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Volumn 94, Issue 4, 2005, Pages 2867-2877

Serotonin 5-HT2 receptors induce a long-lasting facilitation of spinal reflexes independent of ionotropic receptor activity

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINO 5 PHOSPHONOVALERIC ACID; 2 DIPROPYLAMINO 8 HYDROXYTETRALIN; 4 AMINOBUTYRIC ACID A RECEPTOR; 4 IODO 2,5 DIMETHOXYAMPHETAMINE; 6 CHLORO 2 (1 PIPERAZINYL)PYRAZINE; 6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; AMPA RECEPTOR; AMPA RECEPTOR ANTAGONIST; BICUCULLINE METHIODIDE; CLOZAPINE; GLYCINE RECEPTOR; KAINIC ACID RECEPTOR; KYNURENIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; SEROTONIN; SEROTONIN 2 RECEPTOR; SEROTONIN 2A RECEPTOR; SEROTONIN 2C AGONIST; SEROTONIN 2C RECEPTOR; 4-IODO-2,5-DIMETHOXYPHENYLISOPROPYLAMINE; AMPHETAMINE DERIVATIVE; PYRAZINE DERIVATIVE; SEROTONIN AGONIST; SEROTONIN ANTAGONIST;

EID: 24944565879     PISSN: 00223077     EISSN: None     Source Type: Journal    
DOI: 10.1152/jn.00465.2005     Document Type: Article
Times cited : (30)

References (63)
  • 1
    • 0037101635 scopus 로고    scopus 로고
    • Phrenic long-term facilitation requires spinal serotonin receptor activation and protein synthesis
    • Baker-Herman TL and Mitchell GS. Phrenic long-term facilitation requires spinal serotonin receptor activation and protein synthesis. J Neurosci 22: 6239-6246, 2002.
    • (2002) J Neurosci , vol.22 , pp. 6239-6246
    • Baker-Herman, T.L.1    Mitchell, G.S.2
  • 3
    • 0031739279 scopus 로고    scopus 로고
    • Synaptic activation of plateaus in hindlimb motoneurons of decerebrate cats
    • Bennett DJ, Hultborn H, Fedirchuk B, and Gorassini M. Synaptic activation of plateaus in hindlimb motoneurons of decerebrate cats. J Neurophysiol 80: 2023-2037, 1998.
    • (1998) J Neurophysiol , vol.80 , pp. 2023-2037
    • Bennett, D.J.1    Hultborn, H.2    Fedirchuk, B.3    Gorassini, M.4
  • 4
    • 0031815337 scopus 로고    scopus 로고
    • Effector pathway-dependent relative efficacy at serotonin type 2A and 2C receptors: Evidence for agonist-directed trafficking of receptor stimulus
    • Berg KA, Maayani S, Goldfarb J, Scaramellini C, Leff P, and Clarke WP. Effector pathway-dependent relative efficacy at serotonin type 2A and 2C receptors: evidence for agonist-directed trafficking of receptor stimulus. Mol Pharmacol 54: 94-104, 1998.
    • (1998) Mol Pharmacol , vol.54 , pp. 94-104
    • Berg, K.A.1    Maayani, S.2    Goldfarb, J.3    Scaramellini, C.4    Leff, P.5    Clarke, W.P.6
  • 5
    • 0025441358 scopus 로고
    • Serotonin enhances a low-voltage-activated calcium current in rat spinal motoneurons
    • Berger AJ and Takahashi T. Serotonin enhances a low-voltage-activated calcium current in rat spinal motoneurons. J Neurosci 10: 1922-1928, 1990.
    • (1990) J Neurosci , vol.10 , pp. 1922-1928
    • Berger, A.J.1    Takahashi, T.2
  • 6
    • 0029657987 scopus 로고    scopus 로고
    • 2 receptor activation potentiates N-methyl-D-aspartate receptor-mediated ion currents by a protein kinase C-dependent mechanism
    • 2 receptor activation potentiates N-methyl-D-aspartate receptor-mediated ion currents by a protein kinase C-dependent mechanism. J Neurosci Res 45: 153-160, 1996.
