-
1
-
-
77249117734
-
Potent inhibitors of furin and furin-like proprotein convertases containing decarboxylated P1 arginine mimetics
-
Becker, G. L., et al. 2010. Potent inhibitors of furin and furin-like proprotein convertases containing decarboxylated P1 arginine mimetics. J. Med. Chem. 53:1067-1075.
-
(2010)
J. Med. Chem.
, vol.53
, pp. 1067-1075
-
-
Becker, G.L.1
-
2
-
-
77956869264
-
TMPRSS2 and TMPRSS4 facilitate trypsin-independent influenza virus spread in Caco-2 cells
-
Bertram, S., et al. 2010. TMPRSS2 and TMPRSS4 facilitate trypsin-independent influenza virus spread in Caco-2 cells. J. Virol. 84:10016-10025.
-
(2010)
J. Virol.
, vol.84
, pp. 10016-10025
-
-
Bertram, S.1
-
3
-
-
0019513851
-
Proteolytic cleavage of influenza virus hemagglutinins: Primary structure of the connecting peptide between HA1 and HA2 determines proteolytic cleavability and pathogenicity of avian influenza viruses
-
Bosch, F. X., W. Garten, H. D. Klenk, and R. Rott. 1981. Proteolytic cleavage of influenza virus hemagglutinins: primary structure of the connecting peptide between HA1 and HA2 determines proteolytic cleavability and pathogenicity of avian influenza viruses. Virology 113:725-735.
-
(1981)
Virology
, vol.113
, pp. 725-735
-
-
Bosch, F.X.1
Garten, W.2
Klenk, H.D.3
Rott, R.4
-
4
-
-
68049130941
-
MDCK cells that express proteases TMPRSS2 and HAT provide a cell system to propagate influenza viruses in the absence of trypsin and to study cleavage of HA and its inhibition
-
Böttcher, E., C. Freuer, T. Steinmetzer, H. D. Klenk, and W. Garten. 2009. MDCK cells that express proteases TMPRSS2 and HAT provide a cell system to propagate influenza viruses in the absence of trypsin and to study cleavage of HA and its inhibition. Vaccine 27:6324-6329.
-
(2009)
Vaccine
, vol.27
, pp. 6324-6329
-
-
Böttcher, E.1
Freuer, C.2
Steinmetzer, T.3
Klenk, H.D.4
Garten, W.5
-
5
-
-
33748950305
-
Proteolytic activation of influenza viruses by serine proteases TMPRSS2 and HAT from human airway epithelium
-
DOI 10.1128/JVI.01118-06
-
Böttcher, E., et al. 2006. Proteolytic activation of influenza viruses by serine proteases TMPRSS2 and HAT from human airway epithelium. J. Virol. 80:9896-9898. (Pubitemid 44435664)
-
(2006)
Journal of Virology
, vol.80
, Issue.19
, pp. 9896-9898
-
-
Bottcher, E.1
Matrosovich, T.2
Beyerle, M.3
Klenk, H.-D.4
Garten, W.5
Matrosovich, M.6
-
6
-
-
77951983109
-
Cleavage of influenza virus hemagglutinin by airway proteases TMPRSS2 and HAT differs in subcellular localization and susceptibility to protease inhibitors
-
Böttcher-Friebertshäuser, E., et al. 2010. Cleavage of influenza virus hemagglutinin by airway proteases TMPRSS2 and HAT differs in subcellular localization and susceptibility to protease inhibitors. J. Virol. 84:5605-5614.
-
(2010)
J. Virol.
, vol.84
, pp. 5605-5614
-
-
Böttcher-Friebertshäuser, E.1
-
7
-
-
69949118724
-
Type II transmembrane serine proteases
-
Bugge, T. H., T. M. Antalis, and Q. Wu. 2009. Type II transmembrane serine proteases. J. Biol. Chem. 284:23177-23181.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 23177-23181
-
-
Bugge, T.H.1
Antalis, T.M.2
Wu, Q.3
-
8
-
-
63149086109
-
Proteolytic activation of the 1918 influenza virus hemagglutinin
-
Chaipan, C., et al. 2009. Proteolytic activation of the 1918 influenza virus hemagglutinin. J. Virol. 83:3200-3211.
