Exposure to ozone modulates human airway protease/antiprotease balance contributing to increased influenza a infection

PLoS ONE

Volumn 7, Issue 4, 2012, Pages

  Kesic, Matthew J ^a   Meyer, Megan ^a   Bauer, Rebecca ^a,b   Jaspers, Ilona ^a,b  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT; HUMAN AIRWAY TRYPSIN LIKE PROTEASE; INFLUENZA VIRUS HEMAGGLUTININ; OZONE; PROTEINASE; PROTEINASE INHIBITOR; TRANSMEMBRANE PROTEASE SERINE 2; TYPE II TRANSMEMBRANE SERINE PROTEASE; UNCLASSIFIED DRUG; PEPTIDE HYDROLASE; SECRETORY LEUKOCYTE PROTEINASE INHIBITOR; SLPI PROTEIN, HUMAN;

ARTICLE; CONTROLLED STUDY; EPITHELIUM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; INFECTION SENSITIVITY; INFLUENZA VIRUS A; INNATE IMMUNITY; NONHUMAN; NOSE MUCOSA; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN SECRETION; VIRION; VIRUS ENTRY; VIRUS REPLICATION; ADULT; AIR POLLUTANT; BIOSYNTHESIS; CELL CULTURE; CHEMICALLY INDUCED DISORDER; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; INFLUENZA; METABOLISM; PATHOGENICITY; SECRETION;

ORTHOMYXOVIRIDAE;

ADULT; AIR POLLUTANTS; ANTIOXIDANTS; CELLS, CULTURED; HUMANS; INFLUENZA A VIRUS; INFLUENZA, HUMAN; NASAL MUCOSA; OZONE; PEPTIDE HYDROLASES; PROTEASE INHIBITORS; SECRETORY LEUKOCYTE PEPTIDASE INHIBITOR; VIRUS INTERNALIZATION; VIRUS REPLICATION;

EID: 84859508877     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0035108     Document Type: Article

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