The reliability of using urinary biomarkers to estimate children's exposures to chlorpyrifos and diazinon

Journal of Exposure Science and Environmental Epidemiology

Volumn 21, Issue 3, 2011, Pages 280-290

  Morgan, Marsha K ^a   Sheldon, Linda S ^a   Jones, Paul A ^a   Croghan, Carry W ^a   Chuang, Jane C ^b   Wilson, Nancy K ^b  

^a U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^b BATTELLE MEMORIAL INSTITUTE   (United States)

Author keywords

children; chlorpyrifos; diazinon; IMP; TCP

Indexed keywords

BIOLOGICAL MARKER; CHLORPYRIFOS; DIMPYLATE; INSECTICIDE;

ARTICLE; CHILD; ENVIRONMENTAL EXPOSURE; HUMAN; POLLUTANT; QUALITY CONTROL; REPRODUCIBILITY; STANDARD; UNITED STATES; URINE;

BIOLOGICAL MARKERS; CHILD; CHLORPYRIFOS; DIAZINON; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL POLLUTANTS; HUMANS; INSECTICIDES; OHIO; QUALITY CONTROL; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS;

EID: 79955117455     PISSN: 15590631     EISSN: 1559064X     Source Type: Journal    
DOI: 10.1038/jes.2010.11     Document Type: Article

References (34)

