메뉴 건너뛰기




Volumn 123, Issue 5, 2012, Pages 902-909

Chronic treatment with rivastigmine in patients with Alzheimer's disease: A study on primary motor cortex excitability tested by 5Hz-repetitive transcranial magnetic stimulation

Author keywords

Alzheimer's disease (AD); Cholinesterase inhibitor; Repetitive transcranial magnetic stimulation (rTMS); Synaptic plasticity

Indexed keywords

RIVASTIGMINE;

EID: 84858751070     PISSN: 13882457     EISSN: 18728952     Source Type: Journal    
DOI: 10.1016/j.clinph.2011.09.010     Document Type: Article
Times cited : (22)

References (109)
  • 1
    • 0035856385 scopus 로고    scopus 로고
    • Transcranial magnetic stimulation in Alzheimer disease: motor cortex excitability and cognitive severity
    • Alagona G., Bella R., Ferri R., Carnemolla A., Pappalardo A., Costanzo E., et al. Transcranial magnetic stimulation in Alzheimer disease: motor cortex excitability and cognitive severity. Neurosci Lett 2001, 314:57-60.
    • (2001) Neurosci Lett , vol.314 , pp. 57-60
    • Alagona, G.1    Bella, R.2    Ferri, R.3    Carnemolla, A.4    Pappalardo, A.5    Costanzo, E.6
  • 2
    • 0023943181 scopus 로고
    • Differential alteration of various cholinergic markers in cortical and subcortical regions of human brain in Alzheimer's disease
    • Araujo D.M., Lapchak P.A., Robitaille Y., Gauthier S., Quirion R. Differential alteration of various cholinergic markers in cortical and subcortical regions of human brain in Alzheimer's disease. J Neurochem 1988, 50:1914-1923.
    • (1988) J Neurochem , vol.50 , pp. 1914-1923
    • Araujo, D.M.1    Lapchak, P.A.2    Robitaille, Y.3    Gauthier, S.4    Quirion, R.5
  • 3
    • 0037130594 scopus 로고    scopus 로고
    • Rivastigmine antagonizes deficits in prepulse inhibition induced by selective immunolesioning of cholinergic neurons in nucleus basalis magnocellularis
    • Ballmaier M., Casamenti F., Scali C., Mazzoncini R., Zoli M., Pepeu G., et al. Rivastigmine antagonizes deficits in prepulse inhibition induced by selective immunolesioning of cholinergic neurons in nucleus basalis magnocellularis. Neuroscience 2002, 114:91-98.
    • (2002) Neuroscience , vol.114 , pp. 91-98
    • Ballmaier, M.1    Casamenti, F.2    Scali, C.3    Mazzoncini, R.4    Zoli, M.5    Pepeu, G.6
  • 6
    • 0027243377 scopus 로고
    • Neocortical long-term potentiation
    • Bear M.F., Kirkwood A. Neocortical long-term potentiation. Curr Opin Neurobiol 1993, 3:197-202.
    • (1993) Curr Opin Neurobiol , vol.3 , pp. 197-202
    • Bear, M.F.1    Kirkwood, A.2
  • 7
  • 8
    • 0025081430 scopus 로고
    • Cholinergic stimulation enhances long-term potentiation in the CA1 region of rat hippocampus
    • Blitzer R.D., Gil O., Landau E.M. Cholinergic stimulation enhances long-term potentiation in the CA1 region of rat hippocampus. Neurosci Lett 1990, 119:207-210.
    • (1990) Neurosci Lett , vol.119 , pp. 207-210
    • Blitzer, R.D.1    Gil, O.2    Landau, E.M.3
  • 9
    • 0029553116 scopus 로고
    • Acetylcholine: a neurotransmitter for learning and memory?
    • Blokland A. Acetylcholine: a neurotransmitter for learning and memory?. Brain Res Brain Res Rev 1995, 21:285-300.
    • (1995) Brain Res Brain Res Rev , vol.21 , pp. 285-300
    • Blokland, A.1
  • 10
    • 0442291763 scopus 로고    scopus 로고
    • Efficacy and safety of donepezil in patients with Alzheimer's disease: results of a global, multinational, clinical experience study
    • Boada-Rovira M., Brodaty H., Cras P., Baloyannis S., Emre M., Zhang R., et al. Efficacy and safety of donepezil in patients with Alzheimer's disease: results of a global, multinational, clinical experience study. Drugs Aging 2004, 21:43-53.
    • (2004) Drugs Aging , vol.21 , pp. 43-53
    • Boada-Rovira, M.1    Brodaty, H.2    Cras, P.3    Baloyannis, S.4    Emre, M.5    Zhang, R.6
  • 11
    • 0026595138 scopus 로고
    • Agonists of cholinergic and noradrenergic receptors facilitate synergistically the induction of long-term potentiation in slices of rat visual cortex
    • Bröcher S., Artola A., Singer W. Agonists of cholinergic and noradrenergic receptors facilitate synergistically the induction of long-term potentiation in slices of rat visual cortex. Brain Res 1992, 573:27-36.
    • (1992) Brain Res , vol.573 , pp. 27-36
    • Bröcher, S.1    Artola, A.2    Singer, W.3
  • 12
    • 0034728596 scopus 로고    scopus 로고
    • Quantitative assessment of nicotinic acetylcholine receptor proteins in the cerebral cortex of Alzheimer patients
    • Burghaus L., Schütz U., Krempel U., de Vos R.A., Jansen Steur E.N., Wevers A., et al. Quantitative assessment of nicotinic acetylcholine receptor proteins in the cerebral cortex of Alzheimer patients. Brain Res Mol Brain Res 2000, 76:385-388.
    • (2000) Brain Res Mol Brain Res , vol.76 , pp. 385-388
    • Burghaus, L.1    Schütz, U.2    Krempel, U.3    de Vos, R.A.4    Jansen Steur, E.N.5    Wevers, A.6
  • 14
    • 0034069795 scopus 로고    scopus 로고
    • Impairment of hippocampal long-term potentiation by Alzheimer amyloid beta-peptides
    • Chen Q.S., Kagan B.L., Hirakura Y., Xie C.W. Impairment of hippocampal long-term potentiation by Alzheimer amyloid beta-peptides. J Neurosci Res 2000, 60:65-72.
    • (2000) J Neurosci Res , vol.60 , pp. 65-72
    • Chen, Q.S.1    Kagan, B.L.2    Hirakura, Y.3    Xie, C.W.4
  • 15
    • 77953892400 scopus 로고    scopus 로고
    • Molecular mechanisms of neurodegeneration in Alzheimer's disease
    • Crews L., Masliah E. Molecular mechanisms of neurodegeneration in Alzheimer's disease. Hum Mol Genet 2010, 19:R12-R20.