-
(2009)
J. Virol.
, vol.83
, pp. 3200-3211
-
-
Chaipan, C.1
-
9
-
-
0037040995
-
Regulation of the epithelial sodium channel by serine proteases in human airways
-
Donaldson, S. H., et al. 2002. Regulation of the epithelial sodium channel by serine proteases in human airways. J. Biol. Chem. 277:8338-8345.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 8338-8345
-
-
Donaldson, S.H.1
-
10
-
-
49949086671
-
Controlling morpholino experiments: Don't stop making antisense
-
Eisen, J. S., and J. C. Smith. 2008. Controlling morpholino experiments: don't stop making antisense. Development 135:1735-1743.
-
(2008)
Development
, vol.135
, pp. 1735-1743
-
-
Eisen, J.S.1
Smith, J.C.2
-
11
-
-
0037458930
-
Drug transport and metabolism characteristics of the human airway epithelial cell line Calu-3
-
DOI 10.1016/S0168-3659(02)00356-5
-
Florea, B. I., M. L. Cassara, H. E. Junginger, and G. Borchard. 2003. Drug transport and metabolism characteristics of the human airway epithelial cell line Calu-3. J. Control Release 87:131-138. (Pubitemid 36255450)
-
(2003)
Journal of Controlled Release
, vol.87
, Issue.1-3
, pp. 131-138
-
-
Florea, B.I.1
Cassara, M.L.2
Junginger, H.E.3
Borchard, G.4
-
12
-
-
0033959120
-
Human airway epithelial cell lines for in vitro drug transport and metabolism studies
-
Forbes, B. 2000. Human airway epithelial cell lines for in vitro drug transport and metabolism studies. Pharm. Sci. Technol. Today 3:18-27.
-
(2000)
Pharm. Sci. Technol. Today
, vol.3
, pp. 18-27
-
-
Forbes, B.1
-
13
-
-
45549109283
-
Morpholino oligomers targeting the PB1 and NP genes enhance the survival of mice infected with highly pathogenic influenza A H7N7 virus
-
Gabriel, G., A. Nordmann, D. A. Stein, P. L. Iversen, and H. D. Klenk. 2008. Morpholino oligomers targeting the PB1 and NP genes enhance the survival of mice infected with highly pathogenic influenza A H7N7 virus. J. Gen. Virol. 89:939-948.
-
(2008)
J. Gen. Virol.
, vol.89
, pp. 939-948
-
-
Gabriel, G.1
Nordmann, A.2
Stein, D.A.3
Iversen, P.L.4
Klenk, H.D.5
-
14
-
-
50549096245
-
Cleavage activation of the influenza virus hemagglutinin and its role in pathogenesis
-
Avian influenza. Karger, Basel, Switzerland
-
Garten, W., and H. D. Klenk. 2008. Cleavage activation of the influenza virus hemagglutinin and its role in pathogenesis. Monographs in virology 27. Avian influenza. Karger, Basel, Switzerland.
-
(2008)
Monographs in Virology
, vol.27
-
-
Garten, W.1
Klenk, H.D.2
-
15
-
-
33750592240
-
Inhibition of multiple subtypes of influenza A virus in cell cultures with morpholino oligomers
-
Ge, Q., et al. 2006. Inhibition of multiple subtypes of influenza A virus in cell cultures with morpholino oligomers. Antimicrob. Agents Chemother. 50: 3724-3733.
-
(2006)
Antimicrob. Agents Chemother.