    • (1996) J Neurosci Res , vol.45 , pp. 153-160
    • Blank, T.1    Zwart, R.2    Nijholt, I.3    Spiess, J.4
  • 7
    • 1642447131 scopus 로고    scopus 로고
    • Synaptic activity-independent persistent plasticity in endogenously active mammalian motoneurons
    • Bocchiaro CM and Feldman JL. Synaptic activity-independent persistent plasticity in endogenously active mammalian motoneurons. Proc Natl Acad Sci USA 101: 4292-4295, 2004.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 4292-4295
    • Bocchiaro, C.M.1    Feldman, J.L.2
  • 8
    • 0242472014 scopus 로고    scopus 로고
    • Dendritic L-type calcium currents in mouse spinal motoneurons: Implications for bistability
    • Carlin KP, Jones KE, Jiang Z, Jordan LM, and Brownstone RM. Dendritic L-type calcium currents in mouse spinal motoneurons: implications for bistability. Eur J Neurosci 12: 1635-1646, 2000.
    • (2000) Eur J Neurosci , vol.12 , pp. 1635-1646
    • Carlin, K.P.1    Jones, K.E.2    Jiang, Z.3    Jordan, L.M.4    Brownstone, R.M.5
  • 9
    • 0027477465 scopus 로고
    • Contribution of central neuroplasticity to pathological pain: Review of clinical and experimental evidence
    • Coderre TJ, Katz J, Vaccarino AL, and Melzack R. Contribution of central neuroplasticity to pathological pain: review of clinical and experimental evidence. Pain 52: 259-285, 1993.
    • (1993) Pain , vol.52 , pp. 259-285
    • Coderre, T.J.1    Katz, J.2    Vaccarino, A.L.3    Melzack, R.4
  • 10
    • 0029089238 scopus 로고
    • Effects of inhibitory amino acid antagonists on reciprocal inhibitory interactions during rhythmic motor activity in the in vitro neonatal rat spinal cord
    • Cowley KC and Schmidt BJ. Effects of inhibitory amino acid antagonists on reciprocal inhibitory interactions during rhythmic motor activity in the in vitro neonatal rat spinal cord. J Neurophysiol 74: 1109-1117, 1995.
    • (1995) J Neurophysiol , vol.74 , pp. 1109-1117
    • Cowley, K.C.1    Schmidt, B.J.2
  • 11
    • 0025897001 scopus 로고
    • Inhibition of reflex responses of neonate rat lumbar spinal cord by5-hydroxytryptamine
    • Crick H and Wallis DI. Inhibition of reflex responses of neonate rat lumbar spinal cord by5-hydroxytryptamine. Br J Pharmacol 103: 1769-1775, 1991.
    • (1991) Br J Pharmacol , vol.103 , pp. 1769-1775
    • Crick, H.1    Wallis, D.I.2
  • 12
    • 0007430781 scopus 로고
    • An electrically isolated stimulator for neurophysiological research
    • Eide E. An electrically isolated stimulator for neurophysiological research. Acta Physiol Scand (Abstract). 84: 3, 1972.
    • (1972) Acta Physiol Scand (Abstract) , vol.84 , pp. 3
    • Eide, E.1
  • 13
    • 0027534709 scopus 로고
    • The role of 5-hydroxytryptamine (5-HT) receptor subtypes and plasticity in the 5-HT systems in the regulation of nociceptive sensitivity
    • Eide PK and Hole K. The role of 5-hydroxytryptamine (5-HT) receptor subtypes and plasticity in the 5-HT systems in the regulation of nociceptive sensitivity. Cephalalgia 13: 75-85, 1993.
    • (1993) Cephalalgia , vol.13 , pp. 75-85
    • Eide, P.K.1    Hole, K.2
  • 14
    • 0026560795 scopus 로고
    • Serotonin and L-norepinephrine as mediators of altered excitability in neonatal rat motoneurons studied in vitro
    • Elliott P and Wallis DI. Serotonin and L-norepinephrine as mediators of altered excitability in neonatal rat motoneurons studied in vitro. Neuroscience 47: 533-544, 1992.
    • (1992) Neuroscience , vol.47 , pp. 533-544
    • Elliott, P.1    Wallis, D.I.2
  • 15
    • 0032932716 scopus 로고    scopus 로고
    • Ionic mechanisms underlying excitatory effects of serotonin on embryonic rat motoneurons in long-term culture
    • Elliott P, Wallis DI, Foster GA, and Stringer BMJ. Ionic mechanisms underlying excitatory effects of serotonin on embryonic rat motoneurons in long-term culture. Neuroscience 90: 1311-1323, 1999.
