Cloning and molecular characterization of three arylamine N-acetyltransferase genes from Bacillus anthracis: Identification of unusual enzymatic properties and their contribution to sulfamethoxazole resistance

Biochemistry

Volumn 46, Issue 23, 2007, Pages 7069-7078

  Pluvinage, Benjamin ^a   Dairou, Julien ^a   Possot, Odile M ^b,c   Martins, Marta ^a   Fouet, Agnès ^b,c   Dupret, Jean Marie ^a   Rodrigues Lima, Fernando ^a  

^a UNIVERSITÉ PARIS DESCARTES   (France)

^b INSTITUT PASTEUR   (France)

^c CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTICS; ANTIBODIES; CATALYSIS; CLONING; ESCHERICHIA COLI; GENES; HYDROLYSIS; PATHOGENS;

ARYLAMINE; FUNCTIONAL EXPRESSION; RECOMBINANT BACTERIA; XENOBIOTICS;

ENZYMES;

2 FLUORENYLAMINE; AMINOSALICYLIC ACID; AROMATIC AMINE; ARYLAMINE ACETYLTRANSFERASE; BACTERIAL PROTEIN; DRUG METABOLIZING ENZYME; ENZYME ANTIBODY; HYDRALAZINE; MESALAZINE; RECOMBINANT ENZYME; SULFAMETHOXAZOLE; SULFONAMIDE; XENOBIOTIC AGENT;

ACETYLATION; ANTIBIOTIC RESISTANCE; ARTICLE; BACILLUS ANTHRACIS; BACTERIAL GENE; BACTERIAL GENETICS; BANATA GENE; BANATB GENE; BANATC GENE; DETOXIFICATION; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME MECHANISM; ENZYME STRUCTURE; ENZYME SUBSTRATE; ESCHERICHIA COLI; GENE EXPRESSION; HYDROXYLATION; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; ARYLAMINE N-ACETYLTRANSFERASE; BACILLUS ANTHRACIS; BASE SEQUENCE; CLONING, MOLECULAR; CONSERVED SEQUENCE; DNA PRIMERS; DNA, BACTERIAL; DRUG RESISTANCE; GENE EXPRESSION REGULATION, BACTERIAL; MOLECULAR SEQUENCE DATA; OPEN READING FRAMES; POLYMERASE CHAIN REACTION; RECOMBINANT PROTEINS; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; SULFAMETHOXAZOLE;

BACILLUS ANTHRACIS; BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; EUKARYOTA; PROKARYOTA;

EID: 34250223080     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi700351w     Document Type: Article

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