The cholinergic innervation of the human cerebral cortex

Progress in Brain Research

Volumn 145, Issue , 2004, Pages 67-78

  Mesulam, M Marsel ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLINE ACETYLTRANSFERASE; DOPAMINE; NORADRENALIN; SEROTONIN;

AGING; ALZHEIMER DISEASE; AMYGDALOID NUCLEUS; BRAIN CORTEX; CELL CULTURE; CHOLINERGIC NERVE CELL; CHOLINERGIC SYSTEM; CONFERENCE PAPER; CYTOCHEMISTRY; DEMENTIA; DOPAMINERGIC SYSTEM; ELECTRON MICROSCOPY; GLOBUS PALLIDUS; HEMISPHERE; HIPPOCAMPUS; HUMAN; LOCUS CERULEUS; MEMORY; NERVE CELL PLASTICITY; NERVE DEGENERATION; OLFACTORY BULB; OLIVARY NUCLEUS; PARASYMPATHETIC INNERVATION; PHYSIOLOGY; PRIMATE; PRIORITY JOURNAL; SUBSTANTIA INNOMINATA; TOPOGRAPHY; VENTRAL TEGMENTUM;

EID: 0344441293     PISSN: 00796123     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0079-6123(03)45004-8     Document Type: Conference Paper

References (102)

1. Arendt, T., Bigl, V., Tennstedt, A. and Arendt, A. (1985) Neuronal loss in different parts of the nucleus basalis is related to neuritic plaque formation in cortical target areas in Alzheimer's disease. Neuroscience, 14: 1-14.
2. Aston-Jones, G., Shaver, R. and Dinan, T.G. (1985) Nucleus basalis neurons exhibit axonal branching with decreased impulse conduction velocity in rat cerebrocortex. Brain Res., 325: 271-285.
3. Auerbach, J.M. and Segal, M. (1994) A novel cholinergic induction of long-term potentiation in rat hippocampus. J. Neurophysiol., 72: 2034-2040.
4. Baskerville, K.A., Schweitzer, J.B. and Herron, P. (1997) Effects of cholinergic depletion on experience-dependent plasticity in the cortex of the rat. Neuroscience, 80: 1159-1169.
5. Bear, M.F. and Singer, W. (1986) Modulation of visual cortical plasticity by acetylcholine and noradrenaline. Nature, 320: 172-176.
6. Berger-Sweeney, J., Heckers, S., Mesulam, M.-M., Wiley, R.G., Lappi, D.A. and Sharma, M. (1994) Differential effects upon spatial navigation of immunotoxin-induced cholinergic lesions of the medial septal area and nucleus basalis magnocellularis. J. Neurosci., 14: 4507-4519.
7. Bonner, T.I., Buckley, N.J., Young, A.C. and Brann, M.R. (1987) Identification of a family of muscarinic acetylcholine receptor genes. Science, 237: 527-532.
8. Bonner, T.I., Young, A.C., Brann, M.R. and Buckley, N.J. (1988) Cloning and expression of the human and rat m5 muscarinic acetylcholine receptor genes. Neuron, 1: 403-410.
9. Buckley, N.J., Bonner, T.I. and Brann, M.R. (1988) Localization of muscarinic receptor mRNAs in rat brain. J. Neurosci., 8: 4646-4652.
10. Buszáki, G. (1989) Commentary: Two-stage model of memory trace formation: A role for 'noisy' brain states. Neuroscience, 31: 551-570.
11. Cruikshank, S.J. and Weinberger, N.M. (1996) Evidence for the Hebbian hypothesis in experience-dependent physiological plasticity of neocortex: a critical review. Brain Res. Rev., 22: 191-228.
12. DeLima, A.D. and Singer, W. (1986) Cholinergic innervation of the cat striate cortex: A choline acetyltransferase immunocytochemical analysis. J. Comp. Neurol., 250: 324-338.
13. DeLong, M.R. (1971) Activity of pallidal neurons during movement. J. Neurophysiol., 34: 414-427.
14. Dias, E.C., Compaan, D.M., Mesulam, M.-M. and Segraves, M.A. (1996) Selective disruption of memory-guided saccades with injecton of a cholinergic antagonist in the frontal eye field of monkey. Soc. Neurosci. Abstr., 22: 418.