    • (1999) Neuroscience , vol.90 , pp. 1311-1323
    • Elliott, P.1    Wallis, D.I.2    Foster, G.A.3    Stringer, B.M.J.4
  • 16
    • 0024444867 scopus 로고
    • The pharmacology of segmental transmission in the spinal cord
    • Evans RH. The pharmacology of segmental transmission in the spinal cord. Prog Neurobiol 33: 255-279, 1989.
    • (1989) Prog Neurobiol , vol.33 , pp. 255-279
    • Evans, R.H.1
  • 17
    • 13844270921 scopus 로고    scopus 로고
    • Development of circuits that generate simple rhythmic behaviors in vertebrates
    • Goulding M and Pfaff SL. Development of circuits that generate simple rhythmic behaviors in vertebrates. Curr Opin Neurobiol 15: 14-20, 2005.
    • (2005) Curr Opin Neurobiol , vol.15 , pp. 14-20
    • Goulding, M.1    Pfaff, S.L.2
  • 18
    • 0021364017 scopus 로고
    • The edge cell, a possible intraspinal mechanoreceptor
    • Grillner S, Williams T, and Lagerback PA. The edge cell, a possible intraspinal mechanoreceptor. Science 223: 500-503, 1984.
    • (1984) Science , vol.223 , pp. 500-503
    • Grillner, S.1    Williams, T.2    Lagerback, P.A.3
  • 19
    • 0033039831 scopus 로고    scopus 로고
    • Differences in agonist-independent activity of 5-Ht2A and 5-HT2c receptors revealed by heterologous expression
    • Grotewiel MS and Sanders-Bush E. Differences in agonist-independent activity of 5-Ht2A and 5-HT2c receptors revealed by heterologous expression. Naunyn-Schmiedebergs Arch Pharmacol 359: 21-27, 1999.
    • (1999) Naunyn-Schmiedebergs Arch Pharmacol , vol.359 , pp. 21-27
    • Grotewiel, M.S.1    Sanders-Bush, E.2
  • 20
    • 0037032542 scopus 로고    scopus 로고
    • Role of serotonin 1A receptors on the modulation of rat spinal mono-synaptic reflexes in vitro
    • Hedo G, Ajubita M, and Lopez-Garcia JA. Role of serotonin 1A receptors on the modulation of rat spinal mono-synaptic reflexes in vitro. Neurosci Lett 334: 41-44, 2002.
    • (2002) Neurosci Lett , vol.334 , pp. 41-44
    • Hedo, G.1    Ajubita, M.2    Lopez-Garcia, J.A.3
  • 21
    • 0032999084 scopus 로고    scopus 로고
    • Time-course of spinal sensitization following carrageenan-induced inflammation in the young rat: A comparative electrophysiological and behavioural study in vitro and in vivo
    • Hedo G, Laird JM, and Lopez-Garcia JA. Time-course of spinal sensitization following carrageenan-induced inflammation in the young rat: a comparative electrophysiological and behavioural study in vitro and in vivo. Neuroscience 92: 309-318, 1999.
    • (1999) Neuroscience , vol.92 , pp. 309-318
    • Hedo, G.1    Laird, J.M.2    Lopez-Garcia, J.A.3
  • 22
    • 0036184894 scopus 로고    scopus 로고
    • 5-HT(1B) but not 5-HT(6) or 5-HT(7) receptors mediate depression of spinal nociceptive reflexes in vitro
    • Hedo G and Lopez-Garcia JA. 5-HT(1B) but not 5-HT(6) or 5-HT(7) receptors mediate depression of spinal nociceptive reflexes in vitro. Br J Pharmacol 135: 935-942, 2002.
    • (2002) Br J Pharmacol , vol.135 , pp. 935-942
    • Hedo, G.1    Lopez-Garcia, J.A.2
  • 24
    • 0032525185 scopus 로고    scopus 로고
    • + channels in dendrites of hippocampal CA1 pyramidal neurons by activation of PKA and PKC
    • + channels in dendrites of hippocampal CA1 pyramidal neurons by activation of PKA and PKC. J Neurosci 18: 3521-3528, 1998.
    • (1998) J Neurosci , vol.18 , pp. 3521-3528
    • Hoffman, D.A.1    Johnston, D.2
  • 25
    • 0025240822 scopus 로고
    • Changes in membrane potential of frog motoneurons induced by activation of serotonin receptor subtypes
    • Holohean AM, Hackman JC, and Davidoff RA. Changes in membrane potential of frog motoneurons induced by activation of serotonin receptor subtypes. Neuroscience 34: 555-564. 1990.
