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Volumn 107, Issue 1-3, 1999, Pages 233-239

Modern strategies in therapy of organophosphate poisoning

Author keywords

Obidoxime; Organophosphate poisoning; Oxydemeton methyl; Parathion; Pralidoxime

Indexed keywords

ACETYLCHOLINESTERASE; ATROPINE; ERYTHROCYTE ENZYME; OBIDOXIME; ORGANOPHOSPHATE; OXYDEMETON METHYL; PARATHION; PRALIDOXIME; UNCLASSIFIED DRUG;

EID: 0032994808     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4274(99)00052-1     Document Type: Conference Paper
Times cited : (149)

References (23)
  • 1
    • 0028813953 scopus 로고
    • Efficacy of obidoxime in human organophosphate poisoning: Determination by neuromuscular transmission studies
    • Besser R., Weilemann L., Gutman L. Efficacy of obidoxime in human organophosphate poisoning: determination by neuromuscular transmission studies. Muscle Nerve. 18:1995;15-22.
    • (1995) Muscle Nerve , vol.18 , pp. 15-22
    • Besser, R.1    Weilemann, L.2    Gutman, L.3
  • 2
    • 0344502295 scopus 로고
    • Plasma pralidoxime concentrations following bolus injection and continuous infusion
    • Casey P.B., Gosden E., Blakey L., Thompson J.P., Vale J.A. Plasma pralidoxime concentrations following bolus injection and continuous infusion. Przeg. Lek. 52:1995;203.
    • (1995) Przeg. Lek. , vol.52 , pp. 203
    • Casey, P.B.1    Gosden, E.2    Blakey, L.3    Thompson, J.P.4    Vale, J.A.5
  • 3
    • 0345366932 scopus 로고
    • Late reactivation of erythrocyte cholinesterase activity by pralidoxime in a case of chlorpyrifos poisoning
    • Casey P.B., Blakey L., Bradberry S.M., Vale J.A. Late reactivation of erythrocyte cholinesterase activity by pralidoxime in a case of chlorpyrifos poisoning. Przeg. Lek. 52:1995;206.
    • (1995) Przeg. Lek. , vol.52 , pp. 206
    • Casey, P.B.1    Blakey, L.2    Bradberry, S.M.3    Vale, J.A.4
  • 4
    • 0002378365 scopus 로고    scopus 로고
    • Optimal oxime dosage regimen, a pharmacokinetic approach
    • L. Szinicz, P. Eyer, & R. Klimmek. Heidelberg: Spektrum
    • Eyer P. Optimal oxime dosage regimen, a pharmacokinetic approach. Szinicz L., Eyer P., Klimmek R. Role of Oximes in the Treatment of Anticholinesterase Agent Poisoning. 1996;33-51 Spektrum, Heidelberg.
    • (1996) Role of Oximes in the Treatment of Anticholinesterase Agent Poisoning , pp. 33-51
    • Eyer, P.1
  • 5
    • 0032407286 scopus 로고    scopus 로고
    • Enzyme-based assay for quantification of paraoxon in blood of parathion poisoned patients
    • Eyer, F., Eyer, P., 1998. Enzyme-based assay for quantification of paraoxon in blood of parathion poisoned patients. Hum. Exp. Toxicol. 17, 646-651.
    • (1998) Hum. Exp. Toxicol. , vol.17 , pp. 646-651
    • Eyer, F.1    Eyer, P.2
  • 9
    • 0029936225 scopus 로고    scopus 로고
    • Pharmacokinetics following a loading plus a continuous infusion of pralidoxime compared with the traditional short infusion regimen in human volunteers
    • Medicis J.J., Stork C.M., Howland M.A., Hoffman R.S., Goldfrank L.R. Pharmacokinetics following a loading plus a continuous infusion of pralidoxime compared with the traditional short infusion regimen in human volunteers. Clin. Toxicol. 34:1996;289-295.
    • (1996) Clin. Toxicol. , vol.34 , pp. 289-295
    • Medicis, J.J.1    Stork, C.M.2    Howland, M.A.3    Hoffman, R.S.4    Goldfrank, L.R.5
  • 10
    • 0345364589 scopus 로고
    • Pharmacokinetics and laboratory findings during continuous infusion of obidoxime and atropine in a patient with severe oxydemeton methyl poisoning
    • Pfab R., Felgenhauer N., Zilker T., Mast U., Thiermann H., Eyer P. Pharmacokinetics and laboratory findings during continuous infusion of obidoxime and atropine in a patient with severe oxydemeton methyl poisoning. Przeg. Lek. 52:1995;202-203.
    • (1995) Przeg. Lek. , vol.52 , pp. 202-203
    • Pfab, R.1    Felgenhauer, N.2    Zilker, T.3    Mast, U.4    Thiermann, H.5    Eyer, P.6
  • 11
    • 0028821653 scopus 로고
