-
1
-
-
4043152644
-
Steric stabilization of poly(2-(dimethylamino)ethyl methacrylate)-based polyplexes mediates prolonged circulation and tumor targeting in mice
-
DOI 10.1002/jgm.475
-
Verbaan FJ, Oussoren C, Snel CJ, Crommelin DJ, Hennink WE, Storm G. Steric stabilization of poly(2-(dimethylamino)ethyl methacrylate)-based polyplexes mediates prolonged circulation and tumor targeting in mice. J. Gene Med. 6(1), 64-75 (2004). (Pubitemid 40228004)
-
(2004)
Journal of Gene Medicine
, vol.6
, Issue.1
, pp. 64-75
-
-
Verbaan, F.J.1
Oussoren, C.2
Snel, C.J.3
Crommelin, D.J.A.4
Hennink, W.E.5
Storm, G.6
-
2
-
-
0032561334
-
Optimization of cell surface binding enhances efficiency and specificity of molecular conjugate gene delivery
-
DOI 10.1074/jbc.273.43.28004
-
Schaffer DV, Lauffenburger DA. Optimization of cell surface binding enhances effciency and specifcity of molecular conjugate gene delivery. J. Biol. Chem. 273(43), 28004-28009 (1998). (Pubitemid 28496092)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.43
, pp. 28004-28009
-
-
Schaffer, D.V.1
Lauffenburger, D.A.2
-
3
-
-
1642443376
-
Quantitative three-dimensional analysis of the intracellular trafficking of plasmid DNA transfected by a nonviral gene delivery system using confocal laser scanning microscopy
-
DOI 10.1016/j.ymthe.2004.01.005
-
Akita H, Ito R, Khalil IA, Futaki S, Harashima H. Quantitative three-dimensional analysis of the intracellular traffcking of plasmid DNA transfected by a nonviral gene delivery system using confocal laser scanning microscopy. Mol. Ther. 9(3), 443-451 (2004). (Pubitemid 38404534)
-
(2004)
Molecular Therapy
, vol.9
, Issue.3
, pp. 443-451
-
-
Akita, H.1
Ito, R.2
Khalil, I.A.3
Futaki, S.4
Harashima, H.5
-
4
-
-
33645528583
-
Quantitative comparison of intracellular traffcking and nuclear transcription between adenoviral and lipoplex systems
-
Hama S, Akita H, Ito R, Mizuguchi H, Hayakawa T, Harashima H. Quantitative comparison of intracellular traffcking and nuclear transcription between adenoviral and lipoplex systems. Mol. Ther. 13(4), 786-794 (2006).
-
(2006)
Mol. Ther.
, vol.13
, Issue.4
, pp. 786-794
-
-
Hama, S.1
Akita, H.2
Ito, R.3
Mizuguchi, H.4
Hayakawa, T.5
Harashima, H.6
-
5
-
-
77951916908
-
Balancing protection and release of DNA: Tools to address a bottleneck of non-viral gene delivery
-
Grigsby CL, Leong KW. Balancing protection and release of DNA: tools to address a bottleneck of non-viral gene delivery. J. R. Soc. Interface 7(Suppl. 1), S67-S82 (2010).