    • (1990) Neuroscience , vol.34 , pp. 555-564
    • Holohean, A.M.1    Hackman, J.C.2    Davidoff, R.A.3
  • 26
    • 0029929076 scopus 로고    scopus 로고
    • Long-lasting synaptic facilitation induced by serotonin in superficial dorsal horn neurones of the rat spinal cord
    • Hori Y, Endo K, and Takahashi T. Long-lasting synaptic facilitation induced by serotonin in superficial dorsal horn neurones of the rat spinal cord. J Physiol 492: 867-876, 1996.
    • (1996) J Physiol , vol.492 , pp. 867-876
    • Hori, Y.1    Endo, K.2    Takahashi, T.3
  • 27
    • 0032975514 scopus 로고    scopus 로고
    • Actions of 3-[2′-phosphonomethyl]1,1′-biphenyl-3-ylalanine (PMBA) on cloned glycine receptors
    • Hosie AM, Akagi H, Ishida M, and Shinozaki H. Actions of 3-[2′-phosphonomethyl]1,1′-biphenyl]-3-yl]alanine (PMBA) on cloned glycine receptors. Br J Pharmacol 126: 1230-1236, 1999.
    • (1999) Br J Pharmacol , vol.126 , pp. 1230-1236
    • Hosie, A.M.1    Akagi, H.2    Ishida, M.3    Shinozaki, H.4
  • 28
    • 0025143974 scopus 로고
    • Receptor subtypes mediating facilitation by serotonin of excitability of spinal motoneurons
    • Jackson DA and White SR. Receptor subtypes mediating facilitation by serotonin of excitability of spinal motoneurons. Neuropharmacology 29: 787-797, 1990.
    • (1990) Neuropharmacology , vol.29 , pp. 787-797
    • Jackson, D.A.1    White, S.R.2
  • 29
    • 0027250812 scopus 로고
    • 5-HT and motor control: A hypothesis
    • Jacobs BL and Fornal CA. 5-HT and motor control: a hypothesis. Trends Neurosci 16: 346-352. 1993.
    • (1993) Trends Neurosci , vol.16 , pp. 346-352
    • Jacobs, B.L.1    Fornal, C.A.2
  • 30
    • 0026578897 scopus 로고
    • Interneuronal relay in spinal pathways from proprioceptors
    • Jankowska E. Interneuronal relay in spinal pathways from proprioceptors. Prog Neurobiol 38: 335-378. 1992.
    • (1992) Prog Neurobiol , vol.38 , pp. 335-378
    • Jankowska, E.1
  • 31
    • 0035867016 scopus 로고    scopus 로고
    • Spinal interneuronal systems: Identification, multifunctional character and reconfigurations in mammals
    • Jankowska E. Spinal interneuronal systems: identification, multifunctional character and reconfigurations in mammals. J Physiol 533: 31-40, 2001.
    • (2001) J Physiol , vol.533 , pp. 31-40
    • Jankowska, E.1
  • 33
    • 0026756860 scopus 로고
    • Antagonism of synaptic potentials in ventral horn neurones by 6-cyano-7-nitroquinoxaline-2,3-di-one: A study in the rat spinal cord m vitro
    • King AE, Lopez-Garcia JA, and Cumberbatch M. Antagonism of synaptic potentials in ventral horn neurones by 6-cyano-7-nitroquinoxaline-2,3-di-one: a study in the rat spinal cord m vitro. Br J Pharmacol 107: 375-381, 1992.
    • (1992) Br J Pharmacol , vol.107 , pp. 375-381
    • King, A.E.1    Lopez-Garcia, J.A.2    Cumberbatch, M.3
  • 34
    • 0030910637 scopus 로고    scopus 로고
    • Localization of the spinal network associated with generation of hindlimb locomotion in the neonatal rat and organization of its transverse coupling system
    • Kremer E and Lev-Tov A. Localization of the spinal network associated with generation of hindlimb locomotion in the neonatal rat and organization of its transverse coupling system. J Neurophysiol 77: 1155-1170, 1997.
