KINASES; PROTEOME; PROTEOMICS; RATS; SEQUENCE ALIGNMENT; SIGNAL TRANSDUCTION; TANDEM MASS SPECTROMETRY;

RATTUS;

EID: 84859586780     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr200990b     Document Type: Article

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