-
(2010)
J. R. Soc. Interface
, vol.7
, Issue.SUPPL. 1
-
-
Grigsby, C.L.1
Leong, K.W.2
-
6
-
-
10644240056
-
Formulation of chitosan-DNA nanoparticles with poly(propyl acrylic acid) enhances gene expression
-
DOI 10.1163/1568562042368112
-
Kiang T, Bright C, Cheung CY, Stayton PS, Hoffman AS, Leong KW. Formulation of chitosan-DNA nanoparticles with poly(propyl acrylic acid) enhances gene expression. J. Biomater. Sci. Polym. Ed. 15(11), 1405-1421 (2004). (Pubitemid 39654330)
-
(2004)
Journal of Biomaterials Science, Polymer Edition
, vol.15
, Issue.11
, pp. 1405-1421
-
-
Kiang, T.1
Bright, C.2
Cheung, C.Y.3
Stayton, P.S.4
Hoffman, A.S.5
Leong, K.W.6
-
8
-
-
0037331856
-
Dynamics of endocytosis and exocytosis of poly(D,L-lactide-co-glycolide) nanoparticles in vascular smooth muscle cells
-
DOI 10.1023/A:1022219003551
-
Panyam J, Labhasetwar V. Dynamics of endocytosis and exocytosis of poly(D,L-lactide-co-glycolide) nanoparticles in vascular smooth muscle cells. Pharm. Res. 20(2), 212-220 (2003). (Pubitemid 36277684)
-
(2003)
Pharmaceutical Research
, vol.20
, Issue.2
, pp. 212-220
-
-
Panyam, J.1
Labhasetwar, V.2
-
10
-
-
22744456996
-
Studying the intracellular dissociation of polymer-oligonucleotide complexes by dual color fluorescence fluctuation spectroscopy and confocal imaging
-
DOI 10.1021/bi0476883
-
Lucas B, Remaut K, Sanders NN, Braeckmans K, De Smedt SC, Demeester J. Studying the intracellular dissociation of polymer-oligonucleotide complexes by dual color fuorescence fuctuation spectroscopy and confocal imaging. Biochemistry 44(29), 9905-9912 (2005). (Pubitemid 41033457)
-
(2005)
Biochemistry
, vol.44
, Issue.29
, pp. 9905-9912
-
-
Lucas, B.1
Remaut, K.2
Sanders, N.N.3
Braeckmans, K.4
De Smedt, S.C.5
Demeester, J.6
-
11
-
-
14844330757
-
Towards a better understanding of the dissociation behavior of liposome-oligonucleotide complexes in the cytosol of cells
-
DOI 10.1016/j.jconrel.2004.12.017, PII S0168365904006352
-
Lucas B, Remaut K, Sanders NN, Braeckmans K, De Smedt SC, Demeester J. Towards a better understanding of the dissociation behavior of liposome-oligonucleotide complexes in the cytosol of cells. J. Control. Release 103 (2), 435-450 (2005). (Pubitemid 40342540)
-
(2005)
Journal of Controlled Release
, vol.103
, Issue.2
, pp. 435-450
-
-
Lucas, B.1
Remaut, K.2
Sanders, N.N.3
Braeckmans, K.4
De Smedt, S.C.5
Demeester, J.6
-
14
-
-
31144475647
-
Forster resonance energy transfer investigations using quantum-dot fuorophores
-
Clapp AR, Medintz IL, Mattoussi H. Forster resonance energy transfer investigations using quantum-dot fuorophores.Chemphyschem. 7(1), 47-57 (2006).
-
(2006)
Chemphyschem.
, vol.7
, Issue.1
, pp. 47-57
-
-
Clapp, A.R.1
Medintz, I.L.2
Mattoussi, H.3
-
15
-
-
25844525397
-
Multiplexed hybridization detection with multicolor colocalization of quantum dot nanoprobes
-
DOI 10.1021/nl050888v
-
Ho YP, Kung MC, Yang S, Wang TH. Multiplexed hybridization detection with multicolor colocalization of quantum dot nanoprobes. Nano Lett. 5(9), 1693-1697 (2005). (Pubitemid 41396148)
-
(2005)
Nano Letters
, vol.5
, Issue.9
, pp. 1693-1697
-
-
Ho, Y.-P.1
Kung, M.C.2
Yang, S.3
Wang, T.-H.4
-
16
-
-
0012392952
-
Semiconductor nanocrystals as fluorescent biological labels
-
DOI 10.1126/science.281.5385.2013
-
Bruchez M, Moronne M, Gin P, Weiss S, Alivisatos AP. Semiconductor nanocrystals as fuorescent biological labels. Science 281(5385), 2013-2016 (1998). (Pubitemid 28475485)
-
(1998)
Science
, vol.281
, Issue.5385
, pp. 2013-2016
-
-
Bruchez Jr., M.1
Moronne, M.2
Gin, P.3
Weiss, S.4
Alivisatos, A.P.5
-
17
-
-
0032566763
-
Quantum dot bioconjugates for ultrasensitive nonisotopic detection
-
DOI 10.1126/science.281.5385.2016
-
Chan WCW, Nie SM. Quantum dot bioconjugates for ultrasensitive nonisotopic detection. Science 281(5385), 2016-2018 (1998). (Pubitemid 28475486)
-
(1998)
Science
, vol.281
, Issue.5385
, pp. 2016-2018
-
-
Chan, W.C.W.1
Nie, S.2
-
18
-
-
33751226915
-
Evaluating the intracellular stability and unpacking of DNA nanocomplexes by quantum dots-FRET
-
DOI 10.1016/j.jconrel.2006.09.005, PII S0168365906004548
-
Ho YP, Chen HH, Leong KW, Wang TH. Evaluating the intracellular stability and unpacking of DNA nanocomplexes by quantum dots-FRET. J. Control Release 116(1), 83-89 (2006). (Pubitemid 44792304)
-
(2006)
Journal of Controlled Release
, vol.116
, Issue.1
, pp. 83-89
-
-
Ho, Y.-P.1
Chen, H.H.2
Leong, K.W.3
Wang, T.-H.4
-
19
-
-
84981779372
-
Intermolecular energy transference and fuorescence
-
Förster T. Intermolecular energy transference and fuorescence. Ann. Phys. 2, 55-75 (1948).