    • (1997) J Neurophysiol , vol.77 , pp. 1155-1170
    • Kremer, E.1    Lev-Tov, A.2
  • 35
    • 0016781144 scopus 로고
    • The effect of strychnine on membrane properties of spinal motoneurons in the cat
    • Lee KC, Klee MR, and Lee HJ. The effect of strychnine on membrane properties of spinal motoneurons in the cat. Yonsei Med J 16: 1-28, 1975.
    • (1975) Yonsei Med J , vol.16 , pp. 1-28
    • Lee, K.C.1    Klee, M.R.2    Lee, H.J.3
  • 36
    • 0031813246 scopus 로고    scopus 로고
    • Bistability in spinal motoneurons in vivo: Systematic variations in persistent inward currents
    • Lee RH and Heckman CJ. Bistability in spinal motoneurons in vivo: systematic variations in persistent inward currents. J Neurophysiol 80: 583-593, 1998.
    • (1998) J Neurophysiol , vol.80 , pp. 583-593
    • Lee, R.H.1    Heckman, C.J.2
  • 37
    • 0027278787 scopus 로고
    • The actions of 5-hydroxytryptamine on the membrane of putative sympatho-excitatory neurones in the rostral ventrolateral medulla of the adult rat in vitro
    • Lewis DI and Coote JH. The actions of 5-hydroxytryptamine on the membrane of putative sympatho-excitatory neurones in the rostral ventrolateral medulla of the adult rat in vitro. Brain Res 609: 103-109, 1993.
    • (1993) Brain Res , vol.609 , pp. 103-109
    • Lewis, D.I.1    Coote, J.H.2
  • 38
    • 0027210715 scopus 로고
    • Excitatory and indirect inhibitory actions of 5-hydroxytryptamine on sympathetic preganglionic neurones in the neonate rat spinal cord in vitro
    • Lewis DI, Sermasi E, and Coote JH. Excitatory and indirect inhibitory actions of 5-hydroxytryptamine on sympathetic preganglionic neurones in the neonate rat spinal cord in vitro. Brain Res 610: 267-275, 1993.
    • (1993) Brain Res , vol.610 , pp. 267-275
    • Lewis, D.I.1    Sermasi, E.2    Coote, J.H.3
  • 40
    • 0033552931 scopus 로고    scopus 로고
    • Kainate-receptor-mediated sensory synaptic transmission in mammalian spinal cord
    • Li P, Wilding TJ, Kim SJ, Calejesan AA, Huettner JE, and Zhuo M. Kainate-receptor-mediated sensory synaptic transmission in mammalian spinal cord. Nature 397: 161-164, 1999.
    • (1999) Nature , vol.397 , pp. 161-164
    • Li, P.1    Wilding, T.J.2    Kim, S.J.3    Calejesan, A.A.4    Huettner, J.E.5    Zhuo, M.6
  • 41
    • 0032543576 scopus 로고    scopus 로고
    • Silent glutamatergic synapses and nociception in mammalian spinal cord
    • Li P and Zhuo M. Silent glutamatergic synapses and nociception in mammalian spinal cord. Nature 393: 695-698, 1998.
    • (1998) Nature , vol.393 , pp. 695-698
    • Li, P.1    Zhuo, M.2
  • 42
    • 0141646406 scopus 로고    scopus 로고
    • A specific inhibitory pathway between substantia gelatinosa neurons receiving direct C-fiber input
    • Lu Y and Perl ER. A specific inhibitory pathway between substantia gelatinosa neurons receiving direct C-fiber input. J Neurosci 23: 8752-8758, 2003.
    • (2003) J Neurosci , vol.23 , pp. 8752-8758
    • Lu, Y.1    Perl, E.R.2
  • 43
    • 0035890005 scopus 로고    scopus 로고
    • Serotonin 5-HT(2) receptor activation induces a long-lasting amplification of spinal reflex actions in the rat
    • Machacek DW, Garraway SM, Shay BL, and Hochman S. Serotonin 5-HT(2) receptor activation induces a long-lasting amplification of spinal reflex actions in the rat. J Physiol 537: 201-207, 2001.
    • (2001) J Physiol , vol.537 , pp. 201-207
    • Machacek, D.W.1    Garraway, S.M.2    Shay, B.L.3    Hochman, S.4
  • 44
    • 24944572486 scopus 로고    scopus 로고
    • Spinal 5-HT2 receptor activation produces long-lasting modulation of the flexor-withdrawal reflex and changes in stiffness regulation
    • Machacek DW, Livingston BP, Hochman S, and Nichols TR. Spinal 5-HT2 receptor activation produces long-lasting modulation of the flexor-withdrawal reflex and changes in stiffness regulation. Soc Neurosci Abst 26: 152, 2000.