, vol.50
, pp. 3724-3733
-
-
Ge, Q.1
-
16
-
-
0033062736
-
Antisense morpholino oligonucleotide analog induces missplicing of C-myc mRNA
-
Giles, R. V., D. G. Spiller, R. E. Clark, and D. M. Tidd. 1999. Antisense morpholino oligonucleotide analog induces missplicing of C-myc mRNA. Antisense Nucleic Acid Drug Dev. 9:213-220.
-
(1999)
Antisense Nucleic Acid Drug Dev.
, vol.9
, pp. 213-220
-
-
Giles, R.V.1
Spiller, D.G.2
Clark, R.E.3
Tidd, D.M.4
-
17
-
-
38449107595
-
TMPRSS3, a type II transmembrane serine protease mutated in non-syndromic autosomal recessive deafness
-
Guipponi, M., S. E. Antonarakis, and H. S. Scott. 2008. TMPRSS3, a type II transmembrane serine protease mutated in non-syndromic autosomal recessive deafness. Front. Biosci. 13:1557-1567.
-
(2008)
Front. Biosci.
, vol.13
, pp. 1557-1567
-
-
Guipponi, M.1
Antonarakis, S.E.2
Scott, H.S.3
-
18
-
-
0028095251
-
Proprotein-processing endoproteases PC6 and furin both activate hemagglutinin of virulent avian influenza viruses
-
Horimoto, T., K. Nakayama, S. P. Smeekens, and Y. Kawaoka. 1994. Proprotein- processing endoproteases PC6 and furin both activate hemagglutinin of virulent avian influenza viruses. J. Virol. 68:6074-6078. (Pubitemid 24258628)
-
(1994)
Journal of Virology
, vol.68
, Issue.9
, pp. 6074-6078
-
-
Horimoto, T.1
Nakayama, K.2
Smeekens, S.P.3
Kawaoka, Y.4
-
19
-
-
0030475053
-
Resistance of morpholino phosphorodiamidate oligomers to enzymatic degradation
-
Hudziak, R. M., et al. 1996. Resistance of morpholino phosphorodiamidate oligomers to enzymatic degradation. Antisense Nucleic Acid Drug Dev. 6:267-272.
-
(1996)
Antisense Nucleic Acid Drug Dev.
, vol.6
, pp. 267-272
-
-
Hudziak, R.M.1
-
20
-
-
0034850380
-
Cloning and characterization of the cDNA and gene for human epitheliasin
-
Jacquinet, E., et al. 2001. Cloning and characterization of the cDNA and gene for human epitheliasin. Eur. J. Biochem. 268:2687-2699.
-
(2001)
Eur. J. Biochem.
, vol.268
, pp. 2687-2699
-
-
Jacquinet, E.1
-
21
-
-
31344447481
-
Phenotypic analysis of mice lacking the Tmprss2-encoded protease
-
Kim, T. S., C. Heinlein, R. C. Hackman, and P. S. Nelson. 2006. Phenotypic analysis of mice lacking the Tmprss2-encoded protease. Mol. Cell. Biol. 26:965-975.
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 965-975
-
-
Kim, T.S.1
Heinlein, C.2
Hackman, R.C.3
Nelson, P.S.4
-
22
-
-
0028123337
-
Host cell proteases controlling virus pathogenicity
-
Klenk, H. D., and W. Garten. 1994. Host cell proteases controlling virus pathogenicity. Trends Microbiol. 2:39-43.
-
(1994)
Trends Microbiol.
, vol.2
, pp. 39-43
-
-
Klenk, H.D.1
Garten, W.2
-
23
-
-
0016679968
-
Activation of influenza A viruses by trypsin treatment
-
Klenk, H. D., R. Rott, M. Orlich, and J. Blödorn. 1975. Activation of influenza A viruses by trypsin treatment. Virology 68:426-439.
-
(1975)
Virology
, vol.68
, pp. 426-439
-
-
Klenk, H.D.1
Rott, R.2
Orlich, M.3
Blödorn, J.4
-
24
-
-
60049100922
-
Severe acute respiratory syndrome coronavirus triggers apoptosis via protein kinase R but is resistant to its antiviral activity
-
Krähling, V., D. A. Stein, M. Spiegel, F. Weber, and E. Mühlberger. 2009. Severe acute respiratory syndrome coronavirus triggers apoptosis via protein kinase R but is resistant to its antiviral activity. J. Virol. 83:2298-2309.
