Glutathione regulates caspase-dependent ceramide production and curcumin-induced apoptosis in human leukemic cells

Free Radical Biology and Medicine

Volumn 52, Issue 9, 2012, Pages 1854-1864

  Kizhakkayil, Jaleel ^a   Thayyullathil, Faisal ^a   Chathoth, Shahanas ^a   Hago, Abdulkader ^a   Patel, Mahendra ^a   Galadari, Sehamuddin ^a  

^a UNITED ARAB EMIRATES UNIVERSITY   (United Arab Emirates)

Author keywords

Apoptosis; Caspase 3; Ceramide; Curcumin; Free radicals; Glutathione; Sphingomyelin synthase

Indexed keywords

BUTHIONINE SULFOXIMINE; CARBOBENZOXY VALYLALANYLASPARTIC ACID FLUOROMETHYLKETONE; CASPASE; CASPASE INHIBITOR; CERAMIDE; CURCUMIN; CYCLIN D1; GLUTATHIONE; INHIBITOR OF APOPTOSIS PROTEIN; MYC PROTEIN; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; SPHINGOMYELIN; SPHINGOMYELIN SYNTHASE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL LINE; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME INHIBITION; GROWTH INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; LEUKEMIA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION;

AMINO ACID CHLOROMETHYL KETONES; APOPTOSIS; BLOTTING, WESTERN; CASPASES; CELL LINE; CERAMIDES; CURCUMIN; GLUTATHIONE; HUMANS; LEUKEMIA;

INTRACISTERNAL A-PARTICLES;

EID: 84859150636     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2012.02.026     Document Type: Article

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