Degradation of the tricyclic antipsychotic drug chlorpromazine under environmental conditions, identification of its main aquatic biotic and abiotic transformation products by LC-MS n and their effects on environmental bacteria

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 889-890, Issue , 2012, Pages 24-38

  Trautwein, Christoph ^a,b,c   Kümmerer, Klaus ^c  

^a UNIVERSITY OF FREIBURG   (Germany)

^b UNIVERSITY OF FREIBURG   (Germany)

^c LEUPHANA UNIVERSITY OF LÜNEBURG   (Germany)

Author keywords

Anaerobic; Biodegradation; Photodegradation; Photolysis; Risk; Toxicity

Indexed keywords

ABIOTIC TRANSFORMATION; ANAEROBIC; ANAEROBIC BIODEGRADATION; ANAEROBIC BIOTRANSFORMATION; ANAEROBIC DEGRADATION TEST; ANTIPSYCHOTIC DRUG; AQUATIC ENVIRONMENTS; BACTERIAL DENSITY; BIODEGRADATION TEST; CHROMATOGRAPHIC COLUMN; COMPLEX MATRICES; ECOTOXICOLOGICAL; ENVIRONMENTAL CONDITIONS; ENVIRONMENTAL FATE; ENVIRONMENTAL PATHWAYS; HIGHER ORDER; HPLC-MS; ISOMERIC COMPOUNDS; LC-MS N; LOW CONCENTRATIONS; PHOTOLYSIS PRODUCTS; PHOTOPRODUCTS; POTENTIAL TRANSFORMATIONS; SEPARATION TECHNIQUES; TEST SAMPLES; TOXIC EFFECT; TRANSFORMATION PRODUCTS; XENON ARC LAMPS; ZAHN-WELLENS TEST;

BACTERIA; BIODEGRADATION; BOTTLES; CHROMATOGRAPHY; DEGRADATION; DRUG PRODUCTS; EXPERIMENTS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LEAD COMPOUNDS; LINEAR TRANSFORMATIONS; MICROBIOLOGY; PHOTOLYSIS; RISKS; TEACHING; TOXICITY;

PHOTODEGRADATION;

CHLORPROMAZINE; XENON;

AEROBIC METABOLISM; ANAEROBIC METABOLISM; AQUATIC ENVIRONMENT; ARTICLE; CHEMICAL STRUCTURE; COMPUTER PROGRAM; CONTROLLED STUDY; DRUG DEGRADATION; DRUG TRANSFORMATION; ECOTOXICOLOGY; FLUORESCENCE ANALYSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IRRADIATION; MASS SPECTROMETRY; MICROBIAL DEGRADATION; NONHUMAN; PHOTODEGRADATION; PHOTOLYSIS; PRIORITY JOURNAL; RISK ASSESSMENT; SLUDGE; SUNLIGHT; ULTRAVIOLET RADIATION;

AEROBIOSIS; ANAEROBIOSIS; ANTIPSYCHOTIC AGENTS; BIODEGRADATION, ENVIRONMENTAL; CHLORPROMAZINE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ECOTOXICOLOGY; ENVIRONMENTAL REMEDIATION; MASS SPECTROMETRY; OXYGEN; PHOTOLYSIS; PRESSURE; SEWAGE; WATER POLLUTANTS, CHEMICAL;

BACTERIA (MICROORGANISMS);

EID: 84858265422     PISSN: 15700232     EISSN: 1873376X     Source Type: Journal    
DOI: 10.1016/j.jchromb.2012.01.022     Document Type: Article

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