Kinetic analysis of interactions of paraoxon and oximes with human, Rhesus monkey, swine, rabbit, rat and guinea pig acetylcholinesterase

Toxicology Letters

Volumn 200, Issue 1-2, 2011, Pages 19-23

  Worek, Franz ^a   Aurbek, Nadine ^a   Wille, Timo ^a   Eyer, Peter ^b   Thiermann, Horst ^a  

^a BUNDESWEHR INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY   (Germany)

^b UNIVERSITY OF MUNICH   (Germany)

Author keywords

Acetylcholinesterase; Kinetics; Organophosphorus compound; Oximes; Paraoxon; Species differences

Indexed keywords

1 (4 CARBAMOYLPYRIDINIO) 1' (2 HYDROXYIMINOMETHYLPYRIDINIO)DIMETHYL ETHER; 1,1' METHYLENEBIS(4 HYDROXYIMINOMETHYLPYRIDINIUM) DICHLORIDE; ACETYLCHOLINESTERASE; OBIDOXIME; PARAOXON; PRALIDOXIME;

AGING; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME INHIBITION; ENZYME REACTIVATION; ERYTHROCYTE; EXPERIMENTAL GUINEA PIG; EXPERIMENTAL PIG; EXPERIMENTAL RABBIT; HUMAN; HUMAN CELL; HUMAN VERSUS ANIMAL COMPARISON; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; RAT; RHESUS MONKEY; TOXICOKINETICS;

ACETYLCHOLINESTERASE; ANIMALS; CHOLINESTERASE INHIBITORS; DRUG INTERACTIONS; ENZYME REACTIVATORS; GUINEA PIGS; HUMANS; KINETICS; MACACA MULATTA; OBIDOXIME CHLORIDE; OXIMES; PARAOXON; PRALIDOXIME COMPOUNDS; PYRIDINIUM COMPOUNDS; RABBITS; RATS; RATS, WISTAR; SPECIES SPECIFICITY; SWINE;

ANIMALIA; CAVIA; MACACA MULATTA; ORYCTOLAGUS CUNICULUS; RATTUS; SUIDAE;

EID: 78650176292     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2010.10.009     Document Type: Article

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