-
1
-
-
0027480960
-
A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
-
HDCRG
-
HDCRG A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes Cell 72 1993 971 983
-
(1993)
Cell
, vol.72
, pp. 971-983
-
-
-
2
-
-
44649113000
-
Huntington's disease. Part 3: Family aspects of HD
-
A. Aubeeluck, and C.B. Moskowitz Huntington's disease. Part 3: family aspects of HD Br J Nurs 17 2008 328 331
-
(2008)
Br J Nurs
, vol.17
, pp. 328-331
-
-
Aubeeluck, A.1
Moskowitz, C.B.2
-
3
-
-
0038701684
-
Huntingtin aggregation and toxicity in Huntington's disease
-
G. Bates Huntingtin aggregation and toxicity in Huntington's disease Lancet 361 2003 1642 1644
-
(2003)
Lancet
, vol.361
, pp. 1642-1644
-
-
Bates, G.1
-
4
-
-
28644433087
-
Normal huntingtin function: An alternative approach to Huntington's disease
-
E. Cattaneo, C. Zuccato, and M. Tartari Normal huntingtin function: an alternative approach to Huntington's disease Nat Rev Neurosci 6 2005 919 930
-
(2005)
Nat Rev Neurosci
, vol.6
, pp. 919-930
-
-
Cattaneo, E.1
Zuccato, C.2
Tartari, M.3
-
5
-
-
18544410106
-
Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation
-
S.W. Davies, M. Turmaine, B.A. Cozens, M. DiFiglia, A.H. Sharp, and C.A. Ross Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation Cell 90 1997 537 548
-
(1997)
Cell
, vol.90
, pp. 537-548
-
-
Davies, S.W.1
Turmaine, M.2
Cozens, B.A.3
Difiglia, M.4
Sharp, A.H.5
Ross, C.A.6
-
6
-
-
27144534486
-
Full motor recovery despite striatal neuron loss and formation of irreversible amyloid-like inclusions in a conditional mouse model of Huntington's disease
-
M. Diaz-Hernandez, J. Torres-Peraza, A. Salvatori-Abarca, M.A. Moran, P. Gomez-Ramos, and J. Alberch Full motor recovery despite striatal neuron loss and formation of irreversible amyloid-like inclusions in a conditional mouse model of Huntington's disease J Neurosci 25 2005 9773 9781
-
(2005)
J Neurosci
, vol.25
, pp. 9773-9781
-
-
Diaz-Hernandez, M.1
Torres-Peraza, J.2
Salvatori-Abarca, A.3
Moran, M.A.4
Gomez-Ramos, P.5
Alberch, J.6
-
7
-
-
0028989602
-
Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons
-
M. DiFiglia, E. Sapp, K. Chase, C. Schwarz, A. Meloni, and C. Young Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons Neuron 14 1995 1075 1081
-
(1995)
Neuron
, vol.14
, pp. 1075-1081
-
-
Difiglia, M.1
Sapp, E.2
Chase, K.3
Schwarz, C.4
Meloni, A.5
Young, C.6
-
8
-
-
0030752709
-
Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain
-
M. DiFiglia, E. Sapp, K.O. Chase, S.W. Davies, G.P. Bates, and J.P. Vonsattel Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain Science 277 1997 1990 1993
-
(1997)
Science
, vol.277
, pp. 1990-1993
-
-
Difiglia, M.1
Sapp, E.2
Chase, K.O.3
Davies, S.W.4
Bates, G.P.5
Vonsattel, J.P.6
-
9
-
-
0026320986
-
Proliferative and degenerative changes in striatal spiny neurons in Huntington's disease: A combined study using the section-Golgi method and calbindin D28k immunocytochemistry
-
R.J. Ferrante, N.W. Kowall, and E.P. Richardson Jr. Proliferative and degenerative changes in striatal spiny neurons in Huntington's disease: a combined study using the section-Golgi method and calbindin D28k immunocytochemistry J Neurosci 11 1991 3877 3887
-
(1991)
J Neurosci
, vol.11
, pp. 3877-3887
-
-
Ferrante, R.J.1
Kowall, N.W.2
Richardson, Jr.E.P.3
-
10
-
-
0027359989
-
Molecular analysis of new mutations for Huntington's disease: Intermediate alleles and sex of origin effects
-
Y.P. Goldberg, B. Kremer, S.E. Andrew, J. Theilmann, R.K. Graham, and F. Squitieri Molecular analysis of new mutations for Huntington's disease: intermediate alleles and sex of origin effects Nat Genet 5 1993 174 179
-
(1993)
Nat Genet
, vol.5
, pp. 174-179
-
-
Goldberg, Y.P.1
Kremer, B.2