-
(2009)
J. Virol.
, vol.83
, pp. 2298-2309
-
-
Krähling, V.1
Stein, D.A.2
Spiegel, M.3
Weber, F.4
Mühlberger, E.5
-
25
-
-
38949206876
-
Cell penetrating peptide conjugates of steric block oligonucleotides
-
Lebleu, B., et al. 2008. Cell penetrating peptide conjugates of steric block oligonucleotides. Adv. Drug Deliv. Rev. 60:517-529.
-
(2008)
Adv. Drug Deliv. Rev.
, vol.60
, pp. 517-529
-
-
Lebleu, B.1
-
26
-
-
42449149049
-
Inhibition of influenza A H3N8 virus infections in mice by morpholino oligomers
-
Lupfer, C., et al. 2008. Inhibition of influenza A H3N8 virus infections in mice by morpholino oligomers. Arch. Virol. 153:929-937.
-
(2008)
Arch. Virol.
, vol.153
, pp. 929-937
-
-
Lupfer, C.1
-
27
-
-
33748682298
-
New low-viscosity overlay medium for viral plaque assays
-
Matrosovich, M., T. Matrosovich, W. Garten, and H. D. Klenk. 2006. New low-viscosity overlay medium for viral plaque assays. Virol. J. 3:63.
-
(2006)
Virol. J.
, vol.3
, pp. 63
-
-
Matrosovich, M.1
Matrosovich, T.2
Garten, W.3
Klenk, H.D.4
-
28
-
-
70349449584
-
Inhibition of HSV-1 ocular infection with morpholino oligomers targeting ICP0 and ICP27
-
Moerdyk-Schauwecker, M., et al. 2009. Inhibition of HSV-1 ocular infection with morpholino oligomers targeting ICP0 and ICP27. Antiviral Res. 84: 131-141.
-
(2009)
Antiviral Res.
, vol.84
, pp. 131-141
-
-
Moerdyk-Schauwecker, M.1
-
29
-
-
77958152873
-
Morpholinos and their peptide conjugates: Therapeutic promise and challenge for Duchenne muscular dystrophy
-
Moulton, H. M., and J. D. Moulton. 2010. Morpholinos and their peptide conjugates: therapeutic promise and challenge for Duchenne muscular dystrophy. Biochim. Biophys. Acta 1798:2296-2303.
-
(2010)
Biochim. Biophys. Acta
, vol.1798
, pp. 2296-2303
-
-
Moulton, H.M.1
Moulton, J.D.2
-
30
-
-
1642321105
-
Cellular uptake of antisense morpholino oligomers conjugated to arginine-rich peptides
-
Moulton, H. M., M. H. Nelson, S. A. Hatlevig, M. T. Reddy, and P. L. Iversen. 2004. Cellular uptake of antisense morpholino oligomers conjugated to arginine-rich peptides. Bioconjug. Chem. 15:290-299.
-
(2004)
Bioconjug. Chem.
, vol.15
, pp. 290-299
-
-
Moulton, H.M.1
Nelson, M.H.2
Hatlevig, S.A.3
Reddy, M.T.4
Iversen, P.L.5
-
31
-
-
77951433024
-
Novel type II transmembrane serine proteases, MSPL and TMPRSS13, proteolytically activate membrane fusion activity of the hemagglutinin of highly pathogenic avian influenza viruses and induce their multicycle replication
-
Okumura, Y., et al. 2010. Novel type II transmembrane serine proteases, MSPL and TMPRSS13, proteolytically activate membrane fusion activity of the hemagglutinin of highly pathogenic avian influenza viruses and induce their multicycle replication. J. Virol. 84:5089-5096.
