Modulation of curcumin-induced Akt phosphorylation and apoptosis by PI3K inhibitor in MCF-7 cells

Biochemical and Biophysical Research Communications

Volumn 394, Issue 3, 2010, Pages 476-481

  Kizhakkayil, Jaleel ^a   Thayyullathil, Faisal ^a   Chathoth, Shahanas ^a   Hago, Abdulkader ^a   Patel, Mahendra ^a   Galadari, Sehamuddin ^a  

^a UNITED ARAB EMIRATES UNIVERSITY   (United Arab Emirates)

Author keywords

Akt phosphorylation; Apoptosis; Curcumin; MCF 7 cells; PI3K inhibitor

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; CURCUMIN; GLYCOGEN SYNTHASE KINASE 3BETA; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN KINASE B; PROTEIN SERINE THREONINE KINASE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL STRAIN MCF 7; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG POTENTIATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANTINEOPLASTIC AGENTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CELL LINE, TUMOR; CELL SURVIVAL; CHROMONES; CURCUMIN; GLYCOGEN SYNTHASE KINASE 3; HUMANS; MORPHOLINES; PHOSPHORYLATION; POLY(ADP-RIBOSE) POLYMERASES; PROTO-ONCOGENE PROTEINS C-AKT; TUMOR SUPPRESSOR PROTEIN P53;

EID: 77950516392     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2010.01.132     Document Type: Article

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