    • Separation of geometrical syn/anti isomers of obidoxime by ion-pair high-performance liquid chromatography
    • Spöhrer U., Eyer P. Separation of geometrical syn/anti isomers of obidoxime by ion-pair high-performance liquid chromatography. J. Chromatogr. A. 693:1995;55-61.
    • (1995) J. Chromatogr. a , vol.693 , pp. 55-61
    • Spöhrer, U.1    Eyer, P.2
  • 12
    • 49749224256 scopus 로고
    • Minimum concentrations of N-methyl-pyridinium-2-aldoxime methanesulphonate (P2S) which reverse neuromuscular block
    • Sundwall A. Minimum concentrations of N-methyl-pyridinium-2-aldoxime methanesulphonate (P2S) which reverse neuromuscular block. Biochem. Pharmacol. 8:1961;413-417.
    • (1961) Biochem. Pharmacol. , vol.8 , pp. 413-417
    • Sundwall, A.1
  • 14
    • 0030062278 scopus 로고    scopus 로고
    • Pharmacokinetics of atropine in dogs after i.m. injection with newly developed dry/wet combination autoinjectors containing HI 6 or HLö 7
    • Thiermann H., Radtke M., Spöhrer U., Klimmek R., Eyer P. Pharmacokinetics of atropine in dogs after i.m. injection with newly developed dry/wet combination autoinjectors containing HI 6 or HLö 7. Arch. Toxicol. 70:1996;293-299.
    • (1996) Arch. Toxicol. , vol.70 , pp. 293-299
    • Thiermann, H.1    Radtke, M.2    Spöhrer, U.3    Klimmek, R.4    Eyer, P.5
  • 15
    • 0030759083 scopus 로고    scopus 로고
    • Cholinesterase status, pharmakokinetics and laboratory findings during obidoxime therapy in organophosphate poisoned patients
    • Thiermann H., Mast U., Klimmek R., Eyer P., Hibler A., Pfab R., Felgenhauer N., Zilker T. Cholinesterase status, pharmakokinetics and laboratory findings during obidoxime therapy in organophosphate poisoned patients. Hum. Exp. Toxicol. 16:1997;473-480.
    • (1997) Hum. Exp. Toxicol. , vol.16 , pp. 473-480
    • Thiermann, H.1    Mast, U.2    Klimmek, R.3    Eyer, P.4    Hibler, A.5    Pfab, R.6    Felgenhauer, N.7    Zilker, T.8
  • 16
    • 0344933183 scopus 로고
    • Oximes-useless and harmful?
    • Vale J.A. Oximes-useless and harmful? Przeg. Lek. 52:1995;201.
    • (1995) Przeg. Lek. , vol.52 , pp. 201
    • Vale, J.A.1
  • 17
    • 0002571342 scopus 로고    scopus 로고
    • Rationale for oxime therapy: Pralidoxime as an antidote in OP insecticide poisoning
    • Vale J.A. Rationale for oxime therapy: pralidoxime as an antidote in OP insecticide poisoning. Hum. Exp. Toxicol. 15:1996;77.
    • (1996) Hum. Exp. Toxicol. , vol.15 , pp. 77
    • Vale, J.A.1
  • 18
    • 0027535594 scopus 로고
    • Cholinesterase reactivation in organophosphorus poisoned patients depends on the plasma concentration of the oxime pralidoxime methylsulphate in the treatment of the organophosphate poisoning
    • Willems J.L. Cholinesterase reactivation in organophosphorus poisoned patients depends on the plasma concentration of the oxime pralidoxime methylsulphate in the treatment of the organophosphate poisoning. Arch. Toxicol. 67:1993;79-84.
    • (1993) Arch. Toxicol. , vol.67 , pp. 79-84
    • Willems, J.L.1
  • 19
    • 0344071092 scopus 로고    scopus 로고
    • Pralidoxime methylsulfate in the treatment of organophosphorus poisoning
    • L. Szinicz, P. Eyer, & R. Klimmek. Heidelberg: Spektrum
    • Willems J.L. Pralidoxime methylsulfate in the treatment of organophosphorus poisoning. Szinicz L., Eyer P., Klimmek R. Role of Oximes in the Treatment of Anticholinesterase Agent Poisoning. 1996;69-73 Spektrum, Heidelberg.
    • (1996) Role of Oximes in the Treatment of Anticholinesterase Agent Poisoning , pp. 69-73
    • Willems, J.L.1
  • 21
    • 0032892487 scopus 로고    scopus 로고
    • Dimethylphosphoryl-inhibited human cholinesterases: Inhibition, reactivation, and aging kinetics
    • Worek, F., Diepold, C., Eyer, P., 1999. Dimethylphosphoryl-inhibited human cholinesterases: inhibition, reactivation, and aging kinetics. Arch. Toxicol. 73, 7-14.
    • (1999) Arch. Toxicol. , vol.73 , pp. 7-14
    • Worek, F.1    Diepold, C.2    Eyer, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.