15. Drachman, D.A. and Leavitt, J. (1974) Human memory and the cholinergic system-A relationship to aging? Arch. Neurol., 30: 113-121.
16. Dringenberg, H.C. and Vanderwolf, C.H. (1996) Cholinergic activation of the electrocorticogram: an amygdaloid activating system. Exp. Brain Res., 108: 285-296.
17. Eggermann, E., Serafin, M., Bayer, L., Machard, D., Saint-Mleux, B., Jones, B.E. and Mühlethaler, M. (2001) Orexins/hyporectins excite basal forebrain cholinergic neurons. Neuroscience, 108: 177-181.
18. Emre, M., Heckers, S., Mash, D.C., Geula, C. and Mesulam, M.-M. (1993) Cholinergic innervation of the amygdaloid complex in the human brain and its alterations in old age and Alzheimer's disease. J. Comp. Neurol., 336: 117-134.
19. Everitt, B.J., Sirkiä, T.E., Roberts, A.C., Jones, G.H. and Robbins, T.W. (1988) Distribution and some projections of cholinergic neurons in the brain of the common marmoset, Callithrix jaccus. J. Comp. Neurol., 271: 533-558.
20. Farkas, R.H., Nakajima, S. and Nakajima, Y. (1994) Neurotensin excites basal forebrain cholinergic neurons: ionic and signal-transduction mechanisms. Proc. Natl. Acad. Sci. (USA), 91: 2853-2857.
21. Freund, T.F. and Meskenaite, V. (1992) γ-Amynobutyric acid-containing basal forebrain neurons innervate inhibitory interneurons in the neocortex. Proc. Natl. Acad. Sci. (USA), 89: 738-742.
22. Frotscher, M. and Leranth, C. (1985) Cholinergic innervation of the rat hippocampus as revealed by choline acetyltransferase immunocytochemistry: A combined light and electron microscopic study. J. Comp. Neurol., 239: 237-246.
23. Gaspar, P., Berger, B., Alvarez, C., Vigny, A. and Henry, J.P. (1985) Catecholaminergic innervation of the septal area in man: immunocytochemical study using TH and DBH antibodies. J. Comp. Neurol., 241: 12-33.
24. Geula, C. and Mesulam, M.-M. (1989) Cortical cholinergic fibers in aging and Alzheimer's disease: a morphometric study. Neuroscience, 33: 469-481.
25. Geula, C. and Mesulam, M.-M. (1994) Cholinergic systems and related neuropathological predilection patterns in Alzheimer disease. In: R.D. Terry, R. Katzman and K.L. Bick (Eds.), Alzheimer Disease. Raven Press, New York, pp. 263-294.
26. Geula, C., Mesulam, M.-M., Tokuno, H. and Kuo, C.C. (1993a) Developmentally transient expression of acetylcholinesterase within cortical pyramidal neurons of the rat brain. Dev. Brain Res., 76: 23-31.
27. Geula, C., Schatz, C.R. and Mesulam, M.-M. (1993b) Differential localization of NADPH-diaphorase and calbindin-D28k within the cholinergic neurons of the basal forebrain, striatum and brainstem in the rat, monkey, baboon and human. Neuroscience, 54: 461-476.
28. Gilmor, M.L., Erickson, J.D., Varoqui, H., Hersh, L.B., Bennett, D.A., Cochran, E.J., Mufson, E.J. and Levey, A.I. (1999) Preservation of nucleus basalis neurons containing choline acetyltransferase and the vesicular acetylcholine transporter in the elderly with mild cognitive impairment and earlty Alzheimer's disease. J. Comp. Neurol., 411: 693-704.
29. Gorry, J.D. (1963) Studies on the comparative anatomy of the ganglion basale of Meynert. Acta Anat., 55: 51-104.
30. Gouras, G.K., Rance, N.E., Young, W.S., III and Koliatsos, V.E. (1992) Tyrosine-hydroxylase containing neurons in the primate basal forebrain magnocellular complex. Brain Res., 584: 287-293.
31. Gritti, I., Mainville, L. and Jones, B.E. (1993) Codistribution of GABA with acetylcholine-synthesizing neurons in the basal forebrain of the rat. J. Comp. Neurol., 329: 438-457.
32. Hammond, E.J., Meador, K.J., Aunq-Din, R. and Wilder, B.J. (1987) Cholinergic modulation of human P3 event-related potentials. Neurology, 37: 346-350.