-
(1948)
Ann. Phys.
, vol.2
, pp. 55-75
-
-
Förster, T.1
-
20
-
-
57449119505
-
Quantum dot-based resonance energy transfer and its growing application in biology
-
Medintz IL, Mattoussi H. Quantum dot-based resonance energy transfer and its growing application in biology. Phys. Chem. Chem. Phys. 11(1), 17-45 (2009).
-
(2009)
Phys. Chem. Chem. Phys.
, vol.11
, Issue.1
, pp. 17-45
-
-
Medintz, I.L.1
Mattoussi, H.2
-
21
-
-
13644255249
-
Can luminescent quantum dots be efficient energy acceptors with organic dye donors?
-
DOI 10.1021/ja045676z
-
Clapp AR, Medintz IL, Fisher BR, Anderson GP, Mattoussi H. Can luminescent quantum dots be effcient energy acceptors with organic dye donors? J. Am. Chem. Soc. 127(4), 1242-1250 (2005). (Pubitemid 40228694)
-
(2005)
Journal of the American Chemical Society
, vol.127
, Issue.4
, pp. 1242-1250
-
-
Clapp, A.R.1
Medintz, I.L.2
Fisher, B.R.3
Anderson, G.P.4
Mattoussi, H.5
-
22
-
-
0036057165
-
Evaluation by fuorescence resonance energy transfer of the stability of nonviral gene delivery vectors under physiological conditions
-
Itaka K, Harada A, Nakamura K, Kawaguchi H, Kataoka K. Evaluation by fuorescence resonance energy transfer of the stability of nonviral gene delivery vectors under physiological conditions. Biomacromolecules 3(4), 841-845 (2002).
-
(2002)
Biomacromolecules
, vol.3
, Issue.4
, pp. 841-845
-
-
Itaka, K.1
Harada, A.2
Nakamura, K.3
Kawaguchi, H.4
Kataoka, K.5
-
23
-
-
20144373766
-
Non-viral gene delivery regulated by stiffness of cell adhesion substrates
-
DOI 10.1038/nmat1392
-
Kong HJ, Liu J, Riddle K, Matsumoto T, Leach K, Mooney DJ. Non-viral gene delivery regulated by stiffness of cell adhesion substrates. Nat. Mater. 4(6), 460-464 (2005). (Pubitemid 40774051)
-
(2005)
Nature Materials
, vol.4
, Issue.6
, pp. 460-464
-
-
Kong, H.J.1
Liu, J.2
Riddle, K.3
Matsumoto, T.4
Leach, K.5
Mooney, D.J.6
-
24
-
-
38649099106
-
Quantitative comparison of intracellular unpacking kinetics of polyplexes by a model constructed from quantum Dot-FRET
-
DOI 10.1038/sj.mt.6300392, PII 6300392
-
Chen HH, Ho YP, Jiang X, Mao HQ, Wang TH, Leong K W. Quantitative comparison of intracellular unpacking kinetics of polyplexes by a model constructed from quantum dot-FRET. Mol. Ther. 16(2), 324-332 (2008). (Pubitemid 351168042)
-
(2008)
Molecular Therapy
, vol.16
, Issue.2
, pp. 324-332
-
-
Chen, H.H.1
Ho, Y.-P.2
Jiang, X.3
Mao, H.-Q.4
Wang, T.-H.5
Leong, K.W.6
-
25
-
-
0035189482
-
Quantitative analysis of synthetic gene delivery vector design properties
-
DOI 10.1006/mthe.2001.0475
-
Lauffenburger DA, Varga CM, Hong K. Quantitative analysis of synthetic gene delivery vector design properties. Mol. Ther. 4(5), 438-446 (2001). (Pubitemid 33100281)
-
(2001)
Molecular Therapy
, vol.4
, Issue.5
, pp. 438-446
-
-
Varga, C.M.1
Hong, K.2
Lauffenburger, D.A.3
-
26
-
-
21744462256
-
