Effect of central and peripheral cholinergic antagonists on chlorpyrifos-induced changes in body temperature in the rat

Toxicology

Volumn 142, Issue 1, 1999, Pages 15-28

  Gordon, Christopher J ^a   Grantham, Tholeathcus A ^a  

^a U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

Anticholinesterase; Fever; Hypothermia; Methyl scopolamine; Organophosphate; Pesticide; Scopolamine

Indexed keywords

CHLORPYRIFOS; METHYLSCOPOLAMINE; PESTICIDE; SCOPOLAMINE;

ANIMAL EXPERIMENT; ARTICLE; CHOLINERGIC STIMULATION; CHOLINERGIC SYSTEM; CONTROLLED STUDY; CORE TEMPERATURE; ENVIRONMENTAL EXPOSURE; FEMALE; HEAT LOSS; HYPOTHERMIA; INTRAPERITONEAL DRUG ADMINISTRATION; MOTOR ACTIVITY; NONHUMAN; PRIORITY JOURNAL; RAT; THERMOGENESIS; THERMOREGULATION;

ANIMALS; BODY TEMPERATURE; CHLORPYRIFOS; CHOLINERGIC FIBERS; CHOLINESTERASE INHIBITORS; FEMALE; FEVER; HYPOTHERMIA; INSECTICIDES; MUSCARINIC ANTAGONISTS; N-METHYLSCOPOLAMINE; RATS; RATS, LONG-EVANS; SCOPOLAMINE;

CHANDIPURA VIRUS; ZEA MAYS;

EID: 0032730449     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0300-483X(99)00121-3     Document Type: Article

References (27)

1. Aspelin, A., June 1994. Pesticides industry sales and usage-1992 and 1993 market estimates. U.S. Environmental Protection Agency, report no. 733-K-94-001.
2. Ballantyne B., Marrs T.C. Overview of the biological and clinical aspects of organophosphates and carbamates. Ballantyne B., Marrs T.C. Clinical and experimental toxicology of organophosphates and carbamates. 1992;3-14 Butterworth-Heinemann, Oxford.
3. Blatteis C.M., Sehic E. Fever: How may circulating pyrogens signal the brain? News Physiol. Sci. 12:1997;1-9.
4. Bligh J. Mammalian homeothermy: an integrative thesis. J. Thermal Biol. 23:1989;143-258.
5. Gordon C.J. Temperature Regulation in Laboratory Rodents. 1993;Cambridge University Press, New York.
6. Gordon C.J. 24-hour control of body temperature in the rat: II. Diisopropyl fluorophosphate-induced hypothermia and hyperthermia. Pharm. Bioch. Behav. 49:1994;747-754.
7. Gordon C.J. Thermoregulatory effects of chlorpyrifos in the rat: long-term changes in cholinergic and noradrenergic sensitivity. Neurotoxicol. Terat. 16:1994;1-9.
8. Gordon C.J. Pharmacological analysis of diisopropyl fluorophosphate: effects on core temperature, heart rate and motor activity in the unrestrained rat. Pharm. Biochem. Behav. 55:1996;185-194.
9. Gordon C.J., Grantham T., Yang Y. Hypothermia and delayed fever in the male and female rat exposed to chlorpyrifos. Toxicology. 118:1997;149-158.
10. Gordon C.J. Behavioral thermoregulatory response to chlorpyrifos in the rat. Toxicology. 124:1997;165-171.
11. Gordon, C.J., Rowsey, P.J., 1999. Role of vagal afferents in the mediation of chlorpyrifos-induced fever in the rat. J. Therm. Biol. (in press).
12. Hellon R.F. Monoamines pyrogens and cations: Their actions on central control of body temperature. Pharmacol. Rev. 26:1975;289-320.
13. Kluger M.J. Fever: role of pyrogens and cryogens. Physiol. Rev. 71:1991;93-127.
14. Lipton J.M., Clark W.G. Neurotransmitters in temperature control. Annu. Rev. Physiol. 48:1986;613-623.
15. Maayani S., Egozi Y., Pinchasi I., Sokolovsky M. On the interaction of drugs with the cholinergic nervous system-V. Characterization of some effects induced by physostigmine in mice: in vivo and in vitro studies. Biochem. Pharmacol. 27:1978;203-211.
16. Maickel R.P., Kinney D.R., Ryker D.L., Nichols M.B. Antagonism of physostigmine induced hypothermia and neuroendocrine changes following exposure to different environmental temperatures. Prog. Neuro-Psychopharmacol. Biol. Psychiatry. 15:1991;873-884.
17. Meeter E. The effect of atropine on the hypothermia and the shift in set-point for heat release evoked by a cholinesterase inhibitor in the rat. Proc. R. Neth. Acad. Sci. Series C. 74:1971;105-112.
18. Moser V.C., Padilla S. Age- and gender-related differences in the time course of behavioral and biochemical effects produced by oral chlorpyrifos in rats. Toxicol. Appl. Pharmacol. 149:1998;107-119.
19. Namba T., Nolte C.T., Jackrel J., Grob D. Poisoning due to organophosphate insecticides: acute and chronic manifestations. Am. J. Med. 50:1971;475-492.
20. Nostrandt A.C., Padilla S., Moser V.C. The relationship of oral chlorpyrifos effects on behavior, cholinesterase inhibition and muscarinic receptor density in rat. Pharmacol. Biochem. Behav. 58:1997;15-23.
21. Pope C.N. Long-term neurochemical and behavioral effects induced by acute chlorpyrifos treatment. Pharmacol. Biochem. Behav. 42:1992;251-256.
22. Romanovsky A.A., Simons C.T., Szekely M., Kukchitsky V. The vagus nerve in the thermoregulatory response to systemic inflammation. Am. J. Physiol. 273:1997;R407-R413.
23. Rowsey P.J., Gordon C.J. Tolerance to the hypothermic and hyperthermic effects of chlorpyrifos. Toxicology. 121:1997;215-221.
24. Rush D.K., Streit K. Memory modulation with peripherally acting cholinergic drugs. Psychopharmacology (Berl). 106:1992;375-382.
25. Saadeh A.M., Al-Ali M.K., Farsakh N.A., Ghani M. Clinical and sociodemographic features of acute carbamate and organophosphate poisoning: a study of 70 adult patients in North Jordan. Clin. Toxicol. 34:1996;45-51.
26. Sanchez C., Lembol H.L. The involvement of muscarinic receptor subtypes in the mediation of hypothermia, tremor and salivation in male mice. Pharmacol. Toxicol. 74:1994;35-39.
27. Smith R.D., Grzelak M.E., Coffin V.L. Methylatropine blocks the central effects of cholinergic antagonists. Behav. Pharmacol. 5:1994;167-175.