33. Harata, N., Tateishi, N. and Akaike, N. (1991) Acetylcholine receptors in dissociated nucleus basalis of Meynert neurons of the rat. Neurosci. Lett., 130: 153-156.
34. Hasselmo, M.E. (1992) cholinergic modulation of cortical associative memory function. J. Neurophysiol., 67: 1230-1246.
35. Heckers, S., Ohtake, T., Wiley, R.G., Lappi, D.A., Geula, C. and Mesulam, M.-M. (1994) Complete and selective cholinergic denervation of rat neocortex and hippocampus but not amygdala by an immunotoxin agoinst the p75 NGF receptor. J. Neurosci., 14: 1271-1289.
36. Henderson, Z. (1987) A small proportion of cholinergic neurones in the nucleus basalis magnocellularis of ferret appear to stain positively for tyrosine hydroxylase. Brain Res., 412: 363-369.
37. Henderson, Z. and Evans, S. (1991) Presence of a cholinergic projection from ventral striatum to amygdala that is not immunoreactive for NGF receptor. Neurosci. Lett., 127: 73-76.
38. Himmelheber, A.M., Sarter, M. and Bruno, J.P. (2001) The effects of manipulations of attentional demand on cortical acetylcholine release. Cog. Brain Res., 12: 353-370.
39. Huerta, P.T. and Lisman, J.E. (1993) Heightened synaptic plasticity of hippocampal CAl neurons during a cholinergically induced rhythmic state. Nature, 364: 723-725.
40. Ingham, C.A., Bolam, J.P., Wainer, B.H. and Smith, A.D. (1985) A correlated light and electron microscopic study of identified cholinergic basal forebrain neurons that project to the cortex in the rat. J. Comp. Neurol., 239: 176-192.
41. Jones, B.E. and Cuello, A.C. (1989) Afferents to the basal forebrain cholinergic cell area from pontomesencephaliccatecholamine, serotonin and acetylcholine-neurons. Neuroscience, 31: 37-61.
42. Kilgard, M.P. and Merzenich, M.M. (1998) Cortical map reorganization enabled by nucleus basalis activity. Science, 279: 1714-1718.
43. Kordower, J.H., Chen, E.-Y., Sladek, J.R., Jr. and Mufson, E.J. (1994) TRK-immunoreactivity in the monkey central nervous system: Forebrain. J. Comp. Neurol., 349: 20-35.
44. Kostovic, I., Skavic, J. and Strinovic, D. (1988) Acetylcholinesterase in the human frontal associative cortex during the period of cognitive development: Early laminar shifts and late innervation of pyramidal neurons. Neurosci. Lett., 90: 107-112.
45. Kubo, T., Fukuda, K., Mikami, A., Maeda, A., Takahashi, H., Mishina, M., Haga, T., Haga, K., Ichiyama, A., Kangawa, K., Kojima, M., Matsuo, H., Hirose, T. and Numa, S. (1986) Cloning, sequencing and expression of complementary DNA encoding the muscarinic acetylcholine receptor. Nature, 323: 411-416.
46. Kutscher, C.L. (1991) Development of transient acetylcholinesterase staining in cells and permanent staining in fibers in cortex of rat brain. Brain Res. Bull., 27: 641-649.
47. Levey, A.I., Kitt, C.A., Simonds, W.F., Price, D.L. and Brann, M.R. (1991) Identification and localization of muscarinic acetylcholine receptor protein in brain with subtype-specific antibodies. J. Neurosci., 11: 3218-3226.
48. Levey, A.I., Edmunds, S.M., Heilman, C.J., Desmond, T.J. and Frey, K.A. (1994) Localization of muscarinic m3 receptor protein and M3 receptor binding in the rat brain. Neuroscience, 63: 207-221.
49. Lidow, M.S., Gallager, D.W., Rakic, P. and Goldman-Rakic, P.S. (1989) Regional differences in the distribution of muscarinic cholinergic receptors in the macaque cerebral cortex. J. Comp. Neurol., 289: 247-259.
50. Loewi, O. (1921) Über humorale Übertragbarkeit der Herznervenwirkung. Pflügers Arch. Ges. Physiol., 189: 239-242.
51. Martinez-Murillo, R., Villalba, R.M. and Rodrigo, J. (1990) Immunocytochemical localization of cholinergic terminals in the region of the nucleus basalis magnocellularis of the rat: A correlated light and electron microscopic study. Neuroscience. 36: 361-376.