Quantitative comparison of polyethylenimine formulations and adenoviral vectors in terms of intracellular gene delivery processes
-
DOI 10.1038/sj.gt.3302495
-
Lauffenburger DA, Varga CM, Tedford NC, Thomas M, Klibanov AM, Griffth LG. Quantitative comparison of polyethylenimine formulations and adenoviral vectors in terms of intracellular gene delivery processes. Gene. Ther. 12(13), 1023-1032 (2005). (Pubitemid 40946144)
-
(2005)
Gene Therapy
, vol.12
, Issue.13
, pp. 1023-1032
-
-
Varga, C.M.1
Tedford, N.C.2
Thomas, M.3
Klibanov, A.M.4
Griffith, L.G.5
Lauffenburger, D.A.6
-
27
-
-
33846796031
-
Understanding intracellular transport processes pertinent to synthetic gene delivery via stochastic simulations and sensitivity analyses
-
DOI 10.1529/biophysj.106.095521
-
Mitragotri S, Dinh AT, Pangarkar C, Theofanous T. Understanding intracellular transport processes pertinent to synthetic gene delivery via stochastic simulations and sensitivity analyses. Biophys. J. 92(3), 831-84 6 (20 07). (Pubitemid 46203213)
-
(2007)
Biophysical Journal
, vol.92
, Issue.3
, pp. 831-846
-
-
Dinh, A.-T.1
Pangarkar, C.2
Theofanous, T.3
Mitragotri, S.4
-
28
-
-
78650878303
-
Properties of PEI-based polyplex nanoparticles that correlate with their transfection effcacy
-
Ulasov AV, Khramtsov Y V, Trusov GA, Rosenkranz AA, Sverdlov ED, Sobolev AS. Properties of PEI-based polyplex nanoparticles that correlate with their transfection effcacy. Mol. Ther. 19(1), 103-112 (2011).
-
(2011)
Mol. Ther.
, vol.19
, Issue.1
, pp. 103-112
-
-
Ulasov, A.V.1
Khramtsov, Y.V.2
Trusov, G.A.3
Rosenkranz, A.A.4
Sverdlov, E.D.5
Sobolev, A.S.6
-
29
-
-
33745077164
-
High efficiency gene transfer using chitosan/DNA nanoparticles with specific combinations of molecular weight and degree of deacetylation
-
DOI 10.1016/j.biomaterials.2006.04.029, PII S0142961206003838
-
Lavertu M, Methot S, Tran-Khanh N, Buschmann MD. High effciency gene transfer using chitosan/DNA nanoparticles with specifc combinations of molecular weight and degree of deacetylation. Biomaterials 27(27), 4815-4824 (2006). (Pubitemid 43880352)
-
(2006)
Biomaterials
, vol.27
, Issue.27
, pp. 4815-4824
-
-
Lavertu, M.1
Methot, S.2
Tran-Khanh, N.3
Buschmann, M.D.4
-
30
-
-
44549088957
-
Quantum-dot-assisted fuorescence resonance energy transfer approach for intracellular traffcking of chitosan/DNA complex
-
Lee JI, Ha KS, Yoo HS. Quantum-dot-assisted fuorescence resonance energy transfer approach for intracellular traffcking of chitosan/DNA complex. Acta Biomater. 4(4), 791-798 (2008).
-
(2008)
Acta Biomater.
, vol.4
, Issue.4
, pp. 791-798
-
-
Lee, J.I.1
Ha, K.S.2
Yoo, H.S.3
-
31
-
-
38949194938
-
Intercalating dye as an acceptor in quantum-dot-mediated FRET
-
Lim TC, Bailey VJ, Ho YP, Wang TH. Intercalating dye as an acceptor in quantum-dot-mediated FRET. Nanotechnology 19 (7), 075701 (2008).