    • (2010) Hum Mol Genet , vol.19
    • Crews, L.1    Masliah, E.2
  • 16
    • 77956843852 scopus 로고    scopus 로고
    • Increased BMP6 levels in the brains of Alzheimer's disease patients and APP transgenic mice are accompanied by impaired neurogenesis
    • Crews L., Adame A., Patrick C., Delaney A., Pham E., Rockenstein E., et al. Increased BMP6 levels in the brains of Alzheimer's disease patients and APP transgenic mice are accompanied by impaired neurogenesis. J Neurosci 2010, 30:12252-12262.
    • (2010) J Neurosci , vol.30 , pp. 12252-12262
    • Crews, L.1    Adame, A.2    Patrick, C.3    Delaney, A.4    Pham, E.5    Rockenstein, E.6
  • 17
    • 0030809128 scopus 로고    scopus 로고
    • Block of LTP in rat hippocampus in vivo by beta-amyloid precursor protein fragments
    • Cullen W.K., Suh Y.H., Anwyl R., Rowan M.J. Block of LTP in rat hippocampus in vivo by beta-amyloid precursor protein fragments. Neuroreport 1997, 8:3213-3217.
    • (1997) Neuroreport , vol.8 , pp. 3213-3217
    • Cullen, W.K.1    Suh, Y.H.2    Anwyl, R.3    Rowan, M.J.4
  • 18
  • 19
    • 0011162190 scopus 로고
    • Selective loss of central cholinergic neurons in Alzheimer's disease
    • Davies P., Maloney A.J. Selective loss of central cholinergic neurons in Alzheimer's disease. Lancet 1976, 2:1403.
    • (1976) Lancet , vol.2 , pp. 1403
    • Davies, P.1    Maloney, A.J.2
  • 21
    • 0037072309 scopus 로고    scopus 로고
    • Noninvasive in vivo assessment of cholinergic cortical circuits in AD using transcranial magnetic stimulation
    • Di Lazzaro V., Oliviero A., Tonali P.A., Marra C., Daniele A., Profice P., et al. Noninvasive in vivo assessment of cholinergic cortical circuits in AD using transcranial magnetic stimulation. Neurology 2002, 59:392-397.
    • (2002) Neurology , vol.59 , pp. 392-397
    • Di Lazzaro, V.1    Oliviero, A.2    Tonali, P.A.3    Marra, C.4    Daniele, A.5    Profice, P.6
  • 22
    • 0037391194 scopus 로고    scopus 로고
    • Direct demonstration of reduction of the output of the human motor cortex induced by a fatiguing muscle contraction
    • Di Lazzaro V., Oliviero A., Tonali P.A., Mazzone P., Insola A., Pilato F., et al. Direct demonstration of reduction of the output of the human motor cortex induced by a fatiguing muscle contraction. Exp Brain Res 2003, 149:535-538.
    • (2003) Exp Brain Res , vol.149 , pp. 535-538
    • Di Lazzaro, V.1    Oliviero, A.2    Tonali, P.A.3    Mazzone, P.4    Insola, A.5    Pilato, F.6
  • 23
    • 0038780798 scopus 로고    scopus 로고
    • Motor cortex hyperexcitability to transcranial magnetic stimulation in Alzheimer's disease: evidence of impaired glutamatergic neurotransmission?
    • Di Lazzaro V., Oliviero A., Pilato F., Saturno E., Dileone M., Tonali P.A. Motor cortex hyperexcitability to transcranial magnetic stimulation in Alzheimer's disease: evidence of impaired glutamatergic neurotransmission?. Ann Neurol 2003, 53(824):824-825.
    • (2003) Ann Neurol , vol.53 , Issue.824 , pp. 824-825
    • Di Lazzaro, V.1    Oliviero, A.2    Pilato, F.3    Saturno, E.4    Dileone, M.5    Tonali, P.A.6
  • 25
    • 0027512094 scopus 로고
    • Pairing the cholinergic agonist carbachol with patterned Schaffer collateral stimulation initiates protein synthesis in hippocampal CA1 pyramidal cell dendrites via a muscarinic, NMDA-dependent mechanism
    • Feig S., Lipton P. Pairing the cholinergic agonist carbachol with patterned Schaffer collateral stimulation initiates protein synthesis in hippocampal CA1 pyramidal cell dendrites via a muscarinic, NMDA-dependent mechanism. J Neurosci 1993, 13:1010-1021.
    • (1993) J Neurosci , vol.13 , pp. 1010-1021
    • Feig, S.1    Lipton, P.2
  • 26
    • 77955894755 scopus 로고    scopus 로고
    • The muscarinic long-term enhancement of NMDA and AMPA receptor-mediated transmission at Schaffer collateral synapses develop through different intracellular mechanisms
    • Fernández de Sevilla D., Buño W. The muscarinic long-term enhancement of NMDA and AMPA receptor-mediated transmission at Schaffer collateral synapses develop through different intracellular mechanisms. J Neurosci 2010, 30:11032-11042.
    • (2010) J Neurosci , vol.30 , pp. 11032-11042
    • Fernández de Sevilla, D.1    Buño, W.2
  • 27
    • 0037231771 scopus 로고    scopus 로고
    • Motor cortex excitability in Alzheimer's disease: a transcranial magnetic stimulation study
    • Ferreri F., Pauri F., Pasqualetti P., Fini R., Dal Forno G., Rossini P.M. Motor cortex excitability in Alzheimer's disease: a transcranial magnetic stimulation study. Ann Neurol 2003, 53:102-108.
    • (2003) Ann Neurol , vol.53 , pp. 102-108
    • Ferreri, F.1    Pauri, F.2    Pasqualetti, P.3    Fini, R.4    Dal Forno, G.5    Rossini, P.M.6
  • 28
    • 79952068849 scopus 로고    scopus 로고
    • Motor cortex excitability in Alzheimer's disease: a transcranial magnetic stimulation follow-up study
    • Ferreri F., Pasqualetti P., Määttä S., Ponzo D., Guerra A., Bressi F., et al. Motor cortex excitability in Alzheimer's disease: a transcranial magnetic stimulation follow-up study. Neurosci Lett 2011, 492:94-98.