52. Mash, D.C., White, W.F. and Mesulam, M.-M. (1988) Distribution of muscarinic receptor subtypes within architectonic subregions of the primate cerebral cortex. J. Comp. Neurol., 278: 265-274.
53. McCormick, D.A. and Prince, D.A. (1985) Two types of muscarinic responses to acetylcholine in mammalian cortical neurons. Proc. Natl. Acad. Sci. USA, 82: 6344-6348.
54. McGaugh, J.L., Introini-Collison, I.B., Cahill, L.F., Castellano, C., Dalmaz, C., Parent, M.B. and Williams, C.L. (1993) Neuromodulatory systems and memory storage: role of the amygdala. Behav. Brain Res., 58: 81-90.
55. Mesulam, M.-M. (1995) Cholinergic pathways and the ascending reticular activating system of the human brain. Ann. N.Y. Acad. Sci., 757: 169-179.
56. Mesulam, M.-M. (1999) Neuroplasticity failure in Alzheimer's disease: Bridging the gap between plaques and tangles. Neuron, 24: 521-529.
57. Mesulam, M.-M. and Geula, C. (1988a)Acetylcholinesteraserich pyramidal neurons in the human neocortex and hippocampus: absence at birth, development during the life span, and dissolution in Alzheimer's disease. Ann. Neurol., 24: 765-773.
58. Mesulam, M.-M. and Geula, C. (1988b). Nucleus basalis (Ch4) and cortical cholinergic innervation in the human brain: observations based on the distribution of acetylcholinesterase and choline acetyltransferase: J. Comp. Neurol., 275: 216-240.
59. Mesulam, M.-M. and Geula, C. (1991) Acetylcholinesteraserich neurons of the human cerebral cortex: cytoarchitectonic and ontogenetic patterns of distribution. J. Comp. Neurol., 306:193-220.
60. Mesulam, M.-M. and Geula, C. (1993) Chemoarchitectonics of axonal and perikaryal acetylcholinesterase along information processing systems of the human cerebral cortex. Brain Res. Bull., 33: 137-153.
61. Mesulam, M.-M. and Mufson, E.J. (1984) Neural inputs into the nucleus basalis of the substantia innominata (Ch4) in the rhesus monkey. Brain, 107: 253-274.
62. Mesulam, M.-M., Mufson, E.J., Levey, A.I. and Wainer, B.H. (1983a) Cholinergic innervation of cortex by the basal forebrain: cytochemistry and cortical connections of the septal area, diagonal band nuclei, nucleus basalis (substantia innominata), and hypothalamus in the rhesus monkey. J. Comp. Neurol., 214: 170-197.
63. Mesulam, M.M., Mufson, E.J., Wainer, B.H. and Levey, A.I. (1983b) Central cholinergic pathways in the rat: an overview based on an alternative nomenclature (Ch1-Ch6). Neuroscience, 10: 1185-1201.
64. Mesulam, M.-M., Geula, C., Bothwell, M.A. and Hersh, L.B. (1989) Human reticular formation: cholinergic neurons of the pedunculopontine and laterodorsal tegmental nuclei and some cytochemical comparisons to forebrain cholinergic neurons. J. Comp. Neurol., 283: 611-633.
65. Mesulam, M.-M., Hersh, L.B., Mash, D.C. and Geula, C. (1992) Differential cholinergic innervation within functional subdivisions of the human cerebral cortex: a choline acetyltransferase study. J. Comp. Neurol., 318: 316-328.
66. Metherate, R., Cox, C.L. and Ashe, J.H. (1992) Cellular bases of neocortical activation: Modulation of neuronal oscillations by the nucleus basalis and endogenous acetylcholine. J. Neurosci., 12: 4701-4711.
67. Mrzljak, L., Levey, A.I. and Goldman-Rakic, P.S. (1993) Association of m1 and m2 muscarinic receptor proteins with asymmetric synapses in the primate cerebral cortex: Morphological evidence for cholinergic modulation of excitatory neurotransmission. Proc. Nat. Acad. Sci. (USA), 90: 5194-5198.