-
(2008)
Nanotechnology
, vol.19
, Issue.7
, pp. 075701
-
-
Lim, T.C.1
Bailey, V.J.2
Ho, Y.P.3
Wang, T.H.4
-
32
-
-
79954599765
-
Quantitative analysis of condensation/decondensation status of pDNA in the nuclear sub-domains by QD-FRET
-
Shaheen SM, Akita H, Yamashita A et al. Quantitative analysis of condensation/decondensation status of pDNA in the nuclear sub-domains by QD-FRET. Nucleic Acids Res. 39(7), e48 (2011).
-
(2011)
Nucleic Acids Res.
, vol.39
, Issue.7
-
-
Shaheen, S.M.1
Akita, H.2
Yamashita, A.3
-
33
-
-
77954283440
-
Dual-sensitive micellar nanoparticles regulate DNA unpacking and enhance gene-delivery effciency
-
Jiang X, Zheng Y, Chen HH, Leong KW, Wang TH, Mao HQ. Dual-sensitive micellar nanoparticles regulate DNA unpacking and enhance gene-delivery effciency. Adv. Mater. Weinheim 22(23), 2556-2560 (2010).
-
(2010)
Adv. Mater. Weinheim
, vol.22
, Issue.23
, pp. 2556-2560
-
-
Jiang, X.1
Zheng, Y.2
Chen, H.H.3
Leong, K.W.4
Wang, T.H.5
Mao, H.Q.6
-
34
-
-
63349092119
-
Simultaneous non-invasive ana lysis of DNA condensation and stability by two-step QD-FRET
-
Chen HH, Ho YP, Jiang X, Mao HQ, Wang TH, Leong KW. Simultaneous non-invasive ana lysis of DNA condensation and stability by two-step QD-FRET. Nano Today 4(2), 125-134 (2009).
-
(2009)
Nano Today
, vol.4
, Issue.2
, pp. 125-134
-
-
Chen, H.H.1
Ho, Y.P.2
Jiang, X.3
Mao, H.Q.4
Wang, T.H.5
Leong, K.W.6
-
35
-
-
77049109902
-
Intracellular traffcking and unpacking of siRNA/quantum dot-PEI complexes modifed with and without cell penetrating peptide: Confocal and fow cytometric FRET analysis
-
Lee H, Kim IK, Park TG. Intracellular traffcking and unpacking of siRNA/quantum dot-PEI complexes modifed with and without cell penetrating peptide: confocal and fow cytometric FRET analysis. Bioconjug. Chem. 21(2), 289-295 (2010).
-
(2010)
Bioconjug. Chem.
, vol.21
, Issue.2
, pp. 289-295
-
-
Lee, H.1
Kim, I.K.2
Park, T.G.3
-
36
-
-
49249113021
-
Quantum dot-amphipol nanocomplex for intracellular delivery and real-time imaging of siRNA
-
Qi L, Gao X. Quantum dot-amphipol nanocomplex for intracellular delivery and real-time imaging of siRNA. ACS Nano 2(7), 1403-1410 (2008).
-
(2008)
ACS Nano
, vol.2
, Issue.7
, pp. 1403-1410
-
-
Qi, L.1
Gao, X.2
-
37
-
-
80053536608
-
Uptake and intracellular fate of multifunctional nanoparticles: A comparison between lipoplexes and polyplexes via quantum dot mediated Förster resonance energy transfer
-
Wu Y, Ho YP, Mao Y et al. Uptake and intracellular fate of multifunctional nanoparticles: a comparison between lipoplexes and polyplexes via quantum dot mediated Förster resonance energy transfer. Mol. Pharm. 8 (5), 1662-1668 (2011).
-
(2011)
Mol. Pharm.
, vol.8
, Issue.5
, pp. 1662-1668
-
-
Wu, Y.1
Ho, Y.P.2
Mao, Y.3
-
38
-
-
79955122212
-
Sensing polymer/DNA polyplex dissociation using quantum dot fuorophores
-
Zhang B, Zhang Y, Mallapragada SK, Clapp AR. Sensing polymer/DNA polyplex dissociation using quantum dot fuorophores. ACS Nano 5(1), 129-138 (2011).