    • (2011) Neurosci Lett , vol.492 , pp. 94-98
    • Ferreri, F.1    Pasqualetti, P.2    Määttä, S.3    Ponzo, D.4    Guerra, A.5    Bressi, F.6
  • 29
    • 0027269660 scopus 로고
    • Cortical pyramidal neurone loss may cause glutamatergic hypoactivity and cognitive impairment in Alzheimer's disease: investigative and therapeutic perspectives
    • Francis P.T., Sims N.R., Procter A.W., Bowen D.M. Cortical pyramidal neurone loss may cause glutamatergic hypoactivity and cognitive impairment in Alzheimer's disease: investigative and therapeutic perspectives. J Neurochem 1993, 60:1589-1604.
    • (1993) J Neurochem , vol.60 , pp. 1589-1604
    • Francis, P.T.1    Sims, N.R.2    Procter, A.W.3    Bowen, D.M.4
  • 30
    • 0035128734 scopus 로고    scopus 로고
    • Blockade of long-term potentiation by beta-amyloid peptides in the CA1 region of the rat hippocampus in vivo
    • Freir D.B., Holscher C., Herron C.E. Blockade of long-term potentiation by beta-amyloid peptides in the CA1 region of the rat hippocampus in vivo. J Neurophysiol 2001, 85:708-713.
    • (2001) J Neurophysiol , vol.85 , pp. 708-713
    • Freir, D.B.1    Holscher, C.2    Herron, C.E.3
  • 31
    • 0041423730 scopus 로고    scopus 로고
    • Interneuron diversity series: rhythm and mood in perisomatic inhibition
    • Freund T.F. Interneuron diversity series: rhythm and mood in perisomatic inhibition. Trends Neurosci 2003, 26:489-495.
    • (2003) Trends Neurosci , vol.26 , pp. 489-495
    • Freund, T.F.1
  • 32
    • 0016823810 scopus 로고
    • "Mini-mental state" A practical method for grading the cognitive state of patients for the clinician
    • Folstein M.F., Folstein S.E., McHugh P.R. "Mini-mental state" A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 1975, 12:189-198.
    • (1975) J Psychiatr Res , vol.12 , pp. 189-198
    • Folstein, M.F.1    Folstein, S.E.2    McHugh, P.R.3
  • 33
    • 0032852717 scopus 로고    scopus 로고
    • Acute and chronic nicotine exposure differentially facilitate the induction of LTP
    • Fujii S., Ji Z., Morita N., Sumikawa K. Acute and chronic nicotine exposure differentially facilitate the induction of LTP. Brain Res 1999, 846:137-143.
    • (1999) Brain Res , vol.846 , pp. 137-143
    • Fujii, S.1    Ji, Z.2    Morita, N.3    Sumikawa, K.4
  • 34
    • 33847787591 scopus 로고    scopus 로고
    • Oligomeric amyloid decreases basal levels of brain-derived neurotrophic factor (BDNF) mRNA via specific downregulation of BDNF transcripts IV and V in differentiated human neuroblastoma cells
    • Garzon D.J., Fahnestock M. Oligomeric amyloid decreases basal levels of brain-derived neurotrophic factor (BDNF) mRNA via specific downregulation of BDNF transcripts IV and V in differentiated human neuroblastoma cells. J Neurosci 2007, 27:2628-2635.
    • (2007) J Neurosci , vol.27 , pp. 2628-2635
    • Garzon, D.J.1    Fahnestock, M.2
  • 35
    • 42749084885 scopus 로고    scopus 로고
    • Asymmetric responses to repetitive transcranial magnetic stimulation (rTMS) over the left and right primary motor cortex in a patient with lateralized progressive limb-kinetic apraxia
    • Gilio F., Iacovelli E., Conte A., Frasca V., Gabriele M., Giacomelli E., et al. Asymmetric responses to repetitive transcranial magnetic stimulation (rTMS) over the left and right primary motor cortex in a patient with lateralized progressive limb-kinetic apraxia. Neurosci Lett 2008, 437:125-129.
    • (2008) Neurosci Lett , vol.437 , pp. 125-129
    • Gilio, F.1    Iacovelli, E.2    Conte, A.3    Frasca, V.4    Gabriele, M.5    Giacomelli, E.6
  • 36
    • 0031596277 scopus 로고    scopus 로고
    • Perspectives in clinical Alzheimer's disease research and the development of antidementia drugs
    • Grundman M., Corey-Bloom J., Thal L.J. Perspectives in clinical Alzheimer's disease research and the development of antidementia drugs. J Neural Transm Suppl 1998, 53:255-275.
    • (1998) J Neural Transm Suppl , vol.53 , pp. 255-275
    • Grundman, M.1    Corey-Bloom, J.2    Thal, L.J.3
  • 37
    • 0033983966 scopus 로고    scopus 로고
    • Decreased protein levels of nicotinic receptor subunits in the hippocampus and temporal cortex of patients with Alzheimer's disease
    • Guan Z.Z., Zhang X., Ravid R., Nordberg A. Decreased protein levels of nicotinic receptor subunits in the hippocampus and temporal cortex of patients with Alzheimer's disease. J Neurochem 2000, 74:237-243.
    • (2000) J Neurochem , vol.74 , pp. 237-243
    • Guan, Z.Z.1    Zhang, X.2    Ravid, R.3    Nordberg, A.4
  • 39
    • 0028876358 scopus 로고
    • Cholinergic modulation of activity-dependent synaptic plasticity in the piriform cortex and associative memory function in a network biophysical simulation
    • Hasselmo M.E., Barkai E. Cholinergic modulation of activity-dependent synaptic plasticity in the piriform cortex and associative memory function in a network biophysical simulation. J Neurosci 1995, 15:6592-6604.
    • (1995) J Neurosci , vol.15 , pp. 6592-6604
    • Hasselmo, M.E.1    Barkai, E.2
  • 40
    • 0037080322 scopus 로고    scopus 로고
    • Prefrontal cortex long-term potentiation, but not long-term depression, is associated with the maintenance of extinction of learned fear in mice
    • Herry C., Garcia R. Prefrontal cortex long-term potentiation, but not long-term depression, is associated with the maintenance of extinction of learned fear in mice. J Neurosci 2002, 22:577-583.
    • (2002) J Neurosci , vol.22 , pp. 577-583
    • Herry, C.1    Garcia, R.2
  • 41
    • 0029926302 scopus 로고    scopus 로고
    • Long-term potentiation and long-term depression of horizontal connections in rat motor cortex
    • Hess G., Donoghue J.P. Long-term potentiation and long-term depression of horizontal connections in rat motor cortex. Acta Neurobiol Exp (Wars) 1996, 56:397-405.
