Towards a better understanding of the dissociation behavior of liposome-oligonucleotide complexes in the cytosol of cells

Journal of Controlled Release

Volumn 103, Issue 2, 2005, Pages 435-450

  Lucas, B ^a   Remaut, K ^a   Sanders, N N ^a   Braeckmans, K ^a   De Smedt, S C ^a   Demeester, J ^a  

^a GHENT UNIVERSITY   (Belgium)

Author keywords

Antisense oligonucleotides; Fluorescence correlation spectroscopy (FCS); Gene therapy; Intracellular trafficking; Lipoplexes

Indexed keywords

ALCOHOLS; COMPLEXATION; FLUORESCENCE; POSITIVE IONS; QUENCHING; SPECTROSCOPIC ANALYSIS;

ANTISENSE THERAPY; CELL LYSATES; FLUORESCENCE FLUCTUATION SPECTROSCOPY (FFS); MICROINJECTION;

CELLS;

BUFFER; LIPOSOME; OLIGONUCLEOTIDE;

ANIMAL CELL; ARTICLE; BEHAVIOR; CELL LYSATE; CONTROLLED STUDY; CYTOPLASM; CYTOSOL; DISSOCIATION; DRUG DELIVERY SYSTEM; FLUORESCENCE FLUCTUATION SPECTROSCOPY; MEASUREMENT; MICROINJECTION; NONHUMAN; PRIORITY JOURNAL; SPECTROSCOPY; VERO CELL;

ANIMALS; BUFFERS; CATIONS; CERCOPITHECUS AETHIOPS; CYTOSOL; ELECTROPHORESIS, AGAR GEL; KINETICS; LIPOSOMES; MODELS, CHEMICAL; OLIGONUCLEOTIDES, ANTISENSE; SOLUBILITY; SPECTROMETRY, FLUORESCENCE; VERO CELLS;

EID: 14844330757     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2004.12.017     Document Type: Article

References (38)

