Increase of Nuclear Ceramide through Caspase-3-Dependent Regulation of the "Sphingomyelin Cycle" in Fas-Induced Apoptosis

Cancer Research

Volumn 64, Issue 3, 2004, Pages 1000-1007

  Watanabe, Mitsumasa ^a   Kitano, Toshiyuki ^a   Kondo, Tadakazu ^a   Yabu, Takeshi ^a   Taguchi, Yoshimitsu ^a   Tashima, Masaro ^a   Umehara, Hisanori ^a   Domae, Naochika ^b   Uchiyama, Takashi ^a   Okazaki, Toshiro ^a  

^a KYOTO UNIVERSITY   (Japan)

^b OSAKA DENTAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLASPARTYLGLUTAMYLVALYLASPARTYL CHLOROMETHYL KETONE; ANTIBODY; CASPASE 3; CERAMIDE; CERAMIDE ANTIBODY; FAS ANTIGEN; KETONE; SPHINGOMYELIN; SPHINGOMYELIN PHOSPHODIESTERASE; SPHINGOMYELIN SYNTHASE; TRICYCLO[4.3.0.1]DECAN 9 YL XANTHOGENATE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL FRACTIONATION; CELL LYSATE; CELL NUCLEUS; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CROSS LINKING; DOSE TIME EFFECT RELATION; ENZYME ACTIVATION; ENZYME ASSAY; ENZYME INHIBITION; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; MICROSOME; PRIORITY JOURNAL; REGULATORY MECHANISM; STRESS;

AMINO ACID CHLOROMETHYL KETONES; ANTIGENS, CD95; APOPTOSIS; BRIDGED COMPOUNDS; CASPASE 3; CASPASES; CELL NUCLEUS; CERAMIDES; CYSTEINE PROTEINASE INHIBITORS; ENZYME ACTIVATION; HUMANS; JURKAT CELLS; PHOSPHODIESTERASE INHIBITORS; SPHINGOMYELIN PHOSPHODIESTERASE; SPHINGOMYELINS; T-LYMPHOCYTES; THIONES; TRANSFERASES (OTHER SUBSTITUTED PHOSPHATE GROUPS);

EID: 10744227465     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-03-1383     Document Type: Article

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