    • (1996) Acta Neurobiol Exp (Wars) , vol.56 , pp. 397-405
    • Hess, G.1    Donoghue, J.P.2
  • 42
    • 0033623829 scopus 로고    scopus 로고
    • Density and pharmacology of alpha5 subunit-containing GABA(A) receptors are preserved in hippocampus of Alzheimer's disease patients
    • Howell O., Atack J.R., Dewar D., McKernan R.M., Sur C. Density and pharmacology of alpha5 subunit-containing GABA(A) receptors are preserved in hippocampus of Alzheimer's disease patients. Neuroscience 2000, 98:669-675.
    • (2000) Neuroscience , vol.98 , pp. 669-675
    • Howell, O.1    Atack, J.R.2    Dewar, D.3    McKernan, R.M.4    Sur, C.5
  • 43
    • 0037354504 scopus 로고    scopus 로고
    • Quantitation of alternatively spliced NMDA receptor NR1 isoform mRNA transcripts in human brain by competitive RT-PCR
    • Hynd M.R., Scott H.L., Dodd P.R. Quantitation of alternatively spliced NMDA receptor NR1 isoform mRNA transcripts in human brain by competitive RT-PCR. Brain Res Brain Res Protoc 2003, 11:52-66.
    • (2003) Brain Res Brain Res Protoc , vol.11 , pp. 52-66
    • Hynd, M.R.1    Scott, H.L.2    Dodd, P.R.3
  • 44
    • 0037112547 scopus 로고    scopus 로고
    • Short-interval paired-pulse inhibition and facilitation of human motor cortex: the dimension of stimulus intensity
    • Ilić T.V., Meintzschel F., Cleff U., Ruge D., Kessler K.R., Ziemann U. Short-interval paired-pulse inhibition and facilitation of human motor cortex: the dimension of stimulus intensity. J Physiol 2002, 545:153-167.
    • (2002) J Physiol , vol.545 , pp. 153-167
    • Ilić, T.V.1    Meintzschel, F.2    Cleff, U.3    Ruge, D.4    Kessler, K.R.5    Ziemann, U.6
  • 45
    • 0027177859 scopus 로고
    • Silent period evoked by transcranial stimulation of the human cortex and cervicomedullary junction
    • Inghilleri M., Berardelli A., Cruccu G., Manfredi M. Silent period evoked by transcranial stimulation of the human cortex and cervicomedullary junction. J Physiol 1993, 466:521-534.
    • (1993) J Physiol , vol.466 , pp. 521-534
    • Inghilleri, M.1    Berardelli, A.2    Cruccu, G.3    Manfredi, M.4
  • 46
    • 1442286469 scopus 로고    scopus 로고
    • Antiepileptic drugs and cortical excitability: a study with repetitive transcranial stimulation
    • Inghilleri M., Conte A., Frasca V., Curra' A., Gilio F., Manfredi M., et al. Antiepileptic drugs and cortical excitability: a study with repetitive transcranial stimulation. Exp Brain Res 2004, 154:488-493.
    • (2004) Exp Brain Res , vol.154 , pp. 488-493
    • Inghilleri, M.1    Conte, A.2    Frasca, V.3    Curra', A.4    Gilio, F.5    Manfredi, M.6
  • 49
    • 0034879826 scopus 로고    scopus 로고
    • Timing and location of nicotinic activity enhances or depresses hippocampal synaptic plasticity
    • Ji D., Lape R., Dani J.A. Timing and location of nicotinic activity enhances or depresses hippocampal synaptic plasticity. Neuron 2001, 31:131-141.
    • (2001) Neuron , vol.31 , pp. 131-141
    • Ji, D.1    Lape, R.2    Dani, J.A.3
  • 51
    • 0035866076 scopus 로고    scopus 로고
    • Use-dependent effects of amyloidogenic fragments of (beta)-amyloid precursor protein on synaptic plasticity in rat hippocampus in vivo
    • Kim J.H., Anwyl R., Suh Y.H., Djamgoz M.B., Rowan M.J. Use-dependent effects of amyloidogenic fragments of (beta)-amyloid precursor protein on synaptic plasticity in rat hippocampus in vivo. J Neurosci 2001, 21:1327-1333.
    • (2001) J Neurosci , vol.21 , pp. 1327-1333
    • Kim, J.H.1    Anwyl, R.2    Suh, Y.H.3    Djamgoz, M.B.4    Rowan, M.J.5
  • 52
    • 0035297712 scopus 로고    scopus 로고
    • Targeting small Abeta oligomers: the solution to an Alzheimer's disease conundrum?
    • Klein W.L., Krafft G.A., Finch C.E. Targeting small Abeta oligomers: the solution to an Alzheimer's disease conundrum?. Trends Neurosci 2001, 24:219-224.
    • (2001) Trends Neurosci , vol.24 , pp. 219-224
    • Klein, W.L.1    Krafft, G.A.2    Finch, C.E.3
  • 53
    • 0041349380 scopus 로고    scopus 로고
    • Transcranial magnetic stimulation in neurology
    • Kobayashi M., Pascual-Leone A. Transcranial magnetic stimulation in neurology. Lancet Neurol 2003, 2:145-156.
    • (2003) Lancet Neurol , vol.2 , pp. 145-156
    • Kobayashi, M.1    Pascual-Leone, A.2
  • 54
    • 23744508756 scopus 로고    scopus 로고
    • Modification of motor cortical excitability by an acetylcholinesterase inhibitor
    • Korchounov A., Ilic T.V., Schwinge T., Ziemann U. Modification of motor cortical excitability by an acetylcholinesterase inhibitor. Exp Brain Res 2005, 164:399-405.
    • (2005) Exp Brain Res , vol.164 , pp. 399-405
    • Korchounov, A.1    Ilic, T.V.2    Schwinge, T.3    Ziemann, U.4
  • 55
    • 77951236683 scopus 로고    scopus 로고
    • Central cholinesterase inhibition enhances glutamatergic synaptic transmission
    • Kozhemyakin M., Rajasekaran K., Kapur J. Central cholinesterase inhibition enhances glutamatergic synaptic transmission. J Neurophysiol 2010, 103:1748-1757.
