Determination of acetylcholinesterase activity by the Ellman assay: A versatile tool for in vitro research on medical countermeasures against organophosphate poisoning

Drug Testing and Analysis

Volumn 4, Issue 3-4, 2012, Pages 282-291

  Worek, Franz ^a   Eyer, Peter ^b   Thiermann, Horst ^a  

^a BUNDESWEHR INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY   (Germany)

^b UNIVERSITY OF MUNICH   (Germany)

Author keywords

Acetylcholinesterase; Ellman assay; Enzyme kinetics; Organophosphorus compounds; Oximes

Indexed keywords

DIAGNOSIS; KINETICS; PHOSPHORUS COMPOUNDS; RATE CONSTANTS;

ACETYLCHOLINESTERASE; ACETYLCHOLINESTERASE ACTIVITY; ELLMAN ASSAY; ENZYMES KINETICS; IN-VITRO; MECHANISM OF ACTION; MEDICAL COUNTERMEASURES; ORGANOPHOSPHORUS COMPOUNDS; OXIME; VERSATILE TOOLS;

ENZYME KINETICS;

ACETYLCHOLINESTERASE; HEMOGLOBIN; ORGANOPHOSPHATE; OXIME;

BREATHING MUSCLE; ELLMAN ASSAY; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INHIBITION; ENZYME KINETICS; ENZYME SUBSTRATE; HUMAN; IN VITRO STUDY; INTOXICATION; NONHUMAN; PH; PRIORITY JOURNAL; REPRODUCIBILITY; SHORT SURVEY; SPECTROPHOTOMETRY; TEMPERATURE;

EID: 84859299638     PISSN: 19427603     EISSN: 19427611     Source Type: Journal    
DOI: 10.1002/dta.337     Document Type: Short Survey

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