68. Mufson, E.J., Bothwell, M., Hersh, L.B. and Kordower, J.H. (1989) Nerve growth factor receptor immunoreactive profiles in the normal, aged human basal forebrain: Colocalization with cholinergic neurons. J. Comp. Neurol., 285: 196-217.
69. Nakajima, Y., Nakajima, S., Obata, K., Carlson, C.G. and Yamaguchi, K. (1985) Dissociated cell culture of cholinergic neurons from nucleus basalis of Meynert and other basal forebrain nuclei. Proc. Nat. Acad. Sci. (USA), 82: 6325-6329.
70. Palacios, G. (1990) The endomembrane system of cholinergic and non-cholinergic neurons in the medial septal nucleus and vertical limb of the diagonal band of Broca: A cytochemical and immunocytochemical study. J. Histochem. Cytochem., 38: 563-571.
71. Peralta, E.G., Ashkenazi, A., Winslow, J.W., Smith, D.H., Ramachandran, J. and Capon, D.J. (1987) Distinct primary structures, ligand-binding properties and tissue-specific expression of four human muscarinic acetylcholine receptors. EMBO J., 6: 3923-3929.
72. Power, A.E., Thal, L.J. and McGaugh, J.L. (2002) Lesions of the nucleus basalis magnocellularis induced by 192 IgG-saporin block memory enhancement with posttraining norepinephrine in the basolateral amygdala. Proc. Natl. Acad. Sci. (USA), 99: 2315-2319.
73. Ramon-Moliner, E. and Nauta, W.J.H. (1966) The isodendritic core of the brain. J. Comp. Neurol., 126: 311-336.
74. Ridley, R.M., Murray, T.K., Johnson, J.A. and Baker, H.F. (1986) Learning impairment following lesion of the basal nucleus of Meynert in the marmoset: Modification by cholinergic drugs. Brain Res., 376: 108-116.
75. Sato, H., Hata, V., Hagihara, K. and Tsumoto, T. (1987) Effects of cholinergic depletion on neuron activities in the cat visual cortex. J. Neurophysiol., 58: 781-794.
76. Satoh, K. and Fibiger, H.C. (1985) Distribution of central cholinergic neurons in the baboon (Papio papio). I. General morphology. J. Comp. Neurol., 236: 197-214.
77. Schröder, H., Zilles, K., Maelicke, A. and Hajós, F. (1989) Immunohisto- and cytochemical localization of cortical cholinoceptors in rat and man. Brain Res., 502: 287-295.
78. Schröder, H., Zilles, K., Luiten, P.G.M. and Strosberg, A.D. (1990) Immunocytochemical visualization of muscarinic cholinoceptors in the human cerebral cortex. Brain Res., 514:249-258.
79. Selden, N.R., Gitelman, D.R., Salamon-Murayama, N., Parrish, T.B. and Mesulam, M.-M. (1998) Trajectories of cholinergic pathways within the cerebral hemispheres of the human brain. Brain, 121: 2249-2257.
80. Silver, A. (1974) The Biology of Cholinesterases. American Elsevier Publishing, New York.
81. Smiley, J.F. and Mesulam, M.-M. (1999) Cholinergic neurons of the nucleus basalis of Meynert (Ch4) receive cholinergic, catecholaminergic, and GABAergic synapses: an electron microscopic investigation in the monkey. Neuroscience, 88: 241-255.
82. Smiley, J.F., Morrell, F. and Mesulam, M.-M. (1997) Cholinergic synapses in human cerebral cortex: an ultra-structural study in serial sections. Exper. Neurol., 144: 361-368.
83. Smiley, J.F., Levey, A.I. and Mesulam, M.-M. (1998) Infracortical interstitial cells concurrently expressing m2-muscarinic receptors, AChE, and NADPH-d in the human and monkey cerebral cortex. Neuroscience, 84: 755-769.
84. Smiley, J.F., Levey, A.I. and Mesulam, M.-M. (1999a) m2 muscarinic receptor immunolocalization in cholinergic cells of the monkey basal forebrain and striatum. Neuroscience, 90: 803-814.
85. Smiley, J.F., Subramanian, M. and Mesulam, M.-M. (1999b) Monoaminergic-cholinergic interactions in the primate basal forebrain. Neuroscience, 93: 817-829.