    • (2010) J Neurophysiol , vol.103 , pp. 1748-1757
    • Kozhemyakin, M.1    Rajasekaran, K.2    Kapur, J.3
  • 56
    • 11544279355 scopus 로고    scopus 로고
    • Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins
    • Lambert M.P., Barlow A.K., Chromy B.A., Edwards C., Freed R., Liosatos M., et al. Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins. Proc Natl Acad Sci USA 1998, 95:6448-6453.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 6448-6453
    • Lambert, M.P.1    Barlow, A.K.2    Chromy, B.A.3    Edwards, C.4    Freed, R.5    Liosatos, M.6
  • 57
    • 3042660256 scopus 로고    scopus 로고
    • Effects of transcranial direct current stimulation over the human motor cortex on corticospinal and transcallosal excitability
    • Lang N., Nitsche M.A., Paulus W., Rothwell J.C., Lemon R.N. Effects of transcranial direct current stimulation over the human motor cortex on corticospinal and transcallosal excitability. Exp Brain Res 2004, 156:439-443.
    • (2004) Exp Brain Res , vol.156 , pp. 439-443
    • Lang, N.1    Nitsche, M.A.2    Paulus, W.3    Rothwell, J.C.4    Lemon, R.N.5
  • 58
    • 33847630793 scopus 로고    scopus 로고
    • Modulation of human motor cortex excitability by the cholinesterase inhibitor rivastigmine
    • Langguth B., Bauer E., Feix S., Landgrebe M., Binder H., Sand P., et al. Modulation of human motor cortex excitability by the cholinesterase inhibitor rivastigmine. Neurosci Lett 2007, 415:40-44.
    • (2007) Neurosci Lett , vol.415 , pp. 40-44
    • Langguth, B.1    Bauer, E.2    Feix, S.3    Landgrebe, M.4    Binder, H.5    Sand, P.6
  • 59
    • 0014579432 scopus 로고
    • Assessment of older people: self-maintaining and instrumental activities of daily living
    • Lawton M.P., Brody E.M. Assessment of older people: self-maintaining and instrumental activities of daily living. Gerontologist 1969, 9:179-186.
    • (1969) Gerontologist , vol.9 , pp. 179-186
    • Lawton, M.P.1    Brody, E.M.2
  • 60
    • 0035896462 scopus 로고    scopus 로고
    • Orally administered atropine enhances motor cortex excitability: a transcranial magnetic stimulation study in human subjects
    • Liepert J., Schardt S., Weiller C. Orally administered atropine enhances motor cortex excitability: a transcranial magnetic stimulation study in human subjects. Neurosci Lett 2001, 300:149-152.
    • (2001) Neurosci Lett , vol.300 , pp. 149-152
    • Liepert, J.1    Schardt, S.2    Weiller, C.3
  • 61
    • 0034920413 scopus 로고    scopus 로고
    • Motor cortex disinhibition in Alzheimer's disease
    • Liepert J., Bar K.J., Meske U., Weiller C. Motor cortex disinhibition in Alzheimer's disease. Clin Neurophysiol 2001, 112:1436-1441.
    • (2001) Clin Neurophysiol , vol.112 , pp. 1436-1441
    • Liepert, J.1    Bar, K.J.2    Meske, U.3    Weiller, C.4
  • 62
    • 0141523154 scopus 로고    scopus 로고
    • Novel modulatory mechanisms revealed by the sustained application of nicotine in the guinea-pig hippocampus in vitro
    • Mann E.O., Greenfield S.A. Novel modulatory mechanisms revealed by the sustained application of nicotine in the guinea-pig hippocampus in vitro. J Physiol 2003, 551:539-550.
    • (2003) J Physiol , vol.551 , pp. 539-550
    • Mann, E.O.1    Greenfield, S.A.2
  • 63
    • 0025061768 scopus 로고
    • Long-lasting facilitation of excitatory postsynaptic potentials in the rat hippocampus by acetylcholine
    • Markram H., Segal M. Long-lasting facilitation of excitatory postsynaptic potentials in the rat hippocampus by acetylcholine. J Physiol 1990, 427:381-393.
    • (1990) J Physiol , vol.427 , pp. 381-393
    • Markram, H.1    Segal, M.2
  • 64
    • 0025338394 scopus 로고
    • Acetylcholine potentiates responses to N-methyl-d-aspartate in the rat hippocampus
    • Markram H., Segal M. Acetylcholine potentiates responses to N-methyl-d-aspartate in the rat hippocampus. Neurosci Lett 1990, 113:62-65.
    • (1990) Neurosci Lett , vol.113 , pp. 62-65
    • Markram, H.1    Segal, M.2
  • 65
    • 0026528552 scopus 로고
    • The inositol 1,4,5-trisphosphate pathway mediates cholinergic potentiation of rat hippocampal neuronal responses to NMDA
    • Markram H., Segal M. The inositol 1,4,5-trisphosphate pathway mediates cholinergic potentiation of rat hippocampal neuronal responses to NMDA. J Physiol 1992, 447:513-533.
    • (1992) J Physiol , vol.447 , pp. 513-533
    • Markram, H.1    Segal, M.2
  • 66
    • 0028843619 scopus 로고
    • Microdialysis measurement of cortical and hippocampal acetylcholine release during sleep-wake cycle in freely moving cats
    • Marrosu F., Portas C., Mascia M.S., Casu M.A., Fà M., Giagheddu M., et al. Microdialysis measurement of cortical and hippocampal acetylcholine release during sleep-wake cycle in freely moving cats. Brain Res 1995, 671:329-332.
    • (1995) Brain Res , vol.671 , pp. 329-332
    • Marrosu, F.1    Portas, C.2    Mascia, M.S.3    Casu, M.A.4    Fà, M.5    Giagheddu, M.6
  • 67
    • 0032589299 scopus 로고    scopus 로고
    • Alpha4 but not alpha3 and alpha7 nicotinic acetylcholine receptor subunits are lost from the temporal cortex in Alzheimer's disease
    • Martin-Ruiz C.M., Court J.A., Molnar E., Lee M., Gotti C., Mamalaki A., et al. Alpha4 but not alpha3 and alpha7 nicotinic acetylcholine receptor subunits are lost from the temporal cortex in Alzheimer's disease. J Neurochem 1999, 73:1635-1640.
    • (1999) J Neurochem , vol.73 , pp. 1635-1640
    • Martin-Ruiz, C.M.1    Court, J.A.2    Molnar, E.3    Lee, M.4    Gotti, C.5    Mamalaki, A.6
  • 68
    • 0021962590 scopus 로고
    • Loss of M2 muscarine receptors in the cerebral cortex in Alzheimer's disease and experimental cholinergic denervation
    • Mash D.C., Flynn D.D., Potter L.T. Loss of M2 muscarine receptors in the cerebral cortex in Alzheimer's disease and experimental cholinergic denervation. Science 1985, 228:1115-1117.