    • (2000) Soc Neurosci Abst , vol.26 , pp. 152
    • Machacek, D.W.1    Livingston, B.P.2    Hochman, S.3    Nichols, T.R.4
  • 45
    • 0036277865 scopus 로고    scopus 로고
    • Descending control of pain
    • Millan MJ. Descending control of pain. Prog Neurobiol 66: 355-474, 2002.
    • (2002) Prog Neurobiol , vol.66 , pp. 355-474
    • Millan, M.J.1
  • 46
    • 0029963263 scopus 로고    scopus 로고
    • Restoration of extensor excitability in the acute spinal cat by the 5-HT2 agonist DOI
    • Miller JF, Paul KD, Lee RH, Rymer WZ, and Heckman CJ. Restoration of extensor excitability in the acute spinal cat by the 5-HT2 agonist DOI. J Neurophysiol 75: 620-628, 1996.
    • (1996) J Neurophysiol , vol.75 , pp. 620-628
    • Miller, J.F.1    Paul, K.D.2    Lee, R.H.3    Rymer, W.Z.4    Heckman, C.J.5
  • 47
    • 0024158478 scopus 로고
    • The morphology and distribution of rat serotoninergic intraspinal neurons: An immunohistochemical study
    • Newton BW and Hamill RW. The morphology and distribution of rat serotoninergic intraspinal neurons: an immunohistochemical study. Brain Res Bull 20: 349-360, 1988.
    • (1988) Brain Res Bull , vol.20 , pp. 349-360
    • Newton, B.W.1    Hamill, R.W.2
  • 48
    • 0033548405 scopus 로고    scopus 로고
    • Reorganization of the primary afferent termination in the rat spinal dorsal horn during post-natal development
    • Park JS, Nakatsuka T, Nagata K, Higashi H, and Yoshimura M. Reorganization of the primary afferent termination in the rat spinal dorsal horn during post-natal development. Dev Brain Res 113: 29-36, 1999.
    • (1999) Dev Brain Res , vol.113 , pp. 29-36
    • Park, J.S.1    Nakatsuka, T.2    Nagata, K.3    Higashi, H.4    Yoshimura, M.5
  • 49
    • 0037289839 scopus 로고    scopus 로고
    • 5-HT2 receptors promote plateau potentials in turtle spinal motoneurons by facilitating an L-type calcium current
    • Perrier JF and Hounsgaard J. 5-HT2 receptors promote plateau potentials in turtle spinal motoneurons by facilitating an L-type calcium current. J Neurophysiol 89: 954-959, 2003.
    • (2003) J Neurophysiol , vol.89 , pp. 954-959
    • Perrier, J.F.1    Hounsgaard, J.2
  • 51
    • 0020623789 scopus 로고
    • Inhibitory mechanism in zebrafish optic tectum: Visual response properties of tectal cells altered by picrotoxin and bicuculline
    • Sajovic P and Levinthal C. Inhibitory mechanism in zebrafish optic tectum: visual response properties of tectal cells altered by picrotoxin and bicuculline. Brain Res 271: 227-240, 1983.
    • (1983) Brain Res , vol.271 , pp. 227-240
    • Sajovic, P.1    Levinthal, C.2
  • 52
    • 0034668699 scopus 로고    scopus 로고
    • The role of serotonin in reflex modulation and locomotor rhythm production in the mammalian spinal cord
    • Schmidt BJ and Jordan LM. The role of serotonin in reflex modulation and locomotor rhythm production in the mammalian spinal cord. Brain Res Bull 53: 689-710, 2000.
    • (2000) Brain Res Bull , vol.53 , pp. 689-710
    • Schmidt, B.J.1    Jordan, L.M.2
  • 53
    • 0017653980 scopus 로고
    • Effects of strychnine on the sodium conductance of the frog node of Ranvier
    • Shapiro BI. Effects of strychnine on the sodium conductance of the frog node of Ranvier. J Gen Physiol 69: 915-926, 1977.
    • (1977) J Gen Physiol , vol.69 , pp. 915-926
    • Shapiro, B.I.1
  • 54
    • 0031769620 scopus 로고    scopus 로고
    • Bioisosteric approach in the design of new dopaminergic/serotonergic ligands
    • Soskic V and Joksimovic J. Bioisosteric approach in the design of new dopaminergic/serotonergic ligands. Curr Med Chem 5: 493-512, 1998.
