ST2 suppresses IL-6 production via the inhibition of IκB degradation induced by the LPS signal in THP-1 cells

Biochemical and Biophysical Research Communications

Volumn 341, Issue 2, 2006, Pages 425-432

  Takezako, Naoki ^a   Hayakawa, Morisada ^a   Hayakawa, Hiroko ^a   Aoki, Shinsuke ^a   Yanagisawa, Ken ^a   Endo, Hitoshi ^a   Tominaga, Shin Ichi ^a  

^a JICHI MEDICAL UNIVERSITY   (Japan)

Author keywords

I B ; IL 6; Inflammatory cytokines; LPS; NF B; Soluble secreted ST2; THP 1; TLR4

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; ST2 GENE; UNCLASSIFIED DRUG;

ARTICLE; CONFOCAL MICROSCOPY; CYTOPLASM; ENZYME INHIBITION; GENE REPRESSION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; LEUKEMIA CELL LINE; MONOCYTIC LEUKEMIA; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION;

BLOTTING, WESTERN; CELL LINE; CELL NUCLEUS; CYTOPLASM; DNA, COMPLEMENTARY; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION REGULATION; HUMANS; I-KAPPA B PROTEINS; IMMUNOPRECIPITATION; INTERLEUKIN-1; INTERLEUKIN-6; LAC OPERON; LIPOPOLYSACCHARIDES; MEMBRANE PROTEINS; MICROSCOPY, CONFOCAL; MICROSCOPY, FLUORESCENCE; MODELS, STATISTICAL; MONOCYTES; PLASMIDS; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; RECEPTORS, CELL SURFACE; RECOMBINANT PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SILVER STAINING; TOLL-LIKE RECEPTOR 4; TRANSFECTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 31444440401     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2005.12.206     Document Type: Article

References (23)

1. S. Tominaga A putative protein of a growth specific cDNA from BALB/c-3T3 cells is highly similar to the extracellular portion of mouse interleukin 1 receptor FEBS Lett. 258 1989 301 304
2. K. Yanagisawa, Y. Naito, K. Kuroiwa, T. Arai, Y. Furukawa, H. Tomizuka, Y. Miura, T. Kasahara, T. Tetsuka, and S. Tominaga The expression of ST2 gene in helper T cells and the binding of ST2 protein to myeloma-derived RPMI8226 cells J. Biochem. (Tokyo) 121 1997 95 103
3. D. Xu, W. Chan, B. Leung, F. Huang, R. Wheeler, D. Piedrafita, J. Robinson, and F. Liew Selective expression of a stable cell surface molecule on type 2 but not type 1 helper T cells J. Exp. Med. 187 1998 787 794
4. M. Löhning, A. Stroehmann, A. Coyle, J. Grogan, S. Lin, J. Gutierrez-Ramos, D. Levinson, A. Radbruch, and T. Kamradt T1/ST2 is preferentially expressed on murine Th2 cells, independent of interleukin 4, interleukin 5, and interleukin 10, and important for Th2 effector function Proc. Natl. Acad. Sci. USA 95 1998 6930 6935
5. K. Yanagisawa, T. Takagi, T. Tsukamoto, T. Tetsuka, and S. Tominaga Presence of a novel primary response gene ST2L, encoding a product highly similar to the interleukin 1 receptor type 1 FEBS Lett. 318 1993 83 87
6. M. Sweet, B. Leung, D. Kang, M. Sogaard, K. Schulz, V. Trajkovic, C. Campbell, D. Xu, and F. Liew A novel pathway regulating lipopolysaccharide- induced shock by ST2/T1 via inhibition of Toll-like receptor 4 expression J. Immunol. 166 2001 6633 6639
7. K. Takeda, T. Kaisho, and S. Akira Toll-like receptors Annu. Rev. Immunol. 21 2003 335 376
8. D.N. Cook, D.S. Pisetsky, and D.A. Schwartz Toll-like receptors in the pathogenesis of human disease Nat. Immunol. 5 2004 975 979
9. S. Akira, K. Takeda, and T. Kaisho Toll-like receptors: critical proteins linking innate and acquired immunity Nat. Immunol. 2 2001 675 680
10. A. Poltorak, X. He, I. Smirnova, M.Y. Liu, C. Van Huffel, X. Du, D. Birdwell, E. Alejos, M. Silva, C. Galanos, M. Freudenberg, P. Ricciardi-Castagnoli, B. Layton, and B. Beutler Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene Science 282 1998 2085 2088
11. R. Medzhitov, P. Preston-Hurlburt, and C.A. Janeway Jr. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity Nature 388 1997 394 397
12. M. Yamamoto, K. Takeda, and S. Akira TIR domain-containing adaptors define the specificity of TLR signaling Mol. Immunol. 40 2004 861 868
13. M. Karin, and A. Lin NF-κB at the crossroads of life and death Nat. Immunol. 3 2002 221 227
14. M. Goto, K. Katayama, F. Shirakawa, and I. Tanaka Involvement of NF-kappaB p50/p65 heterodimer in activation of the human pro-interleukin-1beta gene at two subregions of the upstream enhancer element Cytokine 11 1999 16 28
15. A. Baldwin The NF-kappa B and I kappa B proteins: new discoveries and insights Annu. Rev. Immunol. 14 1996 649 683
16. M. Jacobs, and S. Harrison Structure of an I kappa B alpha/NF-kappa B complex Cell 95 1998 749 758
17. J. Schletter, H. Heine, A. Ulmer, and E. Rietschel Molecular mechanisms of endotoxin activity Arch. Microbiol. 164 1995 383 389
18. S. Tsuchiya, M. Yamabe, Y. Yamaguchi, Y. Kobayashi, T. Konno, and K. Tada Establishment and characterization of a human acute monocytic leukemia cell line (THP-1) Int. J. Cancer 26 1980 171 176
19. S. Tsuchiya, Y. Kobayashi, Y. Goto, H. Okumura, S. Nakae, T. Konno, and K. Tada Induction of maturation in cultured human monocytic leukemia cells by a phorbol diester Cancer Res. 42 1982 1530 1536
20. C. Chen, and H. Okayama High-efficiency transformation of mammalian cells by plasmid DNA Mol. Cell. Biol. 7 1987 2745 2752
21. K. Kuroiwa, H. Li, K. Tago, H. Iwahana, K. Yanagisawa, N. Komatsu, K. Oshikawa, Y. Sugiyama, T. Arai, and S. Tominaga Construction of ELISA system to quantify human ST2 protein in sera of patients Hybridoma 19 2000 151 159
22. M. Hayakawa, K. Yanagisawa, S. Aoki, H. Hayakawa, N. Takezako, and S. Tominaga T-helper type 2 cell-specific expression of the ST2 gene is regulated by transcription factor GATA-3 Biochim. Biophys. Acta 1728 2005 53 64
23. K. Oshikawa, K. Yanagisawa, S. Tominaga, and Y. Sugiyama ST2 protein induced by inflammatory stimuli can modulate acute lung inflammation Biochem. Biophys. Res. Commun. 299 2002 18 24