    • (1985) Science , vol.228 , pp. 1115-1117
    • Mash, D.C.1    Flynn, D.D.2    Potter, L.T.3
  • 69
    • 33646126924 scopus 로고    scopus 로고
    • A decade of modeling Alzheimer's disease in transgenic mice
    • McGowan E., Eriksen J., Hutton M. A decade of modeling Alzheimer's disease in transgenic mice. Trends Genet 2006, 22:281-289.
    • (2006) Trends Genet , vol.22 , pp. 281-289
    • McGowan, E.1    Eriksen, J.2    Hutton, M.3
  • 70
    • 0021271971 scopus 로고
    • Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease
    • McKhann G., Drachman D., Folstein M., Katzman R., Price D., Stadlan E.M. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 1984, 34:939-944.
    • (1984) Neurology , vol.34 , pp. 939-944
    • McKhann, G.1    Drachman, D.2    Folstein, M.3    Katzman, R.4    Price, D.5    Stadlan, E.M.6
  • 71
    • 0344441293 scopus 로고    scopus 로고
    • The cholinergic innervation of the human cerebral cortex
    • Mesulam M.M. The cholinergic innervation of the human cerebral cortex. Prog Brain Res 2004, 145:67-78.
    • (2004) Prog Brain Res , vol.145 , pp. 67-78
    • Mesulam, M.M.1
  • 72
    • 77951741984 scopus 로고    scopus 로고
    • Learning discloses abnormal structural and functional plasticity at hippocampal synapses in the APP23 mouse model of Alzheimer's disease
    • Middei S., Roberto A., Berretta N., Panico M.B., Lista S., Bernardi G., et al. Learning discloses abnormal structural and functional plasticity at hippocampal synapses in the APP23 mouse model of Alzheimer's disease. Learn Mem 2010, 17:236-240.
    • (2010) Learn Mem , vol.17 , pp. 236-240
    • Middei, S.1    Roberto, A.2    Berretta, N.3    Panico, M.B.4    Lista, S.5    Bernardi, G.6
  • 73
    • 0037395881 scopus 로고    scopus 로고
    • The efficacy of galantamine in the treatment of Alzheimer's disease: comparison of patients previously treated with acetylcholinesterase inhibitors to patients with no prior exposure
    • Mintzer J.E., Kershaw P. The efficacy of galantamine in the treatment of Alzheimer's disease: comparison of patients previously treated with acetylcholinesterase inhibitors to patients with no prior exposure. Int J Geriatr Psychiatry 2003, 18:292-297.
    • (2003) Int J Geriatr Psychiatry , vol.18 , pp. 292-297
    • Mintzer, J.E.1    Kershaw, P.2
  • 74
    • 34147187704 scopus 로고    scopus 로고
    • Timing-dependent modulation of associative plasticity by general network excitability in the human motor cortex
    • Nitsche M.A., Roth A., Kuo M.F., Fischer A.K., Liebetanz D., Lang N., et al. Timing-dependent modulation of associative plasticity by general network excitability in the human motor cortex. J Neurosci 2007, 27:3807-3812.
    • (2007) J Neurosci , vol.27 , pp. 3807-3812
    • Nitsche, M.A.1    Roth, A.2    Kuo, M.F.3    Fischer, A.K.4    Liebetanz, D.5    Lang, N.6
  • 75
    • 0042697305 scopus 로고    scopus 로고
    • Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction
    • Oddo S., Caccamo A., Shepherd J.D., Murphy M.P., Golde T.E., Kayed R., et al. Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction. Neuron 2003, 39:409-421.
    • (2003) Neuron , vol.39 , pp. 409-421
    • Oddo, S.1    Caccamo, A.2    Shepherd, J.D.3    Murphy, M.P.4    Golde, T.E.5    Kayed, R.6
  • 77
    • 0018078940 scopus 로고
    • Correlation of cholinergic abnormalities with senile plaques and mental test scores in senile dementia
    • Perry E.K., Tomlinson B.E., Blessed G., Bergmann K., Gibson P.H., Perry R.H. Correlation of cholinergic abnormalities with senile plaques and mental test scores in senile dementia. Br Med J 1978, 2:1457-1459.
    • (1978) Br Med J , vol.2 , pp. 1457-1459
    • Perry, E.K.1    Tomlinson, B.E.2    Blessed, G.3    Bergmann, K.4    Gibson, P.H.5    Perry, R.H.6
  • 78
    • 0344420111 scopus 로고    scopus 로고
    • Increased TNFalpha production and Cox-2 activity in organotypic brain slice cultures from APPsw transgenic mice
    • Quadros A., Patel N., Crescentini R., Crawford F., Paris D., Mullan M. Increased TNFalpha production and Cox-2 activity in organotypic brain slice cultures from APPsw transgenic mice. Neurosci Lett 2003, 353:66-68.
    • (2003) Neurosci Lett , vol.353 , pp. 66-68
    • Quadros, A.1    Patel, N.2    Crescentini, R.3    Crawford, F.4    Paris, D.5    Mullan, M.6
  • 79
    • 0032530368 scopus 로고    scopus 로고
    • Nicotinic stimulation produces multiple forms of increased glutamatergic synaptic transmission
    • Radcliffe K.A., Dani J.A. Nicotinic stimulation produces multiple forms of increased glutamatergic synaptic transmission. J Neurosci 1998, 18:7075-7083.
    • (1998) J Neurosci , vol.18 , pp. 7075-7083
    • Radcliffe, K.A.1    Dani, J.A.2
  • 80
    • 0034720816 scopus 로고    scopus 로고
    • Galantamine in AD: A 6-month randomized, placebo-controlled trial with a 6-month extension. The Galantamine USA-1 Study Group
    • Raskind M.A., Peskind E.R., Wessel T., Yuan W. Galantamine in AD: A 6-month randomized, placebo-controlled trial with a 6-month extension. The Galantamine USA-1 Study Group. Neurology 2000, 54:2261-2268.
    • (2000) Neurology , vol.54 , pp. 2261-2268
    • Raskind, M.A.1    Peskind, E.R.2    Wessel, T.3    Yuan, W.4
  • 81
    • 0030849480 scopus 로고    scopus 로고
    • Stimulus/response curves as a method of measuring motor cortical excitability in man
    • Ridding M.C., Rothwell J.C. Stimulus/response curves as a method of measuring motor cortical excitability in man. Electroencephalogr Clin Neurophysiol 1997, 105:340-344.
    • (1997) Electroencephalogr Clin Neurophysiol , vol.105 , pp. 340-344
    • Ridding, M.C.1    Rothwell, J.C.2
  • 83
    • 0027947523 scopus 로고
    • Transcranial electrical stimulation of the motor cortex in man: further evidence for the site of activation
    • Rothwell J., Burke D., Hicks R., Stephen J., Woodforth I., Crawford M. Transcranial electrical stimulation of the motor cortex in man: further evidence for the site of activation. J Physiol 1994, 481:243-250.