-
(2010)
J. Virol.
, vol.84
, pp. 5089-5096
-
-
Okumura, Y.1
-
32
-
-
0031572305
-
Cloning of the TMPRSS2 gene, which encodes a novel serine protease with transmembrane, LDLRA, and SRCR domains and maps to 21q22.3
-
Erratum, 77:114, 2001
-
Paoloni-Giacobino, A., H. Chen, M. C. Peitsch, C. Rossier, and S. E. Antonarakis. 1997. Cloning of the TMPRSS2 gene, which encodes a novel serine protease with transmembrane, LDLRA, and SRCR domains and maps to 21q22.3. Genomics 44:309-320. (Erratum, 77:114, 2001.)
-
(1997)
Genomics
, vol.44
, pp. 309-320
-
-
Paoloni-Giacobino, A.1
Chen, H.2
Peitsch, M.C.3
Rossier, C.4
Antonarakis, S.E.5
-
33
-
-
67049134745
-
Molecular mechanisms of the defective hepcidin inhibition in TMPRSS6 mutations associated with iron-refractory iron defi- ciency anemia
-
Silvestri, L., et al. 2009. Molecular mechanisms of the defective hepcidin inhibition in TMPRSS6 mutations associated with iron-refractory iron defi- ciency anemia. Blood 113:5605-5608.
-
(2009)
Blood
, vol.113
, pp. 5605-5608
-
-
Silvestri, L.1
-
34
-
-
0033783032
-
Receptor binding and membrane fusion in virus entry: The influenza hemagglutinin
-
Skehel, J. J., and D. C. Wiley. 2000. Receptor binding and membrane fusion in virus entry: the influenza hemagglutinin. Annu. Rev. Biochem. 69:531-569.
-
(2000)
Annu. Rev. Biochem.
, vol.69
, pp. 531-569
-
-
Skehel, J.J.1
Wiley, D.C.2
-
35
-
-
57349187597
-
Inhibition of RNA virus infections with peptide-conjugated morpholino oligomers
-
Stein, D. A. 2008. Inhibition of RNA virus infections with peptide-conjugated morpholino oligomers. Curr. Pharm. Des. 14:2619-2634.
-
(2008)
Curr. Pharm. Des.
, vol.14
, pp. 2619-2634
-
-
Stein, D.A.1
-
36
-
-
0030747101
-
A specificity comparison of four antisense types: Morpholino, 2'-O-methyl RNA, DNA, and phosphorothioate DNA
-
Stein, D., E. Foster, S. B. Huang, D. Weller, and J. Summerton. 1997. A specificity comparison of four antisense types: morpholino, 2′-O-methyl RNA, DNA, and phosphorothioate DNA. Antisense Nucleic Acid Drug Dev. 7:151-157. (Pubitemid 27323073)
-
(1997)
Antisense and Nucleic Acid Drug Development
, vol.7
, Issue.3
, pp. 151-157
-
-
Stein, D.1
Foster, E.2
Huang, S.-B.3
Weller, D.4
Summerton, J.5
-
37
-
-
0033602713
-
Role of hemagglutinin cleavage for the pathogenicity of influenza virus
-
DOI 10.1006/viro.1999.9716
-
Steinhauer, D. A. 1999. Role of hemagglutinin cleavage for the pathogenicity of influenza virus. Virology 258:1-20. (Pubitemid 29391776)
-
(1999)
Virology
, vol.258
, Issue.1
, pp. 1-20
-
-
Steinhauer, D.A.1
-
38
-
-
0026643396
-
Influenza virus hemagglutinin with multibasic cleavage site is activated by furin, a subtilisin-like endoprotease
-
Stieneke-Grõber, A., et al. 1992. Influenza virus hemagglutinin with multibasic cleavage site is activated by furin, a subtilisin-like endoprotease. EMBO J. 11:2407-2414.
-
(1992)
EMBO J.