Andrew, S.E.3
Theilmann, J.4
Graham, R.K.5
Squitieri, F.6
-
11
-
-
0035740965
-
Neuroprotective therapy for Huntington's disease: New prospects and challenges
-
S.M. Hersch, and H.D. Rosas Neuroprotective therapy for Huntington's disease: new prospects and challenges Expert Rev Neurother 1 2001 111 118
-
(2001)
Expert Rev Neurother
, vol.1
, pp. 111-118
-
-
Hersch, S.M.1
Rosas, H.D.2
-
12
-
-
41249101172
-
Neuroprotection for Huntington's disease: Ready, set, slow
-
S.M. Hersch, and H.D. Rosas Neuroprotection for Huntington's disease: ready, set, slow Neurotherapeutics 5 2008 226 236
-
(2008)
Neurotherapeutics
, vol.5
, pp. 226-236
-
-
Hersch, S.M.1
Rosas, H.D.2
-
13
-
-
33644783812
-
Regional and cellular gene expression changes in human Huntington's disease brain
-
A. Hodges, A.D. Strand, A.K. Aragaki, A. Kuhn, T. Sengstag, and G. Hughes Regional and cellular gene expression changes in human Huntington's disease brain Hum Mol Genet 15 2006 965 977
-
(2006)
Hum Mol Genet
, vol.15
, pp. 965-977
-
-
Hodges, A.1
Strand, A.D.2
Aragaki, A.K.3
Kuhn, A.4
Sengstag, T.5
Hughes, G.6
-
14
-
-
34249715853
-
Huntingtin interacting proteins are genetic modifiers of neurodegeneration
-
L.S. Kaltenbach, E. Romero, R.R. Becklin, R. Chettier, R. Bell, and A. Phansalkar Huntingtin interacting proteins are genetic modifiers of neurodegeneration PLoS Genet 3 2007 e82
-
(2007)
PLoS Genet
, vol.3
, pp. 82
-
-
Kaltenbach, L.S.1
Romero, E.2
Becklin, R.R.3
Chettier, R.4
Bell, R.5
Phansalkar, A.6
-
15
-
-
38749149622
-
Cellular pathways leading to neuronal dysfunction and degeneration
-
A.G. Kazantsev Cellular pathways leading to neuronal dysfunction and degeneration Drug News Perspect 20 2007 501 509
-
(2007)
Drug News Perspect
, vol.20
, pp. 501-509
-
-
Kazantsev, A.G.1
-
16
-
-
53249130741
-
Therapeutic application of histone deacetylase inhibitors for central nervous system disorders
-
A.G. Kazantsev, and L.M. Thompson Therapeutic application of histone deacetylase inhibitors for central nervous system disorders Nat Rev Drug Discov 7 2008 854 868
-
(2008)
Nat Rev Drug Discov
, vol.7
, pp. 854-868
-
-
Kazantsev, A.G.1
Thompson, L.M.2
-
17
-
-
0028316870
-
A worldwide study of the Huntington's disease mutation. The sensitivity and specificity of measuring CAG repeats
-
B. Kremer, P. Goldberg, S.E. Andrew, J. Theilmann, H. Telenius, and J. Zeisler A worldwide study of the Huntington's disease mutation. The sensitivity and specificity of measuring CAG repeats N Engl J Med 330 1994 1401 1406
-
(1994)
N Engl J Med
, vol.330
, pp. 1401-1406
-
-
Kremer, B.1
Goldberg, P.2
Andrew, S.E.3
Theilmann, J.4
Telenius, H.5
Zeisler, J.6
-
18
-
-
0028080406
-
Trinucleotide repeat expansion in neurological disease
-
A.R. La Spada, H.L. Paulson, and K.H. Fischbeck Trinucleotide repeat expansion in neurological disease Ann Neurol 36 1994 814 822
-
(1994)
Ann Neurol
, vol.36
, pp. 814-822
-
-
La Spada, A.R.1
Paulson, H.L.2
Fischbeck, K.H.3
-
19
-
-
56149120246
-
Linking SNPs to CAG repeat length in Huntington's disease patients
-
W. Liu, L.A. Kennington, H.D. Rosas, S. Hersch, J.H. Cha, and P.D. Zamore Linking SNPs to CAG repeat length in Huntington's disease patients Nat Methods 5 2008 951 953
-
(2008)
Nat Methods
, vol.5
, pp. 951-953
-
-
Liu, W.1
Kennington, L.A.2
Rosas, H.D.3
Hersch, S.4
Cha, J.H.5
Zamore, P.D.6
-
20
-
-
70649097387
-
RNAi applications in therapy development for neurodegenerative disease
-
M.M. Maxwell RNAi applications in therapy development for neurodegenerative disease Curr Pharm Des 15 2009 3977 3991
-
(2009)
Curr Pharm des
, vol.15
, pp. 3977-3991
-
-
Maxwell, M.M.1
-
21
-
-
0037014426
-
Protein misfolding, amyloid formation, and neurodegeneration: A critical role for molecular chaperones?