    • (1994) J Physiol , vol.481 , pp. 243-250
    • Rothwell, J.1    Burke, D.2    Hicks, R.3    Stephen, J.4    Woodforth, I.5    Crawford, M.6
  • 84
    • 0035081475 scopus 로고    scopus 로고
    • Alzheimer's disease results from the cerebral accumulation and cytotoxicity of amyloid beta-protein
    • Selkoe D.J. Alzheimer's disease results from the cerebral accumulation and cytotoxicity of amyloid beta-protein. J Alzheimers Dis 2001, 3:75-80.
    • (2001) J Alzheimers Dis , vol.3 , pp. 75-80
    • Selkoe, D.J.1
  • 85
    • 0036403702 scopus 로고    scopus 로고
    • Deciphering the genetic basis of Alzheimer's disease
    • Selkoe D.J., Podlisny M.B. Deciphering the genetic basis of Alzheimer's disease. Annu Rev Genomics Hum Genet 2002, 3:67-99.
    • (2002) Annu Rev Genomics Hum Genet , vol.3 , pp. 67-99
    • Selkoe, D.J.1    Podlisny, M.B.2
  • 86
    • 33645989995 scopus 로고    scopus 로고
    • Non-fibrillar beta-amyloid abates spike-timing-dependent synaptic potentiation at excitatory synapses in layer 2/3 of the neocortex by targeting postsynaptic AMPA receptors
    • Shemer I., Holmgren C., Min R., Fülöp L., Zilberter M., Sousa K.M., et al. Non-fibrillar beta-amyloid abates spike-timing-dependent synaptic potentiation at excitatory synapses in layer 2/3 of the neocortex by targeting postsynaptic AMPA receptors. Eur J Neurosci 2006, 23:2035-2047.
    • (2006) Eur J Neurosci , vol.23 , pp. 2035-2047
    • Shemer, I.1    Holmgren, C.2    Min, R.3    Fülöp, L.4    Zilberter, M.5    Sousa, K.M.6
  • 87
    • 40649095625 scopus 로고    scopus 로고
    • Network dysfunction in Alzheimer's disease: does synaptic scaling drive disease progression?
    • Small D.H. Network dysfunction in Alzheimer's disease: does synaptic scaling drive disease progression?. Trends Mol Med 2008, 14:103-108.
    • (2008) Trends Mol Med , vol.14 , pp. 103-108
    • Small, D.H.1
  • 89
    • 4744354513 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptor immunohistochemistry in Alzheimer's disease and dementia with Lewy bodies: differential neuronal and astroglial pathology
    • Teaktong T., Graham A.J., Court J.A., Perry R.H., Jaros E., Johnson M., et al. Nicotinic acetylcholine receptor immunohistochemistry in Alzheimer's disease and dementia with Lewy bodies: differential neuronal and astroglial pathology. J Neurol Sci 2004, 225:39-49.
    • (2004) J Neurol Sci , vol.225 , pp. 39-49
    • Teaktong, T.1    Graham, A.J.2    Court, J.A.3    Perry, R.H.4    Jaros, E.5    Johnson, M.6
  • 90
    • 0037440372 scopus 로고    scopus 로고
    • Alzheimer's disease is associated with a selective increase in alpha7 nicotinic acetylcholine receptor immunoreactivity in astrocytes
    • Teaktong T., Graham A., Court J., Perry R., Jaros E., Johnson M., et al. Alzheimer's disease is associated with a selective increase in alpha7 nicotinic acetylcholine receptor immunoreactivity in astrocytes. Glia 2003, 41:207-211.
    • (2003) Glia , vol.41 , pp. 207-211
    • Teaktong, T.1    Graham, A.2    Court, J.3    Perry, R.4    Jaros, E.5    Johnson, M.6
  • 91
    • 0030777850 scopus 로고    scopus 로고
    • Alterations in glutamate receptor 2/3 subunits and amyloid precursor protein expression during the course of Alzheimer's disease and Lewy body variant
    • Thorns V., Mallory M., Hansen L., Masliah E. Alterations in glutamate receptor 2/3 subunits and amyloid precursor protein expression during the course of Alzheimer's disease and Lewy body variant. Acta Neuropathol 1997, 94:539-548.
    • (1997) Acta Neuropathol , vol.94 , pp. 539-548
    • Thorns, V.1    Mallory, M.2    Hansen, L.3    Masliah, E.4
  • 92
    • 3342908640 scopus 로고    scopus 로고
    • Beta-amyloid peptide at sublethal concentrations downregulates brain-derived neurotrophic factor functions in cultured cortical neurons
    • Tong L., Balazs R., Thornton P.L., Cotman C.W. Beta-amyloid peptide at sublethal concentrations downregulates brain-derived neurotrophic factor functions in cultured cortical neurons. J Neurosci 2004, 24:6799-6809.
    • (2004) J Neurosci , vol.24 , pp. 6799-6809
    • Tong, L.1    Balazs, R.2    Thornton, P.L.3    Cotman, C.W.4
  • 93
    • 2542584749 scopus 로고    scopus 로고
    • Progressive age-related development of Alzheimer-like pathology in APP/PS1 mice
    • Trinchese F., Liu S., Battaglia F., Walter S., Mathews P.M., Arancio O. Progressive age-related development of Alzheimer-like pathology in APP/PS1 mice. Ann Neurol 2004, 55:801-814.
    • (2004) Ann Neurol , vol.55 , pp. 801-814
    • Trinchese, F.1    Liu, S.2    Battaglia, F.3    Walter, S.4    Mathews, P.M.5    Arancio, O.6
  • 94
    • 0033135312 scopus 로고    scopus 로고
    • Homeostatic plasticity in neuronal networks: the more things change, the more they stay the same
    • Turrigiano G.G. Homeostatic plasticity in neuronal networks: the more things change, the more they stay the same. Trends Neurosci 1999, 22:221-227.
    • (1999) Trends Neurosci , vol.22 , pp. 221-227
    • Turrigiano, G.G.1
  • 95
    • 0742323527 scopus 로고    scopus 로고
    • Homeostatic plasticity in the developing nervous system
    • Turrigiano G.G., Nelson S.B. Homeostatic plasticity in the developing nervous system. Nat Rev Neurosci 2004, 5:97-107.
