STAT3 regulates monocyte TNF-alpha production in systemic inflammation caused by cardiac surgery with cardiopulmonary bypass

PLoS ONE

Volumn 7, Issue 4, 2012, Pages

  de Jong, Petrus R ^a   Schadenberg, Alvin W L ^a   van den Broek, Theo ^a   Beekman, Jeffrey M ^b   van Wijk, Femke ^a   Coffer, Paul J ^a,b   Prakken, Berent J ^a   Jansen, Nicolaas J G ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

DEXAMETHASONE; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE P38; STAT3 PROTEIN; TUMOR NECROSIS FACTOR ALPHA; I KAPPA B KINASE; IL10 PROTEIN, HUMAN; IL6 PROTEIN, HUMAN; STAT3 PROTEIN, HUMAN;

ARTICLE; CARDIOPULMONARY BYPASS; CHILD; CLINICAL ARTICLE; CONGENITAL HEART MALFORMATION; CYTOKINE PRODUCTION; DOWN REGULATION; EX VIVO STUDY; FEMALE; FLOW CYTOMETRY; HEART SURGERY; HUMAN; HUMAN CELL; INFLAMMATION; INNATE IMMUNITY; MALE; MONOCYTE; PERIPHERAL BLOOD MONONUCLEAR CELL; SCHOOL CHILD; WESTERN BLOTTING; BIOSYNTHESIS; BLOOD; DRUG EFFECT; IMMUNOLOGY; METABOLISM; METHODOLOGY; MONONUCLEAR CELL; SIGNAL TRANSDUCTION; THORAX SURGERY;

CARDIOPULMONARY BYPASS; CHILD; FEMALE; HUMANS; I-KAPPA B KINASE; IMMUNITY, INNATE; INFLAMMATION; INTERLEUKIN-10; INTERLEUKIN-6; LEUKOCYTES, MONONUCLEAR; LIPOPOLYSACCHARIDES; MALE; MONOCYTES; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; THORACIC SURGERY; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84859575047     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0035070     Document Type: Article

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