-
P.J. Muchowski Protein misfolding, amyloid formation, and neurodegeneration: a critical role for molecular chaperones? Neuron 35 2002 9 12
-
(2002)
Neuron
, vol.35
, pp. 9-12
-
-
Muchowski, P.J.1
-
22
-
-
0035937523
-
Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity
-
F.C. Nucifora Jr., M. Sasaki, M.F. Peters, H. Huang, J.K. Cooper, and M. Yamada Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity Science 291 2001 2423 2428
-
(2001)
Science
, vol.291
, pp. 2423-2428
-
-
Nucifora Jr., F.C.1
Sasaki, M.2
Peters, M.F.3
Huang, H.4
Cooper, J.K.5
Yamada, M.6
-
23
-
-
33749437310
-
Apoptotic cascades as possible targets for inhibiting cell death in Huntington's disease
-
L.R. Pattison, M.R. Kotter, D. Fraga, and R.M. Bonelli Apoptotic cascades as possible targets for inhibiting cell death in Huntington's disease J Neurol 253 2006 1137 1142
-
(2006)
J Neurol
, vol.253
, pp. 1137-1142
-
-
Pattison, L.R.1
Kotter, M.R.2
Fraga, D.3
Bonelli, R.M.4
-
24
-
-
77952899450
-
Role of tetrabenazine for Huntington's disease-associated chorea
-
L.H. Poon, G.A. Kang, and A.J. Lee Role of tetrabenazine for Huntington's disease-associated chorea Ann Pharmacother 44 2010 1080 1089
-
(2010)
Ann Pharmacother
, vol.44
, pp. 1080-1089
-
-
Poon, L.H.1
Kang, G.A.2
Lee, A.J.3
-
25
-
-
57649198470
-
Complexity and heterogeneity: What drives the ever-changing brain in Huntington's disease?
-
H.D. Rosas, D.H. Salat, S.Y. Lee, A.K. Zaleta, N. Hevelone, and S.M. Hersch Complexity and heterogeneity: what drives the ever-changing brain in Huntington's disease? Ann N Y Acad Sci 1147 2008 196 205
-
(2008)
Ann N y Acad Sci
, vol.1147
, pp. 196-205
-
-
Rosas, H.D.1
Salat, D.H.2
Lee, S.Y.3
Zaleta, A.K.4
Hevelone, N.5
Hersch, S.M.6
-
26
-
-
18544400323
-
Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo
-
E. Scherzinger, R. Lurz, M. Turmaine, L. Mangiarini, B. Hollenbach, and R. Hasenbank Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo Cell 90 1997 549 558
-
(1997)
Cell
, vol.90
, pp. 549-558
-
-
Scherzinger, E.1
Lurz, R.2
Turmaine, M.3
Mangiarini, L.4
Hollenbach, B.5
Hasenbank, R.6
-
27
-
-
37849030901
-
Polyglutamine diseases: Emerging concepts in pathogenesis and therapy
-
J. Shao, and M.I. Diamond Polyglutamine diseases: emerging concepts in pathogenesis and therapy Hum Mol Genet 16 2007 R115 R123 (Spec. No. 2)
-
(2007)
Hum Mol Genet
, vol.16
-
-
Shao, J.1
Diamond, M.I.2
-
28
-
-
12944263711
-
The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription
-
J.S. Steffan, A. Kazantsev, O. Spasic-Boskovic, M. Greenwald, Y.Z. Zhu, and H. Gohler The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription Proc Natl Acad Sci U S A 97 2000 6763 6768
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 6763-6768
-
-
Steffan, J.S.1
Kazantsev, A.2
Spasic-Boskovic, O.3
Greenwald, M.4
Zhu, Y.Z.5
Gohler, H.6
-
29
-
-
49349110821
-
Huntington's disease: Revisiting the aggregation hypothesis in polyglutamine neurodegenerative diseases
-
R. Truant, R.S. Atwal, C. Desmond, L. Munsie, and T. Tran Huntington's disease: revisiting the aggregation hypothesis in polyglutamine neurodegenerative diseases FEBS J 275 2008 4252 4262
-
(2008)
FEBS J
, vol.275
, pp. 4252-4262
-
-
Truant, R.1
Atwal, R.S.2
Desmond, C.3
Munsie, L.4
Tran, T.5
-
30
-
-
0034737299
-
Reversal of neuropathology and motor dysfunction in a conditional model of Huntington's disease
-
A. Yamamoto, J.J. Lucas, and R. Hen Reversal of neuropathology and motor dysfunction in a conditional model of Huntington's disease Cell 101 2000 57 66
-
(2000)
Cell
, vol.101
, pp. 57-66
-
-
Yamamoto, A.1
Lucas, J.J.2
Hen, R.3
|