1. C.A. Stein, and Y.C. Cheng Antisense oligonucleotides as therapeutic agents-is the bullet really magical Science 261 1993 1004 1012
2. S.M. Elbashir, J. Harborth, W. Lendeckel, A. Yalcin, K. Weber, and T. Tuschl Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells Nature 411 2001 494 498
3. J. Harborth, S.M. Elbashir, K. Vandenburgh, H. Manninga, S.A. Scaringe, K. Weber, and T. Tuschl Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing Antisense and Nucleic Acid Drug Development 13 2003 83 105
4. M. Miyagishi, M. Hayashi, and K. Taira Comparison of the suppressive effects of antisense oligonucleotides and siRNAs directed against the same targets in mammalian cells Antisense and Nucleic Acid Drug Development 13 2003 1 7
5. F. Shi, and D. Hoekstra Effective intracellular delivery of oligonucleotides in order to make sense of antisense Journal of Controlled Release 97 2004 189 209
6. P.L. Felgner, Y. Barenholz, J.P. Behr, S.H. Cheng, P. Cullis, L. Huang, J.A. Jessee, L. Seymour, F. Szoka, A.R. Thierry, E. Wagner, and G. Wu Nomenclature for synthetic gene delivery systems Human Gene Therapy 8 1997 511 512
7. J.G. Lewis, K.Y. Lin, A. Kothavale, W.M. Flanagan, M.D. Matteucci, R.B. DePrince, R.A. Mook, R.W. Hendren, and R.W. Wagner A serum-resistant cytofectin for cellular delivery of antisense oligodeoxynucleotides and plasmid DNA Proceedings of the National Academy of Sciences of the United States of America 93 1996 3176 3181
8. O. Meyer, D. Kirpotin, K.L. Hong, B. Sternberg, J.W. Park, M.C. Woodle, and D. Papahadjopoulos Cationic liposomes coated with polyethylene glycol as carriers for oligonucleotides Journal of Biological Chemistry 273 1998 15621 15627
9. M.C. De Oliveira, V. Boutet, E. Fattal, D. Boquet, J.M. Grognet, P. Couvreur, and J.R. Deverre Improvement of in vivo stability of phosphodiester oligonucleotide using anionic liposomes in mice Life Sciences 67 2000 1625 1637
10. P.C. Gokhale, V. Soldatenkov, F.H. Wang, A. Rahman, A. Dritschilo, and U. Kasid Antisense Raf oligodeoxyribonucleotide is protected by liposomal encapsulation and inhibits Raf-1 protein expression in vitro and in vivo: implication for gene therapy of radioresistant cancer Gene Therapy 4 1997 1289 1299
11. O. Zelphati, and F.C. Szoka Intracellular distribution and mechanism of delivery of oligonucleotides mediated by cationic lipids Pharmaceutical Research 13 1996 1367 1372
12. E.G. Marcusson, B. Bhat, M. Manoharan, C.F. Bennett, and N.M. Dean Phosphorothioate oligodeoxyribonucleotides dissociate from cationic lipids before entering the nucleus Nucleic Acids Research 26 1998 2016 2023
13. O. Zelphati, and F.C. Szoka Mechanism of oligonucleotide release from cationic liposomes Proceedings of the National Academy of Sciences of the United States of America 93 1996 11493 11498
14. F.C. Szoka, Y.H. Xu, and O. Zelphati How are nucleic acids released in cells from cationic lipid-nucleic acid complexes? Advanced Drug Delivery Reviews 24 1997 291
15. N.N. Sanders, E. Van Rompaey, S.C. De Smedt, and J. Demeester Structural alterations of gene complexes by cystic fibrosis sputum American Journal of Respiratory and Critical Care Medicine 164 2001 486 493
16. T. Okuda, T. Niidome, and H. Aoyagi Cytosolic soluble proteins induce DNA release from DNA-gene carrier complexes Journal of Controlled Release 98 2004 325 332
17. F.X. Shi, W.H. Visser, N.M.J. de Jong, R.S.B. Liem, E. Ronken, and D. Hoekstra Antisense oligonucleotides reach mRNA targets via the RNA matrix: downregulation of the 5-HT1A receptor Experimental Cell Research 291 2003 313 325
18. B. Lucas, E. Van Rompaey, S.C. De Smedt, J. Demeester, and P. Van Oostveldt Dual-color fluorescence fluctuation spectroscopy to study the complexation between poly-l-lysine and oligonucleotides Macromolecules 35 2002 8152 8160
19. B. Lucas, K. Remaut, K. Braeckmans, J. Haustraete, S.C. De Smedt, and J. Demeester Studying pegylated DNA-complexes by dual color fluorescence correlation spectroscopy Macromolecules 37 2004 3832 3840
20. E. Van Rompaey, N. Sanders, S.C. De Smedt, J. Demeester, E. Van Craenenbroeck, and Y. Engelborghs Complex formation between cationic polymethacrylates and oligonucleotides Macromolecules 33 2000 8280 8288
21. E. Van Rompaey, Y. Engelborghs, N. Sanders, S.C. De Smedt, and J. Demeester Interactions between oligonucleotides and cationic polymers investigated by fluorescence correlation spectroscopy Pharmaceutical Research 18 2001 928 936
22. E. Van Rompaey, Y. Chen, J.D. Muller, E. Gratton, E. Van Craenenbroeck, Y. Engelborghs, S. DeSmedt, and J. Demeester Fluorescence fluctuation analysis for the study of interactions between oligonucleotides and polycationic polymers Biological Chemistry 382 2001 379 386
23. J.P. Clamme, J. Azoulay, and Y. Mely Monitoring of the formation and dissociation of polyethylenimine/DNA complexes by two photon fluorescence correlation spectroscopy Biophysical Journal 84 2003 1960 1968
24. T. Kral, M. Langner, M. Benes, D. Baczynska, M. Ugorski, and M. Hof The application of fluorescence correlation spectroscopy in detecting DNA condensation Biophysical Chemistry 95 2002 135 144
25. P. Jurkiewicz, A. Okruszek, M. Hof, and M. Langner Associating oligonucleotides with positively charged liposomes Cellular and Molecular Biology Letters 8 2003 77 84
26. D. Merkle, S.P. Lees-Miller, and D.T. Cramb Structure and dynamics of lipoplex formation examined using two-photon fluorescence cross-correlation spectroscopy Biochemistry 43 2004 7263 7272
27. P. Schwille, F.J. MeyerAlmes, and R. Rigler Dual-color fluorescence cross-correlation spectroscopy for multicomponent diffusional analysis in solution Biophysical Journal 72 1997 1878 1886
28. S.T. Hess, S.H. Huang, A.A. Heikal, and W.W. Webb Biological and chemical applications of fluorescence correlation spectroscopy: a review Biochemistry 41 2002 697 705
29. P. Schwille Fluorescence correlation spectroscopy and its potential for intracellular applications Cell Biochemistry and Biophysics 34 2001 383 408
30. O. Zelphati, and F.C. Szoka Mechanism of oligonucleotide release from cationic liposomes Proceedings of the National Academy of Sciences of the United States of America 93 1996 11493 11498
31. U. Meseth, T. Wohland, R. Rigler, and H. Vogel Resolution of fluorescence correlation measurements Biophysical Journal 76 1999 1619 1631
32. J.C. Politz, E.S. Browne, D.E. Wolf, and T. Pederson Intranuclear diffusion and hybridization state of oligonucleotides measured by fluorescence correlation spectroscopy in living cells Proceedings of the National Academy of Sciences of the United States of America 95 1998 6043 6048
33. E. Van Craenenbroeck, G. Matthys, J. Beirlant, and Y. Engelborghs A statistical analysis of fluorescence correlation data Journal of Fluorescence 9 1999 325 331
34. J.P. Clarenc, B. Lebleu, and J.P. Leonetti Characterization of the nuclear-binding sites of oligodeoxyribonucleotides and their analogs Journal of Biological Chemistry 268 1993 5600 5604
35. R. Hartig, R.L. Shoeman, A. Janetzko, S. Grub, and P. Traub Active nuclear import of single-stranded oligonucleotides and their complexes with non-karyophilic macromolecules Biology of the Cell 90 1998 407 426
36. P. Lorenz, B.F. Baker, C.F. Bennett, and D.L. Spector Phosphorothioate antisense oligonucleotides induce the formation of nuclear bodies Molecular Biology of the Cell 9 1998 1007 1023
37. A. Tsuji, H. Koshimoto, Y. Sato, M. Hirano, Y. Sei-Iida, S. Kondo, and K. Ishibashi Direct observation of specific messenger RNA in a single living cell under a fluorescence microscope Biophysical Journal 78 2000 3260 3274
38. J.P. Leonetti, N. Mechti, G. Degols, C. Gagnor, and B. Lebleu Intracellular-distribution of microinjected antisense oligonucleotides Proceedings of the National Academy of Sciences of the United States of America 88 1991 2702 2706