-
(2011)
ACS Nano
, vol.5
, Issue.1
, pp. 129-138
-
-
Zhang, B.1
Zhang, Y.2
Mallapragada, S.K.3
Clapp, A.R.4
-
39
-
-
65449165678
-
The convergence of quantum-dot-mediated fuorescence resonance energy transfer and microfuidics for monitoring DNA polyplex self-assembly in real time
-
Ho YP, Chen HH, Leong KW, Wang TH. The convergence of quantum-dot-mediated fuorescence resonance energy transfer and microfuidics for monitoring DNA polyplex self-assembly in real time. Nanotechnology 20(9), 095103 (2009).
-
(2009)
Nanotechnology
, vol.20
, Issue.9
, pp. 095103
-
-
Ho, Y.P.1
Chen, H.H.2
Leong, K.W.3
Wang, T.H.4
-
40
-
-
36248973801
-
Quantum dot-aptamer conjugates for synchronous cancer imaging, therapy, and sensing of drug delivery based on Bi-fluorescence resonance energy transfer
-
DOI 10.1021/nl071546n
-
Bagalkot V, Zhang L, Levy-Nissenbaum E et al. Quantum dot-aptamer conjugates for synchronous cancer imaging, therapy, and sensing of drug delivery based on bi-fuorescence resonance energy transfer. Nano Lett. 7(10), 3065-3070 (2007). (Pubitemid 350132931)
-
(2007)
Nano Letters
, vol.7
, Issue.10
, pp. 3065-3070
-
-
Bagalkot, V.1
Zhang, L.2
Levy-Nissenbaum, E.3
Jon, S.4
Kantoff, P.W.5
Langery, R.6
Farokhzad, O.C.7
-
41
-
-
33745663334
-
Labeling and Intracellular Tracking of Functionally Active Plasmid DNA with Semiconductor Quantum Dots
-
DOI 10.1016/j.ymthe.2006.03.010, PII S1525001606000931
-
Srinivasan C, Lee J, Papadimitrakopoulos F, Silbart LK, Zhao M, Burgess DJ. Labeling and intracellular tracking of functionally active plasmid DNA with semiconductor quantum dots. Mol. Ther. 14(2), 192-201 (2006). (Pubitemid 43964498)
-
(2006)
Molecular Therapy
, vol.14
, Issue.2
, pp. 192-201
-
-
Srinivasan, C.1
Lee, J.2
Papadimitrakopoulos, F.3
Silbart, L.K.4
Zhao, M.5
Burgess, D.J.6
-
43
-
-
46749091612
-
Bioconjugated quantum dots for in vivo molecular and cellular imaging
-
Smith AM, Duan H, Mohs AM, Nie S. Bioconjugated quantum dots for in vivo molecular and cellular imaging. Adv. Drug Delivery Rev. 60(11), 1226-1240 (2008).
-
(2008)
Adv. Drug Delivery Rev.
, vol.60
, Issue.11
, pp. 1226-1240
-
-
Smith, A.M.1
Duan, H.2
Mohs, A.M.3
Nie, S.4
-
44
-
-
19944433260
-
Quantum dots for live cells, in vivo imaging, and diagnostics
-
DOI 10.1126/science.1104274
-
Michalet X, Pinaud FF, Bentolila LA et al. Quantum dots for live cells, in vivo imaging, and diagnostics. Science 307(5709), 538-544 (2005). (Pubitemid 40165671)
-
(2005)
Science
, vol.307
, Issue.5709
, pp. 538-544
-
-
Michalet, X.1
Pinaud, F.F.2
Bentolila, L.A.3
Tsay, J.M.4
Doose, S.5
Li, J.J.6
Sundaresan, G.7
Wu, A.M.8
Gambhir, S.S.9
Weiss, S.10
-
45
-
-
78049392919
-
Quantum dot-based theranostics
-
Ho Y P, Leong KW. Quantum dot-based theranostics. Nanoscale 2(1), 60-68 (2010).
-
(2010)
Nanoscale
, vol.2
, Issue.1
, pp. 60-68
-
-
Ho, Y.P.1
Leong, K.W.2
|