86. Steriade, M., Amzica, F. and Nunez, A. (1993) Cholinergic and noradrenergic modulation of the slow (approximately 0.3 Hz) oscillation in neocortical cells. J. Neurophysiol., 70: 1385-1400.
87. Tanaka, Y., Sakurai, M. and Hayashi, S. (1989) Effect of scopolamine and HP029, a cholinesterase inhibitor, on long-term potentiation in hippocampal slices of guinea pig. Neurosci. Lett., 98: 179-183.
88. Umbriaco, D., Watkins, K.C., Descarries, L., Cozzari, C. and Hartman, B.K. (1994) Ultrastructural and morphometric features of the acetylcholine innervation in adult rat parietal cortex: an electron microscopic study in serial sections. J. Comp. Neurol., 348: 351-373.
89. Vilaró, M.T., Wiederhold, K.-H., Palacios, J.M. and Mengod, G. (1992) Muscarinic M2 receptor mRNA expression and receptor binding in cholinergic and non-cholinergic cells in the rat brain: a correlative study using in situ hybridization histochemistry and receptor autoradiography Neuroscience, 47: 367-393.
90. Voytko, M.L., Olton, D.S., Richardson, R.T., Gorman, L.K., Tobin, J.R. and Price, D.L. (1994) Basal forebrain lesions in monkeys disrupt attention but not learning and memory. J. Neurosci., 14: 167-186.
91. Wainer, B.H., Bolam, J.P., Freund, T.F. and Henderson, Z. (1984) Cholinergic synapses in the rat brain: A correlated light and electron microscopic immunohistochemical study employing a monoclonal antibody against choline acetyl-transferase. Brain Res., 308: 69-76.
92. Walker, L.C., Tigges, M. and Tigges, J. (1983) Ultrastructure of neurons in the nucleus basalis of Meynert in squirrel monkey. J. Comp. Neurol., 217: 158-166.
93. Walker, L.C., Koliatsos, V.E., Kitt, C.A., Richardson, R.T., Rökaeus, A. and Price, D.L. (1989) Peptidergic neurons in the basal forebrain magnocellular complex of the rhesus monkey. J. Comp. Neurol., 280: 272-282.
94. Wenk, G.L., Stoehr, J.D., Quintana, G., Mobley, S. and Wiley, R.G. (1994) Behavioral, biochemical, histological, and electrophysiological effects of 192 IgG-saporin injections into the basal forebrain of rats. J. Neurosci., 14: 5986-5995.
95. Whalen, P.J., Knapp, B.S. and Pascoe, J.P. (1994) Neuronal activity within the nucleus basalis and conditioned neocortical electroencephalographic activation. J. Neurosci., 14: 1623-1633.
96. Wilson, F.A.W. and Rolls, E.T. (1990) Neuronal responses related to novelty and familiarity of visual stimuli in the substantia innominata, diagonal band of Broca and periventricular region of the primate basal forebrain. Exp. Brain Res., 80: 104-120.
97. Wisniowski, L., Ridley, R.M., Baker, H.F. and Fine, A. (1992) Tyrosine hydroylase-immunoreactive neurons in the nucleus basalis of the common marmoset (Callithrixjaccus). J. Comp. Neurol., 325: 379-387.
98. Wu, C.-K., Mesulam, M.-M. and Geula, C. (1997) Age-related loss of calbindin from basal forebrain cholinergic neurons. NeuroReport, 8: 2209-2213.
99. Záborszky, L., Gaykema, R.P., Swanson, D.J. and Cullinan, W.E. (1997) Cortical input to the basal forebrain. Neuroscience, 79: 1051-1078.
100. Zhu, X.O. and Waite, P.M.E. (1998) Cholinergic depletion reduces plasticity of barrel field cortex. Cereb. Cortex, 8: 63-72.
101. Zilles, K., Werner, L., Qü, M., Schleicher, A. and Gross, G. (1991) Quantitative autoradiography of 11 different transmitter binding sites in the basal forebrain region of the rat-evidence of heterogeneity in distribution patterns. Neuroscience, 42: 473-481.
102. Zilles, K., Schlaug, G., Matelli, M., Luppino, G., Schleicher, A., Qu, M., Dabringhaus, A., Seitz, R. and Roland, P. (1995) Mapping of human and macaque sensorimotor areas by integrating architectonic, transmitter receptor, MRI and PET data. J. Anat., 187: 515-537.