    • (1998) Curr Med Chem , vol.5 , pp. 493-512
    • Soskic, V.1    Joksimovic, J.2
  • 55
    • 0025250233 scopus 로고
    • Direct excitation of rat spinal motoneurones by serotonin
    • Takahashi T and Berger AJ. Direct excitation of rat spinal motoneurones by serotonin. J Physiol 423: 63-76, 1990.
    • (1990) J Physiol , vol.423 , pp. 63-76
    • Takahashi, T.1    Berger, A.J.2
  • 56
    • 0026643632 scopus 로고
    • Diverse actions of 5-hydroxytryptamine on frog spinal dorsal horn neurons in vitro
    • Tan H and Miletic V. Diverse actions of 5-hydroxytryptamine on frog spinal dorsal horn neurons in vitro. Neuroscience 49: 913-923, 1992.
    • (1992) Neuroscience , vol.49 , pp. 913-923
    • Tan, H.1    Miletic, V.2
  • 57
    • 0025354044 scopus 로고
    • Activity-dependent changes in rat ventral horn neurons in vitro; summation of prolonged afferent evoked postsynaptic depolarizations produce a D-2-amino-5-phosphonovaleric acid sensitive windup
    • Thompson SWN, King AE, and Woolf CJ. Activity-dependent changes in rat ventral horn neurons in vitro; summation of prolonged afferent evoked postsynaptic depolarizations produce a D-2-amino-5-phosphonovaleric acid sensitive windup. Eur J Neurosci 2: 638-649, 1990.
    • (1990) Eur J Neurosci , vol.2 , pp. 638-649
    • Thompson, S.W.N.1    King, A.E.2    Woolf, C.J.3
  • 58
    • 0037453204 scopus 로고    scopus 로고
    • 5-HT2A and 5-HT2C receptors and their atypical regulation properties
    • Van Oekelen D, Luyten WH, and Leysen JE. 5-HT2A and 5-HT2C receptors and their atypical regulation properties. Life Sci 72: 2429-2449, 2003.
    • (2003) Life Sci , vol.72 , pp. 2429-2449
    • Van Oekelen, D.1    Luyten, W.H.2    Leysen, J.E.3
  • 59
    • 0034703239 scopus 로고    scopus 로고
    • Inhibition of spinal protein kinase C blocks substance P-mediated hyperalgesia
    • Wajima Z, Hua XY, and Yaksh TL. Inhibition of spinal protein kinase C blocks substance P-mediated hyperalgesia. Brain Res 877: 314-321, 2000.
    • (2000) Brain Res , vol.877 , pp. 314-321
    • Wajima, Z.1    Hua, X.Y.2    Yaksh, T.L.3
  • 60
    • 0025059607 scopus 로고
    • 5-Hydroxytryptamine responses in neonate rat motoneurones in vitro
    • Wang MY and Dun NJ. 5-Hydroxytryptamine responses in neonate rat motoneurones in vitro. J Physiol 430: 87-103, 1990.
    • (1990) J Physiol , vol.430 , pp. 87-103
    • Wang, M.Y.1    Dun, N.J.2
  • 62
    • 0026616973 scopus 로고
    • 1C receptor-mediated facilitatory action on unit activity of ventral horn cells in rat spinal cord slices
    • 1C receptor-mediated facilitatory action on unit activity of ventral horn cells in rat spinal cord slices. Eur J Pharmacol 220: 237-242, 1992.
    • (1992) Eur J Pharmacol , vol.220 , pp. 237-242
    • Yamazaki, J.1    Fukuda, H.2    Nagao, T.3    Ono, H.4
  • 63
    • 0029045271 scopus 로고
    • 3H-phorbol 12,13-dibutyrate binding in spinal cord dorsal horn as well as persistent pain and hyperalgesia, which is reduced by inhibition of protein kinase C
    • 3H-phorbol 12,13-dibutyrate binding in spinal cord dorsal horn as well as persistent pain and hyperalgesia, which is reduced by inhibition of protein kinase C. J Neurosci 15: 3263-3272, 1995.
    • (1995) J Neurosci , vol.15 , pp. 3263-3272
    • Yashpal, K.1    Pitcher, G.M.2    Parent, A.3    Quirion, R.4    Coderre, T.J.5


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