Mechanism-based inactivation of cytochrome P450 2B1 by 8- methoxypsoralen and several other furanocoumarins

Biochemistry

Volumn 37, Issue 38, 1998, Pages 13184-13193

  Koenigs, Luke L ^a   Trager, William F ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FUROCOUMARIN DERIVATIVE; METHOXSALEN; PENTOXYRESORUFIN DEALKYLASE; REACTIVE OXYGEN METABOLITE;

ARTICLE; COVALENT BOND; ENZYME INACTIVATION; LIQUID CHROMATOGRAPHY; LIQUID SCINTILLATION COUNTING; OXIDATION; PRIORITY JOURNAL; TANDEM MASS SPECTROMETRY;

ANIMALS; BINDING SITES; CHROMATOGRAPHY, LIQUID; COUMARINS; CYTOCHROME P-450 CYP2B1; ENZYME ACTIVATION; ENZYME INHIBITORS; FICUSIN; MALE; MASS SPECTROMETRY; METHOXSALEN; MICROSOMES, LIVER; NADP; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0032558386     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi981198r     Document Type: Article

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