    • (2004) Nat Rev Neurosci , vol.5 , pp. 97-107
    • Turrigiano, G.G.1    Nelson, S.B.2
  • 96
    • 33747153860 scopus 로고    scopus 로고
    • Deposition of mouse amyloid beta in human APP/PS1 double and single AD model transgenic mice
    • van Groen T., Kiliaan A.J., Kadish I. Deposition of mouse amyloid beta in human APP/PS1 double and single AD model transgenic mice. Neurobiol Dis 2006, 23:653-662.
    • (2006) Neurobiol Dis , vol.23 , pp. 653-662
    • van Groen, T.1    Kiliaan, A.J.2    Kadish, I.3
  • 98
    • 2542427690 scopus 로고    scopus 로고
    • Oligomers on the brain: the emerging role of soluble protein aggregates in neurodegeneration
    • Walsh D.M., Selkoe D.J. Oligomers on the brain: the emerging role of soluble protein aggregates in neurodegeneration. Protein Pept Lett 2004, 11:213-228.
    • (2004) Protein Pept Lett , vol.11 , pp. 213-228
    • Walsh, D.M.1    Selkoe, D.J.2
  • 99
    • 0029919523 scopus 로고    scopus 로고
    • LTD and LTP induced by transcranial magnetic stimulation in auditory cortex
    • Wang H., Wang X., Scheich H. LTD and LTP induced by transcranial magnetic stimulation in auditory cortex. Neuroreport 1996, 7:521-525.
    • (1996) Neuroreport , vol.7 , pp. 521-525
    • Wang, H.1    Wang, X.2    Scheich, H.3
  • 100
    • 0033695958 scopus 로고    scopus 로고
    • Activity coregulates quantal AMPA and NMDA currents at neocortical synapses
    • Watt A.J., van Rossum M.C., MacLeod K.M., Nelson S.B., Turrigiano G.G. Activity coregulates quantal AMPA and NMDA currents at neocortical synapses. Neuron 2000, 26:659-670.
    • (2000) Neuron , vol.26 , pp. 659-670
    • Watt, A.J.1    van Rossum, M.C.2    MacLeod, K.M.3    Nelson, S.B.4    Turrigiano, G.G.5
  • 102
    • 0033152605 scopus 로고    scopus 로고
    • Differential effects on motorcortical inhibition induced by blockade of GABA uptake in humans
    • Werhahn K.J., Kunesch E., Noachtar S., Benecke R., Classen J. Differential effects on motorcortical inhibition induced by blockade of GABA uptake in humans. J Physiol 1999, 517:591-597.
    • (1999) J Physiol , vol.517 , pp. 591-597
    • Werhahn, K.J.1    Kunesch, E.2    Noachtar, S.3    Benecke, R.4    Classen, J.5
  • 104
    • 0035859879 scopus 로고    scopus 로고
    • A 1-year, randomized, placebo-controlled study of donepezil in patients with mild to moderate AD
    • Winblad B., Engedal K., Soininen H., Verhey F., Waldemar G., Wimo A., et al. A 1-year, randomized, placebo-controlled study of donepezil in patients with mild to moderate AD. Neurology 2001, 57:489-495.
    • (2001) Neurology , vol.57 , pp. 489-495
    • Winblad, B.1    Engedal, K.2    Soininen, H.3    Verhey, F.4    Waldemar, G.5    Wimo, A.6
  • 105
    • 34249683625 scopus 로고    scopus 로고
    • A six-month double-blind, randomized, placebo-controlled study of a transdermal patch in Alzheimer's disease - rivastigmine patch versus capsule
    • Winblad B., Cummings J., Andreasen N., Grossberg G., Onofrj M., Sadowsky C., et al. A six-month double-blind, randomized, placebo-controlled study of a transdermal patch in Alzheimer's disease - rivastigmine patch versus capsule. Int J Geriatr Psychiatry 2007, 22:456-467.
    • (2007) Int J Geriatr Psychiatry , vol.22 , pp. 456-467
    • Winblad, B.1    Cummings, J.2    Andreasen, N.3    Grossberg, G.4    Onofrj, M.5    Sadowsky, C.6
  • 106
    • 58149203447 scopus 로고    scopus 로고
    • Use of rivastigmine transdermal patch in the treatment of Alzheimer's disease
    • Winblad B., Machado J.C. Use of rivastigmine transdermal patch in the treatment of Alzheimer's disease. Expert Opin Drug Deliv 2008, 5:1377-1386.
    • (2008) Expert Opin Drug Deliv , vol.5 , pp. 1377-1386
    • Winblad, B.1    Machado, J.C.2
  • 107
    • 0032754141 scopus 로고    scopus 로고
    • Suppressive action produced by beta-amyloid peptide fragment 31-35 on long-term potentiation in rat hippocampus is N-methyl-d-aspartate receptor-independent: it is offset by (-)huperzine A
    • Ye L., Qiao J.T. Suppressive action produced by beta-amyloid peptide fragment 31-35 on long-term potentiation in rat hippocampus is N-methyl-d-aspartate receptor-independent: it is offset by (-)huperzine A. Neurosci Lett 1999, 275:187-190.
    • (1999) Neurosci Lett , vol.275 , pp. 187-190
    • Ye, L.1    Qiao, J.T.2
  • 108
    • 13444280311 scopus 로고    scopus 로고
    • High selective expression of alpha7 nicotinic receptors on astrocytes in the brains of patients with sporadic Alzheimer's disease and patients carrying Swedish APP 670/671 mutation: a possible association with neuritic plaques
    • Yu W.F., Guan Z.Z., Bogdanovic N., Nordberg A. High selective expression of alpha7 nicotinic receptors on astrocytes in the brains of patients with sporadic Alzheimer's disease and patients carrying Swedish APP 670/671 mutation: a possible association with neuritic plaques. Exp Neurol 2005, 192:215-225.
    • (2005) Exp Neurol , vol.192 , pp. 215-225
    • Yu, W.F.1    Guan, Z.Z.2    Bogdanovic, N.3    Nordberg, A.4
  • 109
    • 0029787246 scopus 로고    scopus 로고
    • Effects of antiepileptic drugs on motor cortex excitability in humans: a transcranial magnetic stimulation study
    • Ziemann U., Lönnecker S., Steinhoff B.J., Paulus W. Effects of antiepileptic drugs on motor cortex excitability in humans: a transcranial magnetic stimulation study. Ann Neurol 1996, 40:367-378.
    • (1996) Ann Neurol , vol.40 , pp. 367-378
    • Ziemann, U.1    Lönnecker, S.2    Steinhoff, B.J.3    Paulus, W.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.