1. Adgate J.L., Barr D.B., Clayton A., Eberly L.E., Freeman N.C.G., and Lioy P.J., et al. Measurement of children's exposure to pesticides: analysis of urinary metabolite levels in probability-based sample. Environ Health Perspect 2001: 109(6): 583-590. (Pubitemid 32998770)
2. Bakke J.E., and Price C.E. Metabolism of OO-dimethyl-O-(3,5,6-trichloro- 2- pyridyl) phosphorothioate in sheep and rats and of 3,5,6-trichloro-2- pyridinol in sheep. J Environ Sci Health 1976: B11(1): 9-22.
3. Barr D.B., Wilder L.C., Caudill S.P., Gonzalez A.J., Needham L.L., and Pirkle J.L. Urinary creatinine concentrations in the U.S. Population: Implications for urinary biologic monitoring measurements. Environ Health Perspect 2005: 113(2): 192-200. (Pubitemid 40326330)
4. CDC (Centers for Disease Control and Prevention). Third national report on human exposure to environmental chemicals, 2005: http://www.cdc.gov/ exposurereport/.
5. Chuang J.C., Brinkman M., Hart K., Davis D.B., Finegold J., and Gordon S.M. Method refinement and analysis of food data, USEPA. Report to USEPA, Contract 68-D4-0023, WA 4-03. Battelle Memorial Institute, Columbus Ohio, USA, 1999.
6. Eaton D.L., Daroff R.B., Autrup H., Bridges J., Buffler P., and Costa L.G., et al. Review of the toxicology of chlorpyrifos with emphasis on human exposure and neurodevelopment. Crit Rev Toxicol 2008: 38(1): 1-125.
7. Food and Drug Administration (FDA). FDA's total diet studyFmonitoring U.S. food supply safety. http://www.fda.gov/Food/FoodSafety/ FoodContaminantsAdulteration/TotalDietStudy/ucm186140.htm, 2006.
8. Garfitt S.J., Jones K., Mason H.J., and Cocker M.J. Exposure to the organophosphate diazinon: data from a human volunteer study with oral and dermal doses. Toxicol Lett 2002: 134: 105-113. (Pubitemid 35007292)
9. Griffin P., Mason H., Heywood K., and Cocker J. Oral and dermal absorption of chlorpyrifos: a human volunteer study. Occup Environ Med 1999: 56: 10-13. (Pubitemid 29103642)
10. Hines C.J., and Deddens J.A. Determinants of chlorpyrifos exposures and urinary 3,5,6-trichloro-2-pyridinol levels among termiticide applicators. Ann Occup Hyg 2001: 45: 309-321. (Pubitemid 32506860)
11. Koch H., and Angerer J. Analysis of 3,5,6-trichloro-2-pyridinol in urine samples from the general population using gas chromatography-mass spectrometry after steam distillation and solid-phase extraction. J Chromatogr B 2001: 759: 43-49. (Pubitemid 32595435)
12. Lu C., Bravo R., Caltabiano L.M., Irish R.M., Weerasekera G., and Barr D.B. The presence of dialkylphosphates in fresh fruit juices: implications for organophosphorus pesticide exposure and risk assessments. J Toxicol Environ Health A 2005: 68(3): 209-227. (Pubitemid 40070924)
13. Miller L.A., and Stapleton F.B. Urinary volume in children with urolithiasis. J Urol 1989: 141(4): 918-920. (Pubitemid 19108676)
14. Morgan M.K., Sheldon L.S., Croghan C.W., Chuang J.C., Lordo R., andWilson N.K., et al. A pilot study of children's total exposure to persistent pesticides and other persistent organic pollutants (CTEPP). EPA/600/R-041/193. http://www.epa.gov/heasd/ctepp/ctepp-report.pdf, 2004.
15. Morgan M.K., Sheldon L.S., Croghan C.W., Jones P.A., Robertson G.L., and Chuang J.C., et al. Exposures of preschool children to chlorpyrifos and its degradation product 3,5,6-trichloro-2-pyridinol in their everyday environments. J Expo Anal Environ Epidemiol 2005: 15: 297-309. (Pubitemid 41140903)
16. Nolan R.J., Rick D.L., Freshour N.L., and Saunders J.H. Chlorpyrifos: pharmacokinetics in human volunteers. Toxicol Appl Pharmacol 1984: 73: 8-15. (Pubitemid 14131600)
17. Poet T., Kousba A., Dennison S., and Timchalk C. Physiologically based pharmacokinetic/pharmacodynamic model for the organophosphorus pesticide diazinon. Neurotoxicology 2004: 25(6): 1013-1030. (Pubitemid 39335593)
18. Racke K.D. Environmental fate of chlorpyrifos. Rev Environ Contam Toxicol 1993: 131: 1-150. (Pubitemid 23055182)
19. Raina R., and Sun L. Trace level determination of selected organophosphorus pesticides and their degradation products in environmental air samples by liquid chromatography-positive ion electrospray tandem mass spectrometry. J Environ Sci Health B 2008: 43(4): 323-332. (Pubitemid 351595247)
20. Rigas M.L., Okino M.S., and Quackenboss J.J. Use of a pharmacokinetic model to assess chlorpyrifos exposure and dose in children, based on urinary biomarker measurements. Toxicol Sci 2001: 61: 374-381. (Pubitemid 32499403)
21. Ross J.H., Driver J.H., Cockran R.C., Thongsinthusak T., and Kreiger R.I. Could pesticide toxicology studies be more relevant to occupational risk assessment? Ann Occup Hyg 2001: 45(1001): S5-S17.
22. Szabo L., and Fegyverneki S. Maximum and average urine flow rates in normal childrenFthe Miskoln nomograms. Br J Urol 1995: 76(1): 16-20.
23. Timchalk C., Busby A., Campbell J.A., Needham L.L., and Barr D.B. Comparative pharmacokinetics of the organophosphorus insecticide chlorpyrifos and its major metabolites diethylphosphate, diethythiophosphate and 3,5,6-trichloro-2-pyridinol in the rat. Toxicology 2007: 237(1-3): 145-157. (Pubitemid 47031413)
24. Timchalk C., Poet T.S., Hinman M.N., Busby A.L., and Kousba A.A. Pharmacokinetics and pharmacodynamics interaction for a binary mixture of chlorpyrifos and diazinon in the rat. Toxicol Appl Pharmacol 2005: 205(1): 31-42. (Pubitemid 40693267)
25. USEPA. Chlorpyrifos-methyl, 2000: http://www.epa.gov/oppsrrd1/ reregistration/chlorpyrifos-methyl/.
26. USEPA. Chlorpyrifos facts, 2002: http://www.epa.gov/oppsrrd1/REDs/ factsheets/chlorpyrifos-fs.htm.
27. USEPA. Diazinon, 2008: http://www.epa.gov/opp00001/reregistration/ diazinon/.
28. Weerasekera G., Smith K.D., Quiros-Alcala L., Fernandez C., Bradman A., Eskenazi B., Needham L.L., and Barr D.B. A mass spectrometry-based method to measure dialkylphosphate degradation products of organophosphorous insecticides in dust and orange juice. J Environ Monit 2009: 11: 1345-1351.
29. Wilson N.K., Chuang J.C., Iachan R., Lyu C., Gordon S.M., and Morgan M.K., et al. Design and sampling methodology for a large study of preschool children's aggregate exposures to persistent organic pollutants in their everyday environments. J Expo Anal Environ Epidemiol 2004: 14: 260-274. (Pubitemid 38765949)
30. Wilson N.K., Chuang J.C., and Lyu C. Levels of persistent organic pollutants in several child day care centers. J Expo Anal Environ Epidemiol 2001: 11: 449-458. (Pubitemid 34024792)
31. Wilson N.K., Chuang J.C., Lyu C., Menton R., and Morgan M.K. Aggregate exposures of nine preschool children to persistent organic pollutants at daycare and at home. J Expo Anal Environ Epidemiol 2003: 13(1): 187-202. (Pubitemid 36753834)
32. Wilson N.K., Chuang J.C., Strauss W., Lyu C., Iroz-Elardo N., and Pivetz T. Pesticide Exposures of Preschool Children Over Time (PEPCOT), National Center for Environmental Research, Washington DC. Final Report, STAR Grant R829363 2008.
33. Wilson N.K., Strauss W.J., Iroz-Elardo N., and Chuang J.C. Exposures of preschool children to chlorpyrifos, diazinon, pentachlorophenol, and 2,4- diphenoxyacetic acid over 3 years from 2003 to 2005: A longitudinal model. J Expo Sci Environ Epidemiol 2009 (advance online publication, 2 September 2009; doi:10.1038/jes.2009.45).
34. Zhang X., Driver J.H., Li Y., Ross J.H., and Kreiger R.I. Dialklphosphate (DAPs) in fruits and vegetables may confound biomonitoring in organophosphorus insecticide exposure and risk assessment. J Agric Food Chem 2008: 56: 10638-10645.