In vivo activity and duration of short interfering RNAs containing a synthetic 5′-phosphate

Nucleic Acid Therapeutics

Volumn 22, Issue 2, 2012, Pages 90-95

  Kenski, Denise M ^a   Willingham, Aarron T ^a   Haringsma, Henry J ^a   Li, Jenny J ^a   Flanagan, W Michael ^a  

^a Sirna Therapeutics Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5' PHOSPHATE; MESSENGER RNA; NANOPARTICLE; PHOSPHATE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CHEMICAL MODIFICATION; CONTROLLED STUDY; DRUG ACTIVITY; DRUG FORMULATION; DRUG POTENCY; GENE SILENCING; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PHOSPHORYLATION; PRIORITY JOURNAL; RNA DEGRADATION;

ANIMALS; APOLIPOPROTEINS B; BASE SEQUENCE; CELL LINE; GENES, REPORTER; LUCIFERASES; MALE; MICE; MICE, INBRED C57BL; PHOSPHATES; PROCOLLAGEN-PROLINE DIOXYGENASE; PROMOTER REGIONS, GENETIC; RNA INTERFERENCE; RNA STABILITY; RNA, MESSENGER; RNA, SMALL INTERFERING;

EID: 84859515193     PISSN: 21593337     EISSN: None     Source Type: Journal    
DOI: 10.1089/nat.2011.0333     Document Type: Article

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