, vol.11
, pp. 2407-2414
-
-
Stieneke-Grõber, A.1
-
39
-
-
0032699477
-
Morpholino antisense oligomers: The case for an RNase H-independent structural type
-
Summerton, J. 1999. Morpholino antisense oligomers: the case for an RNase H-independent structural type. Biochim. Biophys. Acta 1489:141-158.
-
(1999)
Biochim. Biophys. Acta
, vol.1489
, pp. 141-158
-
-
Summerton, J.1
-
40
-
-
0030862707
-
Morpholino antisense oligomers: Design, preparation, and properties
-
Summerton, J., and D. Weller. 1997. Morpholino antisense oligomers: design, preparation, and properties. Antisense Nucleic Acid Drug Dev. 7:187-195. (Pubitemid 27323077)
-
(1997)
Antisense and Nucleic Acid Drug Development
, vol.7
, Issue.3
, pp. 187-195
-
-
Summerton, J.1
Weller, D.2
-
41
-
-
0035087724
-
Localization of human airway trypsin-like protease in the airway: An immunohistochemical study
-
Takahashi, M., et al. 2001. Localization of human airway trypsin-like protease in the airway: an immunohistochemical study. Histochem. Cell Biol. 115:181-187.
-
(2001)
Histochem. Cell Biol.
, vol.115
, pp. 181-187
-
-
Takahashi, M.1
-
42
-
-
0035164352
-
Expression of transmembrane serine protease TMPRSS2 in mouse and human tissues
-
Vaarala, M. H., K. S. Porvari, S. Kellokumpu, A. P. Kyllönen, and P. T. Vihko. 2001. Expression of transmembrane serine protease TMPRSS2 in mouse and human tissues. J. Pathol. 193:134-140.
-
(2001)
J. Pathol.
, vol.193
, pp. 134-140
-
-
Vaarala, M.H.1
Porvari, K.S.2
Kellokumpu, S.3
Kyllönen, A.P.4
Vihko, P.T.5
-
43
-
-
0026748702
-
Hemagglutinin activation of pathogenic avian influenza viruses of serotype H7 requires the protease recognition motif R-X-K/R-R
-
Vey, M., et al. 1992. Hemagglutinin activation of pathogenic avian influenza viruses of serotype H7 requires the protease recognition motif R-X-K/R-R. Virology 188:408-413.
-
(1992)
Virology
, vol.188
, pp. 408-413
-
-
Vey, M.1
-
44
-
-
36048957993
-
Highly pathogenic avian influenza H5N1 viruses elicit an attenuated type I interferon response in polarized human bronchial epithelial cells
-
Zeng, H., et al. 2007. Highly pathogenic avian influenza H5N1 viruses elicit an attenuated type I interferon response in polarized human bronchial epithelial cells. J. Virol. 81:12439-12449.
-
(2007)
J. Virol.
, vol.81
, pp. 12439-12449
-
-
Zeng, H.1
-
45
-
-
0036337409
-
Cleavage of influenza A virus hemagglutinin in human respiratory epithelium is cell associated and sensitive to exogenous antiproteases
-
Zhirnov, O. P., M. R. Ikizler, and P. F. Wright. 2002. Cleavage of influenza A virus hemagglutinin in human respiratory epithelium is cell associated and sensitive to exogenous antiproteases. J. Virol. 76:8682-8689.
-
(2002)
J. Virol.
, vol.76
, pp. 8682-8689
-
-
Zhirnov, O.P.1
Ikizler, M.R.2
Wright, P.F.3
-
46
-
-
34548569135
-
Cell-penetrating peptides as transporters for morpholino oligomers: Effects of amino acid composition on intracellular delivery and cytotoxicity
-
Wu, R. P., et al. 2007. Cell-penetrating peptides as transporters for morpholino oligomers: effects of amino acid composition on intracellular delivery and cytotoxicity. Nucleic Acids Res. 35:5182-5191.
-
(2007)
Nucleic Acids Res.
, vol.35
, pp. 5182-5191
-
-
Wu, R.P.1
|