5-Hydroxytryptamine 5HT2C receptors form a protein complex with N-methyl-D-aspartate GluN2A subunits and activate phosphorylation of Src protein to modulate motoneuronal depolarization

Journal of Biological Chemistry

Volumn 287, Issue 14, 2012, Pages 11049-11059

  Bigford, Gregory E ^a,b   Chaudhry, Nauman S ^a   Keane, Robert W ^a,b   Holohean, Alice M ^a,b  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AFTER-TREATMENT; CO-IMMUNOPRECIPITATIONS; DOSE-DEPENDENT MANNER; FUNCTIONAL ACTIVITIES; IMMUNOHISTOCHEMICAL ANALYSIS; INTRACELLULAR SIGNALING; ION CHANNEL; ISOFORMS; MOLECULAR MECHANISM; MULTI-PROTEIN COMPLEX; N-METHYL-D-ASPARTATE; PROTEIN ASSOCIATIONS; PROTEIN COMPLEXES; RT-PCR ANALYSIS; SPINAL CORDS; TYROSINE KINASE; TYROSINE KINASE INHIBITOR;

AMINO ACIDS; DEPOLARIZATION; DOSIMETRY; ENZYMES; MAMMALS; PHOSPHORYLATION; PROTEINS;

NEURONS;

6 CHLORO 2 (1 PIPERAZINYL)PYRAZINE; CALCIUM ION; G PROTEIN COUPLED RECEPTOR; N METHYL DEXTRO ASPARTIC ACID; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE INHIBITOR; SEROTONIN 2C ANTAGONIST; SEROTONIN 2C RECEPTOR; TYROSINE;

5 HYDROXYTRYPTAMINE 2C RECEPTOR GENE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; FEMALE; IMMUNOCYTOCHEMISTRY; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; INTRACELLULAR SIGNALING; MALE; NERVE CELL MEMBRANE POTENTIAL; NERVE CELL MEMBRANE STEADY POTENTIAL; NEUROMODULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; RAT; RECEPTOR GENE; SPINAL CORD MOTONEURON; SYNAPTIC MEMBRANE; UPREGULATION;

ANIMALS; BASE SEQUENCE; ENZYME ACTIVATION; MALE; MEMBRANE POTENTIALS; MOTOR NEURONS; N-METHYLASPARTATE; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN TRANSPORT; RANA PIPIENS; RATS; RECEPTOR, SEROTONIN, 5-HT2C; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, N-METHYL-D-ASPARTATE; SPINAL CORD; SRC-FAMILY KINASES; SYNAPTOSOMES;

MAMMALIA;

EID: 84859479201     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.277806     Document Type: Article

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